In this month's "Hot Topic," Rajiv Pruthi, M.B.B.S., discusses heparin induced thrombocytopenia, approach diagnosis, and the role of the functional serotonin release assay.
0:00 Introduction
0:45 Learning Objectives
1:15 HIT Background
1:55 Case Example
3:22 HIT Diagnosis Algorithm
4:11 HIT Recognition
4:50 HIT Pre-Test Probability Scoring
5:52 Predictive Value of 4Ts
8:20 HIT Laboratory Assays
9:32 Mayo Clinic SRA Method
10:20 Interpretation
11:12 Correlation
12:07 Positive ELISA and Negative SRA
12:45 HIT ELISA Negative and SRA Indeterminate
13:26 HIT Negative SRA
13:58 Conclusions