This video covers local treatment options for isolated liver metastatic disease in colorectal cancer. We briefly discuss which types of patients might be candidates for these therapies (reviewing Fong's criteria), and when they might be applied relative to neo/adjuvant chemotherapy regimens. We then discuss formal and wedge surgical resections, as well as liver hypertrophy techniques (PVE, Y-90, LVD) to grow the FLR to promote more extensive resections. We discuss the biologic rationale for hepatic artery infusion pumps for surgical candidates with unresectable disease, and who might qualify for a liver transplant. Finally, we describe ablation and SBRT as non-operative local therapies.
These videos are for educational purposes only and should not be used to diagnose or treat any diseases. This is not clinical advice.