What are the Catecholamines? | Dopamine, Norepinephrine, Epinephrine | Physiology and Main Functions
The 3 catecholamines are Dopamine, Norepinephrine, and Epinephrine.
The process for synthesizing catecholamines is:
Digest a protein source containing phenylalanine (an essential amino acid)
Phenylalanine ➡️ Tyrosine (a nonessential amino acid)
Tyrosine ➡️ L DOPA (aka levodopa)
Levodopa ➡️ Dopamine
Dopamine ➡️ Norepinephrine
Norepinephrine ➡️ Epinephrine
What does Dopamine do?
Dopamine is a neurotransmitter in the brain
Dopamine is involved in reward/ motivation pathways as well as the motor control pathways.
Dopamine is known for it’s role in Parkinson’s disease.
When dopamine producing neurons in the substantial migration die off Parkinson’s disease can result in slowness, rigidity, tremors, and decreased motor control.
Parkinson’s Disease is treated with Levadopa which should make sense since we talked about how it is the precursor to dopamine.
What do epinephrine and norepinephrine do?
Increase blood pressure
Increase muscle contractions via increased calcium release
Increase energy availability
Increase testosterone, growth hormone, IGF-1
Increase vasodilation
Where are the catecholamines synthesized?
The Adrenal Medulla
00:27 Bioenergetic pathway of synthesizing catecholamines
00:46 Phenylalanine
00:48 Tyrosine
00:55 Levadopa
01:15 Catecholamines Epinephrine, Norepinephrine, Dopamine
01:50 Functions of Dopamine
02:12 Role of Dopamine in Parkinson’s Disease
02:34 Functions of Epinephrine and Norepinephrine
03:30 Smash the like button
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Пікірлер: 28
Thank you! I am not a medical professional but a patient that may have a problem with Catecholamines and I needed to understand what they are doing to my body. I’m a lot clearer now 👍🙏☺️
VERY clear video, thank you!
I loved those synthesis process explained simply!
explained simply! Thank you
Your videos are SO WELL DONE my friend. Thanks for helping me learn about these catecholamines!
@TheMovementSystem
3 жыл бұрын
Thank you!
Very good job! Thank you.
Great informational video dude!
Thank you for this I don't understand it all yet so I'm going to re-watch it lots of times to understand more about why I'm craving coffee and coffee has that c word in it. :-)
THANK YOU
Will you do a bioenergetic pathway on each of the nine essential amino acids please??
Thank you for this information
@TheMovementSystem
2 жыл бұрын
You’re welcome
Well explained sir love from India
@TheMovementSystem
3 жыл бұрын
Thank you!
is there any supplements for Catecholamines?
Is prestiq a catecholamine inhibitions? And also prozac?
How do catecholamine supplements interact with methylphenidate?
If someone is deficient in both Eppinette, friend and norepinephrine, should they simply just support this pathway with vitamin C and sam E?
Please answer me! I wonder about epinephrine vs female hormones . And if the testosterone produced from epinephrine,wich my girlfriend finds in the pill wellbutrin,also called ziban or else. Thanks
@TheMovementSystem
2 жыл бұрын
I'm not familiar with that. You'll want to consult with your doctor or endocrinologist
The rings are aromatic as in catechol itself.
dopamine is synthesized in the adrenal medulla...but released from the substantia nigra? How did dopamine get from the medulla cortex to the substantia nigra?
So protein makes you happy?
is it just because I come from medical side that I think saying epi and norepi causes vasodilation is a bit misleading... it causes vasoconstriction in many organ/tissues, but it is true that if only talking about skeletal muscles that it does cause vasodilation especially in big muscles...
@TheMovementSystem
3 жыл бұрын
I’m actually not certain of the details of that.
@NathanYPing
3 жыл бұрын
Medical side ya coz in general epinephrine and norepinephrine can do both vasodilation and vasoconstriction depending on types of adrenergic receptors (alpha or beta adrenergic receptors) Norepinephrine more of vasoconstrictive effects Skeletal muscle shud have more beta2 adrenergic receptors where stimulation of epi or norepi will cause vasodilation in general
Hovno