"What is Apoptosis?" The Apoptotic Pathways and the Caspase Cascade
This 3D medical animation explains the functioning of the extrinsic and intrinsic apoptotic pathways. We start off by taking a look at the important role apoptosis plays in growth and development as well as removing DNA damaged cells. Then we see how activation of the caspase cascade occurs in each external and internal signalling pathway. Lastly we get a glimpse of cancer cells and their ability to block apoptosis.
© Elvire Thouvenot-Nitzan, 2016
www.elvirethouvenot.com
This resource is shared under Attribution-NonCommercial-NoDerivatives Creative Commons license (CC-BY-NC-ND 4.0). You are free to copy and reuse this for non-commercial purposes but we ask that you acknowledge “Elvire Thouvenot-Nitzan, created in collaboration with University of Dundee” when doing so. If you remix or modify this material, you may not distribute the modified material.
Medical Animator
Elvire Thouvenot-Nitzan BSc, MSc
Centre for Anatomy and Human Identification, University of Dundee
Medical Advisor and Pathology Instructor
Richard Oparka MBChB, FRCPath
Department of Histopathology, University of Dundee School of Medicine
MSc Medical Art Advisor
Caroline Erolin BA(Hons), PGCert, MPhil
Centre for Anatomy and Human Identification, University of Dundee
Technical Advisor
Annie Campbell BSc, MSc
Technology & Innovation Learning Team, University of Dundee School of Medicine
Attributions:
This animation features the track “Enrichment” by Podington Bear. The track is licensed under CC BY-NC 3.0 and has been edited to fit the animated short.
freemusicarchive.org/music/Podington_Bear/Backbeat/Enrichment
The animation features sound effects from freesfx.co.uk.
Пікірлер: 399
How about a round of applause for the people made this?
@Lotus-mz5wn
3 жыл бұрын
How about a round of applause for the Who created this creativity?😊
@mangiemuncheez3130
3 жыл бұрын
Oh yes definitely 👏👏👏👏👏👏
@saiyemiftekhar9993
2 жыл бұрын
Definitely. Kudos to people who made this.
@meorhakim7139
2 жыл бұрын
Sir yess sir!!
@mikecullinan2226
2 жыл бұрын
I really liked the Fazballs and Fazbeans
i LOVE that clicking noise when caspases activate one another 1:50
@ramen4695
4 жыл бұрын
SATISFYING
@gabrielahimsa4387
3 жыл бұрын
same im triggered
@umamasiddiqa3205
3 жыл бұрын
Haha same
@arishaquazi964
3 жыл бұрын
😂😂yes
@vivavida6748
2 жыл бұрын
Right with all those sounds I get the whole process. I love this video.
this was oddly very soothing to watch
@Ramora-hu2wb
7 жыл бұрын
George Partington I KNOW omg so relaxing
@Lotus-mz5wn
3 жыл бұрын
Yaaaaah, I am truly influenced by the greatness of the Creator 🙆♀️
You made apoptosis so cute ! The bubbles and the popping sounds Are 💘
@naeemchaudhary4728
3 жыл бұрын
Love U 💞🤩
the best video on apoptosis ever seen
@aminaamii3237
4 жыл бұрын
True
@parkmicrosoft3638
3 жыл бұрын
Are you from china
This is by far one of the best biochemistry videos I've ever seen! :) Literally didn't wanted it to end!
pretty sure this is the cutest, most satisfying and relaxing biochemistry video ive ever seen
Whoever animated this deserves a Nobel Prize and a contract with every school in the world
Yes, round of applause. Excellent animation and animation.
Very easy to remember the difference between intrinsic and extrinsic after seeing this animation, thank you!
This is one the best biology videos I've ever seen. Highly appreciated. Thankyou.
@kaylaknaperek8320
8 ай бұрын
still one of the best biology videos I've ever seen, and graphics have only gotten better since five years ago:')
I really want more of this .... This is evolutionary ✨✨ Respect and love for all who made this ! It's absolutely peaceful and amazing ❤️❤️❤️❤️❤️❤️❤️❤️
ASMR: The educational version
You're gonna love apoptosis after watching this
This turned my frown upside down, thanks! I gleefully bobbed my head up and down as I made notes and consolidated my understanding after stumbling through pages upon pages of module text!
This video is amazing!! Great animations, sound effects, a clear script which is basic enough to follow along, and a great narrator! Well done
I kept smiling while watching this video. It's so well-made! Thanks so much!
@naeemchaudhary4728
3 жыл бұрын
Same here chootye am also like this vodeo
i usually don't like to comment in youtube videos but after watching this i think you deserve a thank you from my heart one of the best videos in medical field that i have ever seen
This has totally chilled me out during extreme exam stress - thank you!
This the best video I’ve ever seen in my entire life! 1 hour lecture about apoptosis and not a single thing in my brain. But this!!!!!
Awesome! We (as in I) need more animated videos like this! This is how I learn the best.
Caspases are so cool
one of the most explicit and simple to understand videos
There is no better way to describe the process! Splendid animation!
Thank you so much for sharing this with us. This video makes it so clear and easy to understand a rather complex concept. Respect to the people who made this!
This is awesome!!!! I, have never seen a more simplified yet conscised explanation of Apoptosis. My standing ovation🙌🙌🙌
This was helpful thank you. Strangely it was really satisfying too! The noises of the cascade and fas ligand binding where particularly satisfying. Great job.
Cant get better than this! The best video on apoptosis I ever came across. Thanks a lot!
This is the best video I have watched an apoptosis so far, I am learning while enjoying the music in the background, this is awesome
The best video for apoptosis! thank you, whoever made this amazing video
This is the best scientific video I have ever seen
This is one of the best videos I've ever seen in my life. Just wow! Thank you all so much for this remarkable creation.
beautifully explained and visually stunning
This is one of the most helpful videos I've seen! The sound effect is oddly satisfying as well ;^)
WE NEED THIS IN OUR LIVES
I have never seen apoptosis made this easy. This is wonderful. Great job!!
Wow that was so down to earth and well illustrated. nice vid!!
The animations are so satisfying to watch, and well explained!
The sound of the activation of caspase cascade is relaxing.
The bestest video for apoptosis biochemical changes
Amazing video! Great visuals!
I love this! Simple and well-explained!
Thank you so much, now I can put it all together in my head, before I was confused by the details. :)
Thanks you!!!! Love that you made this understandable to the general population who lack a scientific background. Excellent video!
I loved the animation - this was so easy to understand!
i can’t describe how great this is
Thank you! For the clear and well presented work 😍
That was magnificant!!!
thanks alot for this spectacular illustrative animation, it was very explanatory
Beautiful sound effects!
One of the best animation video. Thank you!
how beautifully explained by making such meaningful animation. Truly impressed by seeing caspases.
@elvirethouvenot-nitzan1784
7 жыл бұрын
Thank you for your comment! You might also enjoy some of the other University of Dundee biomedical animations available at vimeo.com/dundeetilt.
This is the most adorable explanation of apoptosis.
Thanks a lot for this wonderful video. I have understood the topic in just some minutes even I once did not understand it by reading book ....
Im biology student in university. Tomorrow I have a molecular biology exam. This video is very helpfull for me thank you so much. Good luck.
Simply Amazing Guys,keep up the good work.👍😊
Very good illustration and clear voice. Thank you
I’m so lucky to have this video, many thanks 💕💕💕💕
could not understand a single thing my teacher was talking about thank u sm for this video 🙏🏼🙏🏼
From 2nd yr of my med school untill now in my pg prep days it's always been my 1st choice revise apoptosis.. thanx for making this incredibly concise yet high yielding vdo
i have seen many videos about apoptosis but this one is by far the best one it was very simple and contains at the same time every thing you should know
THIS IS SO GOOD AND SOOTHING TO WATCH
I love the explanations, very smooth
Best video on apoptosis Nicely animated To be precise cutely done
Best video on apoptosis ! Super easy explanation
this is the best explanation I've seen thank you so much
What a fancy explanation! I cannot thank you enough for this great work ❤️
SUPERB . ROUND OF APPLAUSE FOR YOU GUYS.
more of those videos ! awesome animation
Thank you so much!!!!!!! this was so useful and well made
👏👏👏👏 Thank you so much.. I highly appreciate the efforts of makers
Love this visual approach
This is such a helpful video - thank you so much!
back again and still the best on you tube
Awesome video...excellent explanation.. Thank u so much
Wow, really great work.
Woww I thanked for whoever made this !!! It so easy to understand and helps a lot !!!
Very well explained. Thanks a lot
This was really helpful. THANK YOU
Wonderful explanation
nice animation, excellent explanation ! . thanks
Really good animation on apoptosis ever seen in youtube Great man thank u ☺️😊
This is simply phenomenal video content!!! 🙏
This is perfect!!
This is amazing! Thank you for this video.
ha, it makes so much sense now! Thank you! Very helpful.
Great! Great! Great! I watch A LOT of medical and A&P videos. This was not just uniquely beautiful to watch (honestly, probably a first in the thousands of medical videos I've watched), but you also did a wonderful job of isolating key concepts and explaining them clearly. (One thought-- You may want to explain how cancers promote their own survival by blocking apoptosis. I'm not sure everybody would infer that. But that is a very small criticism in light of your accomplishment.). Wonderful job, both educationally and artistically.
Excellent video, this is one of the best video biology i've ever seen, Thanks you👍
Thank you so much! Great job !!! I will recommend it for my students !
Excellent video, thank you!
Stunning!
awesome video very much helpful
Congratulations for the amazing video.
thank you so much for making this it has been immensely helpful
I love this animation and clicking sound
So amazing. Thank you
Such an awesome video.
A great video! Thank you.
Bro this is beautiful!
Awesome explanation