Cerebrospinal fluid - function, production and circulation - animation by Dr. Cal Shipley, M.D.

Ғылым және технология

Review of cerebrospinal function, production and circulation in the human brain. NEU082
Related videos: trialimage.com/neurology-anim...

Пікірлер: 203

  • @svgs14
    @svgs149 жыл бұрын

    Sir, you summarised my one hour lecture into five minutes.Great.Respect.Thanks a ton !

  • @TrialImageInc

    @TrialImageInc

    9 жыл бұрын

    Glad it helped!

  • @baseeratfatima4246

    @baseeratfatima4246

    7 жыл бұрын

    same here bro

  • @raginald7mars408

    @raginald7mars408

    5 жыл бұрын

    I add 2 tons more

  • @danielpa8644
    @danielpa86442 жыл бұрын

    So far I watched 4 videos on CSF production, circulation, function and still I felt lost. This video gave me a "gut" understanding so I am sure I won't forget x years. Brilliant explanation.

  • @TrialImageInc

    @TrialImageInc

    2 жыл бұрын

    Thank you Daniel! You can access my entire library of medical videos at trialimage.com

  • @jbaketkd
    @jbaketkd8 жыл бұрын

    The best video representation of this process I have seen yet. Perfect explanation!

  • @TrialImageInc

    @TrialImageInc

    8 жыл бұрын

    Thanks Jacob!. You can access my entire library at www.CalShipleyMD.com

  • @ahmedayesh3728
    @ahmedayesh37282 жыл бұрын

    thanks a lot, you summarized the topic of CSF so perfectly and the video is so obvious

  • @amyburks858
    @amyburks8589 жыл бұрын

    This was immensely informative. I thank you for making this video which was intended to be supplementary but ended up giving more information than was given in lecture. Thank you again.

  • @TrialImageInc

    @TrialImageInc

    9 жыл бұрын

    I'm glad it helped Amy. You can find much more at my website www.calshipleymd. com

  • @joanvictoriacanete5817
    @joanvictoriacanete58178 жыл бұрын

    Best animation I've seen so far in here. Thank You!!

  • @TrialImageInc

    @TrialImageInc

    8 жыл бұрын

    Thanks Joan! Http://www.CalShipleyMD.com

  • @joeamrine7450
    @joeamrine74504 жыл бұрын

    This was the video I was looking for... this is the one video on KZread that shows a labeled csf moving throughout the anatomy... thank you for creating the one video on KZread to do so

  • @TrialImageInc

    @TrialImageInc

    4 жыл бұрын

    You are very welcome Joe. You can access my entire medical library at www.CalShipleyMD.com

  • @user-fr9op9zb5j
    @user-fr9op9zb5j3 жыл бұрын

    Simple,easy & representative Great job👏👏👏👏

  • @oliveabroad4278
    @oliveabroad42785 жыл бұрын

    This was a very clear, concise description of CSF and helped me to understand what I'm learning in class - thanks!

  • @TrialImageInc

    @TrialImageInc

    5 жыл бұрын

    Glad it helped Olive! You can access my entire library of Medical Videos at www.CalShipleyMD.com

  • @saharafsheen6964
    @saharafsheen69647 жыл бұрын

    best way to convey this topic

  • @javierchile88
    @javierchile888 жыл бұрын

    Incredible video. Now I can easily explain it to people. Your website is also easily accessible and very informative. I'll def suggest people there! Thanks.

  • @TrialImageInc

    @TrialImageInc

    8 жыл бұрын

    +Javier Palacios -thanks Javier! Access my entire library at CalShipleyMD.com

  • @Muuip
    @Muuip3 жыл бұрын

    Excellent concise visual presentation! Very informative, much appreciated! 👍

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Thank you Muuip! You can access my entire library of medical videos at trialimage.com

  • @goncalosilva9324
    @goncalosilva93244 ай бұрын

    Thank you for your video, it really helped me understanding this.

  • @sdas127
    @sdas1276 жыл бұрын

    Thanks for providing such an great informative video. Great illustration.

  • @TrialImageInc

    @TrialImageInc

    6 жыл бұрын

    +sdas127 - you re welcome! www.CalShipleyMD.com

  • @rmt3589
    @rmt35893 жыл бұрын

    Sweet! This is just the insight I needed to make my friend a functional CSF system!

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Thanks rmt! You can access my entire library of medical videos at trialimage.com

  • @teclajeptui9288
    @teclajeptui92889 ай бұрын

    Very clear and understandable. Thank you so much.

  • @ashish143b
    @ashish143b9 жыл бұрын

    it was great.....it made my most concepts clear...thanks Cal Shipley,MD

  • @TrialImageInc

    @TrialImageInc

    9 жыл бұрын

    Thanks Ashish! www.CalShipleyMD.com

  • @successneedstime96
    @successneedstime968 жыл бұрын

    Simply Marvelous !!!!

  • @TrialImageInc

    @TrialImageInc

    8 жыл бұрын

    Glad you liked it Zack! www.CalShipleyMD.com

  • @Leon-tq2dd
    @Leon-tq2dd8 жыл бұрын

    Beautiful visualization. Thank you, Dr. Shipley.

  • @TrialImageInc

    @TrialImageInc

    8 жыл бұрын

    +Leon Orenstein thank you! Http://www.CalShipleyMD.com

  • @TrialImageInc

    @TrialImageInc

    8 жыл бұрын

    +Leon Orenstein thank you! Http://www.CalShipleyMD.com

  • @heatherbaldwin8888
    @heatherbaldwin88887 жыл бұрын

    This is great! My Med/Surg nursing class does not go this in depth (with the villi and such), but going "deeper" helps me understand the material better. Thank you!

  • @TrialImageInc

    @TrialImageInc

    7 жыл бұрын

    +Heather Baldwin - thanks Heather! Good luck with your studies... www.calshipleymd.com

  • @sphoorti190
    @sphoorti1902 жыл бұрын

    Amazing and to the point video. Thank you sir.

  • @TrialImageInc

    @TrialImageInc

    2 жыл бұрын

    Thank you Sphoorti! You can access all of my medically related videos at trialimage.com

  • @HadeerSinawe
    @HadeerSinawe9 жыл бұрын

    Wonderful animation and explanation. Thanks!

  • @TrialImageInc

    @TrialImageInc

    9 жыл бұрын

    Glad it helped Hadeer. You can access my entire library of medical presentations at www.calshipleymd.com

  • @noraabdualwahab2283
    @noraabdualwahab22835 жыл бұрын

    Thank you for existing in life

  • @TrialImageInc

    @TrialImageInc

    5 жыл бұрын

    Thank you Nora! Www.CalShipleyMD.com

  • @Dgehjeo
    @Dgehjeo6 жыл бұрын

    Amazing. Thank you for sharing.

  • @TrialImageInc

    @TrialImageInc

    6 жыл бұрын

    My pleasure Fatima! You can access my entire library at www.CalShipleyMD.com

  • @Kaguro1
    @Kaguro18 жыл бұрын

    Thank you for this video and your website! The multimedia in there is very helpful for studying :D

  • @TrialImageInc

    @TrialImageInc

    8 жыл бұрын

    +Kaguro1 I'm glad it helped - access my entire video library www.calshipleymd.com

  • @user-zh7gv2zm5y
    @user-zh7gv2zm5y Жыл бұрын

    Thank you again

  • @ggonsg
    @ggonsg8 жыл бұрын

    LOVE your video. I'm studying to be a Craniosacral Therapist, so your video is sooooo helpful!!! Thank you!!!

  • @TrialImageInc

    @TrialImageInc

    8 жыл бұрын

    +Sharon Gonzales - that's great Sharon! You can access my entire video library at CalShipleyMD.com

  • @ggonsg

    @ggonsg

    8 жыл бұрын

    OOOOOOOOH; how very EXCITING. Thank you so much. I will check out your wonderful videos!!!! Yay!!!

  • @lawyerdoctor
    @lawyerdoctor5 жыл бұрын

    Thank you, that was very concise and intelligent.

  • @TrialImageInc

    @TrialImageInc

    5 жыл бұрын

    Thank you TK! You can view my entire medical video library at www.CalShipleyMD.com

  • @mafirris
    @mafirris8 жыл бұрын

    Thanks! Your video is so helpful !!

  • @TrialImageInc

    @TrialImageInc

    8 жыл бұрын

    +Mafe Ariza - I'm glad it helped, Mafe! Http://www.CalShipleymd.com

  • @paulafrengul9761
    @paulafrengul97617 жыл бұрын

    Very clear and well explained. Thank you.

  • @TrialImageInc

    @TrialImageInc

    7 жыл бұрын

    +Paula Frengul - thank you Paula! CalShipleyMD.com

  • @kashedaa.bonner-bey4295
    @kashedaa.bonner-bey42954 жыл бұрын

    Great explanation! Thanks!

  • @TrialImageInc

    @TrialImageInc

    4 жыл бұрын

    My pleasure Ka’Sheda - you can access my entire library of medical videos at: www.CalShipleyMD.com

  • @anitag2944
    @anitag2944 Жыл бұрын

    thank you so much for this video my lecturer did such a bad job at explaining the production and route of the csf

  • @Jessica-jq7lr
    @Jessica-jq7lr20 күн бұрын

    Thank you for this video! If CSF comes from the filteration of the plasma, how do you explain how organoids that are not vascularised, still can produce CSF?

  • @rayane565
    @rayane5652 жыл бұрын

    Thank you

  • @sakshis7277
    @sakshis72774 жыл бұрын

    Thank you :)... best video

  • @TrialImageInc

    @TrialImageInc

    4 жыл бұрын

    Thanks Sakshi! Https://trialimage.com

  • @helicart
    @helicart5 жыл бұрын

    Brilliant and to the point. Thanks for your efforts. I am a clinician with an interest in hydrocephalus pathophysiology, and this is a brilliant educational tool for the more enthusiastic patient.

  • @helicart

    @helicart

    5 жыл бұрын

    p.s. would be good to include CSF flow through glymphatics,.

  • @TrialImageInc

    @TrialImageInc

    5 жыл бұрын

    Many thanks helicart! Where do you practice?

  • @helicart

    @helicart

    5 жыл бұрын

    @@TrialImageInc Brisbane, Australia

  • @TrialImageInc

    @TrialImageInc

    5 жыл бұрын

    Nice part of the world! We hope to visit someday. Https://www.CalShipleyMD.com

  • @samirseginy5851
    @samirseginy58518 жыл бұрын

    Excellent !!

  • @TrialImageInc

    @TrialImageInc

    8 жыл бұрын

    +Samir Seginy - thanks Samir - you can access my entire library of medical presentations at www.calshipleymd.com

  • @nyawirawaithaka4993
    @nyawirawaithaka49935 жыл бұрын

    Thank you! Thank you! Thank you!

  • @TrialImageInc

    @TrialImageInc

    5 жыл бұрын

    You are most welcome Nyawira! Https://www.CalShipleyMD.com

  • @reem4912
    @reem49124 жыл бұрын

    Amazing. Thank you so much.

  • @TrialImageInc

    @TrialImageInc

    4 жыл бұрын

    Glad you liked it Reem www.calshipleymd.com

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Thanks Reem! You can access my entire library of medical videos at trialimage.com

  • @arielshikoba1857
    @arielshikoba18572 жыл бұрын

    Finally!!! A clear explanation! 😊

  • @TrialImageInc

    @TrialImageInc

    2 жыл бұрын

    Glad it helped Ariel - you can access my entire library of medical videos at trialimage.com

  • @nomercyolan
    @nomercyolan9 жыл бұрын

    Thank you very much , very good video.

  • @TrialImageInc

    @TrialImageInc

    9 жыл бұрын

    Thank you petros

  • @abcardico1654
    @abcardico16549 жыл бұрын

    Great VDO,THANK YOU

  • @TrialImageInc

    @TrialImageInc

    9 жыл бұрын

    Thanks Abcar

  • @rehamhisham8365
    @rehamhisham83653 жыл бұрын

    thank you so much

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    You're welcome Reham! You can access my entire library of medical videos at hppts://trialimage.com

  • @vmz5811
    @vmz58116 жыл бұрын

    veryyy brilliantly explained...want to see more videos of human anatomy like this

  • @TrialImageInc

    @TrialImageInc

    6 жыл бұрын

    Thanks Anugya. You can access my entire video library at www.CalShipleyMD.com

  • @jessicaursua8092
    @jessicaursua80927 жыл бұрын

    Perfect!!

  • @TrialImageInc

    @TrialImageInc

    7 жыл бұрын

    +Jessica Ursua - thanks Jessica! You can see much more at CalShipleyMD.com

  • @zeeshankhan9307
    @zeeshankhan93074 жыл бұрын

    Thank you sir May you live long

  • @TrialImageInc

    @TrialImageInc

    4 жыл бұрын

    Thank you Zeeshan - trialimage.com

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    My pleasure zeeshan! You can access my entire medical video library at trialimage.com

  • @keerthireddy01
    @keerthireddy015 жыл бұрын

    Thanks a ton

  • @TrialImageInc

    @TrialImageInc

    4 жыл бұрын

    Thanks Keerthi www.calshipleymd.com

  • @aishahnoor6742
    @aishahnoor67428 жыл бұрын

    Great! Thanks!

  • @TrialImageInc

    @TrialImageInc

    8 жыл бұрын

    +Aishah Noor thanks! www.CalShipleyMD.com

  • @theGOAT-ml4lw
    @theGOAT-ml4lw6 жыл бұрын

    wow that was so easy to understand

  • @TrialImageInc

    @TrialImageInc

    6 жыл бұрын

    +the GOAT - thanks! Www.CalShipleyMD.com

  • @dr.anushagudimetla1003
    @dr.anushagudimetla10035 жыл бұрын

    Awesome video

  • @TrialImageInc

    @TrialImageInc

    5 жыл бұрын

    Thank you Anusha! Access my entire library www.CalShipleyMD.com

  • @roiebuxbaum1820
    @roiebuxbaum18206 жыл бұрын

    bravo!

  • @TrialImageInc

    @TrialImageInc

    6 жыл бұрын

    +Roie Buxbaum - thanks Roxie! Https://www.CalShipleyMD.com

  • @TroyOi
    @TroyOi7 жыл бұрын

    Very helpful, Dr. Shipley. I've been watching a video lecture series on anatomy by Dr. Anthony Goodman. In his lecture on the CNS, he indicates that CSF is produced by the arachnoid villi and secreted into the sinuses of the brain (as opposed to coming by way of the choroid plexus' villi into the cerebral ventricles, as this video asserts). Dr. Goodman's lecture series is 14 years old. Is his understanding outdated? Also, what is the distinction between a brain ventricle and a brain sinus? Thanks!

  • @TrialImageInc

    @TrialImageInc

    7 жыл бұрын

    Hello David - CSF is produced by the choroid plexuses, and absorbed (not produced) by the arachnoid villi, which facilitate transport into the venous sinuses, which are large channels of venous blood located around the perimeter of the brain, in essence, the sinuses act as large veins, collecting both CSF and venous blood to return it to the heart . (The sinuses are the large areas of blue you'll see in the CSF video.) The ventricles are a series of connected chambers deep within the brain (see the video) which are the sites of CSF production (via chorioid plexuses), and also participate in the flow of CSF. These concepts were taught the same way when I attended medical school some 40 years ago. Hope this helps... Cjs

  • @siwenstokes5930
    @siwenstokes59307 жыл бұрын

    thank you!

  • @TrialImageInc

    @TrialImageInc

    7 жыл бұрын

    +Siwen Seo - you're welcome! Http://www.calshipleymd.com

  • @claudiobiddau5516
    @claudiobiddau55167 жыл бұрын

    helped people number +1

  • @ghazalaarshad3147
    @ghazalaarshad31475 жыл бұрын

    thank you so much it is very helpful

  • @TrialImageInc

    @TrialImageInc

    5 жыл бұрын

    Glad it helped ghazala! Access my entire library at www.CalShipleyMD.com

  • @monish4501
    @monish45015 жыл бұрын

    Sir you are really great.

  • @TrialImageInc

    @TrialImageInc

    5 жыл бұрын

    Thanks Monish! www.CalShipleyMD.com

  • @zaib1081
    @zaib10813 жыл бұрын

    Really useful ❤

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Thank you Zaib! You can access my entire medical video library at trialimage.com

  • @muhammadyaseenmahtaab7820
    @muhammadyaseenmahtaab78205 жыл бұрын

    Thank you Sir... Excellent....

  • @TrialImageInc

    @TrialImageInc

    4 жыл бұрын

    My pleasure Muhammad www.calshipleymd.com

  • @sonikarai8755
    @sonikarai87555 жыл бұрын

    Great video

  • @TrialImageInc

    @TrialImageInc

    5 жыл бұрын

    Thank you Sonika! You can access my entire medical video library at www.CalShipleyMD.com

  • @user-nw7oe7dd6t
    @user-nw7oe7dd6t3 жыл бұрын

    🤩 perfect

  • @TrialImageInc

    @TrialImageInc

    2 жыл бұрын

    Thank you! You can access my entire library of medical videos at TrialImage.com

  • @aazoa43
    @aazoa435 жыл бұрын

    This is useful thanks 👍🏻

  • @TrialImageInc

    @TrialImageInc

    4 жыл бұрын

    Thanks aazoa www.calshipleymd.com

  • @mountainmolerat
    @mountainmolerat Жыл бұрын

    This was terrific. Question if you still happen to see comment: When the csf goes down the spine, does it return to the brain in a circular fashion of sorts, or does it return to the blood stream like it does in the brain? Thanks much.

  • @TrialImageInc

    @TrialImageInc

    Жыл бұрын

    Hi Carol - Even after more than a century of scientific study, the precise manner production, circulation and absorption of CSF is still debated amongst top researchers in the field. To your question, one thing that is currently agreed on is that CSF is a one way flow (unlike blood, which of course leaves and then returns to the heart), and Imis absorbed back into the bloodstream at various points including the arachnoid granulations , and possibly through the lymph system in the neck, as well as other mechanisms as yet unconfirmed. Because of the one way flow, the body must precisely balance both production and absorption in order to maintain CSF pressure within physiological levels. If you're interested in delving into the topic in more detail, here's a link to a fairly recent scientific article on the state of the art thinking regarding CSF. www.ncbi.nlm.nih.gov/pmc/articles/PMC6057699/#:~:text=The%20CSF%20from%20the%20subarachnoid,through%20a%20pressure%2Ddependent%20gradient.

  • @sunglassesnadvil
    @sunglassesnadvil8 жыл бұрын

    great video

  • @TrialImageInc

    @TrialImageInc

    8 жыл бұрын

    Thanks Matthew www.calshipleymd.com

  • @skarpengland
    @skarpengland7 жыл бұрын

    I have a question, i hope you are still answering questions :) Seeing how the Pia mater is the innermost layer connective tissue, going from Periosteum - dura mater, arachnoid, and pia mater covering the brain. Is it continous from say, the parietal lobe, and to the ventricles of the brain? Or are we talking about pia mater covering the external surface of brain, and another tissue called pia mater covering the ventricles of the brain? I am a bit confused about this.

  • @chrismexican21

    @chrismexican21

    7 жыл бұрын

    i am no doctor, however, my understanding is the pia matter acts as a membranous covering that encases both the brain and spinal cord's exterior. I don't believe it penetrates the cerebral cortex, nor do i believe that pia matter covers the brain ventricles. Ventricles are hollow spaces left over from embryonic brain (neural tube) development, which form a network and contain specialized capillaries which filter blood plasma, thus creating csf.

  • @hjm4733
    @hjm47332 жыл бұрын

    I'm wondering how monocytes pass the BBB even though there's tight junctions between the endothelial cells.

  • @TrialImageInc

    @TrialImageInc

    2 жыл бұрын

    Hi HJM - the cell junctions are tight but not impermeable, allowing for the passage of specific ions and cells…

  • @manihaven6239
    @manihaven6239 Жыл бұрын

    i understand well., and now i teach other medical student

  • @dannichols6261
    @dannichols62614 жыл бұрын

    Your animation of the circulation of the CSF is *very* helpful! Thank you for producing it! However I think the downward movement of the CSF in the spinal cord happens in the *central canal* of the spinal cord, not in the arachnoid membrane around it as you showed. I think there's a hole in the bottom of the central canal which allows the CSF to enter the arachnoid & then travel back up through it like you did show (I'm guessing by the beating of cilia 'pumping' it upward?).

  • @dannichols6261

    @dannichols6261

    4 жыл бұрын

    Although maybe I'm confused & wrong, maybe CSF circulates like you say, as I find some things online which suggest that the central canal often occludes as we age, so maybe CSF doesn't circulate *down* it after all, still not yet sure.

  • @TrialImageInc

    @TrialImageInc

    4 жыл бұрын

    Hi Dan - excellent question! the precise sites of production and circulation of the CSF are (like many aspects of human anatomy and physiology) still debated by experts in the field and not completely understood. However, there are a few general statements regarding CSF circulation that I think most current researchers would agree on 1) CSF flows from the ventricular system of the brain into the subarachnoid space which surrounds both brain and spinal cord 2) the majority of CSF (75-90%) returns to the venous system via arachnoid villae (AV) which may be found in both the brain and spinal cord) 3) the remainder is absorbed directly into the lymphatic system, which interfaces with the subarachnoid space around cranial nerves (especially the olfactory nerve) and spinal nerve roots in the spinal cord. Regarding the central canal of the spinal cord, some research has found a small quantity of CSF movement from the subarachnoid space into the central canal, and vice versa, but this does not appear to represent a significant part of CSF circulation, which explains why closure of the central canal does not appear to have an impact on CSF dynamics. This is really a fascinating subject, and there is a great more detail one can get into. Of particular interest to me is research regarding WHY CSF (under normal circumstances) flows from the subarachnoid space across the AV into the venous system. For many years, this was thought to be due to an osmotic gradient (venous blood having a higher osmolality than CSF), but current thinking is that this is more likely due to a hydrostatic pressure gradient. If you’re interested in getting into the topic of CSF circulation in greater detail, here is an excellent review article from 2010 that delves into the history of research findings and conclusions on the subject fluidsbarrierscns.biomedcentral.com/articles/10.1186/1743-8454-7-9 You can access my entire library of medical videos at: www.CalShipleyMD.com

  • @dannichols6261

    @dannichols6261

    4 жыл бұрын

    @@TrialImageInc Thank you Dr. Shipley, I appreciate your detailed answer to my misunderstanding! I've downloaded Pollay's paper, pretty heavy reading for a geezer with some college but no degree. :) Cursory reading suggests a kind of gating response with the villi to reverse pressure gradient? I do have what I hope is a simpler question: are there ventricle *wall* structures, similar to the composite walls of arteries, supporting the ependymal cells which line them? Or do the ependymal cells simply adhere to the adjacent nuclei etc structures & that's it? And perhaps more difficult, if there is Pia *inside* choroid plexus, as reading & pictures suggest, where does it *come* from! I've guessed that it adheres to & follows arteries in as arteries enter the brain through the pia of the meninges, but I've seen both yes&no about that. Thanks again for your answer and the article reference.

  • @ananyamaheshwari6037
    @ananyamaheshwari60375 жыл бұрын

    Thank you! :))

  • @TrialImageInc

    @TrialImageInc

    5 жыл бұрын

    My pleasure Ananya. You can access my entire medical video library at www.CalShipleyMD.com

  • @izzahfarhana7434
    @izzahfarhana74343 жыл бұрын

    Thank you this was very clear

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Thank you Izzah - you can access my entire library of medical videos at trialimage.com

  • @izzahfarhana7434

    @izzahfarhana7434

    3 жыл бұрын

    @@TrialImageInc that's really great thank you. As a 2nd year medical student your videos are super helpful

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    where are you studying Izzah?

  • @izzahfarhana7434

    @izzahfarhana7434

    3 жыл бұрын

    @@TrialImageInc Im studying in Malaysia, Dr :)

  • @stelamajetic5365
    @stelamajetic53656 жыл бұрын

    great, thanks :)

  • @TrialImageInc

    @TrialImageInc

    6 жыл бұрын

    You are welcome Stela - You can access my entire video library at www.CalShipleyMD.com

  • @fiammettagrieco8010
    @fiammettagrieco80104 жыл бұрын

    Hello! Sorry for bothering, I am doing some researches for my engineering thesis about brain-on-chip; firstly this is definitely the best video I've seen so far! thank you so much, everything is so much clearer. I was wondering whether all the contents of this video are still valid even after the discoveries about glymphatic system. Moreover, I was asking to myself if you could suggest me some reliable sources about parameters of the fluids in brain... such as perfusion flow rate, shear stress, clearance, permeability... and this kind of numerical parameters. Thank you so much, I hope you will answer!

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Sorry for the delayed response Fiammetta. If you are referring to the abosorption of CSF, most researchers still believe that the majority of absorption takes place into the Sagittal venous Sinus via the arachnoid granulations. However, there certainly does appear to be some absorption into the lymphatics, especially around the cranial and spinal nerves. Here are some articles that might help: www.ncbi.nlm.nih.gov/pmc/articles/PMC2842089/#:~:text=Systolic%20arterial%20expansion%20causes%20a,space%20and%20the%20spinal%20canal. www.ncbi.nlm.nih.gov/pmc/articles/PMC6057699/ www.ncbi.nlm.nih.gov/pmc/articles/PMC3042981/ Also, regarding the effects of shear stress, here is an article and an animation I prepared regarding diffuse axonal injury due to shear stress: trialimage.com/home-page/stock-medical-animation/neurology-animation-library/diffuse-axonal-injury-video/ trialimage.com/home-page/articles/diffuse-axonal-injury-review/

  • @louisecarbonneau6868
    @louisecarbonneau68686 жыл бұрын

    Hello, could you please tell me what would be the cause and effect of scar tissue located in the L5-S1 lumbar? Once arachnoiditis is set in, the scar tissue starts expanding and impending the natural flow of CSF, thus obstructing the rich proteinated CSF to bath other nerves . Can you comment on this please? Is my deduction correct?

  • @TrialImageInc

    @TrialImageInc

    6 жыл бұрын

    +Louise Carbonneau - hello Louise. While I’m not aware of anything in the medical literature that pinpoints interruption of CSF flow to the spinal nerve roots as a cause of the pain and other nerve based symptoms in Arachnoiditis, it could be a factor. What is more certain is that the scar tissue and associated inflammation which forms around the nerve roots can cause severe pain, numbness and altered sensation in the areas of the body supplied by the nerve roots, as well as localized pain in the spine. I hope this helps...

  • @mahroof_8
    @mahroof_85 жыл бұрын

    One of the textbooks ( Sembulingam Physiology) says that the csf is formed by secretion and active transport mechanism and not by ultrafiltration or dialysis... please clarify

  • @TrialImageInc

    @TrialImageInc

    5 жыл бұрын

    Hello Mohamed - excellent question! Despite much research in the past few decades, the precise mechanism of CSF production has not been proven, and there are many competing theories. Most researchers believe that ultrafiltration and active transport may both play a role. My video portrays one popular current theory. Active transport of ions across the cuboidal epithelium occurs as a result of polarizing charges on the epithelium. Once ions have been transported from the capillaries, across the epithelium, and into the brain ventricle, an osmotic gradient is produced, which draws water from the bloodstream into the ventricles as an ultrafiltrate. I hope this helps... www.CalShipleyMD.com

  • @hasna780
    @hasna7809 жыл бұрын

    Thanx a lot ..

  • @TrialImageInc

    @TrialImageInc

    9 жыл бұрын

    My pleasure Doc - :www.CalShipleyMD.com

  • @SachinSachin-jx8tr
    @SachinSachin-jx8tr2 жыл бұрын

    Thank sir

  • @mansdoctooor
    @mansdoctooor6 жыл бұрын

    Thanks

  • @TrialImageInc

    @TrialImageInc

    6 жыл бұрын

    You are very welcome - access my entire medical video library www.calshipleymd.com

  • @simranjaiswal5402
    @simranjaiswal54026 жыл бұрын

    illustration was too good keep it up

  • @TrialImageInc

    @TrialImageInc

    6 жыл бұрын

    +Simran Jaiswal - thanks Simran - you can access my entire video library at www.CalShipleyMD.com

  • @dastanroy3784
    @dastanroy37847 жыл бұрын

    sir you didnt show where the csf merge in blood..

  • @TrialImageInc

    @TrialImageInc

    7 жыл бұрын

    +Dastan Roy - actually it does. At 4:12 you'll see the CSF moving from the arachnoid granulations into the bloodstream (venous blood)

  • @Muuip
    @Muuip3 жыл бұрын

    Question: Ependymal motile cilia make the spinal fluid flow?

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Great question Muuip! Like production of the CSF, there is controversy regarding just exactly what forces propel it throughout the brain and spinal cord. The ependymal cilia certainly seem to play at least a partial role in moving csf through the ventricles, but most authors seem to agree that some combination of pulsatile forces generated by the systolic expansion of arteries in the central nervous system, and respiration, are involved, but again, exactly how this works is as yet unknown. Here are a couple of links to some interesting scientific articles that touch on this question www.ncbi.nlm.nih.gov/pmc/articles/PMC2842089/#:~:text=Systolic%20arterial%20expansion%20causes%20a,space%20and%20the%20spinal%20canal. www.ncbi.nlm.nih.gov/pmc/articles/PMC6057699/ BTW, you can access my entire medical video library at: trialimage.com

  • @Muuip

    @Muuip

    3 жыл бұрын

    @@TrialImageInc Thank you for the quick informations, very useful for my research on epilepsy. I decided to search for a cure since I have it. Based on this video, your video library deserve everyone's support and attention. Thank you for your great work!

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Thanks Muuip. Good luck with the cure!

  • @theunpredictable1354
    @theunpredictable13542 жыл бұрын

    Wow sir tnx

  • @ahmadtanveer1637
    @ahmadtanveer16376 жыл бұрын

    Hii sir I am suffering with numbness in my head left arm and leg and so much pressure on my eyes and between nose and eyes bone lower back pain , I was in a hospital the took spinal liquid and it was normal doctor sent me to sycolojist,but I don’t have any problem like depressions , can you help me or guide me sir????

  • @TraceLight

    @TraceLight

    5 жыл бұрын

    Ahmad Tanveer you need to see an M.D. in person for that.

  • @kumarnarendra401
    @kumarnarendra4013 жыл бұрын

    Sir please say it is for which class,standard high school or above

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Hi Kumar - high school and above. You can access my entire library of medical videos at trialimage.com

  • @c73media7
    @c73media74 жыл бұрын

    Hi doctor, my uncle met with accident and his head bone near by ear was broken. After 1 week treatment light red with some liquid is came out through ear. So we asked our doctor he said the inside brain liquid is came due to bone broken. It will cured after 10 days slowly by taking regular tablets and injections. But we are very worried and scared. Plz tell me is it really a problem and is that liquid was regenerative. Please please i am looking for your replay.

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Sorry for the delayed response c73. How is your uncle doing?

  • @geoffreyarthur3333
    @geoffreyarthur33332 жыл бұрын

    Wowza

  • @Michael.net-ph9nd
    @Michael.net-ph9nd3 жыл бұрын

    Tnx sir

  • @SunnyII3ridges
    @SunnyII3ridges6 жыл бұрын

    I'm here because of AOT... Enough said. Great Video

  • @TrialImageInc

    @TrialImageInc

    6 жыл бұрын

    Thank you Sunny! Https://www.CalShipleymd.com

  • @Ashish-zx4uc
    @Ashish-zx4uc8 жыл бұрын

    Thanks! sir make more video and help our like student

  • @TrialImageInc

    @TrialImageInc

    8 жыл бұрын

    +ashish yadav - thank you Ashish. Access my entire library here: www.CalShipleyMD.com

  • @Jkstolz
    @Jkstolz5 жыл бұрын

    Wow.

  • @TrialImageInc

    @TrialImageInc

    5 жыл бұрын

    Thank you Arizona!

  • @shamakuma1967
    @shamakuma19676 жыл бұрын

    Ultracentrifugate of plasma is csf

  • @manasdas8793

    @manasdas8793

    6 жыл бұрын

    Ramesh Kumaran not exactly

  • @gurmeetkalra
    @gurmeetkalra3 жыл бұрын

    ❤️👍

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Thank you Gurmeet! You can access my entire library of medical videos at trialimage.com

  • @derarty4290
    @derarty42903 жыл бұрын

    This should be thought in schools... early

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Thank you DerArty! You can access my entire library of medical videos at trialimage.com

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Thanks DerArty. You can access my entire library of medical videos at trialimage.com

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    Thanks DerArty. You can access my entire library of medical videos at trialimage.com

  • @raginald7mars408
    @raginald7mars4085 жыл бұрын

    I promote Brain Health Awareness. We need much more of those tools for daiyl awreness - waht NOT to do, to mess uany further. brain health is the most important factor in our life. No Brainers do not care...

  • @ZAHIRABENCHOHRA
    @ZAHIRABENCHOHRA Жыл бұрын

    سبحانك ربي ماخلقت هذا باطلا فقنا عذاب النار

  • @MrJamesdryable
    @MrJamesdryable3 жыл бұрын

    God damn, I thought it was Sam Harris for a second.

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    😄 you can access my entire medical video library at trialimage.com

  • @LexusFox
    @LexusFox7 жыл бұрын

    Is this what causes that massage sensation when I wake up? I literally don't want to wake up, because it feels like some magical fingers are beautifully massaging my brain.

  • @TrialImageInc

    @TrialImageInc

    7 жыл бұрын

    +Lexus Fox - hi Lexus - I'm not familiar with the sensation you are describing, but if it feels good... www.calshipleymd.com

  • @drrajendrasheregarrajendra3463
    @drrajendrasheregarrajendra34635 жыл бұрын

    True significance of cerebrospinal fluid encapsulating neuron current earthing details of Csf current neutralise open Google Doc Rajendra sheregar And see images videos litreture medical science institution

  • @kalashnikov5038
    @kalashnikov50387 жыл бұрын

    Who else came here because of Attack On Titan?

  • @femalooyt

    @femalooyt

    9 ай бұрын

    What does this have to do with AOT?

  • @femalooyt

    @femalooyt

    9 ай бұрын

    I am 6 years late and I still haven’t watched the anime yet 😬

  • @kalashnikov5038

    @kalashnikov5038

    9 ай бұрын

    @@femalooyt damn its been 6 years since i posted this comment lol, the fluid is how titan powers are transmitted (i think) its been a year since the last part i'm choppy w the lore lmao

  • @leshollenbeck9096
    @leshollenbeck90963 жыл бұрын

    Thank you

  • @TrialImageInc

    @TrialImageInc

    3 жыл бұрын

    My pleasure Les. You can access my entire library of medical videos at trialimage.com

  • @rahul-db6fs
    @rahul-db6fs6 жыл бұрын

    Thank you

  • @TrialImageInc

    @TrialImageInc

    6 жыл бұрын

    You are very welcome Sakshyam!

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