Clearance and Rate of Elimination - Pharmacokinetics - Pharmacology Lect 12
This lecture covers clearance and rate of elimination. View the other videos on pharmacology below.
(1) Pharmacokinetics & ADME: • Pharmacokinetics for S...
DRUG ABSORPTION Videos:
(2) Drug Absorption Overview: • Absorption of Drugs - ...
(3) Bioavailability: • Drug Bioavailability O...
DRUG DISTRIBUTION Videos:
(4) Drug Distribution Overview: • Distribution - Pharmac...
(5) Volume of Distribution: • Volume of Distribution...
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DRUG METABOLISM Videos:
(6) First Pass Metabolism: • First Pass Metabolism ...
(7) Phase I Metabolism: • Phase I Metabolism - P...
(8) Phase II Metabolism: • Phase II Metabolism - ...
(9) First Order and Zero Order Kinetics: • First Order & Zero Ord...
(10) Drug Half-life: • Drug Half-life | An Ov...
(11) First-order elimination rate constant and half-life-details: • First Order Eliminatio...
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DRUG ELIMINATION / EXCRETION
(12) Drug Clearance: • Clearance and Rate of ...
(13) Renal Excretion of Drugs: • Renal Excretion of Dru...
(14) Ion Trapping: [not yet posted]
(15) Dosage Regimens: [not yet posted]
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Factors That Affect Drug Metabolism:
(16) Enzyme Induction: • Enzyme Induction - Pha...
(17) Competitive Inhibition Overview: • Competitive Inhibition...
(18) Competitive Inhibition of Statins: • Competitive Inhibition...
(19) Acetaminophen toxicity (Clinical Correlate): [Not yet posted]
(20) Pharmacogenomics Overview: • Pharmacogenomics | Asi...
(21) Slow Acetylators - Pharmacogenomics: [not yet posted]
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Пікірлер: 36
Wow, I just discovered your channel now and I'm surprised how I didn't come across it earlier. Thank you so much for the videos, all of them are extremely helpful. Please keep making more.
I'd like to thank you for doing these videos. They are helping me so much. I've had a hard time trying to understand the concepts in my textbook but now it's ALOT clearer!!!!!
" I want to be clear here " ... haha ! what a perfect line for the video.
Thank you so much for this video! It was so clear and I’m grateful for all the effort you’ve put in. It helped me a lot :)
Thank you soo much for posting this. It makes so much more sense.
Thanks for these videos, really helpful. Please keeping producing new videos
Hello, thanks so much for the videos, I love them. I have one question though. Is the elimination rate constant the same as the rate of elimination in this video? How are the 2 related? Really confused.
really great job explaining these concepts, thanks
Thank you so much for the videos!! :)
What happens with CL when we are in 0 order kinetics? When you look at the graph, CL is constant at 1st (green slope or 1st order kinectics). But does the CL go to zero when we're in 0 order kinetics? When I think of it logically, it doesn't make sense. Our bodies won't stop filtering just because we've maxed out our kidney's capacity... right? Someone help!
Thank you, thank you, thank you!
I really loved your lectures - my request is I could found anything amongst your lectures, which would cover subjects regarding - Achieving Steady State, Therapeutic window, Plateau Principle, Rate of infusion and Effect of loading dose as a logic continuation of drug elimination part of Pharmacokinetics. Anyway, thanks much, keep it going, bright clear lectures! Well Done.
Thank you for your efforts :)
Fantastic video!!!!!
Wonderful teaching. Thanks a lot. Can you please tell Which soft ware are you using to make teaching videos like this. Hiw do you make it
Many Thanks, was waiting it
Amazing!
This is great! Btw what book do you use?
From an Italian medical student: THANK YOU
awesome!
Does hepatic metabolism not play a role in drug clearance?
According to goodman gilmans " clearance is the volume of plasma cleared of drugs per min per kg of body" so unit will be ml/min/kg. But u are saying it is ml/min.....im confused now
cant thank you enough
u r awesome...
Thank you!!!!
Thank you
Plus what is CL in zero order kinetics??? N how half life affects CL???
Thank u so much
thanks
great
Plz upload more 😞
why havnt i discover this before
The "no pun intended" at 7:38 cracked me up
14999 thankful ppls :)
👏🏻👌🏻👍🏼
Thank you soo much for posting this. It makes so much more sense