Pharmacology - ANTICOAGULANTS & ANTIPLATELET DRUGS (MADE EASY)

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Anticoagulants, commonly referred to as blood thinners, are drugs that prevent or reduce coagulation of blood, prolonging the clotting time. Antiplatelet drugs, also known as a platelet aggregation inhibitors, decrease platelet aggregation and inhibit clot formation. These drugs play an important role in the treatment of various disorders such as myocardial infarction, thrombotic stroke and venous thromboembolism. This pharmacology lecture covers topics such as pathophysiology of blood clot formation and platelet function; activation, aggregation, cross-linking; ADP receptors, glycoprotein IIb/IIIa receptors, cyclooxygenase-1 (COX-1) enzyme, fibrinogen, fibrin mesh, coagulation cascade; intrinsic & extrinsic pathways, clotting factors, antithrombin, heparin induced thrombocytopenia, INR, plasmin, and plasminogen; mechanism of action of platelet inhibitors, anticoagulants, thrombolytic agents, and drugs used for treatment of bleeding. Drugs mentioned include; Aspirin, Clopidogrel, Ticagrelor, Ticlopidine, Prasugrel, Abciximab, Eptifibatide, Tirofiban, Heparin, low molecular weight heparins; Enoxaparin, Dalteparin, Protamine sulfate, Apixaban, Rivaroxaban, Univalent & Bivalent direct thrombin inhibitors; Argatroban, Dabigatran, Bivalirudin, Desirudin, Warfarin, Vitamin K, Alteplase, Reteplase, Tenecteplase, Urokinase, Streptokinase, Aminocaproic acid, Tranexamic acid.
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0:00 Platelet plug formation
2:04 Platelet aggregation inhibitors
5:34 Coagulation cascade
7:38 Anticoagulants
12:03 Warfarin
14:11 Thrombolytics

Пікірлер: 419

  • @SpeedPharmacology
    @SpeedPharmacology9 ай бұрын

    🚀 Elevate Your Pharm Game! 📚 Join Patreon for A+ Study Notes! 👉 www.patreon.com/speedpharmacology 👈

  • @Doctor____Z

    @Doctor____Z

    7 ай бұрын

    Perfect

  • @Samahn112
    @Samahn1125 жыл бұрын

    Update: an antidote for apixaban and rivaroxaban is now available: Andexanet alfa. Came out in 2018, one year after this video was uploaded.

  • @heiitsme182

    @heiitsme182

    3 жыл бұрын

    thank you for information

  • @Padmashrinaren

    @Padmashrinaren

    3 жыл бұрын

    Thanks 👍👍

  • @user-jk1ez3jf5d

    @user-jk1ez3jf5d

    2 жыл бұрын

    Thank you

  • @N4REG

    @N4REG

    2 жыл бұрын

    Also, Dabigatran has an antidote, Praxbind

  • @Ola-ox4bc

    @Ola-ox4bc

    Жыл бұрын

    Idarucizumab a monoclonal antibody

  • @alexnelson6196
    @alexnelson61964 жыл бұрын

    It's nice to have a diagram of the cascade and then interject each drug class where it acts. Thank you! This is how all topics should be taught by all teachers!

  • @sarahll5486
    @sarahll54862 жыл бұрын

    since i was pharmacy student i used to watch your videos before mid & final exams and it help me to remember things & make it easier now i'm officially graduated pharmacist but still love watching your videos😅 so i want to say thank u so much for making pharmacology easier on me ❤️🧸

  • @shuaibumansuryushau5921

    @shuaibumansuryushau5921

    11 ай бұрын

    From which country are you from Ma??

  • @Azharali-sk7yw

    @Azharali-sk7yw

    4 ай бұрын

    I'm doing my b.pharm 3rd year right now.. Is there any scope for pharmacy after graduation???? Because, I don't see any scope in India as they are paying very low for the pharmacists.

  • @anhduong8031
    @anhduong80314 жыл бұрын

    Please keep making those videos, it was organized, simple, and really straightforward. You just save my 5-hour listening to recording lectures. Thank you so much

  • @ganeshramakrishnan9455
    @ganeshramakrishnan94555 жыл бұрын

    this video is absolute gold. thank you so much for taking your time to make this, you deserve an award.

  • @xueyingzhu9430
    @xueyingzhu94303 жыл бұрын

    Coagulation cascade are the ones I found hardest at med school and it was a pain to revise when comes to finals then I forget about it. Now I'm preparing for core training exams and actually find this video more helpful than ever. I never understood this topic any clearer (I guess with more clinical experience it also helps to understand bit more). Thanks so much for making this video.

  • @roxana5490
    @roxana54905 жыл бұрын

    This was perfect from beginning to end. Information logically categorized, great talking speed, use of graphics that helped anchor understanding... bless you for taking the time to make this! First time seeing your videos, instantly subscribed. Looking forward to watching the rest of your videos through Pharmacology class!

  • @nishamanoj3099

    @nishamanoj3099

    4 жыл бұрын

    kzread.info/dash/bejne/q6Kisq-glKi8ZbA.html

  • @VV-lj7ns

    @VV-lj7ns

    2 жыл бұрын

    You are conveying little faster

  • @VV-lj7ns

    @VV-lj7ns

    2 жыл бұрын

    And your slang make it us difficulty in understanding in some places

  • @jessie7607
    @jessie76073 жыл бұрын

    I would just like to say thank you for captioning your content! As a subtitle person, you're making it easier for me to learn, so thank you.

  • @chiamakadorisanyaneji5405
    @chiamakadorisanyaneji54054 жыл бұрын

    Amazing video. I have been struggling with this topic but this has made it very easy for me . Thank you.

  • @belquees8796
    @belquees87965 жыл бұрын

    WHO KNEW IT WAS THIS EASY!!! I can't thank you even for saving my life

  • @bibisart4198
    @bibisart41985 жыл бұрын

    thanks for keeping your lectures short, simple and to the point

  • @raymond4884
    @raymond48842 жыл бұрын

    Great summary video! thanks for the post. It was very helpful. I like that you give examples of all the drugs in each class and their mechanisms with visuals. This helps to solidify the information for visual learners.

  • @sasori962008
    @sasori9620086 жыл бұрын

    I was struggling with this for hours then I found your video This is the freaking best!

  • @nishamanoj3099

    @nishamanoj3099

    4 жыл бұрын

    kzread.info/dash/bejne/q6Kisq-glKi8ZbA.html

  • @leongkeenwai6673
    @leongkeenwai66732 жыл бұрын

    Thank you for the great video! The reversal agents discovered after this video was made: for apixaban it’s andexanet alfa, and for dabigatran it’s idarucixumab.

  • @aakash8138
    @aakash81385 жыл бұрын

    Excellent video! Covers everything. Really grateful to you for making this!😀

  • @MusicforYoungViolinists
    @MusicforYoungViolinists6 жыл бұрын

    EXCELLENT - perfect for nursing students. Thanks for making this!

  • @DemonicAngelPhantomX
    @DemonicAngelPhantomX6 жыл бұрын

    you are literally a life saver!!! thank you so much for making my life and concepts easier. God bless you

  • @theglycoprotein3157
    @theglycoprotein31574 жыл бұрын

    I have just discovered you and u have no idea how grateful I am.

  • @maricruz4132
    @maricruz41325 жыл бұрын

    This was the best video for the Hemostasis drugs!! Thank you!!! Perfect!!!!

  • @twinklelight1362
    @twinklelight136211 ай бұрын

    The best lecture so far of this very complicated topics and the use of picture aids is just superb!❤

  • @elinamor4638
    @elinamor4638 Жыл бұрын

    Excellent video. Well organized, clear, and logically explained. Thank you!

  • @simon2023
    @simon20237 ай бұрын

    I am fortunate to find your channel and watch your lectures. They are directly oriented to the point and easy to understand. Thanks so much!!!!

  • @daliamuhmod7747
    @daliamuhmod77475 жыл бұрын

    you are an amazing person who make everything in pharmacology easier and simple (may god bless you )

  • @syriansongs
    @syriansongs6 жыл бұрын

    Man you’re the best... love your lectures~

  • @u.x8050
    @u.x80503 жыл бұрын

    Thank you so much! I can't believe I was struggling with them from 2 hrs and I got it at once or twice from a 16 min video.

  • @swashnaavneeta943
    @swashnaavneeta9437 жыл бұрын

    Oh my god! I was literally waiting for the upload of video on this topic. Sir, You make learning process in pharmacology so simple and easy to understand. I owe all my good marks to your lectures! Thanks a ton❤

  • @mmss4428

    @mmss4428

    6 жыл бұрын

    Avneeta Swashna

  • @noor.travels2
    @noor.travels25 жыл бұрын

    I can't thank you enough, God bless you, may you achieve more than what you wish for💕

  • @kenanironside3118
    @kenanironside3118Ай бұрын

    I watched the first video from your channel 6 years ago when i was in semester one 1 trynna understand autonomic NS drugs. and now I am doing my internship and wanted to revise. thank you for being with me throughout the journey

  • @Ak.shafi7104
    @Ak.shafi71049 ай бұрын

    I'm officially graduated pharmacist still love to watch ur videos , thanku so mch for making pharmacology easier

  • @eulllight5141
    @eulllight51416 жыл бұрын

    Thank you so much, so clear and simple May God bless you

  • @gosego.x
    @gosego.x2 жыл бұрын

    Brief but very educative! Thank you. God bless!

  • @RohitSingh-mv6xy
    @RohitSingh-mv6xy6 жыл бұрын

    Hi, Can you make video on Antiemetics.. And Thanks a lot for making the toughest topics of pharmacology EASIEST..!

  • @ctinoco1834
    @ctinoco18344 жыл бұрын

    Amazing video, pal! Thanks for making the difference in my study process!!!!

  • @attulurivenkatabadarinath1044
    @attulurivenkatabadarinath10445 жыл бұрын

    Well simplified... Great job.. Thank you.

  • @zacsofarjustfriends
    @zacsofarjustfriends4 жыл бұрын

    This video is incredible! So helpful! Thank you so much!!

  • @arinarakhteenko579
    @arinarakhteenko5795 жыл бұрын

    Thank you so much! So simple and amazing!

  • @drSJV
    @drSJV Жыл бұрын

    The best video of the topic! Thank you!

  • @TheTamanglakola
    @TheTamanglakola Жыл бұрын

    I loved this- straight to the point.

  • @mrcharlesjohnson
    @mrcharlesjohnson5 жыл бұрын

    Dude, this is awesome! Thnk you from a struggling pharmacy student.

  • @isabelcastaneda7439
    @isabelcastaneda74395 жыл бұрын

    Very well explained! Thank you so much

  • @madhangopal6117
    @madhangopal61176 жыл бұрын

    Thank you for taking an effort to make this video .

  • @Pacrac249
    @Pacrac2493 жыл бұрын

    The overall video was great. I would just like to note that the Mechanism of Action for Fondaparinux is incorrect. Fondaparinux actually binds to Anti-thrombin III and potentiates its selectivity and affinity for Xa. Fondaparinux is in fact Anti-thrombin III mediated which is what distinguishes it from the direct Xa inhibitors (ApiXAban, EdoXAban. RivaroXAban and BetriXAban) which are not Anti-thrombin 3 mediated.

  • @igj3224
    @igj32244 жыл бұрын

    I love your videos! Please keep up the great work!

  • @meghasa8416
    @meghasa84163 жыл бұрын

    Thank you so much for making this topic understand in just 16 minutes :)

  • @Dazzletoad
    @Dazzletoad5 жыл бұрын

    I am self studying some medical subjects without requisite chemistry and without other helpful pre medical information. Despite the brain damage I got from this, your lecture has really helped me understand the activity of aspirin in coagulation. Huge thanks for uploading this, it has been a great help to me 😎

  • @muhammadfadhli3120
    @muhammadfadhli31203 жыл бұрын

    Thank you for videos..you make me attention for this mechanism

  • @drquynhtandinh
    @drquynhtandinh4 жыл бұрын

    Thank you a lot! This lecture is amazing!

  • @squreshi8413
    @squreshi84135 жыл бұрын

    bravo! I never understood these really till now!! thanks dude!!!!!!!!!!

  • @haleysharp6876
    @haleysharp68765 жыл бұрын

    Great video, it helped me a lot!

  • @topwork5551
    @topwork55515 жыл бұрын

    you are the best . the video is awesome you make me love pharmacology thanks & please continue

  • @samuraiworkout9919
    @samuraiworkout99196 жыл бұрын

    CONGRATULATION for this video, really easy to understand !!!

  • @mounikachamarthi4315
    @mounikachamarthi43155 жыл бұрын

    thank you very much for posting this video. you made this topic really easy and interesting.

  • @Marufpatel
    @Marufpatel6 жыл бұрын

    Buddy ... You are making things damn easy ... Thanks for making such a informative video ... combining all three classes of medications was good idea...

  • @oofir900194
    @oofir9001943 жыл бұрын

    Very clear , coherent and insightful

  • @KaotooPholvivat
    @KaotooPholvivat3 жыл бұрын

    Exactly what I needed. Thanks

  • @Aqeelah8
    @Aqeelah82 жыл бұрын

    Thank you, Short and sufficient 👍🏼

  • @swathikona145
    @swathikona1454 жыл бұрын

    All the important points are wonderfully covered with clear explanation 😍😍

  • @joerobinson5950
    @joerobinson59506 жыл бұрын

    You are totally genius man...thanks for your hard work...that make our understanding to pharmacology very easy..a billion thanks to your work

  • @kashifrazamir
    @kashifrazamir4 жыл бұрын

    I am not a doctor or pharmacist but after watching this video I understand each and everything about clotting. bless you bro (Y) Thumbs up .

  • @alimajid3187
    @alimajid31877 жыл бұрын

    perfect lecture thank you very much

  • @noraniamacaumbos1542
    @noraniamacaumbos15426 жыл бұрын

    Thanks for this. It's well explained.

  • @fizzaali388
    @fizzaali3884 жыл бұрын

    God bless ya speed pharmacology. You have cleared my goddamn concepts and eased my existential crisis of proffs.❤️ May God bestow you best rewards!

  • @ireneudebuana
    @ireneudebuana2 жыл бұрын

    Beautiful explanation. Thank you!

  • @bhagyashreekanani3802
    @bhagyashreekanani38025 жыл бұрын

    Thank you sir for this video.. Excellent video 👌of totally information about all coagulation,anti coagulation,anti platelets,thrombolytic. Thanking you..

  • @simplybee4208
    @simplybee42085 жыл бұрын

    VERY HELPFUL!! thank you so much!!

  • @aliciayeung8486
    @aliciayeung84865 жыл бұрын

    thank you so much. the drawings really help me understand much more than powerpoint slides alone

  • @poichinteng9548
    @poichinteng95486 жыл бұрын

    thank you so much! life saving lecture!!

  • @khamikos1
    @khamikos16 жыл бұрын

    GREAT PRESENTATION .THANKS

  • @Ola-ox4bc
    @Ola-ox4bc Жыл бұрын

    Lots of helpful videos by speed pharmacology, thank u.

  • @dockalra
    @dockalra Жыл бұрын

    Such an amazing talk. Really made me understand this topic

  • @AquaDoll34
    @AquaDoll344 жыл бұрын

    Life Saving Pharmacology Tutorials!

  • @annafilipov8435
    @annafilipov84355 жыл бұрын

    Very clear and so so helpful! Thanks a lot! It has been long time it was not clear, but now it is, praise the Lord! :)

  • @thomasdarmawan7862
    @thomasdarmawan78622 жыл бұрын

    absolutely perfect, thank you so much

  • @suresh111100
    @suresh1111003 жыл бұрын

    Thank You, Expert!!!!

  • @frhneil1463
    @frhneil14632 жыл бұрын

    exam tomorrow. Really help me understand more ! thank you !

  • @user-jp1gt9ts2u
    @user-jp1gt9ts2u3 жыл бұрын

    Thank you..you saved my time

  • @sirfappiog
    @sirfappiog4 жыл бұрын

    dude you just saved my life, thanks for the vid

  • @The5375
    @The53754 жыл бұрын

    Wow! You are gifted to teach.

  • @umarmusa6204
    @umarmusa62046 жыл бұрын

    Amazing! you made it easy for me

  • @oxlopez
    @oxlopez5 жыл бұрын

    This is fantastic! More videos please!!

  • @zoeygozoom
    @zoeygozoom6 жыл бұрын

    amazing explanation. you guys rock!

  • @myqtran93
    @myqtran932 жыл бұрын

    My mind was just blown 🤯🤯🤯 absolutely awesome video! I highly recommend! Very helpful 👌

  • @lozserg1
    @lozserg1 Жыл бұрын

    Excellent presentation. Thank you.

  • @malikadnanoffical338
    @malikadnanoffical338 Жыл бұрын

    Thank you for the brilliant lecture ☺️

  • @sahanbasnayake1809
    @sahanbasnayake18094 жыл бұрын

    Amazing explanation. Thank you very much

  • @abubakarbarki8373
    @abubakarbarki83734 жыл бұрын

    Best lecture ever, keep going sir!

  • @iamrsk9145
    @iamrsk91456 жыл бұрын

    One word speed learning pharmacology.. thank you sir..

  • @dr.albekhan8640
    @dr.albekhan8640 Жыл бұрын

    Thanks.... Everything in one video

  • @lilizzym
    @lilizzym4 жыл бұрын

    Great video! Thank you!

  • @wajihanaz9393
    @wajihanaz93933 жыл бұрын

    wonderful explaination!!!

  • @hossamnasser7683
    @hossamnasser76835 жыл бұрын

    what a great video . YOU ARE A SMART MAN .

  • @ahmedkhalid5578
    @ahmedkhalid55789 ай бұрын

    Great explanation. Thank you

  • @JoeMich993
    @JoeMich9936 жыл бұрын

    YOU ARE AWESOME! THANK YOU SO MUCH

  • @gangsardamai8139
    @gangsardamai81392 жыл бұрын

    thankz for your explanation, its so helpfull, cant wait your next video..

  • @AjayM19065
    @AjayM190656 жыл бұрын

    Perfect lecture for Anticoagulants and Antiplatelets

  • @eclkt
    @eclkt4 жыл бұрын

    Thank you for your education.

  • @mananshah1306
    @mananshah13062 жыл бұрын

    These videos are literal lifesavers! If you can, could you add mnemonics too?

  • @prettykitty3285
    @prettykitty32852 жыл бұрын

    best pharmacology explanation ever!!!!

  • @fofa-xm1jo
    @fofa-xm1jo5 жыл бұрын

    thank you so much , u just saved my life