This video gives you an intriguing insight into the complexity of the mouse brain. It showcases outstanding data obtained by Gubra, a CRO and Biotech Company from Denmark, using Miltenyi Biotec's Neurofilament Antibody (anti-human/mouse, Vio® R667, REAfinity™) to stain neurofilaments. Tissue clearing was performed using the iDISCO+ method and imaging was performed on the UltraMicroscope platform.
There’s no point in imaging cleared tissue if you don’t get clear signals. Miltenyi Biotec’s fluorescent antibodies for 3D-immunofluorescence (3D-IF) are therefore already validated for 3D imaging of large samples, such as entire mouse brain hemispheres or human tumor samples. Directly conjugated to bright and photostable Vio® Dyes, our recombinantly engineered REAfinity™ Antibodies offer you all the advantages of direct immunofluorescence microscopy: reduced staining time, great signal-to-background ratio, and minimal background signals.
Miltenyi Biotec is a global provider of products and services that empower biomedical discovery and advance cellular therapy. Our innovative tools support research at every level, from basic research to translational research to clinical application. This integrated portfolio enables scientists and clinicians to obtain, analyze, and utilize the cell. Our technologies offer solutions for cellular research, cell therapy, and cell manufacturing. Our more than 30 years of expertise spans research areas including immunology, stem cell biology, neuroscience, cancer, hematology, and graft engineering. In our commitment to the scientific community, we also offer comprehensive scientific support, consultation, and expert training. Today, Miltenyi Biotec has more than 4,700 employees in 23 countries - all dedicated to helping researchers and clinicians around the world make a greater impact on science and health.