Bicarbonate and Ketones with Dr. Chiel Poffe - Science of Getting Faster Podcast Episode 3

Спорт

Exogenous ketones are lauded by many for their endurance performance-enhancing properties, but their impact on blood acidity is detrimental to performance and can even counteract their otherwise positive effects. Dr. Chiel Poffé and his partners conducted a study to learn if bicarbonate unlocks the ergogenic action of ketone monoester intake in endurance exercise, and what they learned was surprising. Tune into this episode to learn the science behind ketones and bicarbonate, and how to introduce them into your training regimen to get faster.
Link to Dr. Poffé's study: www.researchgate.net/publicat...
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TOPICS COVERED IN THIS EPISODE:
00:00 Intro
01:17 Podcast Begins
01:58 - Dr. Poffe’s background and the story of his research on Ketones
02:52 - His research with Dr. Peter Hespel of Deceuninck Quick Step
03:11 - What are ketones and ketone esters?
04:44 - Why would someone want ketones in their blood while exercising?
05:43 - The difference between ketone salts and ketone esters
06:52 - Dr. Poffe’s study and why he decided to combine ketone and bicarbonate
08:55 - Performance of Ketone vs. placebo in the studies
09:55 - What does he think happened in the first study?
10:38 - The new study: introducing bicarbonate and what the purpose is.
11:12 - Why Chad finds the study methodology to be valuable
11:36 - Why his research always seeks to mimic real-world conditions
12:32 - What is Bicarbonate?
13:17 - Buffering systems in skeletal muscle
13:56 - How do you get/ ingest bicarbonate?
14:39 - The study method: How big was it?
15:27 - The study methodology and controls
17:24 - Nate summarizes the study’s efforts, cost of dosage, and amount of dose
19:29 - Timeframe of the test: dinner, morning, and timing of exercise
19:53 - Why was it important to control the amount of carbs ingested?
21:32- What was the dinner given to the subjects?
22:15 - What were the study’s results?
23:19 - Conclusions about how this might apply to a race (and timing limitations)
24:52 - Avoiding gastrointestinal issues with sodium bicarbonate
25:56 - Perception of hunger and appetite in the study groups
28:07 - Asking the subjects to identify what they’d taken (placebo vs. esters, etc)
29:11 - The purpose of blinding power and HR data
30:35 - What the study does and doesn’t suggest about ingesting ketones
31:36 - Blood ketone levels and perception of fatigue
32:04 - Should you always supplement ketones with bicarbonate?
33:11 - Outro
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Пікірлер: 17

  • @stevencarr66
    @stevencarr663 жыл бұрын

    I enjoyed the podcast. Would enjoy seeing more research on the application with shorter races such as XC and CX, as the research was applicable to much longer duration road race simulations. Thanks.

  • @TrainerRoad

    @TrainerRoad

    3 жыл бұрын

    For sure! We need to first find the research that applies to it and then speak to the researchers! If you come across any articles that would be a good fit, feel free to pass them along at trainerroad.com/podcast.

  • @luisferdin8817
    @luisferdin88173 жыл бұрын

    My Cardiovascular, Speed and Endurance has improved dramatically as weeks pass by getting deeper in ketosis by having a ketone body. I accomplished my first 100k Ultra Marathon in ketosis.

  • @donwinston

    @donwinston

    3 жыл бұрын

    You're just getting fitter. Has nothing to do with being in "ketosis". How are the hills? (Oh, you're a runner)

  • @luisferdin8817

    @luisferdin8817

    3 жыл бұрын

    @@donwinston I've trained for years. Hills are just fine. Raced Vermont last year in Ketosis and felt great. When I get off Ketosis from time to time I do get sluggish in my running.

  • @luisferdin8817

    @luisferdin8817

    3 жыл бұрын

    @@donwinston I've done the diet on and off for about two years now and I do perform better in Ketosis.

  • @luisferdin8817

    @luisferdin8817

    3 жыл бұрын

    @@donwinston bro not only a runner lol. Check out my Facebook or Instagram. I can move weight you'll be impressed!

  • @luisferdin8817
    @luisferdin88173 жыл бұрын

    You don't get hungry because your Pancreas is at a resting state. Since your Pancreas is not releasing Insulin to control sugars, glucose etc... That's why you start to not get hungry. Ketones deplete as you go. You need to keep fueling with fats as you go on your event to keep ketone production to keep energy levels high!

  • @kirkprl
    @kirkprl3 жыл бұрын

    It would be interesting to see if starting a race fasted would have similar affects because you'd be using indigenous ketone. For general health, most mornings a have a drink with several spices/herbs, ACV and baking soda. Then for about the first 30-60 minutes of exercise fasted. I wonder what affects that has on glycogen sparing, blood ph and performance.

  • @UbzUnclemax

    @UbzUnclemax

    3 жыл бұрын

    Till the time one starts producing sufficient endogenous ketone bodies (+0,5mmol/l?), after longer than an overnight fast (+12h?), one will have lost too much muscle glycogen in the process as well. Thus, simply: no, it'd be a waste of time and money to experiment with high intensity exercise and fasting together, they just do not mix!

  • @kirkprl

    @kirkprl

    3 жыл бұрын

    @@UbzUnclemax Do you have references to back up those statement? I don't have any actual data to back up my thoughts, thats why i think the study would be interesting. I eat a mostly "paleo'ish" diet, low carb by TR standards, but I do eat rice and sweet potatoes. On the bike I use maple syrup and honey, mostly. I doubt your statement because I don't think sleep depletes muscle glycogen. By no means am I saying your wrong, I just want to be educated. I follow an 80/20 program from Matt Fitzgerald, every day isn't "high intensity" and The Maffetone Method seems to work for a lot of people.

  • @Formula369
    @Formula3693 жыл бұрын

    So ketones spare muscle glycogen during long east bouts of exercise so you have more muscle glycogen left for the higher intensity finish...? Wouldn’t consuming enough carbohydrates during that period do the same thing? Then you could probably take in less bicarb because the ketones aren’t lowering the blood Ph. Definitely more work to be done.

  • @chrisb4491

    @chrisb4491

    3 жыл бұрын

    I thought they said at the beginning that they maintained the same glucose intake as previously because they wanted to compare to their typical racing circumstances. They also pre-loaded with high carb meals as they typically would. So, they would have been consuming carbs along with the ketones/bicarb. I may have misunderstood something though.

  • @patrikragnmark5307
    @patrikragnmark5307 Жыл бұрын

    Why did you put the doctor ia a Echo Chamber 😮🥴

  • @donwinston
    @donwinston3 жыл бұрын

    Ketones are just another energy source. Why would they be "better" than maltodextrin? Don't ketones require more oxygen or is more oxygen needed to create ketones from your fat and exogenous ketones don't have that problem? (Later on after typing this they were saying high intensity is a problem so I guess more oxygen is required for exogenous ketones) Glucose in your blood will spare muscle glycogen also.

  • @TrainerRoad

    @TrainerRoad

    3 жыл бұрын

    A good follow-up question to send to trainerroad.com/podcast! ;)

  • @katrinagwen
    @katrinagwen3 жыл бұрын

    The science content appears to be good stuff on this new format. However I like the team dynamics with the traditional podcast, it keeps me engaged. The audio of the guest is not good either, so I lost interest after 10 mins.

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