Diabetes Insipidus and SIADH | Clinical Medicine

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Ninja Nerds!
In this lecture, Professor Zach Murphy will present on Diabetes Insipidus (DI) and the Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH). We will discuss the pathophysiology of DI, which involves a deficiency of antidiuretic hormone (ADH) leading to excessive urine production, and SIADH, which involves excessive ADH leading to water retention and hyponatremia. The lecture will include a discussion on the clinical manifestations of DI, such as polyuria and polydipsia, and SIADH, such as fluid overload without edema and dilutional hyponatremia. The digital presentation will begin with the diagnostic approach, highlighting the importance of water deprivation tests for DI, serum, and urine osmolality measurements, and serum sodium levels. Finally, we will review management strategies for both conditions, emphasizing fluid intake adjustments and desmopressin for DI, and fluid restriction, salt tablets, or medications to block ADH effects in SIADH. Please support us below!
Table of Contents:
0:00 Lab
0:07 Diabetes Insipidus & SIADH Introduction
0:44 Pathophysiology of Diabetes Insipidus
4:29 Central Diabetes Insipidus
8:58 Nephrogenic Diabetes Insipidus
12:55 Pathophysiology of SIADH
20:41 Complications of Diabetes Insipidus
26:16 Complications of SIADH
32:51 Diagnostic Approach to Diabetes Insipidus
36:00 Diagnostic Approach to SIADH
38:14 Treatment of Diabetes Insipidus
39:24 Treatment of SIADH
45:05 Comment, Like, SUBSCRIBE!
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#ninjanerd #endocrine #diabetesinsipidus

Пікірлер: 34

  • @abdiwelihassan5310
    @abdiwelihassan53103 ай бұрын

    I was worried you might be gone from this channel forever. But I kept the faith. Welcome back, man. 🙏

  • @samra6840
    @samra68403 ай бұрын

    I love the diagnostic algorithm part at the end. It really helps with consolidating the information. 🙌

  • @abbygonzalez8518
    @abbygonzalez85182 ай бұрын

    Thank you so much! you made this topic so easy and understandable!!! THE BEST!!!

  • @valviv
    @valviv3 ай бұрын

    Great video, thanks Ninja Nerd!

  • @camilasalcedo9469
    @camilasalcedo94693 ай бұрын

    ur carrying my entire MD on ur gd back... my tuition should go to u, my guy

  • @spectre-24J
    @spectre-24J21 күн бұрын

    great video as always, thank you very much!

  • @sonamdhondup5426
    @sonamdhondup5426Ай бұрын

    INCREDIBLE TEACHER!

  • @31dharachhatrara62
    @31dharachhatrara623 ай бұрын

    Beautifully explained with crystal clear concepts , Thank you so much sir 😊, your videos are very informative and helpful to us ..😊

  • @user-ug8wd2no5s
    @user-ug8wd2no5sАй бұрын

    Thank you alot for this effort ❤

  • @user-ri8fg9er5u
    @user-ri8fg9er5uАй бұрын

    Love this guy so much ❤️❤️❤️❤️❤️🤌🏼🤌🏼🤌🏼🤌🏼🤌🏼🤌🏼

  • @narjesalbazi7190
    @narjesalbazi7190Ай бұрын

    Thank you so much ☺️

  • @fatmamohamedasefi1604
    @fatmamohamedasefi160413 күн бұрын

    Thank you so mutch

  • @reignlulubell
    @reignlulubellАй бұрын

    Thank you for your video. I learned a lot even though, I'm student nurse.

  • @bovanovsky
    @bovanovsky15 күн бұрын

    Sir. You're my hero

  • @saraabuhusein7278
    @saraabuhusein72782 ай бұрын

    thank you❤️❤️

  • @alifakih3840
    @alifakih3840Ай бұрын

    Great video

  • @Conspii_Donald
    @Conspii_Donald2 ай бұрын

    Why are Thiazide diuretics used for treating nephrogenic DI although they promote diuresis...?🤔

  • @NinjaNerdOfficial

    @NinjaNerdOfficial

    2 ай бұрын

    Great question - they lead to mild hypovolemia which activates the RAAS which leads to enhanced sodium and water reabsorption in the PCT which leads to less polyuria. Although it seems paradoxical it does seem to be effective in nephrogenic DI

  • @Conspii_Donald

    @Conspii_Donald

    2 ай бұрын

    @@NinjaNerdOfficial Thanks boss...🙏

  • @FEATHERMAN11485
    @FEATHERMAN114853 ай бұрын

    I want to shake your hand in person after getting this Medical degree!

  • @Maryaamn
    @MaryaamnАй бұрын

    Thanks ❤

  • @excuseme1139
    @excuseme11393 ай бұрын

    could you get renal failure in DI?

  • @pietropanza8247
    @pietropanza82472 ай бұрын

    So osmotic demyelination syndrome can occur both in an acute and chronic hyponatremia due to SIADH?

  • @sofiaespinosamorales109
    @sofiaespinosamorales1093 ай бұрын

    TE AMO

  • @karthikamahalaxmi6681
    @karthikamahalaxmi6681Ай бұрын

    If u teach like that am not able to understand Love from India 🇮🇳🇮🇳

  • @priyadharshinis4562
    @priyadharshinis45622 ай бұрын

    BMP= Basic Metabolic Panel

  • @sanjith1179
    @sanjith11793 ай бұрын

    I st like sir, I'm pratheesh from india( tamilnadu).big fan of you sir.say one hii sir.

  • @3moory-rr2wx

    @3moory-rr2wx

    3 ай бұрын

    hi

  • @arijitkundu2263
    @arijitkundu226311 сағат бұрын

    Can we take a moment and appreciate how jacked he is , I mean , being and awesome teacher Anand a jacked man , oooh damn

  • @nijabudeenmohammedn5354
    @nijabudeenmohammedn53542 ай бұрын

    how to cure this disease cdi?

  • @syedmaroofshah5603
    @syedmaroofshah56033 ай бұрын

    ❤❤❤

  • @sarahahmad4147
    @sarahahmad41472 ай бұрын

    ❤❤❤❤

  • @karthikamahalaxmi6681
    @karthikamahalaxmi6681Ай бұрын

    Sir u can't u explain diagnostic evaluation and treatment on board y u started this new trend of teaching in computer plz stop this

  • @user-bu9mk5hd1y
    @user-bu9mk5hd1y2 ай бұрын

    💯🥷💯🥷💯🥷💯