Pharmacology - ANTICOAGULANTS & ANTIPLATELET DRUGS (MADE EASY)
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Anticoagulants, commonly referred to as blood thinners, are drugs that prevent or reduce coagulation of blood, prolonging the clotting time. Antiplatelet drugs, also known as a platelet aggregation inhibitors, decrease platelet aggregation and inhibit clot formation. These drugs play an important role in the treatment of various disorders such as myocardial infarction, thrombotic stroke and venous thromboembolism. This pharmacology lecture covers topics such as pathophysiology of blood clot formation and platelet function; activation, aggregation, cross-linking; ADP receptors, glycoprotein IIb/IIIa receptors, cyclooxygenase-1 (COX-1) enzyme, fibrinogen, fibrin mesh, coagulation cascade; intrinsic & extrinsic pathways, clotting factors, antithrombin, heparin induced thrombocytopenia, INR, plasmin, and plasminogen; mechanism of action of platelet inhibitors, anticoagulants, thrombolytic agents, and drugs used for treatment of bleeding. Drugs mentioned include; Aspirin, Clopidogrel, Ticagrelor, Ticlopidine, Prasugrel, Abciximab, Eptifibatide, Tirofiban, Heparin, low molecular weight heparins; Enoxaparin, Dalteparin, Protamine sulfate, Apixaban, Rivaroxaban, Univalent & Bivalent direct thrombin inhibitors; Argatroban, Dabigatran, Bivalirudin, Desirudin, Warfarin, Vitamin K, Alteplase, Reteplase, Tenecteplase, Urokinase, Streptokinase, Aminocaproic acid, Tranexamic acid.
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0:00 Platelet plug formation
2:04 Platelet aggregation inhibitors
5:34 Coagulation cascade
7:38 Anticoagulants
12:03 Warfarin
14:11 Thrombolytics
Пікірлер: 419
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@Doctor____Z
7 ай бұрын
Perfect
Update: an antidote for apixaban and rivaroxaban is now available: Andexanet alfa. Came out in 2018, one year after this video was uploaded.
@heiitsme182
3 жыл бұрын
thank you for information
@Padmashrinaren
3 жыл бұрын
Thanks 👍👍
@user-jk1ez3jf5d
2 жыл бұрын
Thank you
@N4REG
2 жыл бұрын
Also, Dabigatran has an antidote, Praxbind
@Ola-ox4bc
Жыл бұрын
Idarucizumab a monoclonal antibody
It's nice to have a diagram of the cascade and then interject each drug class where it acts. Thank you! This is how all topics should be taught by all teachers!
since i was pharmacy student i used to watch your videos before mid & final exams and it help me to remember things & make it easier now i'm officially graduated pharmacist but still love watching your videos😅 so i want to say thank u so much for making pharmacology easier on me ❤️🧸
@shuaibumansuryushau5921
11 ай бұрын
From which country are you from Ma??
@Azharali-sk7yw
4 ай бұрын
I'm doing my b.pharm 3rd year right now.. Is there any scope for pharmacy after graduation???? Because, I don't see any scope in India as they are paying very low for the pharmacists.
Please keep making those videos, it was organized, simple, and really straightforward. You just save my 5-hour listening to recording lectures. Thank you so much
this video is absolute gold. thank you so much for taking your time to make this, you deserve an award.
Coagulation cascade are the ones I found hardest at med school and it was a pain to revise when comes to finals then I forget about it. Now I'm preparing for core training exams and actually find this video more helpful than ever. I never understood this topic any clearer (I guess with more clinical experience it also helps to understand bit more). Thanks so much for making this video.
This was perfect from beginning to end. Information logically categorized, great talking speed, use of graphics that helped anchor understanding... bless you for taking the time to make this! First time seeing your videos, instantly subscribed. Looking forward to watching the rest of your videos through Pharmacology class!
@nishamanoj3099
4 жыл бұрын
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@VV-lj7ns
2 жыл бұрын
You are conveying little faster
@VV-lj7ns
2 жыл бұрын
And your slang make it us difficulty in understanding in some places
I would just like to say thank you for captioning your content! As a subtitle person, you're making it easier for me to learn, so thank you.
Amazing video. I have been struggling with this topic but this has made it very easy for me . Thank you.
WHO KNEW IT WAS THIS EASY!!! I can't thank you even for saving my life
thanks for keeping your lectures short, simple and to the point
Great summary video! thanks for the post. It was very helpful. I like that you give examples of all the drugs in each class and their mechanisms with visuals. This helps to solidify the information for visual learners.
I was struggling with this for hours then I found your video This is the freaking best!
@nishamanoj3099
4 жыл бұрын
kzread.info/dash/bejne/q6Kisq-glKi8ZbA.html
Thank you for the great video! The reversal agents discovered after this video was made: for apixaban it’s andexanet alfa, and for dabigatran it’s idarucixumab.
Excellent video! Covers everything. Really grateful to you for making this!😀
EXCELLENT - perfect for nursing students. Thanks for making this!
you are literally a life saver!!! thank you so much for making my life and concepts easier. God bless you
I have just discovered you and u have no idea how grateful I am.
This was the best video for the Hemostasis drugs!! Thank you!!! Perfect!!!!
The best lecture so far of this very complicated topics and the use of picture aids is just superb!❤
Excellent video. Well organized, clear, and logically explained. Thank you!
I am fortunate to find your channel and watch your lectures. They are directly oriented to the point and easy to understand. Thanks so much!!!!
you are an amazing person who make everything in pharmacology easier and simple (may god bless you )
Man you’re the best... love your lectures~
Thank you so much! I can't believe I was struggling with them from 2 hrs and I got it at once or twice from a 16 min video.
Oh my god! I was literally waiting for the upload of video on this topic. Sir, You make learning process in pharmacology so simple and easy to understand. I owe all my good marks to your lectures! Thanks a ton❤
@mmss4428
6 жыл бұрын
Avneeta Swashna
I can't thank you enough, God bless you, may you achieve more than what you wish for💕
I watched the first video from your channel 6 years ago when i was in semester one 1 trynna understand autonomic NS drugs. and now I am doing my internship and wanted to revise. thank you for being with me throughout the journey
I'm officially graduated pharmacist still love to watch ur videos , thanku so mch for making pharmacology easier
Thank you so much, so clear and simple May God bless you
Brief but very educative! Thank you. God bless!
Hi, Can you make video on Antiemetics.. And Thanks a lot for making the toughest topics of pharmacology EASIEST..!
Amazing video, pal! Thanks for making the difference in my study process!!!!
Well simplified... Great job.. Thank you.
This video is incredible! So helpful! Thank you so much!!
Thank you so much! So simple and amazing!
The best video of the topic! Thank you!
I loved this- straight to the point.
Dude, this is awesome! Thnk you from a struggling pharmacy student.
Very well explained! Thank you so much
Thank you for taking an effort to make this video .
The overall video was great. I would just like to note that the Mechanism of Action for Fondaparinux is incorrect. Fondaparinux actually binds to Anti-thrombin III and potentiates its selectivity and affinity for Xa. Fondaparinux is in fact Anti-thrombin III mediated which is what distinguishes it from the direct Xa inhibitors (ApiXAban, EdoXAban. RivaroXAban and BetriXAban) which are not Anti-thrombin 3 mediated.
I love your videos! Please keep up the great work!
Thank you so much for making this topic understand in just 16 minutes :)
I am self studying some medical subjects without requisite chemistry and without other helpful pre medical information. Despite the brain damage I got from this, your lecture has really helped me understand the activity of aspirin in coagulation. Huge thanks for uploading this, it has been a great help to me 😎
Thank you for videos..you make me attention for this mechanism
Thank you a lot! This lecture is amazing!
bravo! I never understood these really till now!! thanks dude!!!!!!!!!!
Great video, it helped me a lot!
you are the best . the video is awesome you make me love pharmacology thanks & please continue
CONGRATULATION for this video, really easy to understand !!!
thank you very much for posting this video. you made this topic really easy and interesting.
Buddy ... You are making things damn easy ... Thanks for making such a informative video ... combining all three classes of medications was good idea...
Very clear , coherent and insightful
Exactly what I needed. Thanks
Thank you, Short and sufficient 👍🏼
All the important points are wonderfully covered with clear explanation 😍😍
You are totally genius man...thanks for your hard work...that make our understanding to pharmacology very easy..a billion thanks to your work
I am not a doctor or pharmacist but after watching this video I understand each and everything about clotting. bless you bro (Y) Thumbs up .
perfect lecture thank you very much
Thanks for this. It's well explained.
God bless ya speed pharmacology. You have cleared my goddamn concepts and eased my existential crisis of proffs.❤️ May God bestow you best rewards!
Beautiful explanation. Thank you!
Thank you sir for this video.. Excellent video 👌of totally information about all coagulation,anti coagulation,anti platelets,thrombolytic. Thanking you..
VERY HELPFUL!! thank you so much!!
thank you so much. the drawings really help me understand much more than powerpoint slides alone
thank you so much! life saving lecture!!
GREAT PRESENTATION .THANKS
Lots of helpful videos by speed pharmacology, thank u.
Such an amazing talk. Really made me understand this topic
Life Saving Pharmacology Tutorials!
Very clear and so so helpful! Thanks a lot! It has been long time it was not clear, but now it is, praise the Lord! :)
absolutely perfect, thank you so much
Thank You, Expert!!!!
exam tomorrow. Really help me understand more ! thank you !
Thank you..you saved my time
dude you just saved my life, thanks for the vid
Wow! You are gifted to teach.
Amazing! you made it easy for me
This is fantastic! More videos please!!
amazing explanation. you guys rock!
My mind was just blown 🤯🤯🤯 absolutely awesome video! I highly recommend! Very helpful 👌
Excellent presentation. Thank you.
Thank you for the brilliant lecture ☺️
Amazing explanation. Thank you very much
Best lecture ever, keep going sir!
One word speed learning pharmacology.. thank you sir..
Thanks.... Everything in one video
Great video! Thank you!
wonderful explaination!!!
what a great video . YOU ARE A SMART MAN .
Great explanation. Thank you
YOU ARE AWESOME! THANK YOU SO MUCH
thankz for your explanation, its so helpfull, cant wait your next video..
Perfect lecture for Anticoagulants and Antiplatelets
Thank you for your education.
These videos are literal lifesavers! If you can, could you add mnemonics too?
best pharmacology explanation ever!!!!
thank you so much , u just saved my life