The FIRST person who's mentioned psychological issues with caloric restrictions. Finally!!!! Eating disorders and disordered eating is very prevalent, and no one acknowledges it. Thank you!!!

Great topic and great conversation.

I remember reading an article in Prevention magazine more than 30 years ago about this very topic 🙏

If restricting caloric intake by 20% (that is, 20% lower than ad libitum), this will be a caloric deficit until the body weight is reduced to a stable maintenance stage. Then it is caloric maintenance, at a stable, lower body weight. The reason the weight loss stops, is that the basal metabolic rate (BMR) has lowered. The metabolism has slowed, and this slowdown of the metabolic rate is the mechanism by which lifespan is extended. Correct me if any part of this is inaccurate.

guy is sharp

Each species has a maximum lifespan. When you talk about a 10% or 20% lifespan extension, why don't you compare things to the known maximum lifespan of the species instead of the control group? You say that caloric restriction doesn't work in some strains, you need to tell us the maximum lifespan of that strain and how it compares to the maximum lifespan of the species. Otherwise you're not really telling us anything useful.

The wish you would have asked if he would do fasting if he were young again and his opinion on training while fasting.

So the guy says "lose as little muscle as you can" and "calorie restrict". In general if you calorie restrict over long periods you are going to lose muscle after burning away excess fat. The body is not going to reduce the size of you organs if you calorie restrict. Muscles costs a lot of energy to maintain while fat depots, I guess, do not. Calorie restricting over extended time periods seems seems almost synonomous with carrying around as little muscle tissue as possible. You should have followed up on that.

Low quality, waste of time