APOPTOSIS PART 1: Definition, Causes & Mechanism/Pathways

A series of video tutorials discussing the topics for undergraduates in Pathology
In this 1st part of Apoptosis tutorial , i have discussed Definition, Causes & Mechanism/Pathways
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• Definition of apoptosis
• Causes /conditions where apoptosis is seen
• Understand the mechanism of apoptosis
• Extrinsic pathway
• Intrinsic pathway
A pathway of cell death
Induced
By a tightly regulated suicide program
Found in 1972 John Kerr, Andrew H. Wyllie & Alastair Currie
Greek - mean "falling off" (like leaves falling from a tree)
Also referred to as programmed cell death
PHYSIOLOGICAL CONDITIONS
Embryogenesis
Involution of hormone dependent tissues
Menstruation, menopause, weaning
Loss of cells in proliferating cell populations
Bone marrow, thymus
Removal of self reactive lymphocytes
Death of inflammatory cells after their functions are over
PATHOLOGICAL CONDITIONS
Injured cells which cant be repaired
• DNA damage
• Misfolded protein accumulation
• Viral infections
• Duct obstructions
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Please watch: "WARBURG EFFECT: Hallmark of CANCER. What, Why & How?"
• NEOPLASIA 6: WARBURG E...
~-~~-~~~-~~-~

Пікірлер: 103

  • @Kyle0714
    @Kyle071410 ай бұрын

    I wish you taught pathology at my school. I had no idea that Caspase was a mashup of 3 different things, crazy!

  • @TheSK1199
    @TheSK11995 жыл бұрын

    Thank you sir. Reading robbins is so easy after watching your video

  • @hritvikjain__3594
    @hritvikjain__35944 жыл бұрын

    I generally don’t comment of the educational videos on YT. But if I’m commenting, the shit is really awesome. I was so scared of Apoptosis, that i even decided to skip it for my exams. But after watching this video, the mechanism of apoptosis is very clear to me now. Thank you sir 🙏🏻.

  • @ilovepathologyVijayPatho

    @ilovepathologyVijayPatho

    4 жыл бұрын

    Hritvik Jain thanks 😊 glad you liked it 😊

  • @92soofiyanoushad8
    @92soofiyanoushad83 жыл бұрын

    Sir, this vedio is really an exam capsule 😍.thank you

  • @selvambigaig6541
    @selvambigaig65412 жыл бұрын

    Awesome. Keep up the great work. A real boon for students.

  • @17anandp86
    @17anandp864 ай бұрын

    Such a wonderful class So easy to grasp the topic after hearing your class sir

  • @sindynurafia4063
    @sindynurafia4063 Жыл бұрын

    im coming from country who dont use english as daily basis, so its difficult for me to listen and understanding something in english . you should turn on the subtitle, it would make me easier to understand. at least i can read it.

  • @criticaltruth5184
    @criticaltruth51847 жыл бұрын

    awesome videos. love the details of the caspaces and the IAP family

  • @doc599
    @doc599 Жыл бұрын

    Ahhh.....such a detailed yet precised explanation

  • @kapilnath4059
    @kapilnath40597 жыл бұрын

    Precise Explanation sir . Thank you very much ..

  • @josetrujillo738
    @josetrujillo73810 ай бұрын

    I enjoy your lectures. I appreciate your very great ability to teach

  • @narendrachaudhary609
    @narendrachaudhary6092 жыл бұрын

    Wow..love it❣️ Such a good explanation in short time

  • @arvaoz6799
    @arvaoz67995 жыл бұрын

    Was very helpful! Thank you so much! :)

  • @rianacaeiro8711
    @rianacaeiro87116 жыл бұрын

    Very well explained, thankyou so much.

  • @pakapapita3104
    @pakapapita31046 жыл бұрын

    Thank you so much sir, I read Robbins only after watching your videos.

  • @Artsylove4

    @Artsylove4

    3 жыл бұрын

    Me too

  • @koolshakthi1985
    @koolshakthi19852 жыл бұрын

    This is excellent. Thank you!

  • @Artsylove4
    @Artsylove43 жыл бұрын

    Thank you so so much sir for this tutorial ..❣️

  • @lpangmeiphom1324
    @lpangmeiphom13243 жыл бұрын

    Cleared my basic concept 🤘tq sir

  • @venkateshwarlugangishetty8853
    @venkateshwarlugangishetty88534 жыл бұрын

    Wowww,simply super 👏👏

  • @abhijityeole8462
    @abhijityeole84625 жыл бұрын

    Awesome. Thank you soo much sir!

  • @DrDmitrii
    @DrDmitrii4 ай бұрын

    Thank you brother!

  • @kidzstories2412
    @kidzstories24122 жыл бұрын

    Thank you sir easiest slide & explanations to follow 🙏🙏🙏

  • @anaskp4667
    @anaskp46672 жыл бұрын

    Love your classes

  • @janakignanan7793
    @janakignanan77933 жыл бұрын

    Thanks a lot :) This helped me alot for my degree :)

  • @ananyagupta9730
    @ananyagupta97306 ай бұрын

    Thank you so much. I have much better understanding

  • @shameenabanu1143
    @shameenabanu11433 жыл бұрын

    Thank u so much sir .....it is so. Much clear explanation ....

  • @piyumidissanayake6244
    @piyumidissanayake62447 жыл бұрын

    great sir,thank you

  • @harshaharidas4786
    @harshaharidas47865 жыл бұрын

    Thankuu very muchh sir Very helpful👍👍

  • @samyu7925
    @samyu79255 ай бұрын

    please make more videos like these sir🙏🙏🙏

  • @anushabachchu1273
    @anushabachchu12732 жыл бұрын

    Simple and super sir!

  • @50divyaramesh77
    @50divyaramesh775 жыл бұрын

    Excellent video which explains each and every point clearly😊please do more videos in all topics as possible.

  • @HassanAli-zq3ml
    @HassanAli-zq3ml7 жыл бұрын

    simple and clear

  • @Baharaakbari
    @Baharaakbari Жыл бұрын

    Amazing thank u so much ☺️

  • @nandinimoorthy3163
    @nandinimoorthy31637 жыл бұрын

    super great job

  • @vaisshnavi1257
    @vaisshnavi1257 Жыл бұрын

    Smooth like butter 🧈🤌🫶💥💕💜💜💜💜💜💜💜💜

  • @ilovepathologyVijayPatho

    @ilovepathologyVijayPatho

    Жыл бұрын

    Thank you 😊

  • @TheSandeepkumar1991
    @TheSandeepkumar19916 жыл бұрын

    Thanks you sir..

  • @tahiransari3917
    @tahiransari39175 жыл бұрын

    Very helpful sir

  • @JoohiMahesh
    @JoohiMahesh2 жыл бұрын

    Thank u sir for this lecture

  • @benazirnowshath9002
    @benazirnowshath90024 жыл бұрын

    Could anyone give explanation more than this for apoptosis?! Really awesome sir🙌

  • @puneetsharma1134
    @puneetsharma11347 жыл бұрын

    thankew sir.

  • @phoolphool396
    @phoolphool3962 жыл бұрын

    Really helpful video

  • @padmamahindravada
    @padmamahindravada4 жыл бұрын

    Excellent video. very clear. Thank you sir

  • @ilovepathologyVijayPatho

    @ilovepathologyVijayPatho

    4 жыл бұрын

    Glad it was helpful!

  • @polokocollen7072
    @polokocollen70726 жыл бұрын

    Thank you.

  • @SMM-qp9ig
    @SMM-qp9ig4 жыл бұрын

    Gorgeous way

  • @user-qk4hn5ce9x
    @user-qk4hn5ce9x Жыл бұрын

    thank U 👍

  • @13.tarunchandwani51
    @13.tarunchandwani514 жыл бұрын

    Thank you sir

  • @shitalsurushe7496
    @shitalsurushe74965 жыл бұрын

    Thank you

  • @abhi-wi2mj
    @abhi-wi2mj4 жыл бұрын

    Explanation was very nice.

  • @ilovepathologyVijayPatho

    @ilovepathologyVijayPatho

    4 жыл бұрын

    Glad you liked it

  • @rutujamohite4890
    @rutujamohite48902 жыл бұрын

    A Great Thank you

  • @21aparnamadhusoodanan94
    @21aparnamadhusoodanan942 жыл бұрын

    Thankyou sir❤️

  • @shahnasshajahan529
    @shahnasshajahan5292 жыл бұрын

    Thank you 💟😊

  • @suman-by7gt
    @suman-by7gt2 жыл бұрын

    thanks so much

  • @shashishah7887
    @shashishah78872 жыл бұрын

    could you please elaborate how the molecules on inner side of cell membrane got to be on the outside?because that's what caused phagocytosis...

  • @sebastianm.6875
    @sebastianm.68756 жыл бұрын

    amazing

  • @fatahabdinur5383
    @fatahabdinur53832 жыл бұрын

    ty bro

  • @Daawonuurka
    @Daawonuurka Жыл бұрын

    Thank you From Somalia 🤒🥲

  • @nagamanigv8225
    @nagamanigv82257 жыл бұрын

    Thank you sir nyc teach

  • @ikramshehzad6936
    @ikramshehzad69363 жыл бұрын

    Thanks 😊 sir which one book you following?? For better understanding of pathology

  • @doc599

    @doc599

    Жыл бұрын

    Robbins pathology

  • @fatahabdinur5383
    @fatahabdinur53832 жыл бұрын

    saved my life

  • @JackT13
    @JackT136 жыл бұрын

    I like the video but I thought apoptosomes were heptamers (7 sub-units)?

  • @sabreenmodak7746
    @sabreenmodak77463 жыл бұрын

    Can i please know the name of the book that you've referred here?

  • @zainabalradi2306
    @zainabalradi23066 жыл бұрын

    you are a god

  • @laurachueire4625
    @laurachueire46253 жыл бұрын

    perfect

  • @user-iw9ps3oj9l
    @user-iw9ps3oj9l6 ай бұрын

    ❤❤❤

  • @sainiksefteri7832
    @sainiksefteri78325 жыл бұрын

    how apoptotic factors are occurred and where? Due to WHAT?

  • @chagalamukamorris4744
    @chagalamukamorris47443 ай бұрын

    Chagalamuka used this ❤

  • @pubsmedworld101
    @pubsmedworld101 Жыл бұрын

    Best teacher for pathology

  • @ilovepathologyVijayPatho

    @ilovepathologyVijayPatho

    Жыл бұрын

    Thank you 😊

  • @rosejasmine4214
    @rosejasmine42146 жыл бұрын

    Very useful👍👍👍 thank you

  • @user-wh1ev7gq6o

    @user-wh1ev7gq6o

    6 жыл бұрын

    H7

  • @hibakaleed387
    @hibakaleed3875 ай бұрын

    Please can I get this file I need to study it ?

  • @ursgp7
    @ursgp72 жыл бұрын

  • @tejasgadekar6153
    @tejasgadekar6153 Жыл бұрын

    👍

  • @Rohit-fy4kl
    @Rohit-fy4kl2 жыл бұрын

    Sir which book you are following

  • @jaydeepchauhan7712
    @jaydeepchauhan77124 жыл бұрын

    sir this is the fantastic explanation, sir...can you please make a telegram channel for multiple choice questions practice,so that we can apply the knowledge of pathology

  • @ilovepathologyVijayPatho

    @ilovepathologyVijayPatho

    4 жыл бұрын

    Thanks so much :-) I think there is already a telegram channel for MCQs practice.. you can join that

  • @jaydeepchauhan7712

    @jaydeepchauhan7712

    4 жыл бұрын

    @@ilovepathologyVijayPatho can you mention the name ....plzz sir

  • @ilovepathologyVijayPatho

    @ilovepathologyVijayPatho

    4 жыл бұрын

    jaydeep chauhan "pathology UG Quiz😊"

  • @saloniparekh8419
    @saloniparekh84196 жыл бұрын

    This is so simple and easy to understand.R u from india?

  • @ilovepathologyVijayPatho

    @ilovepathologyVijayPatho

    6 жыл бұрын

    sanjana parekh thanks 😊 and Yes!

  • @anaskp4667
    @anaskp46672 жыл бұрын

    Could you please share the ppt

  • @anaskp4667
    @anaskp46672 жыл бұрын

    Sir

  • @pavanjadhav5116
    @pavanjadhav51162 жыл бұрын

    Thank you sir....still I hate patho😭

  • @ilovepathologyVijayPatho

    @ilovepathologyVijayPatho

    2 жыл бұрын

    Wish I could make it interesting for you 😊

  • @imanehdjb402
    @imanehdjb4023 жыл бұрын

    S'il vous plaît, quelqu'un me traduit les causes de l'apoptose en français

  • @pheonixheart5534
    @pheonixheart55344 жыл бұрын

    💜💜💜🏌️‍♀️

  • @nativetexan6628
    @nativetexan66283 жыл бұрын

    I'm sure your video is very good, but I couldn't understand the words you were saying. I got a few words but your accent is so heavy that I just couldn't get it. I am so sorry.

  • @ourvinesshahzad3931
    @ourvinesshahzad39315 жыл бұрын

    Thank you sir

  • @abhi-wi2mj
    @abhi-wi2mj4 жыл бұрын

    Thank you.

  • @ilovepathologyVijayPatho

    @ilovepathologyVijayPatho

    4 жыл бұрын

    You're welcome!

  • @rikkigupta9546
    @rikkigupta95464 жыл бұрын

    Thanks alot sir

  • @ilovepathologyVijayPatho

    @ilovepathologyVijayPatho

    4 жыл бұрын

    Most welcome