What Happens When Two Different Blood Types are Mixed Together?
Ғылым және технология
Blood is packed with red blood cells.
Even though all human blood might look the same, there are actually different kinds called blood types.
Blood types are based on special markers on the surface of red blood cells. These markers, known as antigens, are made from sugars, proteins, and other molecules, and everyone has their own unique set.
There are several systems used to classify blood types...
The best-known are the ABO and Rh blood types, which are very important when it comes to safely giving someone a blood transfusion.
Today, we took a closer look under a microscope to see what happens when we mix blood from different ABO blood types!
#bloodtype #microscope #science
Пікірлер: 721
why did you kidnap your friend and steal his blood?!
@San-lh8us
Ай бұрын
sounds like what a vampire would do
@beethao9380
Ай бұрын
vampire thats why
@ashertan8861
Ай бұрын
Now I know
@vbcbsrnkk8029
Ай бұрын
They are not friends. They are “friends”, whom prefer to get lock up in his basement “willingly”
@jeanackle
Ай бұрын
For "science". 😀
I have type AB, my phone have type C
@_Gusza
Ай бұрын
LMAO
@c.jishnu378
Ай бұрын
69th like.
@paranaenselol
Ай бұрын
As$ and buns: Ab
@user-nw6rx1mu6c
Ай бұрын
Omg I also have Ab blood tooo💅💅💅✨✨✨✨✨✨✨🥴
@ezeke959
Ай бұрын
My mom's bloodbtype is type micro-USB
red blood cells were harmed in the making of this video
@RedPhoenix550
Ай бұрын
Also his friend
@neinten2062
Ай бұрын
@@RedPhoenix550 fr lmao
@Rainbow.Layla.SS1278
9 күн бұрын
His friend be like: ow dude why you do stupid experiments Him: science
@icetyper3353
9 күн бұрын
@@Rainbow.Layla.SS1278 I've accidentally read "Science" as a "Silence!" 😂😂😂
@Rainbow.Layla.SS1278
9 күн бұрын
@@icetyper3353 i mean is fine when i typing the comment i almost messed up
Few* humans were hurt in the making of this video
I’m a B+, and my mother is a B-. We had an RH incompatibility, and my mother was given a tiny bit of my blood and some sort of medication in an IV in order to ensure that if she had any more babies, neither she nor they would be affected by RH Incompatibility. I’m sure that doctors do something more modern (or at least less bloody) now. I was born in the dark ages, otherwise known as the 70’s.
@foreverswiftie
Ай бұрын
That condition is called Erythroblastosis Foetalis
@Kristen242008
Ай бұрын
I am O- and my husband is O+. I had to get a rhogam shot while I was pregnant with our 2 kids, just incase they had my husbands blood type. They both got my blood type though.
@danielcarlsen9228
Ай бұрын
@G0L_D_Fsh Because if the child was O+ and some fetal blood leaked over the placenta, it would cause immunization in the mother resulting in antibodies that could pass back through the placenta and target the blood of the child which would be dangerous. The drug hides the surface marker on the fetal red blood cells thus immunzation does not occur.
@mikepeterjack2132
Ай бұрын
@G0L_D_Fsh because there is blood transfer between mother and child in the body and i think in this case there was a chance they were incompatible or something
@foreverswiftie
Ай бұрын
@G0L_D_Fsh in case of father being (-) and mother being (+), no complications are observed. But in case of mother being (-) and father being (+) and foetus (child) being (+), some of the blood (or antigens) mix with the mother's blood and she becomes sensitized. In subsequent conception, in absence of Rhogum inj. The foetus RBC is destroyed causing Jaundice and such
0:18 He sanitize his index finger but then prick his middle finger one 😭😭😭
@AbelJo-fj6ud
4 күн бұрын
Bruhh, i js notice it
It’s so cool how red blood cells literally are donut shaped.
@narmowolf4201
Ай бұрын
True 😂 only healthy red blood cells though, for example for people who have sickle cell anemia their red blood cells are a sickle shape (like a Cresent moon if you don't know farming tools lol)
@San-lh8us
Ай бұрын
yes, _delicious donuts_ 🧛♂
@cloudfish1829
Ай бұрын
Frr little floatie rings
@meowrbius
Ай бұрын
Hence proved Earth is a donut.
@phs125
Ай бұрын
He literally showed diagrams and videos of RBCs!!!! It's NOT donut shaped. It's flat disk shaped, with thin centres
0:22 Didn't sound as if you "lightly" pricked your finger
@T1tan_Spe4ker_M4n
Ай бұрын
Fr😅
@sweetzuko
Ай бұрын
yea...
@narmowolf4201
Ай бұрын
"Lightly" pricking your finger can still hurt a lot. Sometimes it doesn't hurt too much but also tends to bleed less then too - source: I'm diabetic and have to prick my fingers to test my blood sugar far too many times every day 😅
@gaygoddessnamedmadoka2252
Ай бұрын
those things hurts a lot so it's understandable
@Koutouhara
Ай бұрын
@@narmowolf4201 for real.. sugar problems run in my family and I tend to run hypoglycemic (low) so i have to check mine when I'm feeling off. The tester I use is loud when clicked only because it's the spring-mechanism is cheap, but the pain isn't so much related to the sound, just the needle being cheap/blunt since I got the cheaper brand. My grandmother's which is way more expensive didn't hurt as much when I've had to use theirs in a pinch. She's diabetic so needs to track hers more often ^^
he put his blood, sweat and tears in this video
@chaken6187
17 күн бұрын
Not only “his”
Few droplets of blood dropped to create this video
@c.jishnu378
Ай бұрын
I am replying to make this the top comment.
@Thelengendaryduoling
Ай бұрын
I am the 100th like
@joyishankujurkujurjoykujur2737
Ай бұрын
bump
@Fatipapi
11 күн бұрын
the forbidden cereal
Never ever punch the fingertips (full of nerve endings and very painful) but on the sides, for a drop of blood. Word of a diabetic! 😂
@kme
19 күн бұрын
Really? Nobody told me that. (newly diagnosed) My fingertips always freaking hurt when I do the testing bc nobody's shown me how to do it or what I'm supposed to be doing at all. *very frustrated*
@Mr.Cockney
19 күн бұрын
@@kme Give it a try and tell me!
@kme
19 күн бұрын
@@Mr.Cockney I will, thx. I always struggle to get anything out of my fingertips too. I usually have to do it 2-3x before I get anything out. It's very painful and frustrating. I might go to a different dr and see if they can help me with everything, bc my current GP isn't really supporting me. Idk wtf I'm doing, basically.
@Mr.Cockney
19 күн бұрын
@@kme I agree. Moreover, perhaps your struggle to obtain a drop of blood is related to this. Because it is very painful to poke the fingertips you also give not enough value to the device with the needle and thus the lack of blood. But if you hit the side of the finger you can use more penetration achieving both more blood and less tries.
@kme
19 күн бұрын
@@Mr.Cockney makes sense. Thanks 👍
Type O is universal for blood. While AB can only take from others in blood. However, AB plasma can be given to any other type. Its the opposite for plasma.
@surecom12
Ай бұрын
Yeah, they're basically vampires 🤣
@nayhem
Ай бұрын
Yet another video that disregards plasma (which is carrying the antibodies if present) and focuses almost entirely on the blood cells.
@iranalmonte
28 күн бұрын
@@nayhemwhat’s wrong with that? Maybe they’ll make a video teaching people of components and plasma
@ontheedge91
17 күн бұрын
O- is universal. O+ is only usable in positive blood types.
@yumeno-w-
17 күн бұрын
plasma ?!?!! :0 ive never ever even heard abt dis..
That’s a weird fish
@Xavus-137
Ай бұрын
It keeps getting weird by every vid
I'm a blood type O but I kinda hate it for the reason mosquitos like to follow me around and suck my blood. I have a lot of mosquito bites and scratches due to it. (Mosquitos loves Blood Type O. For them, it's a delicacy LOL)
@AlfaLyr
16 күн бұрын
On the other side, the fact that we have A and B antibodies protects us from some stuff! For example, type 0 get malaria much more mildly than type A
@nominae
14 күн бұрын
It’s the opposite for me. My friends were bitten badly by mosquitoes (while visiting a hot springs) but I was never bitten once. And then I thought the mosquitoes must hate my O blood type 😂
@Pi4ever
11 күн бұрын
@@nominaeBecause even though a study showed mosquitoes preferred the O blood type when given the choice of it and A blood type, there was no exact correlation between blood type and their attraction. There's also the factor that O+ blood is the most common worldwide, so more people will relate to getting bitten by mosquitoes and sometimes associate with their blood type. Obs: I live in Brazil, tropical country with a lot of mosquitoes and I barely get bitten by then, even when my house - on summer - got swarmed with them.
@I.no.ah.guy57
11 күн бұрын
I'm O positive too and I always get eaten alive in the summer whenever I go outside lol
@veljkopavlovic607
9 күн бұрын
I'm type O- and mosquitoes avoid me, rather massacring others around me
Isnt anybody gonna talk about those demomic screams in the back?? 1:48
@polskus
Ай бұрын
Just his "volunteering" friend's sounds of joy!!!
@Archetype996
8 күн бұрын
😂
2:44 😂 the friend sounds like angry with a "chha!!!"
@TotallyYulia
14 күн бұрын
No he screamed fuck
The blood type personality test really took off in Japan, and it is even more popular than something like a zodiac sign is here. If you sign up on any dating app in Japan, it asks your blood type for this reason. Though like zodiacs, it seems to be something that only a small group of mostly women take at all seriously and everyone else sees as just a bit of fun.
@The-Devils-Advocate
Ай бұрын
At least knowing blood type is useful
@HyperVanilo
Ай бұрын
Even game characters has blood type, as if we can save our favorite character's life by donating our blood to them
@user-xm7uw6uc7g
Ай бұрын
@@HyperVanilo what?
@rebecca_rh
Ай бұрын
Ironically enough, there actually might be a scientific explanation behind the people with blood type O (supposedly) being gentler. Type O is the blood type of the original humans, the oldest one. Antrophologists have found evidence that when we were hunter gatherers, we were more egalitarian and gentler in general. With the rise of agriculture around 10 000 years ago, some people started accumulating more wealth than others and used that to have control over other people. the concept of authority and people ruling over others, as well as money and warfare, was born there. The diets changed as well as we started eating more grains, and the blood with it. And we started becoming generally more violent as well. It wouldn’t surprise me if people with type O blood also retained other genes from our gentler ancestors. (This is still mostly speculation tough so take it with a grain of salt)
@rebecca_rh
Ай бұрын
Ironically enough, there actually might be a scientific explanation behind the people with blood type O (supposedly) being gentler. Type O is the blood type of the original humans, the oldest one. (That’s also the reason why it can be donated to anyone and doesn’t have specific antigens, it’s the least specialized one!) Antrophologists have found evidence that when we were hunter gatherers, we were more egalitarian and gentler in general. With the rise of agriculture around 10 000 years ago, some people started accumulating more wealth than others and used that to have control over other people. the concept of authority and people ruling over others, as well as money and warfare, was born there. The diets changed as well as we started eating more grains, and the blood with it. And we started becoming generally more violent as well. It wouldn’t surprise me if people with type O blood also retained other genes from our gentler ancestors. (This is still mostly speculation tough so take it with a grain of salt)
Although O blood type is considered the universal donor, there is a much more universal dinor than O blood type and that is rh null. That blood type is devoid of any antigen that it can donate on both rh positive and rh negative blood type....
@maleficent3333
Ай бұрын
I have AB , universal taker of blood, :D
@SharkBabySeal
Ай бұрын
Same im ab-
@mariuszmoraw3571
Ай бұрын
Wasn't 0- basically "null"? As in wasn't +/- indicative of some sex-related anti-gen where one was active vs not? (And if I remember pretty much the first thing you check when dealing with constant child loss during pregnancy)
@atarashi8513
Ай бұрын
Is there an anti blood cell?
@green2332
Ай бұрын
@@mariuszmoraw3571 Nah he is reffering to an extremely rare type where only couple people in the world have it. Rh blood group has if i remember 18 phenotypes where half of them are positive, half of them are negative. An example would be D+ C+ E− c+ e+ type that is most common. Rh null doesnt have them at all
I started shivering when you prickled your finger omg😭😭
When you didn't study for the test and it says you are +A
@mariuszmoraw3571
Ай бұрын
"Bro... It's your blood test" "You just say it cause you got 0-. Ha!" 😂
2:50 Isn't type O universal donor, so shouldn't that be the reason that you didn't see much of a reaction
@sumbody207
Ай бұрын
But there was. He didn’t specify whether either blood was negative or positive. people with O- blood are universal donors whereas O+ blood are only compatible with other positive blood (A+, B+ or AB+). So what we might be seeing is a B- blood reacting with a O+ blood.
@n-steam
Ай бұрын
O-type blood contains anti-A and anti-B antibodies in the plasma. What you're seeing is the anti-B antibodies in the O-type plasma reacting with the B-type red blood cells. O- is a universal donor, in that it can donate RBCs to anyone. But it should be separated out before transfusing for no reaction to occur.
@Robert_PottyPants
Ай бұрын
O type is universal donor, not acceptor. @@n-steam is right
@iranalmonte
28 күн бұрын
So basically we have whole blood which is broken down into 4 components: 1. Red Blood Cells 2. Plasma 3. Platelets 4. Cryoprecipitate To keep it simple, type O IS the universal donor. But this only applies to type O red cells. As another comment stated, the reason you saw the reaction was because he mixed whole blood not just red cells. This means that the antibodies in the Type O plasma reacted with the Type B red cells. Hope that helps !
@angeladavies993
24 күн бұрын
O neg is a universal donor. As a 13yrold, I'm 72 now, my parents and siblings were asked to give blood when they were researching blood for the rhesus factor. We are all the same O neg which we wer told was unusual. My aunt was working for the team at Liverpool University doing the research and volunteered us!
A+B/AB+A/AB+B=team death match O+any=teamup
@somedudefromapharmacy
Ай бұрын
O blood type is not loyal to a country nor flag.
@iknow007
Ай бұрын
@@somedudefromapharmacy mercenary
@Laerei
Ай бұрын
@@somedudefromapharmacy More like type O is free real estate
@somedudefromapharmacy
Ай бұрын
@@Laerei makes more sense
Is it me, or the part in 2:23 looks like planet earth😂 ?
@Lostouille
7 күн бұрын
That s you 💀
I learn more by watching KZread and especially read the comments than my entire school years + college combine 😅 love all the information sharing
Underrated channel fr, keep it up
Also, ABO antibodies (anti-A, anti-B) are formed naturally after being born. Rh antibodies (anti-D) are formed via exposicion like; transfusions or pregnancy (the mother). Just wanted to share what was tought to me recently. Love the video.
@hangezoeSNK
Ай бұрын
can you explain it a bit more? I like learning about biology :)
@mati.benapezo
Ай бұрын
Someone who recieved blood transfusion from a donor with a non compatible blood type, especifically the less common ones (low frecuency or non ABO) can develop antibodies from that, and then it gets harder for that person to receive any blood. Even if they share the same ABO group.
@iranalmonte
28 күн бұрын
@@hangezoeSNK so basically we have many antibodies which our immune system makes to help us survive :). They are separated into different classes of antibodies based on their structure. So when we are born we are given genes from our parents. This includes our blood type. Everybody has a blood type; A, B, O or AB. This is the ABO system. It is the biggest blood system we know, and the most immunogenic meaning it causes us the most harm if there is incompatibility between the blood types. In our plasma we have antibodies to the other blood types that we DO NOT have. This occurs naturally from the day you are born you are predisposed to having those antibodies in your blood. There is nothing that we can do to change that. These antibodies are class IgM. We also have the 2nd most immunogenic blood system called the Rh system. This determines whether we have a + or - beside our blood type. If we have a positive beside our blood type this means we have the antigen (A+, B+, O+, AB+). If we have a - beside our blood type then we DO NOT have the antigen and are at risk of making the antibody. We do NOT naturally have this antibody in our system, meaning we have to be exposed to it to get it. We can get it through 2 ways, pregnancy or transfusion. This antibody is class IgG and CAN cross the placenta and hurt our babies. Hope that helps :)
@celticphoenix2579
15 күн бұрын
Really? So if the mom has Rh+ wouldn't she have only Rh+ babies? I'm trying to figure out how I came out Rh- from a mom who is Rh+ 🤔
@mati.benapezo
15 күн бұрын
@@celticphoenix2579 It's possible that your dad was Rh -.
So it means type AB has the most highest survivality in war and accidents as they are compatible to take in any blood type while type O is the one suffering.
@reallyreallylazy1458
Ай бұрын
it still depends on the major histocompatibility test, or even the minor histocompatibility test
@accuracyadherent556
27 күн бұрын
Doubt it. The body can tolerate a little amounts of different blood types. If you have lost a lot of blood, you need your own type. And AB is a rarest one.
2 people was harmed in the making of this video.
His friend really enjoyed the blood 💀
It's the screams when getting pricked. 🤣🤣
@tiffanydominguez2515
19 күн бұрын
Video ahh. You:AHHHAAAAAHAAAAHAHAHAHHAHAHAHAHAHAHAHAHAHAHA
These are exactly the kind of videos and knowledge we viewers deserve on KZread
Yeah, don't know about this thing claiming the Type O people to be more gentle, but I am type O and when I first heard about it and being an universal donor, I got really happy to be able to help someone
that's one wierd fish
0:29 There comes the logo
hey! i love your channel i think its interesting and cool, i hope u would post more so i can watch them all!❤
I think mosquitos like type O blood cause they won’t get an upset tummy no matter what they had for lunch.
Now do a follow up on the RH factor...
@NNRedemption
13 күн бұрын
And Then the Other 41 classifications Like Duffy
I like how you censored the mixed blood on the thumbnail like it's a spoiler and not just a regular blood spot that all look the same
basically the blood goes into a cellular domestic violence altercation and a battle ensues until the last red corpuscle isn't standing. Taps plays 🎺
Since you mixed type O with type B, isn't it normal that there was little to no reaction visible under the microscope? I don't think it was because of the concentration of the antigens in blood vs in testing solution, but more that Type O doesn't have any antigens, so there's nothing for type B cells to react with. If you had a type A friend laying around and mixed his blood sample with type B friend's, you could probably have obtained a much more pronounced reaction.
@souleymanesaid3968
Ай бұрын
Yes, that make sense
@danielcarlsen9228
Ай бұрын
But type O blood contains antibodies against both A and B antigens? Or is that only if you have been immunized? Blood bags are cleared of antibodies but here it is fresh blood?
@littleleo7072
Ай бұрын
@@danielcarlsen9228 exactly what I thought
@danielcarlsen9228
Ай бұрын
@@littleleo7072 Yeah, so if you give B-type blood to a O-type patient it will end badly.
@nekomatafuyu
Ай бұрын
@@danielcarlsen9228 If I recall correctly, you will have small amounts of antibodies in your blood for antigen you don't have, but your body doesn't ramp up production of these antibodies until the foreign antigen is detected. Kurzgesagt did a superb book on the subject that I thoroughly recommend picking up.
Just causally stealing blood from a friend
great video!
Type O is a Universal Donor but we can’t accept any from those we had been given 😢
this has the vibe of a 2014 video
I am an O+ blood donor and i do donate my blood thrice in a year. 😊✌️
Fishy: After "lightly" pricking my finger.. AAAHHH- PFF that one cracked me up. And that poor friend...
My Hemophobia getting wild 😂
I've done a type specific walking donor transfusion without cross match in the military on deployment. I was 100% prepared to respond to a reaction even though they were both B+. There are other antigens that can cause deadly reactions. And when you're transporting a critically wounded patient at 35,000 foot altitude over the ocean, you're the only response they will get for hours. You better be ready for it.
@iranalmonte
28 күн бұрын
Thank you for your service
@Absaalookemensch
28 күн бұрын
@@iranalmonte My honor giving back to my adopted country.
Nah man your friend is the GOAT for letting you prick his finger
Hello, what is that microscope your using? I am very interested in science and also astronomy, I really want to have a microscope that can see bacterias, things and others.
4:30 There is a chart of which blood type, including the rhesus factor, are compatible to each other. I think the video should have included mentioning the rhesus factor compatibility too or even shown that chart. I would have prefered that information over the "blood personality"-bit, tbh. Other than that, it was a good approach on giving an easy understanding about that topic.
A portal the underworld opens.
That goofy sound effect felt like I was watching Tom and Jerry.
What i'm getting from this is that if i get hurt i can use the blood of my enemies to close the wounds faster
0:22 Augh 😫
This is very interesting Can you maybe try and show what happens if the blood of different species is mixed together?
I FELT SAD FOR YOUR FRIEND
Think what will happen with People with rare blood group💀💀💀.
The thing about type o blood is that mosquitoes bite type o blood more than a and b blood and I have o blood so it can get annoying trying to go outside
I did blood typing for my Phlebotomy class. It was fun haha
"Pricking myself lightly" "AAAAAAAAAAAAAAAUUUUUUUUGGGGGGGGGHHHHHHH" you know your friends are real when they let you steal their internal juice box
...can you change blood type if your give enough blood?
I knew he was secretly a vampire
My new favorite kind of fish :)
The blood type o personality thing was probably made to peer pressure them into donating blood, huh?
Lacking a proper testing set-up, would you say that the reaction is strong enough that you can determine compatibility just by mixing the blood of two different people together and seeing what happens or would you need a microscope? Would be interesting for a novel idea where the characters don't have access to the necessary facilities to do proper testing.
Makes you wonder how often transfusions were performed before testing for these factors were widespread; did any olden times blogs giving (not letting) occur? It'll be such a shame when the cataclysm happens and we lose technology to where blood loss will be even more critical and hard to fix for any survivors :(
Bros friend was fighting for his life
I'm 33 years old and still waiting for a tube to look as comfy as a red blood cell
actually seen and learned something new Thanks fishy Science
Was the script missing the inclusion of a test against type A antigen for your friend's blood? It looked like the slide might have also had the type A antigen with a negative result, and the script kinda hints at it, but never explicitly mentions the negative result for type A.
i'm terrified of his friend's scream
I love how we have a “self destruct” button triggered when another person’s blood enters our bloodstream
2:59 Never seen a wet mount preparation using a flooding amount of liquid to cover glass💀
i hate those pins 😂 its so small and so painful and funny at the same time.
that screams !💀 Im felt bad for your friends. ⚰️💀
3:00 looks like a blood puzzle piece
I learned if you get a different blood type in yours you can feel like you're dying or dead
as an o blood haver, im afraid of getting into an accident
Why do red blood cells look like gummys
@aaronnoriega9737
Ай бұрын
Because they are
**Trillions of Blood Cells were harmed in this video**
Dang, incredible.
I have a question what does the blood type O+ do?
tldw: you get type d (the d stands for death)
@DerErbseneintopf
Ай бұрын
Glad you clarified 🤭
POV:where all your donated blood goes
Would you do a Termite Queen dissection? I really want to see why its belly is moving so much.
Proud type O here 😎😆
Now how about positive and negative blood types? How do you test for that?
And here i thought the mix of many blood can make some sort of reaction, imagining it has power to become new source of energy 😅
Wonder what hiv looks like under microscope also mixing hiv with normal blood under microscope
@AmyEugene
Ай бұрын
HIV can reduce white blood cell counts but I don't think it impacts the number of red blood cells or their appearance. To see HIV, you need an electron microscope. There are colorized 3D electron microscope images online.
I remember being told I’ve got a good blood type for donation, it’s O- if I remember right
This is why you must be careful on blood transfusions
I'm O- We had to do our own blood type test in Biology. Ended up having to have a classmate prick each other because we were all chickens.
No Cells at work, harm in this video.
bro becomes his lab mouse 💀
As Fishy began experimenting. He proceeds to ask the red blood cells "are you mixable because you have different blood types,or you have different blood types because you are mixable" The the red blood cells then said "Nah we'd clump"
"only a small amount can be given" but why only a small amount couldn't you give as much as you want if they are the same blood type?
Bro is a 😊chad for giving his own blood just for content
A friendly ebay Agent 47 with type O blood...
I'm a bit confused. I didn't expect mixing O with any blood would cause any reaction. Does it clump only slightly when compared with mixing say, A B samples?