What Alcohol Does to Your Brain (not good... or is it?)

Ғылым және технология

In this video, Rhonda covers:
(00:00) How alcohol causes brain volume loss
(02:07) Why alcohol might increase levels of iron in the brain
(03:50) How alcohol damages brain cells via acetaldehyde toxicity
(04:07) How alcohol causes neuroinflammation
(05:08) Does alcohol increase dementia & Alzheimer's disease risk
(11:09) Do genetics modify the association between alcohol consumption and cognitive decline risk?
(14:43) Alcohol intake recommendations if you have 1 or more copies of the APOE4 allele
(15:19) Mechanisms responsible for alcohol's effects on Alzheimer's disease & dementia risks
(19:03) Should you drink red wine for the resveratrol?
Learn the truth about alcohol in the full episode:
• The Truth About Alcoho...
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fmfomega3guide.com/

Пікірлер: 137

  • @FoundMyFitnessClips
    @FoundMyFitnessClips25 күн бұрын

    My omega-3 guide on concerns like a-fib, dosage, supplement quality, oxidation, and more: fmfomega3guide.com/

  • @jakecarroll5
    @jakecarroll525 күн бұрын

    Quitting alcohol was a great decision. Its nice always waking up early and feeling refreshed.

  • @bmelvin1234

    @bmelvin1234

    23 күн бұрын

    Amen to that

  • @burnhamsghost8044

    @burnhamsghost8044

    23 күн бұрын

    I mean, how much were you drinking?

  • @jeffreyschmitz8375

    @jeffreyschmitz8375

    11 күн бұрын

    Were you a drunk.

  • @bobmartens1089
    @bobmartens108923 күн бұрын

    I'm 67 healthy and very active and a pretty heavy drinker. But I quit a few mths ago, I like drinking but hate the effects, especially now that I'm older, feel much better and have a better life due to quitting. Plus you save a ton of money.

  • @joeysocks5718
    @joeysocks571825 күн бұрын

    I have a close friend who is 73 and a heavy drinker for decades. Sadly, he acts like someone with serious dementia now. :(

  • @deborahwhit118

    @deborahwhit118

    23 күн бұрын

    They start talking to people who aren't there 😂.FACT

  • @joesacco9832
    @joesacco983225 күн бұрын

    Heavy use causes severe brain damage. Heavy users start as moderate. The addictive potential is often sadly ignored.

  • @AdventureAwaits972
    @AdventureAwaits97225 күн бұрын

    Thank you for all you do to inform the public. I have always been a moderate drinker never more than one drink or less at a social event. I stopped drinking completely around three months ago ... after just a few sips at a happy hour event ... I realized that I did not enjoy the way it made me feel As a carrier of two copies of the APOE4 gene ... this video definitely confirms my decision

  • @skygreen5939
    @skygreen593922 күн бұрын

    Very helpful, appropriately-nuanced, and actionable analysis. Thank you!

  • @ostinspace
    @ostinspace25 күн бұрын

    As soon as I have wine I feel like I need more.

  • @tomdebevoise
    @tomdebevoise25 күн бұрын

    The issue with the UK study is that the alcohol consumption rate was self reported, and it is well known that their numbers are at least 50% lower than actual. You can only conclude that regular alcohol use will reduce Grey and white brain volume.

  • @6048733993

    @6048733993

    25 күн бұрын

    maybe they can't count anymore because of their lack of grey and white brain volume 🤔🤔

  • @fryertuck6496
    @fryertuck649616 күн бұрын

    Im Irish, drank every day of my adult life, apart from an 11 month dry period during which I felt zero difference. Im 59 now and my last IQ test was the same as the first one I ever had at age 19, 129. *Disclosures, I train hard and heavy and eat carnivore. My triglyceride to HDL ratio is 0.8.

  • @user-mv5dt1sc5q
    @user-mv5dt1sc5q25 күн бұрын

    Thank you, you and your contribution to our health and education is greatly appreciated❤

  • @user-gh7yr7tf3r
    @user-gh7yr7tf3r24 күн бұрын

    My anxiety is through roof with moderates amount

  • @jdemarco
    @jdemarco4 күн бұрын

    Enjoying a cold one while watching this...🍺😊

  • @12henry1234
    @12henry123422 күн бұрын

    Thank you.

  • @nickmagrick7702
    @nickmagrick770224 күн бұрын

    Man, Rhonda Patrick really is the fking best. I wish all doctors were at her caliber

  • @winwinmilieudefensie7757
    @winwinmilieudefensie775725 күн бұрын

    Perfect timing 😅

  • @chariotsoffire2714
    @chariotsoffire271423 күн бұрын

    Alcohol makes me light headed. Never realized that was literal!

  • @skye7690
    @skye769023 күн бұрын

    Fascinating video. I never would have thought 1-2 drinks/ day would be beneficial in any way, especially to brain, heart.

  • @burnhamsghost8044

    @burnhamsghost8044

    23 күн бұрын

    You would be wrong I’m assuming studies do not show benefits at that level

  • @derekfrost8991

    @derekfrost8991

    17 күн бұрын

    I brew my own beer. I can feel a big difference with shop bought beer which hits harder and effects last about half as long. I prefer less effect but which lasts longer. Also my yeast is not sterilized which has gut benefits.

  • @SmithyWesson
    @SmithyWesson24 күн бұрын

    Very useful info dr patrick much appreciated

  • @deborahwhit118

    @deborahwhit118

    23 күн бұрын

    Just another perspective 😂

  • @joviankaz
    @joviankaz21 күн бұрын

    People always tend to vastly misjudge the value of the experience that something they interact with has in their lives (ie. Alcohol) by erring on only evaluating one or at most two of the 3 critical phases of existence that an experience yields. The 3 phases to be evaluated include the before, the during and the after. Ie. Whats the cost/facility to obtain/produce the experience. Then what's felt/tasted during the experience (Generally the phase that gets evaluated ignoring the other two and especially the next phase:) And finally the after phase - what's left in the aftermath to feel/experience going forward (this phase specifically is vastly ignored and otherwise understood as it involves both the immediate effects (ie. Hangover) & the longer term effects ie. The widest array of medical and financial and social implications)... unfortunately only the few tend to invest enough thought and attention to look at things deeply enough to be able to really gage the pros/cons of an experience

  • @jonahbert111
    @jonahbert11121 күн бұрын

    These are associative studies. There are likely other important factors that co-associate with low levels of drink, that may account for any positive effects. Alcohol is a toxin at any level.

  • @stevenjbrown101
    @stevenjbrown10123 күн бұрын

    Rhonda saved my life with info from the Rogan podcast. Broccoli sprouts literally stopped me from dying

  • @gabymalembe

    @gabymalembe

    23 күн бұрын

    I grow broccoli microgreens. Takes 10 seconds a day, and 15 cents a week.

  • @travelswithted
    @travelswithted25 күн бұрын

    What about the metabolic effect of drinking alcohol?

  • @localboy2010
    @localboy201025 күн бұрын

    thanks amazing info

  • @InitialDL84
    @InitialDL8415 күн бұрын

    I feel like the older I get, the less I want to drink anything alcoholic. I can literally feel my brain cells deteriorating whenever I drink, feel extremely sluggish, can't focus, lazy, etc. I'm trying to cut down drinking considerably to just a few times a year. If I could go completely sober, I would, but I like having a glass of Macallans or a beer every once in a while.

  • @nickmagrick7702
    @nickmagrick770224 күн бұрын

    Im glad she went into the nuance. I don't think alcohol is strictly bad for you, but its really easy to go past the point where it is useful.

  • @deborahwhit118

    @deborahwhit118

    23 күн бұрын

    Just admit your an alcoholic....step one .

  • @nickmagrick7702

    @nickmagrick7702

    23 күн бұрын

    @@deborahwhit118 I drink less than once a month, I doubt I could be considered an alcoholic by any culture or time periods standard. Maybe in some far flung future a super uptight civilization might consider that an alcoholic.

  • @winwinmilieudefensie7757
    @winwinmilieudefensie775725 күн бұрын

    Is any of it any point reversible?

  • @Shroomunati
    @Shroomunati22 күн бұрын

    your beauty is intoxicating enough

  • @BrandonSL500
    @BrandonSL50025 күн бұрын

    Contradictory information from the studies on APOE and alcohol. Why?

  • @Learnguitartoday
    @Learnguitartoday25 күн бұрын

    how do we find out if we are ApoE4 carriers?

  • @andrewcasini5965
    @andrewcasini596525 күн бұрын

    Rhonda as I recall you are an apoE gene carrier. Curious if you still drink socially now & then for pleasure? Thank you for the excellent summary!

  • @JavierCespedes90
    @JavierCespedes9025 күн бұрын

    The study saying that alcohol helps to reduce dementia seems like total BS.

  • @notgunnadoit7461
    @notgunnadoit74612 күн бұрын

    Why the helm do I like Rhonda so much? She's just awesome. You know what I like? I enjoy a woman speaking scientific truths that's what! No I don't have a crush I know she's marriaged. lol.

  • @Appleblade
    @Appleblade25 күн бұрын

    18:00 Wow. So my 2 beers a day, which I drink late morning, really might not be so bad. lol... They really are the limit for me anyway... 3 beers and I feel sleepy later.

  • @richardlouis1284
    @richardlouis128424 күн бұрын

    Hitchens was a drinker and one of the most brilliant thinkers of our times

  • @anthonyhulse1248

    @anthonyhulse1248

    23 күн бұрын

    That’s debatable. He was voluble and articulate but not always logical or reasonable, or evidence based, and sometimes he was merely childish and vitriolic.

  • @randolphpinkle4482

    @randolphpinkle4482

    23 күн бұрын

    @@anthonyhulse1248 Hitchens was very often an AH.

  • @joe-zp7ge
    @joe-zp7ge25 күн бұрын

    a glass of wine relaxes my brain. im tired of whats supposedly good or bad for my brain. the world is a stressful place and a good chianti or bourbon is wonderful

  • @cocoablini

    @cocoablini

    25 күн бұрын

    Totally. Its a complete shithole out there. You know whats bad for the brain? US politics and media.

  • @leagueofotters2774

    @leagueofotters2774

    25 күн бұрын

    and perhaps some fava beans with that nice chianti?

  • @mrdaggydoochikevscou473

    @mrdaggydoochikevscou473

    25 күн бұрын

    @@leagueofotters2774😂😂

  • @mrdaggydoochikevscou473

    @mrdaggydoochikevscou473

    25 күн бұрын

    @@leagueofotters2774silence of the 🐑s..👌👌🤣

  • @taurusthebull76
    @taurusthebull7623 күн бұрын

    Very interesting 🧐

  • @ZenPepperClub
    @ZenPepperClub24 күн бұрын

    Don't tell huberman about this😂😂😂

  • @mikedock7235
    @mikedock723525 күн бұрын

    Yeah not had a drink in 6 months have lost weight and inches it really is no good for you

  • @willemvanriet7160
    @willemvanriet716024 күн бұрын

    Hard to believe that alcohol can have a protective affect against Alzheimer's. Must be skewed by the advanced age of the participants.

  • @dattajack
    @dattajack20 күн бұрын

    So that's why I'm getting foggier 'just' drinking a tall boy most evenings.

  • @DanCantStandYA
    @DanCantStandYA25 күн бұрын

    I feel like this is information overload. I will continue to drink about once per month and workout 3-5 days week, while also eating health 6 days per week.

  • @phrozen17

    @phrozen17

    25 күн бұрын

    We get it, your a bonehead who can't handle too much information lol

  • @randolphpinkle4482

    @randolphpinkle4482

    23 күн бұрын

    Yes, but don't forget to include the million and one supplements, HIIT workouts, VO2 max workouts, daily mobility exercises, grip strength exercises, yadda yadda yadda. Hell, who has time to drink!

  • @2023Red
    @2023Red21 күн бұрын

    I drink half bottle ultra beer with my dish of walnuts at bedtime. I assume that has to stop accordingly. Is that the message here?

  • @imikewillrockyou
    @imikewillrockyou25 күн бұрын

    Hold on, I need a drink before we dive into this subject.

  • @jjac72
    @jjac7223 күн бұрын

    Everything in moderation. Everything kills you slowly.

  • @schmileyboy
    @schmileyboy25 күн бұрын

    So a 6pk and a couple whiskeys per day, with a pack of smokes is good.

  • @Carbivore67
    @Carbivore6724 күн бұрын

    I have a pint or two a month and that's safe.

  • @robertdimaggio9086
    @robertdimaggio908610 күн бұрын

    A LOT of people are missing the point here. "Alcohol is bad, its good everyone quits" Maybe, unless you're a small to moderate drinker and DONT have the APOe4 gene, then quiting can put you at a higher risk. Stop being generalized, people are unique. This is exactly like the caffeine debate.

  • @TreforTreforgan
    @TreforTreforgan25 күн бұрын

    Well I drink to forget, so…

  • @yaasikasa17
    @yaasikasa1725 күн бұрын

    If the govt legalised it, then stay tf away!

  • @burnhamsghost8044

    @burnhamsghost8044

    23 күн бұрын

    The government legalized water.

  • @deborahwhit118
    @deborahwhit11823 күн бұрын

    Says one alcoholic to another 🙄

  • @carolinapaez5730
    @carolinapaez573025 күн бұрын

    Breast cancer? Any amount of alcohol increses the risk of breast cancer in women. Which risk do you prefer?

  • @Fuzzyblossom

    @Fuzzyblossom

    23 күн бұрын

    So does contraception+ her😵‍💫

  • @Fuzzyblossom

    @Fuzzyblossom

    23 күн бұрын

    Hrt

  • @zubayrbhyat8077
    @zubayrbhyat807724 күн бұрын

    If you cannot afford a genetic test then don't drink alcohol. That's my takeaway.

  • @natpaler883
    @natpaler88324 күн бұрын

    Alcohol is toxic substance and the only drug socially wide acceptable. My life improved dramatically since going sober 15 years ago.

  • @paulbrowning1758
    @paulbrowning175816 күн бұрын

    Sorry, the only studies that I’ll accept, especially when pushed by an “influencer,” are peer-reviewed meta-studies. Doesn’t matter how large a single study is. After learning that so much of what Andrew Huberman and other “expert” influencers say is often bias and unfounded, I don’t want to take any chances, especially when it comes to my health. I quit drinking years ago. Didn’t need any to tell me that any amount is bad for the brain/body. That knowledge is centuries old.

  • @bmelvin1234
    @bmelvin123423 күн бұрын

    She ‘s starting to kill my buzz 😂 just kidding. Seriously I stopped drinking three years ago and feel great. Done with poisoning myself.

  • @DjangoPorter
    @DjangoPorter24 күн бұрын

    Hunans have been. Drinking and enjoying and living on alcohol. Since the dawn of man and its fine

  • @gabymalembe
    @gabymalembe23 күн бұрын

    Hard to give up a guaranteed pleasure for a hypothetical problem.

  • @EvanLoper-pj5wk
    @EvanLoper-pj5wk21 күн бұрын

    Nah you're good keep drinking...

  • @betzib8021
    @betzib802123 күн бұрын

    Nah...it's not good...but sometimes...bliss beats the h out of anxiety short term

  • @Malery

    @Malery

    20 күн бұрын

    Alcohol made my anxiety much worse over time.

  • @betzib8021

    @betzib8021

    20 күн бұрын

    @@Malery yes...I agree...it's not a solution long term...it is insidious that way. I no longer use it.

  • @Therealcarolinaguy
    @Therealcarolinaguy25 күн бұрын

    We get it, but is life without alcohol really worth living?

  • @blackout2430

    @blackout2430

    25 күн бұрын

    I hate alcohol but I feel your pain with my weed addiction. Want to quit but struggle

  • @xxxaldo5xxx

    @xxxaldo5xxx

    25 күн бұрын

    Yeah, how did prohibition work out for the country? Let's see, the new normal is fat, diabetic and full of plastics and pfas. Anyone more concerned about that? How about how junk food is being pressed on society?

  • @rxcashdaddy87

    @rxcashdaddy87

    25 күн бұрын

    what does alcohol have to offer that could make life not worth living without it?

  • @weirdo1083

    @weirdo1083

    25 күн бұрын

    Alcohol is just a fake happiness what you feel when intoxicated you will feel the opposite the next day.

  • @maxstrongCW

    @maxstrongCW

    25 күн бұрын

    If alcohol is the missing piece in your life then it's not much of a life. An unexamined life is not worth living, Buddha

  • @Booogieman
    @Booogieman25 күн бұрын

    We need more safe drugs

  • @AndreyRubtsovRU
    @AndreyRubtsovRU25 күн бұрын

    Dont clickbait us, we sure know its bad

  • @frankasturino3416
    @frankasturino341625 күн бұрын

    You continue to try to tell people that it is safe to drink alcohol. The truth is that there is no safe amount of alcohol and yet you continue to run your mouth. How much money are you getting from the alcohol industry??

  • @TheGlowingOnee

    @TheGlowingOnee

    25 күн бұрын

    When did she ever say that it’s safe? Are you autistic?

  • @hyperhippyhippohopper

    @hyperhippyhippohopper

    25 күн бұрын

    If you can't follow what dr Patrick is saying, and you can't process the level of nuance she is bringing to this complex topic, I think this stuff isn't for you buddy. A comment like yours isn't as smart/witty/insightful as you probably think it is. You're only laying bare the depth of your own stupidity while patting yourself on the back lol...

  • @rinohunter6190

    @rinohunter6190

    24 күн бұрын

    Now now alcohol is fermentation which the body knows how to deal with. The dose is the poison, not all amounts bad

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