Endocrinology | Hypothalamus: Anterior Pituitary Connection

Official Ninja Nerd Website: ninjanerd.org
Ninja Nerds!
During this lecture we will be concluding our two part series on the hypothalamus pituitary connection. During this lecture, Professor Zach Murphy will be discussing the connection between the anterior pituitary gland and the hypothalamus, along with the hormones that are involved. We hope you enjoy this lecture and be sure to support us below!
References:
● Le T, Bhushan V, Sochat M, Chavda Y, Zureick A. First Aid for the USMLE Step 1 2018. New York, NY: McGraw-Hill Medical; 2017
● Marieb EN, Hoehn K. Anatomy & Physiology. Hoboken, NJ: Pearson; 2020.
● Boron WF, Boulpaep EL. Medical Physiology.; 2017.
● Jameson JL, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2). McGraw-Hill Education / Medical; 2018
● Hall JE, Hall ME. Guyton and Hall Textbook of Medical Physiology. Philadelphia, PA: Elsevier; 2021
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#ninjanerd #Hypothalamus #Endocrinology

Пікірлер: 170

  • @roronoazoro3204
    @roronoazoro3204 Жыл бұрын

    No one affected my life as much as Zach He has increased my productivity so much I’m so used to his explanation technique that today when my professor was explaining this subject he wasn’t explaining bad but I knew what I was missing which is an explanation which is not only reading slides and showing pictures but it’s drawing and explaining the drawing step by step then show me the whole picture that ease the remembering of what he has been explaining for me since the first minute unlike the slides which when the professor was explaining the third slide I had already forgotten what was explained in the first slide. Thank you thank you thank you zach❤

  • @hassaanharoon2140

    @hassaanharoon2140

    Жыл бұрын

    hope he can correct your sense of direction, Zoro....

  • @ScottMortensen1
    @ScottMortensen12 жыл бұрын

    What the actual F? I am very smart. So are my professors. This guy does laps around us all. He is a national treasure. No doubt, the best instructor I’ve ever had. Billion dollar Treasure this man right here.

  • @owoeyepaul8995

    @owoeyepaul8995

    2 жыл бұрын

    🤝International treasure

  • @namataswabrah8477

    @namataswabrah8477

    Жыл бұрын

    not just national but an international treasure...we love you and thanks alot

  • @idimogumarycynthia6930

    @idimogumarycynthia6930

    11 ай бұрын

    @@owoeyepaul8995 qqqq

  • @alexandraandronik7479
    @alexandraandronik7479 Жыл бұрын

    Please, don’t stop making these videos!!! You are king of teaching

  • @raenashaikh3377
    @raenashaikh33772 жыл бұрын

    Now that I have seen a couple of your videos, I can assert that you maintain a fantastic quality of information and teaching style in your lectures!!! Immensely helpful to everyone interested in human hormonal mechanisms. Thanks a lot for your efforts and sharing this video!

  • @IamAyOG
    @IamAyOG Жыл бұрын

    Got a test today and have been listening to these videos and it helps everything in between. My professor is super smart but you’re super smart and make it easier to understand. Great explanations and communication.

  • @user-rl5bi5lz5d
    @user-rl5bi5lz5d5 жыл бұрын

    Amazing you are really a thing ... thank u so much 🌸 I’m a medical student and ur videos always save me before exams

  • @vln1985
    @vln19853 жыл бұрын

    Amazing explanations... We are lucky to have these lectures on medical topics from an expert teacher like you..

  • @2YKSS2N
    @2YKSS2N4 ай бұрын

    thank you for sticking through the whole process of making this video

  • @jasec619
    @jasec6195 жыл бұрын

    I too am a medical student. Your videos single handedly got me an A on one of my tests

  • @AnitaCorbett
    @AnitaCorbett3 жыл бұрын

    Beautifully presented - clear - interesting- MEMORABLE 🥇✅ Thank you

  • @mosesnchimunya8136
    @mosesnchimunya8136 Жыл бұрын

    I can't compare you with my lecturers,you are a Ninja Nerd indeed,thanks alot.

  • @user-zu1dm2my4i
    @user-zu1dm2my4i Жыл бұрын

    You are a hero! The best teacher I have ever had (I am into my second master's degree in Nursing) and you are the best there is! THANK YOU!

  • @shairyjd
    @shairyjd Жыл бұрын

    I'm so glad I found this video. Really helps visualize and better understand the research paper I was reading about the HPA axis

  • @josetrujillo738
    @josetrujillo7383 жыл бұрын

    Thank You Zach! Thank You Rob and Kristen!

  • @irfanullah-uk3ks
    @irfanullah-uk3ks4 жыл бұрын

    I am proud of your hard effort for student.Amazing lectures Sir.

  • @paulinepainvin258
    @paulinepainvin258 Жыл бұрын

    you are a genius; Everything is so much clearer with you ! Please Never stop, you are the best med university 🤩

  • @echexgenny4058
    @echexgenny4058 Жыл бұрын

    Woow ,after a long time of hustling to understand hypothalamus,guy broke it down in just an hour.i appreciate @ ninja nerds great work really🎉🎉🎉🎉🎉🎉

  • @Mssclark
    @Mssclark3 жыл бұрын

    You have a gift. Thank you for this sir🙏🏽

  • @DrHosam24
    @DrHosam243 жыл бұрын

    I love your amazing videos. My diploma should say graduated from Ninja Nerd University! A small suggestion that would make this perfect is adding captions. I and most my friends like to listen to your videos at 1.5x or 2x speed and it's great but some of the names become difficult to make out. Another reason is me having a photographic memory so seeing the word in captions makes it stick. Keep up the good work! You're helping countless students not die of stress!

  • @owoeyepaul8995

    @owoeyepaul8995

    2 жыл бұрын

    Looking forward to NINJA NERD UNIVERSITY

  • @tarikn.g.dabbous3323

    @tarikn.g.dabbous3323

    Жыл бұрын

    That's correct. Ninja Nerd University >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> med schools out there. lol

  • @HCEI
    @HCEI2 жыл бұрын

    This is really good! I have just seen this today and I'm impressed.💯

  • @sarahsdeal
    @sarahsdeal6 жыл бұрын

    what do you do? these videos are incredible!!! holding my hand through school!

  • @NinjaNerdOfficial

    @NinjaNerdOfficial

    6 жыл бұрын

    +Sarah H. We are so happy to hear that Sarah! Keep on studying and tell your class mates!

  • @drjerry1492
    @drjerry14925 жыл бұрын

    Easy, To the point & interesting lecture...Thanku soo much sir .. God bless u 👍

  • @dr.notsostrange9449
    @dr.notsostrange94493 жыл бұрын

    Love your lectures !! Thank you sooo much

  • @ydelge1614
    @ydelge16144 жыл бұрын

    You are amazing!!! Thank you so much; make med school so much easier🙌❤

  • @sacchrine_
    @sacchrine_4 жыл бұрын

    Isa kang alamat! Love from Philippines ❤

  • @vaishnavigolwala9860
    @vaishnavigolwala98606 жыл бұрын

    Really the incredible videos this are... Thnk u so much for teaching in such a wonderful manner... This really makes all the concepts crystal clear.. Thnk u really a lot. .

  • @Salvietem
    @Salvietem3 жыл бұрын

    this is my favorite youtube channel ❤ ❤

  • @mohammadyaqoob7576
    @mohammadyaqoob75764 жыл бұрын

    U have stimulated my whole endocrine system with ur lectures U r amazing Myself an anesthesiologist.. R u a doctor???

  • @nazneensyed100

    @nazneensyed100

    3 жыл бұрын

    Me student of anesthesia

  • @Nina-mz7cq
    @Nina-mz7cq4 ай бұрын

    Your videos help me so much studying physiology ! I got 8.9/10 at my first partial, hoping to do as good or better for the second one !

  • @dennishead7290
    @dennishead72903 жыл бұрын

    Spectacular!

  • @georgepaul6240
    @georgepaul62404 жыл бұрын

    Excellent video

  • @user-oe9nc9ex1w
    @user-oe9nc9ex1w3 жыл бұрын

    you are really helpful, thank you !!!!!!

  • @user-kf9qs8ls3b
    @user-kf9qs8ls3b Жыл бұрын

    فدوة لربك ع هذا الشرح

  • @riyanbabar8416
    @riyanbabar841611 ай бұрын

    Phenomenal lecture 👌

  • @armina.a
    @armina.a3 ай бұрын

    Thank you so much! you are the best ❤ BTW those neurons are sooo funny and cute!❤

  • @bhawnasharma7635
    @bhawnasharma76353 жыл бұрын

    During breast feeding, prolactin secretion is increased......so breast feeding and estrogen should inhibit the release of PIH...right?? Then the sign must be negative By the way.....great explanation sir...lots of love and respect from India

  • @nikolaognjenovic743

    @nikolaognjenovic743

    2 жыл бұрын

    Thats what I thought too

  • @JokermanMaria

    @JokermanMaria

    2 жыл бұрын

    I think he meant that breastfeeding, estrogen leveles, birth controls leveles are stimulating the production of prolactin.You are right, there should be a negative sign on the effect of dopamine secretion

  • @thejoyofstudying5408

    @thejoyofstudying5408

    Жыл бұрын

    yeah zach was talking about prolactin so yeah the sign should be negative

  • @learn2789
    @learn27893 жыл бұрын

    Amazing , thank u so much boss 🌹❤️

  • @ruling_2844
    @ruling_28444 ай бұрын

    I wanna be say thankss a lot to you. I am a vet student so ı have limited sources and my profs cannot tell the lecture cleary . Their slides is so confucing source so because of this that uni life is like a hell to me before ı met your chanel . Thanks a lottt ❤ videos are about more human medicine but some basics is same . That part is enough to me for a beginner or maybe intermadiate level to this major.

  • @niazwali8169
    @niazwali81694 жыл бұрын

    amazing sir g ur the best medical teacher and Dr we creates more subscriber for u sir

  • @rozhinarazavian8392
    @rozhinarazavian8392 Жыл бұрын

    The part that you muted the original sound and put your voice again on video was kinda interesting. Thank you for your videos. You make this world a bit better. :)

  • @muneerbhaiyat9777
    @muneerbhaiyat97776 жыл бұрын

    Do you have a video on positive and negative feedback?

  • @codrut913
    @codrut9134 жыл бұрын

    YOU are best bro !!!!

  • @pragatigupta8094
    @pragatigupta80943 жыл бұрын

    Amazing way of explanation...love from India🇮🇳

  • @yashaswanipatwa99

    @yashaswanipatwa99

    3 жыл бұрын

    Which college??

  • @jemimahcansancio1249
    @jemimahcansancio12494 жыл бұрын

    Hello may i ask what references you use for your lectures?

  • @amryosry4910
    @amryosry49104 жыл бұрын

    excellant!

  • @learningdesire9740
    @learningdesire97403 жыл бұрын

    Thank you sir ❤

  • @mananchawda
    @mananchawda4 жыл бұрын

    great video ...

  • @troybonner91
    @troybonner913 жыл бұрын

    11:20 "Thought we wouldn't notice. But we did." - Tony Stark Great video! You're helping me ace my A&P classes, sir.

  • @kameliasali9639

    @kameliasali9639

    3 жыл бұрын

    I thought that something was wrong with my laptop lol

  • @victoriagoetz9002
    @victoriagoetz90022 жыл бұрын

    awesome thanks ninja nerd

  • @simasarevic823
    @simasarevic8236 жыл бұрын

    Dude when Zach starts talking about the inhibiting versions of hypothalamic hormones, the sound of the video doesn't match the visual. But a couple of seconds later it's fixed.

  • @harshitapandit206

    @harshitapandit206

    4 жыл бұрын

    lol thanks for this comment,i thought im having some kind of visual error! XD

  • @zahraaalani3890
    @zahraaalani3890 Жыл бұрын

    Zach should be put in a museum

  • @ayushibhardwaj7929
    @ayushibhardwaj79293 жыл бұрын

    Thank you🤗 very nice lecture you cleared my concept on NPO Only suggestion plz give us time to take screenshot at the end

  • @suzanagjidiaj1470
    @suzanagjidiaj14702 жыл бұрын

    Why does the preoptic nucleus look like Madam Hooch, the flying instructor at Hogwarts 😭

  • @mr.epinephrine6845

    @mr.epinephrine6845

    8 ай бұрын

    😂

  • @Docera-wu9ow

    @Docera-wu9ow

    28 күн бұрын

    😂😂😂

  • @hamdlaraib6221
    @hamdlaraib62213 жыл бұрын

    Wonderful

  • @wicterwterr4245
    @wicterwterr42453 жыл бұрын

    Boom! Another topic on finger tips.

  • @pelmanyabocho2947
    @pelmanyabocho2947 Жыл бұрын

    Thank youu

  • @ciaralama
    @ciaralama3 жыл бұрын

    Very effective lecture.....love from Nepal,🇳🇵🇳🇵🇳🇵🇳🇵

  • @zainaziz1269

    @zainaziz1269

    3 жыл бұрын

    Love from Pakistan

  • @aashishchaudhary4620
    @aashishchaudhary46203 жыл бұрын

    GnRH IS Released by preoptic nucleus or arcuate nucleus.. i found on one book that it is released by arcuate nucleus.. i get confused please clarify me sir?

  • @2YKSS2N
    @2YKSS2N4 ай бұрын

    you are the best

  • @usamakhan5679
    @usamakhan56793 жыл бұрын

    Thanks, sir

  • @adilmajeed5256
    @adilmajeed52565 жыл бұрын

    Is there any role of supraoptic nucleus in the stimulation of TRH

  • @rowlandwickramathilaka2516
    @rowlandwickramathilaka25163 жыл бұрын

    love from sri lanka !!!!!!!!

  • @josetrujillo738
    @josetrujillo7382 жыл бұрын

    Sweet Deal!

  • @hashimshaban2367
    @hashimshaban2367 Жыл бұрын

    U r a science wizard 🙌💕🙏💥✨👑💫 doctor

  • @gesund6275
    @gesund62753 жыл бұрын

    Thanks for the video, but you didn´t mention what stimulates the GnRH Cheers

  • @alaaelshiekh4516
    @alaaelshiekh45162 жыл бұрын

    Thanx man

  • @jshtaway1
    @jshtaway13 жыл бұрын

    Can you please give us a screen of the finished white board so we can screenshot what we've learned to help us remember!!!

  • @tonystarkim9288
    @tonystarkim92888 ай бұрын

    thanks sir

  • @DoctorMera
    @DoctorMera2 жыл бұрын

    Subhan Allah ❤️🥰 So beautiful 💚💚😇

  • @abdiwelimohamedali3164
    @abdiwelimohamedali31643 жыл бұрын

    Awesome

  • @ViolaMaster
    @ViolaMaster3 жыл бұрын

    There is a typo @14:45, breastfeeding inhibits Dopamine release because Dopamine inhibits Prolactin, otherwise great video, thanks!

  • @t4_2g

    @t4_2g

    Жыл бұрын

    What about estrogen and bc pills?

  • @ViolaMaster

    @ViolaMaster

    Жыл бұрын

    @@t4_2g Estrogen will stimulate the Anterior Pituitary to release prolactin for breastfeeding. However, once it reaches so high, the prolactin will actually inhibit GNRH from releasing FSH and LH, essentially negative feedback. This explains why it's harder (but not impossible!) to become pregnant again while breastfeeding d/t anovulation. As for OCPs, it depends on the type and concentration of estrogen/progesterone/progestin.

  • @honeybellebuzlucay5867

    @honeybellebuzlucay5867

    Жыл бұрын

    I was thinking the same, thank you!

  • @ViolaMaster

    @ViolaMaster

    Жыл бұрын

    @@honeybellebuzlucay5867 no problem! 🙂

  • @niazwali8169
    @niazwali81694 жыл бұрын

    but i have a question to ask sir what other activities do u do especially in hospital

  • @manarosman452
    @manarosman4523 жыл бұрын

    thank u sourabh

  • @Mission-Omega.
    @Mission-Omega.3 жыл бұрын

    TnQ sir♥

  • @elenagisellebarajasrojas1233
    @elenagisellebarajasrojas1233 Жыл бұрын

    i loveee your videos, thank you so much. I have one question, isn't somatostatin secreted in the paraventricular nucleus? 🤔

  • @ahmedhussainijs
    @ahmedhussainijs3 жыл бұрын

    where there are inhibitory versions of each hormone, shouldn't there also be a releasing version of Prolactin inhibitory hormone(dopamine?)

  • @DaveBuikema
    @DaveBuikema6 жыл бұрын

    Wouldn't breastfeeding, high estrogen levels, and birth control pills, all inhibit PIH release?

  • @ahmadarabiat4333

    @ahmadarabiat4333

    5 жыл бұрын

    Dave Buikema right ?!?! I checked that 1000 times 😓😓😓

  • @med8615

    @med8615

    5 жыл бұрын

    right?

  • @edilbertoramos3045

    @edilbertoramos3045

    5 жыл бұрын

    If PIH is inhibited prolactin is produced w/c is necessary for milk production. Therefore, breastfeeding can inhibit PIH because breastfeeding promotes prolactin release. Estrogen & Combined Birth Control Pills can inhibit milk production. Which means they can trigger PIH.

  • @thefenerbahcesk4156

    @thefenerbahcesk4156

    4 жыл бұрын

    @@edilbertoramos3045 Estrogen inhibits milk production? Also if their breastfeeding, wouldn't they need more milk (not less)?

  • @saroabd4437

    @saroabd4437

    4 жыл бұрын

    He said they can influence PIH. That means either inhibit or stimulate.

  • @ranipatidar353
    @ranipatidar3532 жыл бұрын

    Sir is gonadotropin releasing harmone relase from pre optic nucleus or arcuate nucleus?

  • @naierafathy9102
    @naierafathy91023 жыл бұрын

    Alright, we're moving 5:58 ❤❤❤

  • @akshayraj2920
    @akshayraj29204 жыл бұрын

    Love From INDIA

  • @lakshmankumar1263
    @lakshmankumar12633 жыл бұрын

    In your previous video u said its arcuate which does releasing factors and inhibitory factors and now u turn to pvn

  • @ayoungperson3408
    @ayoungperson34085 жыл бұрын

    Genesis is to music what you are to Physiology simply supreme

  • @colmkelly8978
    @colmkelly89785 жыл бұрын

    I think the analysis at the end may be misleading at 15:05 , you said breastfeeding increases PIH which isn’t a secondary stimulus

  • @DannyJay-dz7xj

    @DannyJay-dz7xj

    3 жыл бұрын

    i was thinking the same thing, thank you for pointing that out!

  • @fakihaahsan4699
    @fakihaahsan46994 жыл бұрын

    amazingggggggggg

  • @93shreelakshmihs

    @93shreelakshmihs

    4 жыл бұрын

    🥳😍

  • @syedrizwan960
    @syedrizwan9603 жыл бұрын

    Please can you do other physiology lectures like on GIT and brain and netvouse system please please

  • @ibrahimabdullah1133
    @ibrahimabdullah11335 жыл бұрын

    Is there a prolactin releasing hormone??!

  • @drumarhayatofficial1735
    @drumarhayatofficial17354 жыл бұрын

    Sir you don't mention anterior nucleus in supra optic reagion.

  • @hamzehyacoub8575
    @hamzehyacoub85753 жыл бұрын

    Hi! thank you.. how can breast feeding stimulate Dopamine which decreases milk?! you wrote it has a + feedback on PIH (Dopamine)

  • @SanyuAEWhite

    @SanyuAEWhite

    3 жыл бұрын

    So, take my words with a grain of salt, but I believe what he was saying is that normal levels of Dopamine inhibit the lactotropes. So normally, there is a low level of prolactin in the body. BUT, when there is a low level of dopamine, the lacotropes are no longer being inhibited, and so they produce higher levels of prolactin. Which I believe is why women commonly experience the "baby blues" at around day 4 or 5 of thier baby's life, because this is when the thick, fatty, colostrum transitions into white breastmilk. Breastfeeding and nipple stimulation also increases the production of Oxytocin, the "cuddle hormone" or bonding hormone.

  • @chaimaa4303
    @chaimaa4303 Жыл бұрын

    greatyttt

  • @kekhrievorsuohu1827
    @kekhrievorsuohu18273 жыл бұрын

    We have Jr Najeeb here 👍👍👍

  • @yasminali7578
    @yasminali75786 жыл бұрын

    I’m a little confused, this video is second in the playlist series.... but It seems like you’re continuing off from another video. So this can’t be the second video in your endocrinology playlist series. Can you link me the previous video of where you seem to be continuing off from?

  • @NinjaNerdOfficial

    @NinjaNerdOfficial

    6 жыл бұрын

    +Yasmin Ali hypothalamus-posterior pituitary connection

  • @NinjaNerdOfficial

    @NinjaNerdOfficial

    6 жыл бұрын

    kzread.info/dash/bejne/Y2etqdl9cdnIgaw.html It is in the correct order now, thanks

  • @yasminali7578

    @yasminali7578

    6 жыл бұрын

    Ninja Nerd Science thanks so much!

  • @ettubashirtaiwo6206

    @ettubashirtaiwo6206

    Ай бұрын

    Yes, there's a video on posterior pituitary gland before this.

  • @TheUlumpa
    @TheUlumpa3 жыл бұрын

    Anterior pituitary #1

  • @caitlynnichols3632
    @caitlynnichols36326 жыл бұрын

    What is the difference between the follicle stimulating hormone and the luteinizing hormone?

  • @NinjaNerdOfficial

    @NinjaNerdOfficial

    6 жыл бұрын

    +Caitlyn Nichols hello! Check out our video on the ovarian cycle in the reproductive playlist.

  • @caitlynnichols3632

    @caitlynnichols3632

    6 жыл бұрын

    thank you :)

  • @404sdn
    @404sdn Жыл бұрын

    Can we get the notes of this topic sir…?

  • @sajateacher
    @sajateacher3 жыл бұрын

    You can tell how old I am when I hear "What does GNRH stand for?" and I immediately think, "Guns 'N' Roses Hormone"...

  • @AnilKumar-tc4ne
    @AnilKumar-tc4ne2 жыл бұрын

    ❤️❤️❤️

  • @musakhanmedicalenginee890
    @musakhanmedicalenginee8908 ай бұрын

    Thanks sir ,buy i have question,, I'm confused, anterior pituitary gland have different types of cells? because you(sir) say this specific signal which come from hypothalamus to stimulate that specific type of cell ,to secret that specific Harmon

  • @lukasschopf374

    @lukasschopf374

    2 ай бұрын

    Yes, in the anterior pituitary, there are different cell types that produce the respective hormones and also have receptors to respond to corresponding releasing and inhibiting hormones: - Somatotrophs produce and secrete growth hormone (GH). - Lactotrophs produce and secrete prolactin (PRL). - Thyrotrophs produce and secrete thyroid-stimulating hormone (TSH). - Corticotrophs produce and secrete adrenocorticotropic hormone (ACTH).

  • @kashish8761
    @kashish87612 жыл бұрын

    ❤️❤️

  • @nyile012
    @nyile0126 жыл бұрын

    GHRH and somatostatin is released by ventromedial nucleus no?? and Arcuate nucleus releases prolactin inhibiting factor or dopamine???

  • @ibrahimabdullah1133

    @ibrahimabdullah1133

    5 жыл бұрын

    prolactin inhibiting hormone is dopamine

  • @sorayaaskari9171
    @sorayaaskari91715 жыл бұрын