Alkene Epoxidation Reaction and Mechanism Using Peroxy acid or mCPBA

leah4sci.com/alkene-reactions/ Presents: Epoxidation of alkenes - reaction and mechanism for converting an alkene to epoxide.
Need help with orgo? Download my free guide '10 Secrets to Acing Organic Chemistry' HERE: leah4sci.com/orgo-ebook/
This video takes you through the reaction and mechanism for alkene epoxidation. Starting with an understanding of peracids including mCPBA (meta chloroperbezoic acid) followed by a shortcut to quickly identifying products.
And finally a full color explanation of the cyclic 'concerted' mechanism for reacting the peroxy acid with an alkene.
Catch my entire Alkene Reactions video series on my website: leah4sci.com/alkene-reactions/
For more in-depth review including practice problems and explanations, check out my online membership site: studyhall.leah4sci.com/join
For private online tutoring visit my website: leah4sci.com/organic-chemistry...
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Пікірлер: 113

  • @kushamaharshi7401
    @kushamaharshi74018 жыл бұрын

    Your videos are precise yet comprehensive. Well explained and not painstakingly long. It's rare to find these qualities in online chemistry videos. Very well done. :))

  • @Leah4sci

    @Leah4sci

    6 ай бұрын

    Thanks so much for your kind words, happy to help

  • @alohomora394
    @alohomora3949 жыл бұрын

    u ever wonder how ppl found all o f this out????

  • @gartyqam

    @gartyqam

    4 жыл бұрын

    they hav no life

  • @russp1212

    @russp1212

    4 жыл бұрын

    literally all the time, like wtf

  • @JespMusic

    @JespMusic

    3 жыл бұрын

    It's very similar to music theory believe it or not

  • @flow4458

    @flow4458

    3 жыл бұрын

    @@gartyqam Yeah, if all those smart asses had a life, a lot of others with a life would be dead; without this shit no drug and pill would be on this earth...

  • @momsspaghetti8093

    @momsspaghetti8093

    3 жыл бұрын

    @@gartyqam Nah they prolly got a better life than you lil kid

  • @rossclydesimonvil4875
    @rossclydesimonvil48752 жыл бұрын

    you are so simple in your explanations your dumb it down for us that are not so good in O Chem thanks a lot Mrs Leah.

  • @Leah4sci

    @Leah4sci

    2 жыл бұрын

    You're so welcome! It's not dumbing it down, though. It's just finding a way that makes it easier to understand. The subject and the students are still just as smart ;)

  • @patchworkgirl27
    @patchworkgirl275 жыл бұрын

    Leah You are saving my academic life!!!! I wish I could afford ur tutoring sessions!!! Thank you for these videos! from one nerd to another

  • @Leah4sci

    @Leah4sci

    5 жыл бұрын

    You're welcome Nati. Glad the channel helped.

  • @divyanshurawat9083
    @divyanshurawat90837 жыл бұрын

    awesome explanation... learning orgo was never such easier... thanks a lot.. great work😃😃

  • @Leah4sci

    @Leah4sci

    7 жыл бұрын

    Glad it helped!

  • @JespMusic
    @JespMusic3 жыл бұрын

    Thanks for explaining this mechanism. It's fascinating!

  • @Leah4sci

    @Leah4sci

    3 жыл бұрын

    Glad you liked it!

  • @ManojTaneja1958
    @ManojTaneja19589 жыл бұрын

    Maam I am from India. These videos are very useful to me . Thanks to u for uploading these videos.

  • @shahbaazali1195

    @shahbaazali1195

    7 жыл бұрын

    same here, life saver !!

  • @Leah4sci

    @Leah4sci

    5 ай бұрын

    You're so welcome!

  • @teyang.
    @teyang.2 жыл бұрын

    YOU'RE MAGIC ! thank you for your videos queenn

  • @Leah4sci

    @Leah4sci

    2 жыл бұрын

    You're so welcome!

  • @jobsyjose625
    @jobsyjose6257 жыл бұрын

    The way you teach is amazing..

  • @Leah4sci

    @Leah4sci

    7 ай бұрын

    So happy to help!

  • @rasadokht
    @rasadokht3 жыл бұрын

    you totally saved my life.thank you sooo much.

  • @Leah4sci

    @Leah4sci

    3 жыл бұрын

    I'm so glad to help!

  • @shanemichael9011
    @shanemichael90116 жыл бұрын

    Very good video !! Well understood. However, I only wished I saw this video months ago before learning this mechanism by means of a much more difficult way !

  • @Leah4sci

    @Leah4sci

    5 жыл бұрын

    Glad the video helped you understand the topic better! You are very much welcome!

  • @shrimanpatil
    @shrimanpatil4 жыл бұрын

    so wonderfully explained Leah 💖💖💖💖💖💖💖

  • @Leah4sci

    @Leah4sci

    4 жыл бұрын

    Glad you liked it!!

  • @chillydoog
    @chillydoog7 жыл бұрын

    WOW. Ive never thought of using butter as a reagent before. Ill have to try that!

  • @Leah4sci

    @Leah4sci

    7 ай бұрын

    :)

  • @eman4159
    @eman41593 ай бұрын

    thank you so much for this amazing video💕💕 did you explain the topic that follows alkene epoxidation (anti and syn dihydroxylation)?

  • @Leah4sci

    @Leah4sci

    3 ай бұрын

    You can find my entire alkene series here: leah4sci.com/alkene-reactions/

  • @khyzer1114
    @khyzer11147 жыл бұрын

    Thanks! This has been very helpful.

  • @Leah4sci

    @Leah4sci

    6 ай бұрын

    you're very welcome!

  • @sheagallagher95ify
    @sheagallagher95ify9 жыл бұрын

    Thanks Leah Fisch! Now I have a hope in passing my 1st year of Chem BSc! hahaha

  • @Leah4sci

    @Leah4sci

    5 ай бұрын

    You're very welcome!

  • @Shreyaraman2005
    @Shreyaraman200510 ай бұрын

    I have a doubt. Alkenes on oxidation with Baeyer's reagent give us diols as our products. Does this follow the same, or some similar mechanism of alkene epoxidation? This is because in my textbook, alkene epoxidation is omitted and many other reactions are present such as polymerisation, Addition of Sulphuric Acid, Oxidation (as given above) and etc.

  • @Leah4sci

    @Leah4sci

    10 ай бұрын

    I'm sorry, but I don't offer tutoring over social media. For help with questions like this and more, I recommend joining the organic chemistry study hall. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/

  • @BoBo-kg1me
    @BoBo-kg1me4 жыл бұрын

    You saved the day for me # Thank you Leah

  • @Leah4sci

    @Leah4sci

    4 жыл бұрын

    Awesome! You're very welcome!

  • @nipamehta4556
    @nipamehta45566 жыл бұрын

    Excellent explanation

  • @Leah4sci

    @Leah4sci

    6 жыл бұрын

    Glad you enjoyed it!

  • @imnobody7226
    @imnobody72263 жыл бұрын

    Mam can you please upload or tell me if you have uploaded video for diels alder reaction??

  • @Leah4sci

    @Leah4sci

    11 ай бұрын

    I have a short series on the Diels Alder Reaction that you can find at leah4sci.com/diels-alder-reaction-mechanism-organic-chemistry/

  • @ACDBunnie
    @ACDBunnie2 жыл бұрын

    Did you ever make a video on how to open an epoxide? (like what you do in anti-dihydroxylation)

  • @Leah4sci

    @Leah4sci

    2 жыл бұрын

    I have not made a KZread video on epoxide ring-opening reactions, but you can find this and more in my Organic Chemistry Study Hall. I recommend joining to dive deep into this reaction and others. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/

  • @patriciagomani6097
    @patriciagomani6097 Жыл бұрын

    Well summarized

  • @Leah4sci

    @Leah4sci

    Жыл бұрын

    Glad you liked it, thanks for watching!

  • @khizrabatool9989
    @khizrabatool99892 жыл бұрын

    Your vids help a loooot

  • @Leah4sci

    @Leah4sci

    2 жыл бұрын

    Glad to hear that!

  • @anandreddy2992
    @anandreddy29926 жыл бұрын

    Will this apply to sharpless asymmetric epoxidation

  • @Leah4sci

    @Leah4sci

    6 жыл бұрын

    I'm not familiar enough with that reaction to answer your question.

  • @alone.3885
    @alone.38852 ай бұрын

    i want the free book how can i get the book ?

  • @Leah4sci

    @Leah4sci

    2 ай бұрын

    You can sign up here: leah4sci.com/orgosecrets

  • @Patrick-gw1vp
    @Patrick-gw1vp5 жыл бұрын

    Very helpful. Thank you

  • @Leah4sci

    @Leah4sci

    5 жыл бұрын

    You're welcome! Glad to help! :)

  • @svnspell6709
    @svnspell67092 ай бұрын

    This is a dumb question but at 5:18 why would alkene break its pi bond and use its electrons to attack oxygen?

  • @Leah4sci

    @Leah4sci

    2 ай бұрын

    no question is a dumb question, you ask so you can learn. The pi bond is nucleophilic and while it appears happy, it can easily be enticed to break and attack an electrophile. In the case of oxgyen, because the O-O is very weak and unstable, it's very reactive. (the oxidation number of a peroxide is only -1 making it more susceptible to be attacked compared to the happy -2 oxygen)

  • @svnspell6709

    @svnspell6709

    2 ай бұрын

    Thankyou!♡

  • @dr.asmaaibrahim2671
    @dr.asmaaibrahim26713 жыл бұрын

    That is great video ♥️

  • @Leah4sci

    @Leah4sci

    3 жыл бұрын

    Thank you!!

  • @LIZ-vc1pr
    @LIZ-vc1pr3 жыл бұрын

    how would one go from trans alkene to cis epoxide? or cis alkene to trans epoxide?

  • @Leah4sci

    @Leah4sci

    2 жыл бұрын

    flip the alkene first (dihalide -> alkyne -> partial reduction)

  • @sydaanees2710
    @sydaanees27104 жыл бұрын

    Quality teaching mam amazing

  • @Leah4sci

    @Leah4sci

    4 жыл бұрын

    Aww thanks!

  • @myettedupreez6664
    @myettedupreez66644 жыл бұрын

    thank you Leah!

  • @Leah4sci

    @Leah4sci

    4 жыл бұрын

    You're very welcome!

  • @zhalehdorostkar4462
    @zhalehdorostkar44628 жыл бұрын

    you are great thanks

  • @Leah4sci

    @Leah4sci

    5 ай бұрын

    You're very welcome!

  • @piyushmajgawali1611
    @piyushmajgawali16118 жыл бұрын

    are you the person who made Fischer projections??

  • @Leah4sci

    @Leah4sci

    6 ай бұрын

    lol, nope!

  • @debayandas3146
    @debayandas31464 жыл бұрын

    Thank you

  • @Leah4sci

    @Leah4sci

    4 жыл бұрын

    You're welcome!

  • @radhhpatel
    @radhhpatel8 жыл бұрын

    thank you!

  • @Leah4sci

    @Leah4sci

    5 ай бұрын

    You're very welcome!

  • @tishkaras9499
    @tishkaras94997 жыл бұрын

    thanks

  • @Leah4sci

    @Leah4sci

    7 ай бұрын

    You're welcome

  • @littleuwu296
    @littleuwu2964 жыл бұрын

    Thank youu💕💕💕

  • @Leah4sci

    @Leah4sci

    4 жыл бұрын

    You're welcome!

  • @CliffStamp
    @CliffStamp7 жыл бұрын

    Why does this reaction start? Why does the pi bond attack the oxygen with two lone pairs already? What makes that oxygen electrophilic?

  • @minjungkim3144

    @minjungkim3144

    7 жыл бұрын

    it also looks strange to me.

  • @aman-tl9gd

    @aman-tl9gd

    6 жыл бұрын

    unstability of peroxy acid is driving force of mechanism .

  • @itsdwish

    @itsdwish

    6 жыл бұрын

    So I understand that peroxy acid and it's instability is the driving force of the mechanism, but I don't understand (as the original question asks) why her first step is the pi bond attacking an oxygen. Can anyone elaborate?

  • @aaronholder6294

    @aaronholder6294

    6 жыл бұрын

    the oxygen isn't the electrophile, in this case, the oxygen is slightly negative because it draws the electrons from the hydrogen atom closer to itself making it slightly more reactive than the adjacent oxygen which is attached to a carbon (an electron donating group). The pi bond, on the other hand, is electrophilic in this case (since carbon prefers to have all single bonds instead of sharing electrons). as a result, the (electrophilic) pi bond attacks the unstable electron rich to try to saturate itself. when it does this the electrons from the pi-bond between the carbons move to attack the oxygen and as a result, leaves the adjacent carbon electron deficient with a positive charge. The oxygen, still being electron rich then attacks this positive charge and gives up its proton to help stabilize the charge (if it held onto the hydrogen it would have a + formal charge and would still need to get rid of the hydrogen somehow ).

  • @datumclasses6245

    @datumclasses6245

    6 жыл бұрын

    actually this can be understood by HOMO LUMO concept.

  • @rittenbrake1613
    @rittenbrake16136 жыл бұрын

    very good

  • @Leah4sci

    @Leah4sci

    7 ай бұрын

    Thanks

  • @massarsar2726
    @massarsar27263 жыл бұрын

    i can't thank u enough

  • @Leah4sci

    @Leah4sci

    3 жыл бұрын

    You're so welcome!

  • @msfranny16
    @msfranny168 жыл бұрын

    thanksssss!!!!!

  • @Leah4sci

    @Leah4sci

    6 ай бұрын

    You're so welcome!

  • @binod3028
    @binod30283 жыл бұрын

    Anti or syna addition

  • @Leah4sci

    @Leah4sci

    2 жыл бұрын

    Epoxides are very tight rings and cannot exist anti

  • @Anshu534
    @Anshu5343 жыл бұрын

    Wow👌👌👌👍👍

  • @Leah4sci

    @Leah4sci

    3 жыл бұрын

    😊

  • @ayeshanoor859
    @ayeshanoor8597 жыл бұрын

    thnksssss

  • @Leah4sci

    @Leah4sci

    7 жыл бұрын

    welcome

  • @mohaimenhameed698
    @mohaimenhameed6987 жыл бұрын

    thanks a lot .do you have email please

  • @Leah4sci

    @Leah4sci

    7 жыл бұрын

    This is probably too late, but you can contact me here: leah4sci.com/contact/

  • @yasaine7896
    @yasaine78966 жыл бұрын

    goddess!!

  • @Leah4sci

    @Leah4sci

    6 жыл бұрын

    Thanks?

  • @roshanpatel4037
    @roshanpatel40376 жыл бұрын

    will u marry me plz

  • @Leah4sci

    @Leah4sci

    6 жыл бұрын

    Umm...how about we keep our relationship professional?

  • @zahraakareem8199
    @zahraakareem81996 жыл бұрын

    Thank you

  • @Leah4sci

    @Leah4sci

    6 жыл бұрын

    You are very welcome!