Drug delivery by Magnetic Induction Heating | Drug DOX release from Magnetic hydrogel Nanoparticles
Magnetic Field Responsive DOX Drug Release from Magnetic polymer coated Fe304 iron oxide Nanoparticles by Magnetic Induction Heating. Induction heating, hypertherima treatment.
Magnetic nanoparticles (MNPs) generate heat when a high-frequency magnetic field (HFMF) is applied to them. Induction heat is useful not only for hyperthermia treatment but also as a driving force for drug-release. In this study, we synthesized, characterized and biologically tested multifunctional Fe3O4-based drug delivery systems for such an application. The nanosystems were successfully prepared with a small size, high saturation magnetization and high drug loading. The Fe3O4 core in an alternating magnetic field could generate enough heat for both effective hyperthermia therapy and doxorubicin release from the alginate shell for chemotherapy. Also, a folate factor was attached to the nanoparticles to help the system to enter and stay in the tumor cells for a longer time.
Пікірлер: 11
Hello, you may say the percentage of each of the materials used. Or introduce the related article.
@polymerscope6881
2 жыл бұрын
U can read here; title " Synthesis of Magnetic Field Sensitive poly(AAm-co-VSA)-PVA/Fe3O4 Nanospheres and Investigation of Their Drug Release Behaviors Under AMF" , URL = dergipark.org.tr/en/pub/ejosat/article/898018, DOI NUMBER: doi.org/10.31590/ejosat.898018
Hiii, thanks for the demostration, could you say me if the white material in the coil is to thermal isolation?
@polymerscope6881
2 жыл бұрын
Yes, it surrounds the copper coil for thermal insulation.
Could you mention the frequency of your induction heater and the size of MNPs
@polymerscope6881
2 жыл бұрын
320 kHz, MNP size about 50 nm, Polymer coated MNP abaout 220 nm.
@littlebit7695
2 жыл бұрын
@@polymerscope6881 thanks
What is this all about, I don't get it
@polymerscope6881
2 жыл бұрын
This method can be used in controlly drug delivery systems and hyperthermia in medicine for locally treatment.
Sir, can I know the voltage and frequency of induction heater?
@polymerscope6881
2 жыл бұрын
320 kHz, 4mT, 5 Amper