Dr. Volek & Dr. Phinney - Translating the Basic Science of Nutritional Ketosis & Keto-Adaptation

Ғылым және технология

Filmed at the Emerging Science of Carbohydrate Restriction and Nutritional Ketosis, Scientific Sessions at The Ohio State University
Learn more at blog.virtahealth.com/category...
An impressive body of scientific evidence over the last 15 years documents long term benefits of carbohydrate-restricted, especially ketogenic, diets. We now understand molecular mechanisms and why they work. Popular books and articles now challenge the advice ‘carbohydrates are good and fats are bad.’ Circa mid-19th century urinary ketones were identified in diabetics sealing their toxic label for the next 150 years. Despite work four decades ago showing ketones were highly functional metabolites, they are still misidentified as toxic byproducts of fat metabolism. The vilification of fat by regulatory and popular dogma perpetuates this myth. But the nutrition-metabolic landscape is improving dramatically.
A growing number of researchers have contributed to what is now a critical mass of science that provides compelling clinical evidence that ketogenic diets uniquely benefit weight loss, pre-diabetes, and type-2 diabetes. In the last five years, basic scientists have discovered that b-hydroxybutyrate (BHB), the primary circulating ketone, is a potent signaling molecule that decreases inflammation and oxidative stress. BHB has been suggested to be a longevity metabolite, with strong support from recently published mouse studies showing decreased midlife mortality and extended longevity and healthspan. Although type-2 diabetes is often described as a chronic progressive disease, emerging evidence indicates that sustained nutritional ketosis can reverses the disease. There is growing interest in studying potential therapeutic effects of ketosis on cardiovascular diseases, cancer, and neurodegenerative diseases including Alzheimer’s and Parkinson’s. There are even reasons certain athletes may benefit from nutritional ketosis and ketone supplements ─ debunking the long-standing dogma that high carbohydrate intake is required to perform optimally.
With the support of the well-established Ohio State Food Innovation Center, this conference will bring together the top experts in these fields to share what has been achieved and what remains to be done to advance this exciting field of scientific discovery.

Пікірлер: 64

  • @ldean8360
    @ldean83605 жыл бұрын

    I lost not only 57 lbs, but also skin disorders, neuropathy, asthma, GERD and high blood pressure. ****** I just got back from my eye doctor. My retina has healed cotton wool spots and damaged blood vessels (in the last year) that had been present for multiple years prior. ***** I know I sound like a total snake oil salesman but there is no way around it. I can barely believe it myself. And I'm not even that strict on the keto; my ketones are 0.4 most of the time and I cycle in and out of ketosis often (I eat a lot of fruit and carrots). I also can't be sure my results are due entirely to the keto diet because I also do intermittent fasting as well. What I can say for sure is that I have never seen this kind of health response to a "diet" before and I've tried countless variations of high carb/low fat diets. So, in summary, I'm on the fence with dietary ketosis but I'm fully on board with low carb, high natural fats and intermittent fasting. I have multiple, well documented, measurements that prove that, for my body, a low carb diet, coupled with fasting, exercise and weight loss can heal degenerative disease.

  • 5 жыл бұрын

    👍👍👍

  • @russellbrooks23able

    @russellbrooks23able

    5 жыл бұрын

    I lost 65 pounds and a list of 23 health issues reversed. No snake oil; carb and junk food restrictions, whole food eating only, with intermittent and extended fasting.

  • @davidgroth26

    @davidgroth26

    5 жыл бұрын

    Congratulations L Dean. I hope you are very proud of yourself, not many people will do what you do.

  • @bytejuggler

    @bytejuggler

    5 жыл бұрын

    Last time I had an eye test I had a similar experience. My optician also was slightly surprised as my eyesight had an fact modestly improved. I'm astigmatic and additionally in my 40's at the point where often near eyesight also starts deteriorating, she was slightly surprised that there's no sign of this and that in fact my eyesight had improved. This correlates with me starting a ketogenic diet now some 2 years ago. (Additionally people have commented that I appear younger than I actually am. My skin and face is a lot more youthful than it was several years ago.)

  • @therockstar17

    @therockstar17

    5 жыл бұрын

    Ketosis is not a magical condition it's just a label given to how much ketogenesis happening in your body and how many ketones are in your blood. It's just your body's natural way of using fat for fuel in the absence of eating carbohydrate, so if you're on board with low carb, you should automatically be on board with ketosis! You have to get your energy from either carbs or fat so if you're not getting it from carbs then you you're going to be in ketosis at some point especially if you're doing intermittent fasting, otherwise you'd starve!

  • @donaldreitsma6419
    @donaldreitsma64195 жыл бұрын

    Followed Dr's Volek and Phinney since I started. I suggest reading their book "The Art & Science of Carbohydrate Living: An expert guide to making the life-saving benefits of carbohydrate restriction sustainable and enjoyable."

  • @JulianaSzabluk
    @JulianaSzabluk5 жыл бұрын

    Thank you, Virta. Your work is critical to our work. Keep on the good, serious research. Thanks once again.

  • @intermittentfastingandketo8457
    @intermittentfastingandketo84575 жыл бұрын

    Thanks Virta for posting. We need more of this information getting out there!

  • @kayeszymanski6945
    @kayeszymanski69455 жыл бұрын

    Wonderful video!! Very informative. Thanks Dr. Phinney and Dr. Volek! 👏🏻👏🏻👏🏻

  • @akanecortich8197
    @akanecortich81975 жыл бұрын

    If you sweat a lot, exercise or get dehydrated - check you potassium. I ended up in hypoKalemia due to this on the keto diet. Now I add a potassium salt to my cooking.

  • @staceykersting705

    @staceykersting705

    4 жыл бұрын

    7-10 cups of veg per day.

  • @RalphTGP

    @RalphTGP

    4 жыл бұрын

    Potassium bicarbonate, Magnesium malate, D3 (an essential hormone), C with fat, Thorne B, DHA. Try that for a few weeks.

  • @simonsaunders4881

    @simonsaunders4881

    4 жыл бұрын

    also follow Jeff's advice and drink 3 cups of bone broth youll get 3 grams of potassium a day, i really think this was our common way of potassium absorption in our ancient past, it is so odd this mineral is soo high.

  • @Julia-xf5ps
    @Julia-xf5ps5 жыл бұрын

    Wonderful presentation. Thank you.

  • @hope46sf
    @hope46sf5 жыл бұрын

    Such helpful information!! Thank you!

  • @CTC84
    @CTC844 жыл бұрын

    I love keto. Its been a consistent for ten years. But I cannot stay in ketosis for longer than a few weeks or I become almost manic. Meaning I am soo high energy and so efficient that I don't sleep for more than a few hours a night and I feel very wired. This is why I began intermittent keto. 7-10 days, cheat and repeat.

  • @levellwheeler8157
    @levellwheeler81575 жыл бұрын

    Very well explained and good use of charts

  • @berndgolz9000
    @berndgolz90005 жыл бұрын

    great talk - thank you

  • @danmauney8394
    @danmauney83944 жыл бұрын

    Great video and information!

  • @motomatta1
    @motomatta14 жыл бұрын

    Excellent podcast 🙂👍

  • @ResidualSelfImage
    @ResidualSelfImage3 жыл бұрын

    Moving to a ketogenic diet (KD) is a significant jump from the standard American diet - time restricted eating/intermittent fasting (TRE/IF) can help control hunger and advance satiety sensitivity which is important for Type 2 Diabetics (T2D). The use of healthy fats and avoidance of carbohydrates/sugars in a ketogenic diet can advance satiety and limit caloric intake/glycemic load.... electrolyte mineral nutrient monitoring (EMNM) is the most important risk factor in fasting and in the ketogenic diet. The ketogenic diet is more difficult to support in *food deserts in North America* . Shifting a T2D metabolism with a KD takes time but can be accelerated when used with TRE/IF but requires EMNM to prevent the risk of refeeding syndrome.

  • @theromanempire12
    @theromanempire125 жыл бұрын

    wow!

  • @carolspooner7798
    @carolspooner77985 жыл бұрын

    Why do we burn fat at 2x the level on keto diet compared to carby diet? Is there a video or article someplace that explains the science/biochemistry/mechanism for why this happens?

  • @VirtaHealth

    @VirtaHealth

    5 жыл бұрын

    Once the body is keto adapted, you become efficient at using fat as your primary fuel. This post explains how adaptation works: blog.virtahealth.com/ketone-ketosis-basics/

  • @runemartinguldberg9056
    @runemartinguldberg90563 жыл бұрын

    I miss John Yudkin, Joseph Fraft and Gerald Reaven on this golden age list...

  • @johnmiller5259
    @johnmiller52595 жыл бұрын

    👍☺️

  • @Jefferdaughter
    @Jefferdaughter4 жыл бұрын

    22:21 - 'There is some carbohydate in protein foods. When an animal is slauhtered there is glycogen in the muscle.' At the 5-10 grams per day Phinney estimates, this is negligable. However, it is my understanding that the glycogen in the muscle meat of animals is quickly converted to lactic acid. Does anyone out there have info or references on this?? Most muscle meats were traditionally hung in a cool location for awhile before being consumed. Beef that has been aged for a month or longer is a hot 'new', but really old, trend. Organ meats, on the other hand, are best fresh. Or frozen immediately after the animal is harvested.

  • @beefling5390
    @beefling53903 жыл бұрын

    7:00

  • @martinirving3824
    @martinirving38245 жыл бұрын

    "Panoply."

  • @skp2073
    @skp20735 жыл бұрын

    Dr. Gundry claims a Keto Diet is not recommended for those carrying the APOE4 allelle(s) - has anyone studied this?

  • @VirtaHealth

    @VirtaHealth

    5 жыл бұрын

    Hi Sherri, thanks for your question. The human research data on this are spare at best. Dr. Gundry is a cardiothoracic surgeon who has published papers and books about the risks of plant-based lectins and coronary heart disease, but he has published no peer-reviewed research on the topic of ketogenic diets. Based upon this review of the literature, his views on the interaction between the ApoE4 allele and nutritional ketosis should be viewed as a hypothesis until proven otherwise.

  • @HybridParentSupport
    @HybridParentSupport4 ай бұрын

    1:50

  • @Discovery_and_Change
    @Discovery_and_Change4 жыл бұрын

    9:40 if I'm already in ketosis from a low carb diet, does that mean I shouldn't intermittent fast so as not to reach "starvation ketosis" ?

  • @jonathandiaz962

    @jonathandiaz962

    3 жыл бұрын

    i don't know if this answers your question, but my Public health professor intermittent fasts and follows a keto diet with daily exercise and he has done great :) he swears by it!!

  • @yvandaniel8050

    @yvandaniel8050

    3 жыл бұрын

    for diabetic people in crisis, "starvation ketosis" is usually associated with high glucose levels. That is not the case for healthy persons since the glucose is low. High ketones might render the blood/body slightly more acidic. Vegetables and/or carbonated water can compensate for that. So, there is no danger associated with high ketones if glucose is low: www.virtahealth.com/blog/ketone-ketosis-basics

  • @rharnevious
    @rharnevious2 жыл бұрын

    "Well formulated" hmmm

  • @maikanoibrahim5565
    @maikanoibrahim55652 жыл бұрын

    The day I came across Dr IGUDIA KZread channel was the day I started living a more comfortable life again after using his herbs medication in curing my Diabetes disease

  • @ld9044
    @ld90445 жыл бұрын

    How is the "normal " person supposed to know exactly how many calories they burn per day?

  • @ldean8360

    @ldean8360

    5 жыл бұрын

    I have a fitbit as a first approximation, but my best strategy is to weigh myself every day. If I'm out of my 3 pound window I make an adjustment. Using this method I never have more than 2-3 pounds to deal with. (I recently lost 57 lbs, so I have first hand experience with obesity and pre-diabetes). Maintaining weight is much harder than losing weight. On a keto diet losing weight is basically a no brainer. In my opinion the main benefit of a keto diet is that it facilitates fasting. Fasting was key to my weight loss. I am older and my system has been seriously damaged by the conventional nutritional advice of the past 40 years. I may never be able to eat the "normal" three meals per day no matter what the composition. This is not so bad as it seems. I spend far less time dealing with food. That's time I'm not cooking, cleaning dishes etc....

  • @donaldreitsma6419

    @donaldreitsma6419

    5 жыл бұрын

    That's a good question and if anyone thinks they know then they don't understand metabolism, because it vares. Having said that, it is not about counting calories. Keep carbohydrates at 20g or less per day, 1 - 1.5g of protein per kg of lean mass ( used you target weight) and then eat enough fat to be full. DON'T COUNT CALORIES!

  • @donaldreitsma6419

    @donaldreitsma6419

    5 жыл бұрын

    @@ldean8360 I appreciate what you are saying and congrats!! I have Fitpants and Fitring. I don't weigh myself very often. Close to you, I lost 50 lbs and had all the metabolic syndrome markers which are now gone. I am now up and down around 45 lbs less because that's where my body wants to be. I don't worry about a weight window because I maintain a fairly consistent diet and eat to satiety so trust my body to know what's right for it. If I gain or lose a few lbs (some days it is up to 4 lbs a day!) it is probably due to water and the tell tale sign is how tight my wedding ring fits (because I did test against weight and seems to be a correlation). I mainly go by how my pants fit. LOL!

  • @yoso585

    @yoso585

    5 жыл бұрын

    Donald Reitsma The only reliable and truly relevant measurement is that of the waist.

  • @dana102083

    @dana102083

    5 жыл бұрын

    @@ldean8360 your salt intake can change drastically day to day's weight.. Or if you have cycled in carbs at maintenance. I cn influence 5.lbs alone woth salt amd ive gaimed 8 lbs overnight from a carbup. Amd again lost 2 lbs per day. I just wanted to mention that. Im 7 month at maintenance amd i found it important to have other goals to focus on. I keep a 5 lb variance in my cycle. Cheers! :)

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