Adrenal Insufficiency | Clinical Medicine

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Ninja Nerds!
In this lecture, Professor Zach Murphy will present on Adrenal Insufficiency. We will discuss the pathophysiology, including the inadequate production of adrenal hormones such as cortisol and aldosterone, which can be due to primary adrenal failure (Addison's disease) or secondary causes affecting the pituitary. The lecture will include a discussion on the clinical manifestations, such as fatigue, muscle weakness, weight loss, and electrolyte imbalances. The digital presentation will begin with the diagnostic approach, highlighting the importance of serum cortisol levels, ACTH stimulation tests, and imaging studies to assess adrenal and pituitary glands. Finally, we will review management strategies for Adrenal Insufficiency, emphasizing hormone replacement therapy to restore hormone levels and manage symptoms. Enjoy the lecture and support us below!
Table of Contents:
0:00 Lab
0:07 Adrenal Insufficiency Introduction
0:52 Primary Adrenal Insufficiency
3:56 Adrenal Cortex Injury
12:55 Secondary Adrenal Insufficiency
15:53 Hypopituitarism
20:38 Pituitary Suppression
23:27 Classic Findings of Adrenal Insufficiency
35:52 Complications of Adrenal Insufficiency
44:26 Diagnostic Approach to Adrenal Insufficiency
47:49 Treatment of Adrenal Insufficiency
51:11 Comment, Like, SUBSCRIBE!
Retired Ninja Nerd Lectures:
• Adrenal Insufficiency ...
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#ninjanerd #endocrine #adrenalinsufficiency

Пікірлер: 58

  • @abdelrahmanmetwally8976
    @abdelrahmanmetwally89763 ай бұрын

    Wait a minute, you apologised a few days ago for this masterpiece???!!! You smashed medicine , you monster ❤️❤️🔥🔥🔥🔥🔥💪💪💪💪💪

  • @DannyRusso
    @DannyRusso4 күн бұрын

    Explicação maravilhosa! E muito obrigada por acrescentar legendas em português! ❤️

  • @julelaynecurry6714
    @julelaynecurry6714Ай бұрын

    Thank you SOOO much for all your hard work in putting together these videos. Your clinical medicine series videos have been by far the most helpful resource for me for studying for Step 2. We love you!!!

  • @chrisso_o897
    @chrisso_o8973 ай бұрын

    literally the best teacher

  • @Mav2208
    @Mav2208Ай бұрын

    Amazing lecture as always. Ty Zach!

  • @valviv
    @valviv3 ай бұрын

    Great video, thanks Ninja Nerd!

  • @bonesaw7
    @bonesaw73 ай бұрын

    Excellent work as always

  • @ashleyelisabeth6479
    @ashleyelisabeth64798 күн бұрын

    I have Addison's Disease and love that you covered this !

  • @WedGirl23
    @WedGirl232 ай бұрын

    You are AMAZING!! Thank you so much!!

  • @BeverlyAtienoOkeyo
    @BeverlyAtienoOkeyo2 ай бұрын

    I love your teaching methodologies.

  • @arjunsunil2527
    @arjunsunil25273 ай бұрын

    Thank you for the videos

  • @nathaliacunha8386
    @nathaliacunha83863 ай бұрын

    PERFECT. PERFECTION.

  • @mari.4018
    @mari.40182 ай бұрын

    Thank you for this video

  • @miahaller1730
    @miahaller17303 ай бұрын

    your videos carry me through my advanced physiology class!

  • @jamshidimomov1740
    @jamshidimomov174029 күн бұрын

    Thank you Zach!

  • @shahiramohammadi7284
    @shahiramohammadi72843 ай бұрын

    Best teacher in the world ❤❤❤

  • @lewvonos1485
    @lewvonos148526 күн бұрын

    Thank You for wonderful lessons!

  • @justinenewman
    @justinenewman3 ай бұрын

    Outdone yourself with this one 👏🏻

  • @Think_Up
    @Think_Up2 ай бұрын

    Our kids asthma specialist had us put a humidifier inside their room which we later learned contributed to mold and dust mite growth, making their asthma chronic. He also prescribed FLOVENT, a steroid inhaler at a dose 4x what it should be for our tiny daughter and it shut down her adrenal system, she nearly died in ICU before an endocrinologist figured out the cause and treatment (cortisone helped her recover over 6 months until she was ok again). This doctor should be behind bars, but he's out doing it to thousands of other kids with the full support and profit of pharma. This system is not helping us. We got our kids off of the inhalers, removed the humidifier and they've been fine since. I'm not diagnosing other's conditions or situations but I'm a parent who nearly lost my child due to gross misuse of these drugs on my daughter.

  • @sneakypress

    @sneakypress

    Ай бұрын

    Please do not stop spreading your message . It’s relevant in all areas of health and medicine .

  • @mewmannamwem6087

    @mewmannamwem6087

    27 күн бұрын

    Hope she gets well soon ! get the papers and sue them !! you will save hundreds of lives

  • @pontesaludablepontefitpont8606
    @pontesaludablepontefitpont860614 күн бұрын

    You are great. Thank you for sharing yor knowledge.

  • @med-dr4yt
    @med-dr4yt3 ай бұрын

    Thank you very much

  • @japneetkaur1782
    @japneetkaur1782Ай бұрын

    Thankyou sooo much for this

  • @ARefinedMe
    @ARefinedMeАй бұрын

    I have secondary adrenal insufficiency, caused by Pembrolizumab (Keytruda) immunotherapy. I see several new people every week joining the support groups online who have this side effect of immunotherapy, I think it’s becoming more and more common. I have almost no cortisol, almost no acth, and almost no DHEA. I also have almost no estrone, estradiol, estriol, progesterone, or pregnenolone. I have high FSH and FH. I was not in menopause prior to chemotherapy & immunotherapy.

  • @robertmarking817
    @robertmarking817Ай бұрын

    Wow!!! Agreed this is a masterpiece presentation!!!👏😊

  • @Msrra7usam
    @Msrra7usamАй бұрын

    Thank you 💗

  • @muniruddinsk8078
    @muniruddinsk80782 ай бұрын

    U r amazing teacher .. love and respect 🙏🙏❤️

  • @kaitchou3405
    @kaitchou34053 ай бұрын

    Excellent

  • @mk-ek8pv
    @mk-ek8pv3 ай бұрын

    thank you!

  • @demure6055
    @demure605524 күн бұрын

    Thank you!

  • @ManikanthaGaddadevaramat-mu6ii
    @ManikanthaGaddadevaramat-mu6ii2 ай бұрын

    Excellency at its best❤

  • @user-ri6cg3sf3m
    @user-ri6cg3sf3m6 күн бұрын

    Thank you very much ❤

  • @Roxxy523
    @Roxxy5232 ай бұрын

    Sounds like your explanation fits some dysautonomia/ pots syndrome symptoms

  • @iliyaghiyasvand
    @iliyaghiyasvand3 ай бұрын

    You are amazing❤️

  • @s_b2346
    @s_b23463 ай бұрын

    From Yemen, big thanks

  • @narjesalbazi7190
    @narjesalbazi7190Ай бұрын

    Thanks

  • @yahyaabdullahi7625
    @yahyaabdullahi76252 ай бұрын

    You are amazing

  • @milosforman5221
    @milosforman52213 ай бұрын

    Awesome

  • @ahmedaskari881
    @ahmedaskari881Ай бұрын

    Love u zackk❤❤

  • @peachy19968
    @peachy199682 ай бұрын

    You rock

  • @HakimGanya
    @HakimGanya2 ай бұрын

    da best

  • @WilyStankCoyote
    @WilyStankCoyote8 күн бұрын

    Are there any other microbes that infect and deteriorate the adrenals? Never-ending. You answered.

  • @ivaldohadi886
    @ivaldohadi886Ай бұрын

    zach explain it like drinking water

  • @lasurfette7830
    @lasurfette783025 күн бұрын

    Why do I maintain a normal blood sugar when untreated for SAI if cortisol causes blood sugar to rise and my cortisol tanked?

  • @Katie-vy5rd
    @Katie-vy5rdАй бұрын

    Eosinophilia? Why would that be the case? And how high?

  • @WilyStankCoyote
    @WilyStankCoyote8 күн бұрын

    How can my mother have Secondary and a tumor and I also have Secondary (looking for a tumor)? Is this genetic? I have been in Addison crisis. If I can tell you guys it is AWFUL for the patient... Multiply awful x 1,000,000. INTENSE headache, vomiting, more intense headache, lots of urination, drink water, urinate it back out... Then, you just want to lie down and go to sleep. Luckily (I didn't know I had Addisons), I called a friend and told him I was dying. I didn´t know I was dying but it felt like dying. They called 9'11. You should know that intense crying and greiving sends me into Addisons Crisis. I don´t know if this is true for other patients. I was out of the country. I am very surprised the abulance knew to give me steroids.

  • @shi5702
    @shi5702Ай бұрын

    I have an upcoming SOAP note on anadrenal crisis case, without you my ass is grass 😭

  • @kaboom3908
    @kaboom390821 күн бұрын

  • @mandarinofracito1821
    @mandarinofracito18219 күн бұрын

    Yo I ❤

  • @user-ug9sb6hg3q
    @user-ug9sb6hg3q2 ай бұрын

    🎉🎉🎉🎉

  • @bootatoboo
    @bootatoboo2 ай бұрын

    why isnt CAH considered primary adrenal insufficiency?

  • @unsaiftikhar8580

    @unsaiftikhar8580

    Ай бұрын

    CEA is because of congenital absence of 21OH and manifested in young children.....

  • @unsaiftikhar8580

    @unsaiftikhar8580

    Ай бұрын

    CAH*

  • @abhishekkaushal5267

    @abhishekkaushal5267

    24 күн бұрын

    In CAH there is deficiency of 21-OH enzyme which cause decrease in aldosterone and cortisol and switch the pathway more towards the synthesis of androgen

  • @sanjith1179
    @sanjith11793 ай бұрын

    6 th like sir, I'm pratheesh from india ( Tamil Nadu).am big fan of you sir.say one hi sir.

  • @user-bu9mk5hd1y
    @user-bu9mk5hd1y3 ай бұрын

    💯🥷💯🥷💯🥷💯

  • @ahlam-yu1kk
    @ahlam-yu1kk6 күн бұрын

    You are AMAZING!! Thank you so much!!