Alkene Epoxidation Reaction and Mechanism Using Peroxy acid or mCPBA
leah4sci.com/alkene-reactions/ Presents: Epoxidation of alkenes - reaction and mechanism for converting an alkene to epoxide.
Need help with orgo? Download my free guide '10 Secrets to Acing Organic Chemistry' HERE: leah4sci.com/orgo-ebook/
This video takes you through the reaction and mechanism for alkene epoxidation. Starting with an understanding of peracids including mCPBA (meta chloroperbezoic acid) followed by a shortcut to quickly identifying products.
And finally a full color explanation of the cyclic 'concerted' mechanism for reacting the peroxy acid with an alkene.
Catch my entire Alkene Reactions video series on my website: leah4sci.com/alkene-reactions/
For more in-depth review including practice problems and explanations, check out my online membership site: studyhall.leah4sci.com/join
For private online tutoring visit my website: leah4sci.com/organic-chemistry...
Finally, for questions and comments, find me on social media here:
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Пікірлер: 113
Your videos are precise yet comprehensive. Well explained and not painstakingly long. It's rare to find these qualities in online chemistry videos. Very well done. :))
@Leah4sci
6 ай бұрын
Thanks so much for your kind words, happy to help
u ever wonder how ppl found all o f this out????
@gartyqam
4 жыл бұрын
they hav no life
@russp1212
4 жыл бұрын
literally all the time, like wtf
@JespMusic
3 жыл бұрын
It's very similar to music theory believe it or not
@flow4458
3 жыл бұрын
@@gartyqam Yeah, if all those smart asses had a life, a lot of others with a life would be dead; without this shit no drug and pill would be on this earth...
@momsspaghetti8093
3 жыл бұрын
@@gartyqam Nah they prolly got a better life than you lil kid
you are so simple in your explanations your dumb it down for us that are not so good in O Chem thanks a lot Mrs Leah.
@Leah4sci
2 жыл бұрын
You're so welcome! It's not dumbing it down, though. It's just finding a way that makes it easier to understand. The subject and the students are still just as smart ;)
Leah You are saving my academic life!!!! I wish I could afford ur tutoring sessions!!! Thank you for these videos! from one nerd to another
@Leah4sci
5 жыл бұрын
You're welcome Nati. Glad the channel helped.
awesome explanation... learning orgo was never such easier... thanks a lot.. great work😃😃
@Leah4sci
7 жыл бұрын
Glad it helped!
Thanks for explaining this mechanism. It's fascinating!
@Leah4sci
3 жыл бұрын
Glad you liked it!
Maam I am from India. These videos are very useful to me . Thanks to u for uploading these videos.
@shahbaazali1195
7 жыл бұрын
same here, life saver !!
@Leah4sci
5 ай бұрын
You're so welcome!
YOU'RE MAGIC ! thank you for your videos queenn
@Leah4sci
2 жыл бұрын
You're so welcome!
The way you teach is amazing..
@Leah4sci
7 ай бұрын
So happy to help!
you totally saved my life.thank you sooo much.
@Leah4sci
3 жыл бұрын
I'm so glad to help!
Very good video !! Well understood. However, I only wished I saw this video months ago before learning this mechanism by means of a much more difficult way !
@Leah4sci
5 жыл бұрын
Glad the video helped you understand the topic better! You are very much welcome!
so wonderfully explained Leah 💖💖💖💖💖💖💖
@Leah4sci
4 жыл бұрын
Glad you liked it!!
WOW. Ive never thought of using butter as a reagent before. Ill have to try that!
@Leah4sci
7 ай бұрын
:)
thank you so much for this amazing video💕💕 did you explain the topic that follows alkene epoxidation (anti and syn dihydroxylation)?
@Leah4sci
3 ай бұрын
You can find my entire alkene series here: leah4sci.com/alkene-reactions/
Thanks! This has been very helpful.
@Leah4sci
6 ай бұрын
you're very welcome!
Thanks Leah Fisch! Now I have a hope in passing my 1st year of Chem BSc! hahaha
@Leah4sci
5 ай бұрын
You're very welcome!
I have a doubt. Alkenes on oxidation with Baeyer's reagent give us diols as our products. Does this follow the same, or some similar mechanism of alkene epoxidation? This is because in my textbook, alkene epoxidation is omitted and many other reactions are present such as polymerisation, Addition of Sulphuric Acid, Oxidation (as given above) and etc.
@Leah4sci
10 ай бұрын
I'm sorry, but I don't offer tutoring over social media. For help with questions like this and more, I recommend joining the organic chemistry study hall. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/
You saved the day for me # Thank you Leah
@Leah4sci
4 жыл бұрын
Awesome! You're very welcome!
Excellent explanation
@Leah4sci
6 жыл бұрын
Glad you enjoyed it!
Mam can you please upload or tell me if you have uploaded video for diels alder reaction??
@Leah4sci
11 ай бұрын
I have a short series on the Diels Alder Reaction that you can find at leah4sci.com/diels-alder-reaction-mechanism-organic-chemistry/
Did you ever make a video on how to open an epoxide? (like what you do in anti-dihydroxylation)
@Leah4sci
2 жыл бұрын
I have not made a KZread video on epoxide ring-opening reactions, but you can find this and more in my Organic Chemistry Study Hall. I recommend joining to dive deep into this reaction and others. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/
Well summarized
@Leah4sci
Жыл бұрын
Glad you liked it, thanks for watching!
Your vids help a loooot
@Leah4sci
2 жыл бұрын
Glad to hear that!
Will this apply to sharpless asymmetric epoxidation
@Leah4sci
6 жыл бұрын
I'm not familiar enough with that reaction to answer your question.
i want the free book how can i get the book ?
@Leah4sci
2 ай бұрын
You can sign up here: leah4sci.com/orgosecrets
Very helpful. Thank you
@Leah4sci
5 жыл бұрын
You're welcome! Glad to help! :)
This is a dumb question but at 5:18 why would alkene break its pi bond and use its electrons to attack oxygen?
@Leah4sci
2 ай бұрын
no question is a dumb question, you ask so you can learn. The pi bond is nucleophilic and while it appears happy, it can easily be enticed to break and attack an electrophile. In the case of oxgyen, because the O-O is very weak and unstable, it's very reactive. (the oxidation number of a peroxide is only -1 making it more susceptible to be attacked compared to the happy -2 oxygen)
@svnspell6709
2 ай бұрын
Thankyou!♡
That is great video ♥️
@Leah4sci
3 жыл бұрын
Thank you!!
how would one go from trans alkene to cis epoxide? or cis alkene to trans epoxide?
@Leah4sci
2 жыл бұрын
flip the alkene first (dihalide -> alkyne -> partial reduction)
Quality teaching mam amazing
@Leah4sci
4 жыл бұрын
Aww thanks!
thank you Leah!
@Leah4sci
4 жыл бұрын
You're very welcome!
you are great thanks
@Leah4sci
5 ай бұрын
You're very welcome!
are you the person who made Fischer projections??
@Leah4sci
6 ай бұрын
lol, nope!
Thank you
@Leah4sci
4 жыл бұрын
You're welcome!
thank you!
@Leah4sci
5 ай бұрын
You're very welcome!
thanks
@Leah4sci
7 ай бұрын
You're welcome
Thank youu💕💕💕
@Leah4sci
4 жыл бұрын
You're welcome!
Why does this reaction start? Why does the pi bond attack the oxygen with two lone pairs already? What makes that oxygen electrophilic?
@minjungkim3144
7 жыл бұрын
it also looks strange to me.
@aman-tl9gd
6 жыл бұрын
unstability of peroxy acid is driving force of mechanism .
@itsdwish
6 жыл бұрын
So I understand that peroxy acid and it's instability is the driving force of the mechanism, but I don't understand (as the original question asks) why her first step is the pi bond attacking an oxygen. Can anyone elaborate?
@aaronholder6294
6 жыл бұрын
the oxygen isn't the electrophile, in this case, the oxygen is slightly negative because it draws the electrons from the hydrogen atom closer to itself making it slightly more reactive than the adjacent oxygen which is attached to a carbon (an electron donating group). The pi bond, on the other hand, is electrophilic in this case (since carbon prefers to have all single bonds instead of sharing electrons). as a result, the (electrophilic) pi bond attacks the unstable electron rich to try to saturate itself. when it does this the electrons from the pi-bond between the carbons move to attack the oxygen and as a result, leaves the adjacent carbon electron deficient with a positive charge. The oxygen, still being electron rich then attacks this positive charge and gives up its proton to help stabilize the charge (if it held onto the hydrogen it would have a + formal charge and would still need to get rid of the hydrogen somehow ).
@datumclasses6245
6 жыл бұрын
actually this can be understood by HOMO LUMO concept.
very good
@Leah4sci
7 ай бұрын
Thanks
i can't thank u enough
@Leah4sci
3 жыл бұрын
You're so welcome!
thanksssss!!!!!
@Leah4sci
6 ай бұрын
You're so welcome!
Anti or syna addition
@Leah4sci
2 жыл бұрын
Epoxides are very tight rings and cannot exist anti
Wow👌👌👌👍👍
@Leah4sci
3 жыл бұрын
😊
thnksssss
@Leah4sci
7 жыл бұрын
welcome
thanks a lot .do you have email please
@Leah4sci
7 жыл бұрын
This is probably too late, but you can contact me here: leah4sci.com/contact/
goddess!!
@Leah4sci
6 жыл бұрын
Thanks?
will u marry me plz
@Leah4sci
6 жыл бұрын
Umm...how about we keep our relationship professional?
Thank you
@Leah4sci
6 жыл бұрын
You are very welcome!