Which TKI is Best for Me? / CML / TKI / Chronic Myeloid Leukemia / Tyrosine Kinase Inhibitor

Which TKI is best for me and my pre-existing conditions? In this video we discuss the which TKIs might help or negatively impact different pre-existing conditions.
0:00 Start
0:19 First-Line Treatment TKIs
0:40 Later-Line Treatment TKIs
1:02 Which TKI is best for you?
2:11 Pre-existing conditions
2:53 Stephen's story
#chronicmyeloidleukemia #cml #leukemiasurvivor #tki

Пікірлер: 32

  • @verdeleonais2010
    @verdeleonais20106 ай бұрын

    I’ve been taking my treatment since 2 months and started imatinib mesylate 400g i hope I’ll recover from my cml soon and without ani issues

  • @healCML

    @healCML

    6 ай бұрын

    Best wishes to you and for your healing! Thanks for subscribing and for commenting.

  • @ruchisingh1723

    @ruchisingh1723

    3 күн бұрын

    God bless u❤

  • @RajendraKumar-ef4en
    @RajendraKumar-ef4en6 ай бұрын

    Abl copy number-120157. Bcr/abl (major p210)copy number- less than detectable timits

  • @RajendraKumar-ef4en

    @RajendraKumar-ef4en

    6 ай бұрын

    International scale conversion fector- 1.25.

  • @RajendraKumar-ef4en

    @RajendraKumar-ef4en

    6 ай бұрын

    International scale normalized copy number (%) - less than detectable limit

  • @RajendraKumar-ef4en

    @RajendraKumar-ef4en

    6 ай бұрын

    What is mean of international scale conversion factor 1.25 ?

  • @RajendraKumar-ef4en

    @RajendraKumar-ef4en

    6 ай бұрын

    Plz tell me about international scale conversion fector

  • @ruchisingh1723
    @ruchisingh17233 күн бұрын

    My husband is taking tasigna since last four n half years his rtpcr was undetectable last time but again its 0.03 after six months i m very much worried please reply asap

  • @healCML

    @healCML

    Күн бұрын

    I would wait for another PCR test. Usually it would need to go up to 0.10 before doctor's would look to make a change.

  • @yamgarcia9045
    @yamgarcia90455 ай бұрын

    im taking now sprycel

  • @abhishekrawat6250
    @abhishekrawat62506 ай бұрын

    Taking Nilotinib 300mg twice daily from past one year, first i got alteration in liver enzymes after 6months, then hyperlipidemia, and now liver issue is resolve and lipid profiles are in control. But here a new thing arise called thyroid, now my TSH levels showing high from last 3months. Is this all because of the side effects of the medicines??? As i do not had any of these issues earlier before diagnoses and treatment. My bcr-abl is 0.004 now but still having other issues as i mentioned above.

  • @healCML

    @healCML

    6 ай бұрын

    Thank you for your comment. It is possible for the TSH to increase with a TKI. Mine went up over the years and has gone up even more since I stopped taking the drug. I would ask your doctor to also run a T3 and T4 test. If those are normal, then you might not need to do anything else right now for the increasing TSH.

  • @abhishekrawat6250

    @abhishekrawat6250

    6 ай бұрын

    @@healCML my T3 and T4 are in normal range but only TSH is high. And doctor prescribed me to take Thyroid medicine. For 3 months

  • @abhishekrawat6250

    @abhishekrawat6250

    6 ай бұрын

    ​@@healCML Should I stopped taking tasigna??? And for how long after I have to stopped after asking doctor.

  • @healCML

    @healCML

    6 ай бұрын

    @@abhishekrawat6250 I would only stop the tasigna if you doctor tells you to.

  • @abhishekrawat6250

    @abhishekrawat6250

    6 ай бұрын

    @@healCML after a year of tasigna bcr-abl is 0.004 is good or average?

  • @madhusudanaachar4909
    @madhusudanaachar49096 ай бұрын

    Is imatinib best tki??

  • @healCML

    @healCML

    6 ай бұрын

    Imatinib is a very good TKI. Every body and every situation is different, so it is not easy to say that one TKI is the best.

  • @RajendraKumar-ef4en
    @RajendraKumar-ef4en6 ай бұрын

    Hi

  • @RajendraKumar-ef4en

    @RajendraKumar-ef4en

    6 ай бұрын

    Plz tell me about international scale conversion factor 1.25

  • @RajendraKumar-ef4en
    @RajendraKumar-ef4en6 ай бұрын

    Plz tell me about my abl bcr report

  • @healCML

    @healCML

    6 ай бұрын

    The way I read it, there is no bcr-abl detected in the test, which is very good!

  • @RajendraKumar-ef4en

    @RajendraKumar-ef4en

    6 ай бұрын

    @@healCML can I take imetnib

  • @healCML

    @healCML

    6 ай бұрын

    @@RajendraKumar-ef4en What does your doctor suggest you do?

  • @RajendraKumar-ef4en

    @RajendraKumar-ef4en

    6 ай бұрын

    Plz tell me about international scale conversion factor 1.2

  • @healCML

    @healCML

    5 ай бұрын

    @@RajendraKumar-ef4en Not every lab uses the same criteria for calculating the bcr-abl. So this conversion takes your number and makes it comparable to a scale that is used at many other labs.