High Cholesterol on a Low carb Diet

Ғылым және технология

One of the most common questions I’ve been asked by my patients on a low-carb diet is whether they should be concerned about high cholesterol levels.
Is high LDL cholesterol a reliable indicator of heart disease risk in people on low-carb diets, especially if they don’t have any other significant risk factors like high blood pressure or insulin resistance?
And do statin drugs really reduce the risk of heart disease and early death in people on low-carb diets with high cholesterol that haven’t had a cardiovascular event like a heart attack or stroke yet?
These are exactly the questions I answer in this video, so keep watching!
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Recommended Videos:
› Low-carb Diet for Diabetes and Blood Sugar DIsorders: • Low-carb Diet for Diab...
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Resources & Related Articles:
› The Low Down on Low Carb ebook: chriskresser.com/low-carb/
› The Diet-Heart Myth ebook: chriskresser.com/heart-disease/
› QRISK®2-2017 risk calculator: www.qrisk.org/2017/
› Mortality among patients with familial hypercholesterolemia: a registry-based study in Norway, 1992-2010: pubmed.ncbi.nlm.nih.gov/25468...
› Statin therapy is not warranted for a person with high LDL-cholesterol on a low-carbohydrate diet: journals.lww.com/co-endocrino...
› Coronary artery calcium score and risk classification for coronary heart disease prediction: pubmed.ncbi.nlm.nih.gov/20424...
› Absence of coronary artery calcification and all-cause mortality: pubmed.ncbi.nlm.nih.gov/19520...
› Coronary Artery Calcium and Cardiovascular Events in Patients With Familial Hypercholesterolemia Receiving Standard Lipid-Lowering Therapy: pubmed.ncbi.nlm.nih.gov/30448...
› Systematic review and meta-analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors: pubmed.ncbi.nlm.nih.gov/22905...
› Virta Health studies: www.virtahealth.com/research
› Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S): pubmed.ncbi.nlm.nih.gov/7968073/
› Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial: pubmed.ncbi.nlm.nih.gov/12457...
› Should people at low risk of cardiovascular disease take a statin?: www.bmj.com/content/347/bmj.f...

Пікірлер: 52

  • @RiverReeves23
    @RiverReeves23 Жыл бұрын

    I hope one day, this will be the standard of care. Thanks Chris.

  • @Debkuwait
    @Debkuwait Жыл бұрын

    Thank you for this. Very needed 👍🏻👍🏻

  • @Godsgirl1954
    @Godsgirl1954 Жыл бұрын

    I thank you so much for this! My last bloodwork showed excellent levels of everything, very low inflammation, high HDL and low triglycerides - all ratios excellent. LDL was high and that was all the doctor focused on even though I mentioned what I just said and that my cardiac risk was extremely low and I eat a very low carb diet. I will share this info with her - thank you!

  • @jeffj318

    @jeffj318

    15 күн бұрын

    Shake the dust from your feet and don't look back. If your doctor is only concerned about LDL it's time to leave the doctor mill.

  • @daisiesushitam984
    @daisiesushitam9842 ай бұрын

    Clear and to the point. Bravo!

  • @stellabrophy2715
    @stellabrophy271510 ай бұрын

    Superb!

  • @celiamoriarty
    @celiamoriarty Жыл бұрын

    I appreciate all this information. It is very hard to take it all in without text. Previously Chris's updates had text or watch options.

  • @chriskresser

    @chriskresser

    Жыл бұрын

    Hi Celia! If you hit the "CC" icon at the bottom right of the screen you can turn on text captions for the video. Hope this helps!

  • @ArcoZakus

    @ArcoZakus

    5 ай бұрын

    Tap "...more" under the video's title, then (Show transcript).

  • @brenwesterland6306
    @brenwesterland6306 Жыл бұрын

    Thank you so much for your helpful information! I know this is random, but you were quite prompt in replying to my youtube comment last time and I cant think of a way to get in contact with you.. so here I am again. My wife just got pregnant and Im trying to consume as much info as I can. Ive read almost all of your articles on your website and have been on the fence about getting your baby course--wondering if its up to date/worth it.. if you really think it is a resource that will add new and concrete guidance then Ill trust your word and give it a try Also looking at the different articles you made about nutrition Im feeling like most base prenatals arent quite the right fit.. would really love if you also added a prenatal line to your Adapt Natural line! Finding a hard balance between natural diet and supplements that don't overlap enough or do so too much and then Im left with dosing individually which is rough when its not my profession nor area of expertise. Anywho love all of you information and again thank you so so much!

  • @magnegronnevik8064
    @magnegronnevik80648 ай бұрын

    ❤Thank You!

  • @shanedraper240692
    @shanedraper2406925 ай бұрын

    I am 31 years old with fh and had a heart attack 2 years ago. I started keto a month ago and my ldl has shot up, my HDL has gone up too

  • @frostfree7
    @frostfree72 ай бұрын

    Do you have any data on whether a keto/low saturated fat diet raises LDL as much as a keto/high saturated fat diet?

  • @robertdaymouse3784
    @robertdaymouse3784 Жыл бұрын

    i would be interested to know if the test results for Ezetimbe are similar to the test results for Statins for persons on a low carb diet with low Trigs and good HDL.

  • @beenflying1

    @beenflying1

    8 ай бұрын

    I have tried them and they are just as bad as statins, when it comes to muscle and joint pain. I cannot take either. Fortunately, I have gone on a low carb diet and no longer need them. 😊

  • @santiagojaramillo3079
    @santiagojaramillo3079 Жыл бұрын

    What about high APO B and Lipo(a) biomarkers associated with cvd?

  • @FreedomFox1
    @FreedomFox13 ай бұрын

    What do you define as low triglycerides or high HDL? Also, isn’t it true that driving ldl cholesterol low enough will make heart disease risk basically zero?

  • @EuJiaHan
    @EuJiaHan3 ай бұрын

    If one on keto Carnivore diet, non hdl and LDL slightly a bit high and didnt fast for twelve hours before take the test. What does this mean ? If this ok ?

  • @anna_pinnock
    @anna_pinnock Жыл бұрын

    Thank you, very helpful. Is the mechanism behind this phenomenon known? Could there be a link between increased TGs consumption and VLDL particles?

  • @chriskresser

    @chriskresser

    Жыл бұрын

    One theory is that saturated fat consumption interferes with the ability of LDL receptors on cells to remove LDL particles from the blood. But it's worth noting that not everyone experiences an increase in LDL with an increase in saturated fat consumption.

  • @theunknownsamurai7426
    @theunknownsamurai7426 Жыл бұрын

    Is there a correlation between low-carb diets and high cholesterol levels.

  • @faitharnold4643

    @faitharnold4643

    Жыл бұрын

    Yes, but it's not what most people have been lead to believe. Low carb diets mean more of the body's energy requirements are being met by fat instead of carbs. Fat is a cleaner-"burning" fuel that doesn't result in free radicals being produced inside of the mitochondria. But fat has to be transported arond the body wrapped up in little packets of protein (with a small amount of cholesterol as part of the structure). That's why they are called "lipoproteins". Fat globules cannot ever be allowed to just float around in the bloodstream by themselves or they would make a gooey mess, and they would be very damaging. So, yes, on a higher fat diet there will be more lipoprotein fat transport particles, but no, it isn't really "cholesterol", and they have nothing to do with causing heart disease!

  • @suedunne7774
    @suedunne7774 Жыл бұрын

    How about if I'm type 1 but also have high lpa? Low carb works best for my Type 1, but don't love my high lpa score!

  • @chriskresser

    @chriskresser

    Жыл бұрын

    It's true that Lp(a) is an independent risk factor for CVD. I'd assume that many people in the studies I mentioned in the video that were on LCDs and had high LDL also had high Lp(a). But they weren't at higher risk for CVD. This is still an open question, and I wish we had more research to guide us here.

  • @suedunne7774

    @suedunne7774

    Жыл бұрын

    Thanks Chris! I do what I can, and it was recommended to take bolouke daily to help. Here's to hoping!

  • @lorizitzmann6018
    @lorizitzmann6018 Жыл бұрын

    Does this also apply to those of us with APOE4?

  • @chriskresser

    @chriskresser

    Жыл бұрын

    I discussed the contribution of APOE4 with Dr. Dale Bredesen on a podcast I did with him a while back. You can read the transcript here: chriskresser.com/prevention-and-treatment-of-alzheimers-from-a-functional-perspective-with-dr-dale-bredesen/. Just search for "APOE4" and you'll find the relevant bits, but here's the short version: the increased risk that APOE4 confers appears to be most relevant for people following a standard American diet and lifestyle.

  • @diannea.2587
    @diannea.2587 Жыл бұрын

    What is "FH"?

  • @PorcupineMusic

    @PorcupineMusic

    Жыл бұрын

    Familial hypercholesterolemia. Basically means genetically high cholesterol

  • @diannea.2587

    @diannea.2587

    Жыл бұрын

    @@PorcupineMusic Thank you Chris!

  • @ArcoZakus

    @ArcoZakus

    5 ай бұрын

    ( 1:55 )

  • @Gesundheit888
    @Gesundheit8885 ай бұрын

    Keto or carb diets only increase LDL in LMHR. Not in obese people.

  • @nutritionhealthandriskprev6228
    @nutritionhealthandriskprev6228 Жыл бұрын

    The link between high cholesterol and cardiovascular disease is very well-estalished and very solid. I don't know why people like you insist in denying this fact, at the expense ofother people's health. You are so shameless to say all of this and reference a studies that says exactly the opposite: "Conclusion: Despite access to modern dietary counseling and prescribed lipid-lowering drugs, FH patients still have significantly increased CVD mortality compared with the general Norwegian population." "Mean age of CVD deaths among the FH patients in the UCCG Registry was 62.2 years for both sexes combined, with 57.2 years for men and 67.2 years for women. According to data from the Norwegian Cause of Death Registry, the mean age of CVD deaths in the general population was much higher: 79.0 years from 1992 to 1995 and 81.0 years from 1996 to 2010." Their risk doesn't go down with age. Only the relative risk goes down with age. People with FH have higher risk at any age. The study explains this reduction in relative risk like this: "Most FH patients are well aware of premature CVD in the nearest family members and have repeatedly received professional diet and lifestyle advice."

  • @chriskresser

    @chriskresser

    Жыл бұрын

    Thanks for your comment. It's always helpful to look at the totality of the evidence, which I referred to in the video, like this large review showing that people on LCDs (with higher intake of saturated fat) see a reduction in numerous CVD risk factors. pubmed.ncbi.nlm.nih.gov/22905670/ Virta Health has a good summary of the research on this topic on their website as well. www.virtahealth.com/research

  • @nutritionhealthandriskprev6228

    @nutritionhealthandriskprev6228

    Жыл бұрын

    @@chriskresser I read all the studies you referenced. There is no doubt that a ketogenic diet is effective for weight loss, like any diet that eliminates sugar and refined grains. The review you are sharing analyzes obese patients, and the interventions are short term (few weeks to few months). It is no surprise that their cardiometabolic markers improved, just like they improve in obese people with the potato diet.

  • @markcarter710

    @markcarter710

    Жыл бұрын

    @@nutritionhealthandriskprev6228 Maybe some day you'll return from the '80s and get current. Remember, just because you disagree with something doesn't make that something wrong.

  • @nutritionhealthandriskprev6228

    @nutritionhealthandriskprev6228

    Жыл бұрын

    @@markcarter710 Is that even an argument? The atherogenic effects of LDL-cholesterol are very robust. It's not that I disagree, so it's wrong. The evidence is so overwhelming that it's incontestible. You guys feel cool because you deny science, kinda like flat earthers. High LDL causes atherosclerosis; both big LDL and small dense LDL; both in the presence of inflammation or not; with or without hypertension; with or without high triglicerides. It's not very difficult, LDL-C is an independent risk factors, and it is causal. It's not the only factor, but it is a very important one. I do understand that LDL-C is not the best predictor of cardiovascular events, and that it is not the best measure, and that the size of molecules matter. I'm not stuck in the 80s. But despite all of that, LDL-C remains a factor in cardiovascular disease, and it always will because LDL-C CAUSES atherosclerosis.

  • @lastlime3792

    @lastlime3792

    8 ай бұрын

    Lower cholesterol =more death.

  • @takuroshinji2445
    @takuroshinji2445 Жыл бұрын

    Ate low carb for over a year,my triglycerides went to 125, cholesterol to 260 ldl to 202 and hdl down to 33..... starting to think low carb and carnivore is just as dangerous as processed foods

  • @YouTuber-ep5xx

    @YouTuber-ep5xx

    6 ай бұрын

    On low-carb high-fat diet, my trigs fell from 200+ to 60s, my HDL rose from low 20s to around 50. I believe this is pretty typical.

  • @nutritioncoachjo

    @nutritioncoachjo

    3 ай бұрын

    I wouldn’t assume it’s the carnivore or keto diet that gave you those cholesterol numbers. I highly recommend you watch Dr. Ken Berry’s videos who will explain why carnivore is not dangerous and will tell you exactly what you need to do to get better numbers.

  • @jeffj318

    @jeffj318

    14 күн бұрын

    You are numbers are not typical of a low carb diet. You don't sate what you're eating plan was or is today. On a low carb way of eating, your HDL should rise, your triglyceride should decrease into the normal or below normal range although your total cholesterol and your LDL could rise.

  • @jeffj318

    @jeffj318

    14 күн бұрын

    ​@@KZreadr-ep5xxYour answer is a good answer. This is typical of what should happen and the OP might just be putting out BS.

  • @jeffj318

    @jeffj318

    14 күн бұрын

    ​@@nutritioncoachjoYour answer is exactly correct. 🎉

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