HIV Life Cycle

The life cycle of the HIV virus is a multi-step process. This animation describes the structure of the HIV virus, receptor-mediated attachment to CD4 lymphocytes, viral envelope fusion with the CD4 cell membrane, uncoating and release of viral RNA into the target cell cytoplasm, reverse transcription leading to the formation of viral DNA, viral DNA genomic integration, transcription of viral mRNA, and translation of viral proteins leading to the assembly of new viruses.
This animation is narrated by Dr. Mark Wainberg, who was Professor of Medicine and Microbiology at McGill University, Montreal, Quebec, a leading Canadian AIDS researcher and activist.
To learn more visit www.AnimatedHIVScience.com

Пікірлер: 128

  • @drewdurant3835
    @drewdurant38354 жыл бұрын

    I don’t understand how y’all figured this out....

  • @daisy0rnament
    @daisy0rnament4 жыл бұрын

    This is such an amazing animation and lesson. Thank you.

  • @lewismccane3449
    @lewismccane34494 жыл бұрын

    great vid, good explaination of this viral production.

  • @robertcaling9267
    @robertcaling92674 жыл бұрын

    This Virus is so smart... I'm not losing hope that one day we will be able to find its weakness.

  • @dogukanaslan9713

    @dogukanaslan9713

    4 жыл бұрын

    We need. 😪😔 i hope too

  • @TheFilipFonky

    @TheFilipFonky

    4 жыл бұрын

    Not catching it works really well

  • @lewiszim

    @lewiszim

    4 жыл бұрын

    We have found some weaknesses. We can't cure someone who has HIV, but PrEP can effectively work as a vaccine. If taken regularly, it can be 99% effective in preventing transmission. Combine it with a condom, and transmission can drop to near zero. We must make this drug more widely available!

  • @lhaviland8602

    @lhaviland8602

    4 жыл бұрын

    We kinda have, thankfully.

  • @utopiasound9328

    @utopiasound9328

    4 жыл бұрын

    this is not real as mathematics game of life that virus by this mecanisme not multiply as the first one die and next one get born so we have the same number 1 this not real

  • @tanapornsritip3052
    @tanapornsritip30523 жыл бұрын

    Love this animation

  • @leepeien9738
    @leepeien97384 жыл бұрын

    Thank you, this really helped me to visualise HIV life cycle

  • @ASM_Minds
    @ASM_Minds3 жыл бұрын

    That's awesome! thank you!

  • @nayababbasi3337
    @nayababbasi33374 жыл бұрын

    It’s an amazing video that’s help alot me in my virology presentation👍🏿👍🏿👍🏿

  • @nerosonic
    @nerosonic4 жыл бұрын

    awesome video! nice explanation

  • @ransaeed8202
    @ransaeed82023 жыл бұрын

    Unbelievable 😭😭😭😭 The most amazing video 😡😡🤩❤️❤️❤️

  • @jorenaut6660
    @jorenaut66605 жыл бұрын

    Great video! Helping me with my virology revision, thanks!

  • @mika_a05
    @mika_a057 ай бұрын

    Thank you so much your explanation was perfect

  • @jonathankevin7527
    @jonathankevin75274 жыл бұрын

    Very good presentation keep it up brother

  • @SilenceInTheBliss
    @SilenceInTheBliss2 жыл бұрын

    Wow. You made this so easy to understand. Thank you!

  • @mwakaaliciachimbila1242
    @mwakaaliciachimbila12424 жыл бұрын

    Wow,iv learnt a lot

  • @umakantshinde3049
    @umakantshinde30493 жыл бұрын

    Excellent video😍

  • @elliebayat8309
    @elliebayat83094 жыл бұрын

    Great explanation, Thank you

  • @desamgurivireddy2823
    @desamgurivireddy28233 жыл бұрын

    Thankyou very much

  • @chandrakala8491
    @chandrakala84914 жыл бұрын

    well explained

  • @rideonwater2
    @rideonwater24 жыл бұрын

    could the viral protease in the cytoplasm ever eventually dissolve or denature over the course of the life of the cell?

  • @novantembo2288
    @novantembo22884 жыл бұрын

    This is equally, seemingly well designed. Curiously, those who believe in intelligent design never focus on such devious design.

  • @christopheschouwey1288

    @christopheschouwey1288

    4 жыл бұрын

    I have had the same question for some time. Viruses are so complicated and extraordinary that they make me believe in God. Same for cancers, they know how to do so many things, it is just awesome. The more I learn about them, the more I admire them. I would never have imagined.

  • @iloveamerica1966

    @iloveamerica1966

    4 жыл бұрын

    @Rumpel Felt "it's just nature" is just an opinion. Heck, maybe it's 'just' alien, sent to cause smart humans to figure more how this all works.

  • @rehanaqasimqasim3392
    @rehanaqasimqasim33923 жыл бұрын

    Very helpful 👍

  • @shreyaseedas2048
    @shreyaseedas20483 жыл бұрын

    Waoooo jxt amazingggg ❤️

  • @ulukbekzhumaliev2588
    @ulukbekzhumaliev25883 жыл бұрын

    Good explanation. However I couldn't find and get HIV has two RNAs. In the last step, from where the HIV gets these two RNAs?

  • @Manny007.
    @Manny007.2 жыл бұрын

    Hoping for a cure

  • @krishnashaw9478
    @krishnashaw94784 жыл бұрын

    Plz upload hepatitis B virus animation....plz

  • @vanshikabule6528
    @vanshikabule65284 жыл бұрын

    Hi that's exallent to understand HIV life cycle 👍👍👍

  • @Anthony-vp1jb
    @Anthony-vp1jb3 жыл бұрын

    Nice video 👍

  • @fahadmustafa503
    @fahadmustafa5034 жыл бұрын

    Wow amazing lec i completely understand thank you so much

  • @shaunlally3986
    @shaunlally39864 жыл бұрын

    Please a cure for hive now

  • @samlak7102
    @samlak71024 жыл бұрын

    And they say god dosn't exist, all this complexity is by itself!

  • @manojkumarbarnawal2396
    @manojkumarbarnawal23964 жыл бұрын

    Why purity is necessary for future generations.

  • @usmansyed7632
    @usmansyed76324 жыл бұрын

    great

  • @keithwilson6060
    @keithwilson60604 жыл бұрын

    I wish the presenter had gone into how long this lifecycle takes. Anybody know?

  • @marquise49
    @marquise494 жыл бұрын

    thx for this animation but u don't explain very well how immature virus became a mature virus

  • @squidgame3319
    @squidgame33193 жыл бұрын

    Awesome video.. thanks

  • @sobhancosmology2931
    @sobhancosmology29316 ай бұрын

    Is there a way to destroy gps120 when they stick to the outer layer of Td4 cells and after that matrix core can't go out with out them ? Can a specialist answer my question plz ?

  • @miltonm1196
    @miltonm11964 жыл бұрын

    It's super vedio

  • @ameyas7726
    @ameyas77264 жыл бұрын

    3:20 Oh No! the Enterprise is under attack!!!...quick Lieutenant how many photon torpedoes do we have???

  • @AnkeetKumar
    @AnkeetKumar4 жыл бұрын

    One of my junior asked me does the entry of viral DNA increases length of Host Chromosome size . Now I am confused .?

  • @ameyas7726

    @ameyas7726

    4 жыл бұрын

    Yes it increases by the length size of the viral DNA!

  • @drmuhammadanwar741
    @drmuhammadanwar7414 жыл бұрын

    fantabulous

  • @nirendrakerkettasdiary5332
    @nirendrakerkettasdiary53324 жыл бұрын

    SIR NEXT TIME PLEASE INSERT SUBTITLE ....BUT ALLOVER VIDEO IS VERY INFORMATIVE....

  • @user-cy1ms7se2x

    @user-cy1ms7se2x

    6 ай бұрын

    If you turn on the ''CC'' -subtitles... there will b no need... 🙃

  • @barnardomhanga2505
    @barnardomhanga25054 жыл бұрын

    I have got a concept concerning with HIV

  • @messpilo
    @messpilo4 жыл бұрын

    If they know so much about the virus why they can not cure it..? It seems that we don't know much yet.

  • @theeverythingchannel1112

    @theeverythingchannel1112

    4 жыл бұрын

    It's not that easy sir

  • @theeverythingchannel1112

    @theeverythingchannel1112

    4 жыл бұрын

    It's a very complex virus

  • @troydennis96

    @troydennis96

    4 жыл бұрын

    Michalis Michaelides curing this virus is impossible. Once integrated in the host genome there is no targeted excision of the viral DNA. There are several treatments available but curing someone entirely once infected is nearly impossible. There are currently some speculated ways to attempt to inactivate the virus prior to host integration but this is not a cure and more-so a preventative measure. The other thing that makes it incredibly difficult is a lot of treatments focus on using the body’s immune system, however this virus targets that very immune system.

  • @sanane66543

    @sanane66543

    4 жыл бұрын

    Michalis Michaelides we dont know shit every time a virus comes out humans always are waaay too slow or cant find any cure for it

  • @oldmangranny5oldmangranny56

    @oldmangranny5oldmangranny56

    4 жыл бұрын

    Because the HIV DNA stays dormant in the host's genome until the host cell is activated. Which could be years.

  • @joshuashorter
    @joshuashorter3 жыл бұрын

    It is real and powerful

  • @anthonymunene8061
    @anthonymunene80614 жыл бұрын

    We need cure in Kenya please

  • @cn83
    @cn834 жыл бұрын

    wow! 😍

  • @usa4u123
    @usa4u1233 жыл бұрын

    I have a device to stay away from that....

  • @muhammadwaleedulislam5572
    @muhammadwaleedulislam55723 жыл бұрын

    Legendary

  • @muhammadshafeeq7322
    @muhammadshafeeq73224 жыл бұрын

    Plz clear me about that there are two Viral RNAs which are identical to each other but only one is being used by reverse transcriptase to made it into DNA then what is use of second viral RNA ??? And why there are two RNAs in HIV???

  • @asmasattar452

    @asmasattar452

    4 жыл бұрын

    the second RNA is degraded

  • @princessmike8712

    @princessmike8712

    4 жыл бұрын

    The reverse transcriptase enzyme converts the single strand viral RNA into a short-lived RNA-DNA duplex. The original RNA is degraded by RNase 11 to allow creation of a full length double stranded DNA copy of virus which will fit into the human DNA.

  • @muhammadshafeeq7322

    @muhammadshafeeq7322

    4 жыл бұрын

    @@princessmike8712 thnx

  • @preethir8153

    @preethir8153

    3 жыл бұрын

    @@princessmike8712 does it mean a pair of viral ds DNA enter the host cell, (or) only one RNA is being used to develope a DNA and another strand is degraded😅😅

  • @sandrodream5418
    @sandrodream54183 жыл бұрын

    Only God could create this Incredible mechanism

  • @WyattXD
    @WyattXD4 жыл бұрын

    It can't have a life cycle if it isn't living!

  • @humsubkapakistan4995
    @humsubkapakistan49954 жыл бұрын

    انسان ایسا کیمرہ کب بناے گا جو حقیقی وائرس کی وڈیو بنا سکے۔

  • @tumarzatulanbekova4592
    @tumarzatulanbekova45924 жыл бұрын

    👏🏻👏🏻👏🏻👏🏻👏🏻👏🏻👏🏻

  • @kimchi1837
    @kimchi18374 жыл бұрын

    Ay sakit sa ulo

  • @doctorvimalkatarmal4704
    @doctorvimalkatarmal47044 жыл бұрын

    I hate these smartest virus😠😠😠😠😠

  • @francoskills5928
    @francoskills59284 жыл бұрын

    When you realize that one virus is not something alive, its a particule, it’s ridiculously obvious that is human make and that is make for kill. Somebody can tell me since when something inert do cycle of something? Since when something not alive can don mutation but stay the same sometime and sometime not? Since when a particule can reproduce itself? Since when a particules from no where, alone in the nature can create a mecanism inside itself, a mecanism so complexe that we cannot figure it out , and to be a particule? It is possible that randomly molecules and atomes do something like that alone. And it not only that. It a particule but that want to be alive. That reproduce itself for want ? That not alive why that want to reproduce itself ? Only one thing can answer all those question. How somebody can do it to somebody? How much this person can hate us? Do you believe that love can fix it? Can we love enough for fix it. Do we want to fix it? Its so obviously human make that we just decided to do like we don’t know because to know implicate to ask to ourself we somebody hate us as it. What we did that hurt somebody enough for pushing him to do something disgusting like it ?

  • @AJ-tz2lh

    @AJ-tz2lh

    4 жыл бұрын

    Wtf.... I spent way too long trying to understand this comment.

  • @henryramen1438

    @henryramen1438

    4 жыл бұрын

    AJ420 Same either this guy’s first language is not English or he’s waaaaay too high on acid.

  • @villebooks

    @villebooks

    4 жыл бұрын

    @@AJ-tz2lh Transcription issues x)

  • @Kori114

    @Kori114

    4 жыл бұрын

    LOL WUT?

  • @marziasultana4124

    @marziasultana4124

    4 жыл бұрын

    @@AJ-tz2lh Hahaha.. BTW don't use bad language

  • @p.burrowes8660
    @p.burrowes86607 ай бұрын

    Really great video. Evil in virus form.

  • @maciejorzechowski6497
    @maciejorzechowski64974 жыл бұрын

    Look like coronavirus...

  • @vydai2702
    @vydai27023 жыл бұрын

    Poor dog I liked my own commet how sad.

  • @Nemesis816
    @Nemesis8164 жыл бұрын

    He repeats himself three times, annoying to listen to but very informative