At 14:48 you did a synthesis question where you have used SO3, H2SO4 and then HNO3, H2SO4. Wouldnt the sulfuric acid in the nitric acid act in a way to remove the SO3 on your benzene (unwanted side reaction)? If not, then I noticed that later on you use dilute sulfuric acid to remove SO3 so sounds like that might occur.

Thank you again !!

@ChadsPrep

3 жыл бұрын

You are welcome, Erik!

Fantastic thanks man!

@ChadsPrep

7 ай бұрын

You're welcome and Thank You.

Best professor ever!

@ChadsPrep

Жыл бұрын

Thanks!

Oh Chad!!!I owe you a million when i get a job!🥰

@ChadsPrep

3 ай бұрын

Woo woo! All the best in your future employment endeavors!

5:00 won't the carbocation rearrange since this is alkylation not acylation?

@Patriots4890

9 ай бұрын

it is a primary chlorine therefore there wouldn't be any rearrangement

Great 😍

@ChadsPrep

2 жыл бұрын

Thx!

Why does’t the sulfonate group block the acylation from happening at 3:52 ?

@ChadsPrep

2 жыл бұрын

Hey SP! The para position is blocked by the sulfonate which is why it directs ortho

@s.p.8508

2 жыл бұрын

@@ChadsPrep but doesn’t a sulfonate group block additional friedel-crafts reactions from happening?

@ChadsPrep

2 жыл бұрын

@@s.p.8508 Hello S.P.! You might very well be right. Friedel-Crafts reactions don't work on strongly deactivated rings. If the only substituent were the sulfonate group then you could conclude that the reaction wouldn't be possible. But the alkyl group is an activating group and likely counters the deactivating nature of the sulfonate group. But then you can factor in some steric issues. Acyl groups are large and here we're trying to force it to go ortho to an alkyl group. So now we have a confluence of factors which lead us to believe that the yield might not be as good as we'd like if we were to perform this reaction in the lab. You've convinced me to use a different example for the next go around of the ochem playlist (probably a couple years away). Thanks!

@s.p.8508

2 жыл бұрын

@@ChadsPrep alright, thank you!