Celiac disease is a chronic autoimmune disorder triggered by the ingestion of gluten, a protein found in wheat, barley, and rye. When individuals with celiac disease consume gluten, their immune system mistakenly attacks the small intestine, causing damage to its lining and leading to various symptoms and complications. These symptoms include abdominal pain, bloating, diarrhea, fatigue, and weight loss. Long-term effects may include malnutrition, osteoporosis, infertility, and an increased risk of certain cancers. Diagnosis involves blood tests and biopsy of the small intestine. Treatment primarily involves adhering to a strict gluten-free diet, avoiding all foods containing gluten. With proper management, symptoms can be alleviated, and intestinal damage can heal, allowing individuals with celiac disease to lead healthy lives.