This is How Insulin Resistance Starts (and how to stop it early)

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How Insulin Resistance Develops + Lowering Blood Sugar w/Simon Hill
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Timestamps ⏱
0:00 - Intro
0:19 - 20% off Bubs Naturals
1:35 - How Insulin Resistance Develops
12:00 - How a Fatty Liver Contributes to Insulin Resistance
16:38 - Lowering Blood Sugar
20:45 - The Best Diet For You
24:58 - Early vs Late-Stage Insulin Resistance
27:11 - Low Carb vs Low Fat Diets
30:20 - What Would Simon Do If Diagnosed With Type-2 Diabetes?
31:58 - Is Losing Weight Fast Safe?
33:41 - Should You Exercise When Losing Weight Fast?
35:50 - Do This If Insulin Resistant
37:00 - Weight Loss Is More Than Just Selecting The Right Diet
37:46 - Simon & Thomas' Tips for Maintaining a Healthy Weight
43:33 - Where to Find More of Simon's Content

Пікірлер: 176

  • @abc_cba
    @abc_cba5 ай бұрын

    I love how Thomas allows people of all philosophies to speak up, whether vegan or carnivore, high fat or high carb, etc.. shows how unbiased he is!

  • @xnoreq

    @xnoreq

    5 ай бұрын

    Whatever produces clicks. See clickbait thumbnails and titles.

  • @jamiepatton9334

    @jamiepatton9334

    5 ай бұрын

    I'm don't think anyone is unbiased. But I appreciate the different points of view.

  • @pangeaproxima3681

    @pangeaproxima3681

    5 ай бұрын

    _What?_ _What?_

  • @belojay2850

    @belojay2850

    5 ай бұрын

    Even chaps like this guy with excessive saliva production or something? With his audible swallowing after each and every thought/sentence completion. Geez😳

  • @pangeaproxima3681

    @pangeaproxima3681

    5 ай бұрын

    @@belojay2850 Never undersestimate the amount of fawners and sycophants out there, especially on YT.

  • @leodegas7731
    @leodegas77315 ай бұрын

    Basically, this whole conversation said,"Eat whole foods, whether it's protein or carbs. "

  • @dontfit6380

    @dontfit6380

    5 ай бұрын

    Yup that’s what I did for 40 years and I ended up pre diabetic.

  • @codyeng9148

    @codyeng9148

    5 ай бұрын

    ​@@dontfit6380yeah... That's not why

  • @nicolasbonnet3495

    @nicolasbonnet3495

    5 ай бұрын

    Sure ! Difficult to find the right amount of protein in a vegetarian diet… Hence the emphasis on carbs.

  • @dontfit6380

    @dontfit6380

    5 ай бұрын

    @@codyeng9148 I’m 56 years old and lived on a farm my whole life. Probably 99% of my food comes from the farm. All depending on garden success due to weather. All my meat absolutely comes from the farm. All apples, pears and cherries from our orchard. Wine made from our grapes and elderberries. It took me 40 years but I ended up 60lbs overweight and pre diabetic. I found Thomas and keto here on KZread. After eliminating the high carb vegetables, grain, alcohol and fruit I dropped that 60 pounds in less than a year. Now I have less garden work and the fruit goes to the pigs and chickens. So not only did keto/ carnivore get my health back in order but it’s lightened my work load. Now if heavy carbs, fructose and alcohol didn’t contribute to me getting fat could you please explain why?

  • @dontfit6380

    @dontfit6380

    5 ай бұрын

    @@nicolasbonnet3495 one of the many reasons why the vegetarian diet should be avoided.

  • @karend.9218
    @karend.92185 ай бұрын

    Weird, this doesn’t track with what happened to my husband and I. He was biking 30 km 3-4 x per week summers. He was also pounding gels and was 26 lbs overweight. He had NAFLD. Doc said lose weight. We focused on the grain part of the pyramid, no sugar (baked goods) but ate lots of bread pasta grains, low fat, whole foods, moderate protein, but he still did gels on rides and we did like a chocolate bar or crunchy snack evenings. It was a disaster and made it worse for both of us. Found out about keto and switched gears June 2018. Insulin resistance reversed, weight lost, NAFLD reversed, triglycerides corrected, HDL increased, yes LDL also increased. When we were getting sick, We did not consume much saturated fat or any fat at all, skinless boneless chicken, no butter on veg, no bacon, we ate a lot of grains category. This saturated fat hypothesis does not fit for how we got worse health.

  • @Chris90.

    @Chris90.

    5 ай бұрын

    you could've always done a healthier version of a higher-fat diet that's still keto, but more sources of unsaturated fat with a Mediterranean-based ketogenic diet; nuts, seeds, avocado's, fatty fish, tofu. less saturated fats, red meat, eggs, butter, cheese. would help lipid profiles in conjunction with IR and weight-loss

  • @Chris90.

    @Chris90.

    5 ай бұрын

    @@Beatrice-nx5ld "tend to get diabetes"? do you have evidence for that? because carbohydrates in of themselves don't cause diabetes. (type 2, I should say)

  • @aufsesserpremium

    @aufsesserpremium

    Ай бұрын

    "Dietary guidelines from the World Health Organization and Dietary Reference Intakes recommend total fat intake between 20 and 35% of total calories. The minimum of 20% is intended to ensure adequate intake of total energy, essential fatty acids and fat-soluble vitamins and to prevent atherogenic dyslipidemia (low high-density lipoprotein cholesterol (HDL-C), high triglyceride-rich lipoproteins) which occurs with low-fat, high-carbohydrate diets and the risk of coronary artery disease Heart disease increased." That translates to ~ 50% carbs, carbs are NOT thought to come from high glycemic index processed grain products as normal bread & Co...but vegetables, legumes and partly whole grains with lot`s of fiber and micronutriants. Never eat "naked" carbs, always with protein to prevent glucose spikes,...small portions ~ not more than ~ 50 gramms... Above a BMI of 20 -21 the risk of Diabetes is already rising....(visceral fat), a BMI 25 = 5 x greater risk than 22.5...(nurses health ~ something study...) Chicken fat = just ~~ 30% saturated fat, but lot of unsaturated oleic acid 42% (as in olive oil...) and PUFA linoleic acid 17% and only 23% palmitic acid....pork fat also has ~ 45 + % oleic acid....Wiki even claims...."Pork fat contains oleic acid with 60% monounsaturated fat.... with just some extra olive oil you easily get a perfect 20/80 saturated/unsaturated ratio .... From the saturated fat point of view...milk fat is worse..."Almost 70% of the fat in milk is saturated of which around 11% comprises short-chain fatty acids, almost half of which is butyric acid. Approximately 25% of the fatty acids in milk are mono-unsaturated and 2.3% are poly-unsaturated." What makes not too much sense, cause studies point to reduced risk...but it`s complicated... milk contains 400 different fatty acids.....and butyric acid is very healthy for the gut....

  • @myronm5338
    @myronm53385 ай бұрын

    I was diagnosed with T2D in March last year. Went on a 1000kcal deficit diet which included eating as much whole foods and intermittent fasting. Dropped 15% body weight within 8 weeks. Hb1ac dropped to 6%. Since then took on resistance training and my hb1ac dropped to 5,5%. Body fat is around 11%. The other key elements is reducing stress and having good sleep to maintain a long term health strategy.

  • @annebayliss9886

    @annebayliss9886

    5 ай бұрын

    Brilliant, you took responsibility for your health and did something about it, I really wish everybody could accept that it’s mostly up to us to stay healthy over our life time

  • @xnoreq

    @xnoreq

    5 ай бұрын

    What was your BMI when you were diagnosed?

  • @myronm5338

    @myronm5338

    5 ай бұрын

    25.7 BMI . I have a low personal fat threshold!@@xnoreq

  • @aounjose
    @aounjose5 ай бұрын

    What is frustrating to me about most of these experts is that they center the problem around the need to loose weight. In my case this does not apply. I eat very low carbs, train 15 hours a week am very lean and still have insulin resistance. I just cant figure this out. The endocrinologist that Ive gone to here in the US have said that there is not much to do because my A1C is Ok. The analogy I give them is that if you have a car tire, and you measure the pressure and it is within range that could mean that the tire is ok, however if I tell you that I inflate the tire 5 times a day, then there is definitely a hole in the tire even though that when measured the pressure was within range. Sorry about the rant, I would love some guidance.

  • @charpacitto1496

    @charpacitto1496

    5 ай бұрын

    That’s interesting, I’d like to hear some feedback to this

  • @asinh1100

    @asinh1100

    5 ай бұрын

    Give charity to poor and animals .. esp food .. blessings help

  • @jasonghobbs

    @jasonghobbs

    5 ай бұрын

    Do you still eat foods high in Linoleic acid (Seed oils, many ultra processed foods, many nuts)? I'm no expert. I will be interested to see what people say on the matter.

  • @johnreyes4365

    @johnreyes4365

    5 ай бұрын

    What you have to do a lab fasting insulin level it could be very high ,skinny doesn't mean healthy, you could be fan in the inside fatty liver focus in your insulin level

  • @ZmogusJaponija

    @ZmogusJaponija

    5 ай бұрын

    Almost my case. What is exactly your diet. Low carb, yes thats clear, but what else? Protein sources? Fat sources? Processed food?

  • @XOXO123456789
    @XOXO1234567895 ай бұрын

    Thomas, seriously, thank you for all the amazing content you put out. It’s highly appreciated 🙏🏼

  • @YasminA-jm9zs
    @YasminA-jm9zs5 ай бұрын

    Thank you Thomas for bringing in so many amazing people and giving them a platform to speak!

  • @skincraftorganicsllc8537
    @skincraftorganicsllc85375 ай бұрын

    As ALWAYS, excellent content, thank you!!

  • @garykesinger1725
    @garykesinger17255 ай бұрын

    A lot of good, evidence backed advice for both the low and the high carb crowd. Simon knows his subject and his podcast brings on some of the top nutrition researchers in the world. Well worth a listen.

  • @xnoreq

    @xnoreq

    5 ай бұрын

    Balanced and low fat are superior for health and longevity. High fat should only be used in rare medical cases.

  • @garykesinger1725

    @garykesinger1725

    5 ай бұрын

    Agreed.

  • @jamesalles139
    @jamesalles1395 ай бұрын

    thanks for the discussion I appreciate your touching on satiation. I believe there is more of an issue with blood Glucose spikes, in that it lays down/dissolves the glycocalyx which requires time to recover. This allows for more damage from inflammatory products.

  • @shelleyhodgkinson1341
    @shelleyhodgkinson13415 ай бұрын

    Always super interesting!

  • @MichelleLathrom
    @MichelleLathrom5 ай бұрын

    That is not true. A fatty pancreas doesn’t cause a reduction of insulin. Insulin production actually is insanely high. Also a type 2 diabetic doesn’t have lowered insulin production. It’s actually insanely high. Just cause sugar is high doesn’t mean insulin is low. You can’t tell where insulin is based on sugar levels. You have to check insulin levels to see where insulin levels are.

  • @HansMulliah

    @HansMulliah

    5 ай бұрын

    It does actually

  • @HansMulliah

    @HansMulliah

    5 ай бұрын

    It does actually

  • @MichelleLathrom

    @MichelleLathrom

    5 ай бұрын

    @@HansMulliahit actually doesn’t. I have both of these conditions and my insulin is not low but insanely high. And so is the insulin for many of my clients. Their insulin is high. Not low. Sugar levels don’t dictate insulin levels. And the amount of fatty deposits in either liver or pancreas do not correlate with insulin production. If anything it points to high insulin levels. You need insulin to deposit fat. An undiagnosed and untreated type 1 diabetic will not have a fatty liver nor will they have hardly any fat on their body. And often they have severe muscle loss too. Because insulin is a requirement for fat and muscle growth. Extra fat means you’ve had extra insulin flowing thru the body. Not less. If people would just get their fasting insulin levels checked, it would be clear. But doctors never order that. Even worse, they fight you when you as a patient ask for it. They say it’s not necessary or important. But it is the exact cornerstone of the whole problem of insulin resistance and metabolic issues.

  • @xnoreq

    @xnoreq

    5 ай бұрын

    Insulin production is only high at the beginning of diabetes. The fat, inflammation and cell damage will reduce insulin production over time.

  • @RobCGilliam

    @RobCGilliam

    5 ай бұрын

    right on. It's not a static process. Pancreas is in overdrive in the beginning stages and declines. I don't know it it is the fat build up that eventually reduces the function of the pancreas, but it goes along with it. Fat accumulation certainly has a negative impact on the liver function.@@xnoreq

  • @wendygreenfield9631
    @wendygreenfield96315 ай бұрын

    This was a really helpful conversation. I have an elderly family member struggling with diabetes. You provided some great info... Thanks!!!

  • @xnoreq

    @xnoreq

    5 ай бұрын

    What is their BMI?

  • @brandonbernitz2431
    @brandonbernitz24315 ай бұрын

    Super informative episode Thomas! Interesting and definitely worth listening. You are truly and definitely one of the few unbiased experts out there.

  • @dagb9616
    @dagb96165 ай бұрын

    Thank you for this discussion. Great guest. I’m encouraged by the idea that there are many different diets that can be effective. But one question about fats. I’ve read that there is a night and day difference between natural saturated fats like in butter, beef fat, and lard as opposed to factory made hydrogenated fats. Do you see that in the research? It seems like an important distinction to me. I’ve been following a low-carb diet for a few years, and more recently, fasting/intermittent fasting. I’ve lost over 100 pounds and brought my A1c from 13.9 to 5.4. I’m still on 500mg of Metformin, but should discontinue that soon. I’m 66 and feel better than when I was 36. Statin drugs about killed me, and made it impossible to do weight training, a few years ago. But I've been slowly regaining my strength now that I stopped taking those. To any old dudes out there, never quit, never give up.

  • @peggykey5570
    @peggykey55704 ай бұрын

    Thomas doesn't care what anyone says , you are always informative and love hearing what you say

  • @davesworld7961
    @davesworld79615 ай бұрын

    For those needing to avoid saturated fat is Mct oil included in the saturated fat to avoid or is that an exception.

  • @user-zd5ny5tl1n
    @user-zd5ny5tl1n5 ай бұрын

    Could you do video on coolsculpting/fat freeze if helpful as a tool apart from good diet and exercise to get rid of last few kilos of difficult pockets of fat such as stomach, arms etc for women. If it is good or detrimental to health. Thank you

  • @peggykey5570
    @peggykey55704 ай бұрын

    Ignore others. Love this

  • @baileystruss7319
    @baileystruss73195 ай бұрын

    How can we really determine amount of visceral fat beyond the waist circumference ratio,? CT scans?

  • @stephaneetchayde

    @stephaneetchayde

    5 ай бұрын

    The waist circumference is not fully reliable as, as Dr. Robert Lustig explains in his various interviews available on KZread, about 20% of obese people are metabolically healthy, meaning they carry on a lot of body fat but only in the subcutaneous adipose tissue where it is supposed to be stored, and not within the abdominal cavity (visceral fat) nor in other places (ectopic adiposity : fatty liver, pancreatic steatosis, myosteatosis, etc.). Pr. Roy Taylor has developed the concept of personal fat threshold : you start accumulating body fat outside the subcutaneous adipose tissue in visceral and ectopic depots once you've reached that threshold, which varies from people to people and explains why you have metabolically healthy obese people and skinny fat (thin on the outside and fat on the inside) people. So the morphology and hence the waist circumference are not always good indicators of metabolic health. Dr. Sean O'Mara specializes in eliminating pro-inflammatory visceral adipose tissue, so I'd advise you to consult his KZread channel and his website and listen to the numerous interviews he gave on the topic that are available on KZread. Visceral fat levels can be determined via a DEXA scan and via an abdominal MRI. Dr. Sean O'Mara advocates for the MRI over the DEXA scan because it allows you to see the visceral fat present in your abdominal cavity, which can be a better eye-opener to understand the downstream damages it can cause and start addressing the issue, but an MRI is much more expensive than a DEXA scan.

  • @markd4768
    @markd47685 ай бұрын

    It’s a really good question! 😂😂

  • @AliceFarmer-bg4dw
    @AliceFarmer-bg4dw5 ай бұрын

    Why were the ancient Egyptians riddled with Heat disease and a diet with wheat bread and grains

  • @HarrisonCountyStudio

    @HarrisonCountyStudio

    5 ай бұрын

    I think the answer is in your question. It was in their diet.

  • @NostalgiNorden

    @NostalgiNorden

    5 ай бұрын

    They where also inbred like crazy.

  • @trentonharris7676
    @trentonharris76765 ай бұрын

    "Insulin resistance" is not a pathology in need of remedy. It is part of the natural physiologic response to the inappropriate consumption of carbohydrates.

  • @brandonodonnell7675
    @brandonodonnell76755 ай бұрын

    What about type 1 Thomas

  • @followerofchrist198
    @followerofchrist1985 ай бұрын

    How do you know it’s the Saturated Fats rather than what people who often eat high saturated fat diets often eat it with eg seed oils, bread, pastry etc?

  • @birchtreeweb
    @birchtreeweb5 ай бұрын

    Can you define what is considered a “low carb diet”? I’m currently eating “modified keto”; 10% carbs (48 grams), 25% protein (121 grams), and 65% healthy fat (139 grams). I’ve been seeing my blood trending in the right direction but have hit a bit of a plateau on weight reduction which is highlighting the importance of exercise. I don’t have Type II diabetes but should signs of NAFLD and what a good macronutrient mix would be to reverse this?

  • @RobCGilliam

    @RobCGilliam

    5 ай бұрын

    I went through keto phase. Think it can be used as a short-term tool. But as one continues their LDL increases. Mine was in the 80s since regular testing 20 years ago. Keto pushed it to 130 after 6 months and close to 180 after 18. This is the big issue with keto for many. It raises long-term risk of heart disease. After being referenced to a cardiologist, I went low fat whole food plant-based. I'd consider this as it will melt fat away and is the best for the circulatory system. Throw in a 16/8 fast/feeding intermittent fasting and you will burn fat off the liver quick. My numbers improved (AST went from 47 to 30) after 3 months including my LDL that dropped from 175 to 60.

  • @birchtreeweb

    @birchtreeweb

    5 ай бұрын

    @@RobCGilliam thanks. My LDL is 58, triglycerides and HDL are great. I’ve been doing an 18/6 intermittent fasting and my liver numbers are slowly trending down. When I added intermittent fasting I saw my numbers tumble. Still hoping to lose more belly fat. Resistance training helps and the winter has put a damper on my kayaking. I’m utterly amazed at how pizza or bagels throw a wrench in things. When I avoid those my weight continues to trend downward. Guess I need to remain patient, have only been following modified keto since early Fall.

  • @RobCGilliam

    @RobCGilliam

    5 ай бұрын

    Those are super numbers. I'd keep on that track. Shows we are all different. Think I fit in a hyperresponder cohort where LDL increases on keto. But one could transition to a more balanced diet and likely get similar results if the daily caloric intake is the same. But if your lipids remain like they are now and everything else looks great... keep it up. I did have a lot of cramping problems surfing on keto. It was an ongoing thing to manage electrolytes. No issues on a lower fat, whole-food carb diet. @@birchtreeweb

  • @derekclary6019
    @derekclary60194 ай бұрын

    What are your thoughts on the Mastering Diabetes method of eating high carb, low fat and claiming to reverse Type 2 diabetes and insulin resistance?

  • @kaitlananderson4302
    @kaitlananderson43025 ай бұрын

    So having a more balanced diet with moderate healthy carbs and moderate saturated fat from high quality sources is no good? You have to go to one extreme or the other?

  • @YanniGoudelis
    @YanniGoudelis5 ай бұрын

    If I could just have one favorite, Keith would be it!

  • @You2be4life
    @You2be4life5 ай бұрын

    I cut out carbs to only eating 10 grams per day and started having heart palpitations and became dizzy when doing moderate hikes. I HAVE to eat carbs but I make sure to eat the healthy carbs.

  • @gcs7817
    @gcs78175 ай бұрын

    Either you go clean whole food high carb , very low saturated fat Or low carb , low saturated fat Either way, saturated fat is the item to reduce despite the fact that no study has produced a result that saturated fat causes cardio vascular events or T2D Humans have been eating saturated fats and animal proteins for millennia and T2D wasn’t a thing like it is in past 30 years

  • @justinmininger5973
    @justinmininger59735 ай бұрын

    This guy isn't telling you anything you haven't already told us, and he doesn't seem to have any solid evidence or self assurance of his own words. Really appreciate what you do by the way.

  • @RobCGilliam
    @RobCGilliam5 ай бұрын

    Thomas is doing some great work although I've shifted from the low-carb ketosphere because it harmed my numbers. I found super low saturated and lowish fat overall the best for the insulin resistance I had a few years ago. Keto actually made AST level ping fatty liver. I'm all good now with great numbers including fasting insulin down at 2, much better liver enzymes and ideal BMI sitting near 10% body fat.. However, my younger brother is massively overweight and has fatty liver. He's on the autism spectrum so trying to advise him on healthy eating. I think super low fat overall would be best, but requires so much food prep because whole food good carbs require so many veggies. High fat, low carb may be easier for him, but his cholesterol is high and this may help reduce weight short-term and help reduce liver fat, but long-term is likely not good.

  • @ZmogusJaponija
    @ZmogusJaponija5 ай бұрын

    I was low carb+ fasting for many years. Initially it helped to fight off the sugar/flour addiction and to loose some weight. But as the time past, it was more and more difficult to maintain - I felt always hungry, fought it with coffee and got addicted to it. I started to have episodes of over-eating. Gained some fat weight and the worst of it LDL went to 140 (well what to expect after eating too much cheese, and 4 eggs per day). Started to look for the way out. Listened to Simon's podcasts, Rich Roll, D. Sinclair, bought Gregrer's How not to die. Decided to try whole foods plant based approach. I was not eating much meat anyways, so just ditched eggs and diary. Still eating moderate carbs (beans, lentils, oats, buckwheat), so no bread, pasta, etc. Also still eating in 20-4 principle (eating between 9 am - 1 pm). What surpriced me, that I am not hungry, although am in calorie deficit. Also I am not tired/sleepy after meals, which was always the case recently. Losing some fat as well. Let's see where it will bring me.

  • @gcs7817

    @gcs7817

    5 ай бұрын

    People who eat mostly fat and animal protein aren’t hungry between meals

  • @JustBrowsing777

    @JustBrowsing777

    5 ай бұрын

    Dietary cholesterol incl eggs have nothing to do with serum cholesterol. Old myth proven wrong and even the American Heart Association has recognized this not too long ago.

  • @ZmogusJaponija

    @ZmogusJaponija

    5 ай бұрын

    @@gcs7817 good for them, but I am not those people. Also I've read many comments where people shared the same outcome as mine after several years of low carb.

  • @-Trish-

    @-Trish-

    5 ай бұрын

    @@ZmogusJaponija I had problems on low carb as well, but I would never go plant-based again. Maybe for a month or two. I had issues eating a whole food plant-based diet. As do many many people. Maybe you should add a little bit of animal products couple times a week.

  • @DaveThomson

    @DaveThomson

    5 ай бұрын

    worst of it your LDL went to 140? Really? Thats the worst of it? Too muche emphasis on LDL.

  • @soulcostume
    @soulcostume5 ай бұрын

    This is my favorite being from a plant based community. 😍😍 When it comes to this topic, let's call Dr. Bikman.

  • @azdhan
    @azdhan5 ай бұрын

    Simon is the best!!! I recall so many times posting on your videos referencing Professor Roy Taylor’s work to push back and refute some of your questional claims about the cause of T2D Thomas, but it appeared to fall on deaf ears I am glad you invited Simon to further speak to it, as it may make more sense to you now, no offense!

  • @esotericsolitaire
    @esotericsolitaire5 ай бұрын

    We should count our blessings in that we live in a day and age with so much food at our fingertips that we have to navigate a dense maze of how to eat. People used to have few choices and spent much of their time looking for food. I know thin people here in the US that have been diagnosed with NAFLD. That shows you the power of pop tarts, pizza, crackers, fruit juices, candy and American breads and cereals, to name just a few. I see active, thin people eating these three meals per day, every day.

  • @gcs7817
    @gcs78175 ай бұрын

    The calories in, calories out model does not account for the body hormone response to macro nutrients. The calories in, calories out model is outdated

  • @esotericsolitaire
    @esotericsolitaire5 ай бұрын

    43:25 Lol! Amen.

  • @SHGmail-rj2tj
    @SHGmail-rj2tj5 ай бұрын

    Just doing the 18 hours fasting, 6 hours feeeding window (even when continuing to eat high carb foods…ALL food! ) has seen me loose weight from 97kg down to 91kg over 6-8 weeks…… 100% No other changes whatsoever in diet OR exercise!…….. When you feel hungry (and you definitely will😬) comprehending that that nagging feeling is a very positive thing and it will pass, it’s pretty easy to push through……. Well worth what would have to be a fairly minimal effort all things considered, instead of just buckling and falling back into the old habit of eating some brilliant tasting CRAP while watching KZread videos and slowly piling on the pounds. 🙈🤯………I’m just hoping that it’s been all fat shrinkage and no muscle!!. Am doing 2 scoops WPI to break the 18 hour fast…….If I drop down past 88-89kg what I weighed consistently throughout my 20-30s (last ten years added on at times 10kg) I’ll know I’m loosing muscle I guess? Which I obviously don’t want to do…….

  • @troyheald77
    @troyheald775 ай бұрын

    AAA+++Bedford, Texas

  • @susanbeever5708
    @susanbeever57085 ай бұрын

    Insulin resistance comes when the cell resists the insulin receptor. This happens after TRPV1 has force fed glucose into cells as insulin stimulates TRPV1 and TRPV1 does not use the insulin receptor to put glucose into the cell. Additionally, too much TRPV1 stimulation on the mitochondrial membrane causes reactive oxygen species production in excess of the cell’s antioxidant reserves including lipid oxidation (oxLDL). Too much calcium influx into mitochondria damages the mitochondria and leads to apoptosis of the cell. Glp-1RA stimulate the g-protein coupled receptor that lowers the threshold for stimulation of TRPV1. Supplements such as dietary capsaicin in capsules and drugs such as the antiseizure drug oxcarbazepine up-regulate TRPV1. A study of PCOS women with metabolic syndrome were treated with capsazepine a TRPV1 antagonist and selenium an antioxidant and their lipid oxidation resolved.

  • @danicajefferson1428
    @danicajefferson14285 ай бұрын

    Thomas can you address how to lose weight for women above 50 years old and how calories below 1000 a day makes you keep weight on.

  • @anitahernandez1207
    @anitahernandez12075 ай бұрын

    My father was not obese when alive, but was diabetic and died from kidney failure during a hip transplant. Years before that, he had 2/3 of his liver removed but it eventually grew back. Sometimes, he would gain some extra weight but could loose 15lb in a month by going carnivore. Since most of civilization in the past, farmed, hunted and ate seasonally up until after WW1, a person should be able to carry a little extra weight during the year and not suffer from that natural process. Many people are gaining holiday weight but it's from junk food. People want to loose the weight in the spring and summer when foods are nutrient dense. I believe that conventional meat (non organic /not grass fed, grass finished), conventional produce (non organic) and ultra processed foods, including oils, flavorings (MSG), additives and other modified natural foods, are chemically and genetically toxic, (pasteurized milk, genetically modified cattle, GMO wheat and sugar, etc.) creating many different mitochondrial issues within the body, whether a person has muscles or not. 🧬🧠Carbs have an effect on people mentally as well as sugar, so "earning" it with activity is a good idea. Exercise has an effect on the mind as well.

  • @MrDjhealth
    @MrDjhealth5 ай бұрын

    Dr Michael Eades MD once said your liver uses saturated fat in order to cause a fat dump in the liver

  • @Taliatekito
    @Taliatekito5 ай бұрын

    I get the impression Thomas is being very polite and disagreeing with this ‘twin cycle’ hypothesis

  • @fizywig
    @fizywig5 ай бұрын

    Cards are addictive so best avoided or kept to a minimum

  • @xnoreq

    @xnoreq

    5 ай бұрын

    BS. Fat oxidation is much more damaging.

  • @xnoreq

    @xnoreq

    5 ай бұрын

    Nonsense. Carbs are the preferred fuel source and fuel all our body's cells, and enable the most efficient and healthy metabolism. Fatty acid oxidation is less efficient and more damaging due to the extra oxidative damage, the ROS causing DNA damage etc.

  • @BeckyJB
    @BeckyJB5 ай бұрын

    Interesting…..😂 I sustained gaining 3-5 lbs a month last year eating organic whole foods and exercising 3-5 days a week. (When my goal was to loose 30lbs) My strategy was changed to Keto and getting more results without exercise. Lost 10lbs in the first month. 😂😊 good to see Thomas discussing the topics in podcast style ❤ great job 👏

  • @DckTrcy
    @DckTrcy5 ай бұрын

    These people are obviously not carb addicted

  • @DJSTOEK
    @DJSTOEK5 ай бұрын

    ❤❤

  • @alan30189
    @alan301895 ай бұрын

    After the about the tenth gum-smacking, I couldn’t listen any longer. WTF? That drives me nuts. He needs to address that.

  • @dmercier6437

    @dmercier6437

    5 ай бұрын

    I thought it was just me

  • @richardmiddleton7770
    @richardmiddleton77705 ай бұрын

    I thought that as you get more fat adapted, you naturally store more fat in the muscles for immediate use?

  • @allybally0021
    @allybally00213 ай бұрын

    Not the best information. It cites studies that support higher carbs but with little on cause-effect of carbs on metabolism. There are always multiple studies that point to every point of view on an issue. However for most people low carb is proven through logic and studies. Thomas of course allows differing point of view and that's fine - its a good channel.

  • @faimohkihfaimohkih8223
    @faimohkihfaimohkih82235 ай бұрын

    Wow! A 45 min discussion on insulin resistance and not a single mention of hyperinsulinemia…the guest went from insulin resistance at the level of the liver to basically adult onset type I diabetes from pancreas burn out…what?? How bout the fact that almost all obese patients who don’t have type II diabetes have elevated fasting insulin levels (I have yet to see an obese patient that does not) and that most of the negative consequences of insulin resistance stem directly from elevated insulin (hypertension, heart disease, increased cancer risk, etc). Also, I think we need to take any weight loss study or insulin resistance study that is not looking at body composition, with a grain of salt. All the studies for GLP-1 agonists showed successful weight loss but now that many of those patients are being followed up with Dexa scans, it is clear that most of the weight lost was lean mass. Isn’t it interesting that GLP-1 drugs also raise insulin 🤔?? You may be able to lose weight on any kind of diet that creates a caloric deficit, but if you don’t lower insulin in some way or another, you will have a much harder time losing fat mass. This should be the main goal of anyone with insulin resistance!

  • @phillipsmith3545
    @phillipsmith35455 ай бұрын

    Love your content, but this one seemed off, like both were not super prepared for the video. Both are great, but when y’all came together, didn’t click. I felt like you guys were trying to walk on egg shells to not hamper on vegan or not vegan. Keep chugging though!

  • @esotericsolitaire
    @esotericsolitaire5 ай бұрын

    Sorry, but in the school of life (7 decades), I've seen people lose a pile of weight rapidly and keep it off (very rare). Most people do gain all that weight back and then some. And the ones who keep it off after losing rapidly look to have aged ten years. I'm not sure why. My diabetic friend, who was once as wide as she is tall, lost the weight over five years and she looks a good twenty years younger. I maintain that something about rapid weight loss ages you.

  • @AliceFarmer-bg4dw
    @AliceFarmer-bg4dw5 ай бұрын

    Do carnivorous people get diabetes and/or heart disease? Do vegans get diabetes and/or heart disease? Do plant based people get diabetes and/or heart disease?

  • @BGr8ful4all

    @BGr8ful4all

    5 ай бұрын

    Yes carnivorous people get diabetes and/ or heart disease. And yes vegans that still eat highly processed food can too. Whole food plant-based vegans, not so much from what I've read. I am not a doctor, but know several that say the same thing

  • @AliceFarmer-bg4dw

    @AliceFarmer-bg4dw

    5 ай бұрын

    @@BGr8ful4all interesting the ancient Egyptians were riddled with heart disease and were plant based diets.

  • @jazza422

    @jazza422

    5 ай бұрын

    @@BGr8ful4all impossible to get diabetes on carnivore, it actually reverses diabetes. (type 2)

  • @BGr8ful4all

    @BGr8ful4all

    5 ай бұрын

    @@AliceFarmer-bg4dw actually you're very wrong. The poor ones ate bread, beer, they also had dairy products and fish in addition to the fruits and vegetables. The rich ones ate a lot of corpses of animals.

  • @dontfit6380

    @dontfit6380

    5 ай бұрын

    @@BGr8ful4all and how would you know if carnivore’s get diabetes and heart disease? You don’t know any carnivore’s. There are no studies on carnivore’s getting diabetes or heart disease so please enlighten me as to how you came to this conclusion.

  • @stellat2405
    @stellat24055 ай бұрын

    why is it so hard for you Thomas to wear nice long sleeves and trousers like Simon who looks much more sexy and cool. Don't complain if ppl are confusing you with V Shred

  • @beardumaw24
    @beardumaw245 ай бұрын

    Sorry I disagree with some of what this guy says. Dr Erick Westman has 20 years clinical work treating people with metabolic disorder using ketogenic diets. His research shows excess carbs and sugars lead to fatty liver and metabolism disorder, not fats. Simon is plant based and has shown his bised opinions in the past demonizing fats and animal based foods, he sees what he wants out of his studies. Would like to see Dr Erick Westman debunk him.

  • @baileystruss7319
    @baileystruss73195 ай бұрын

    And all the self appointed youtube folks pushing for more saturated fats. I've never felt good about that. And I'm doing keto.

  • @chrisc7262
    @chrisc72625 ай бұрын

    No refined carbohydrates, so no bread, flour, pasta, rice, etc. So, nothing surprising about what he is saying.

  • @WalkDisneyWorld
    @WalkDisneyWorld5 ай бұрын

    First

  • @NostalgiNorden

    @NostalgiNorden

    5 ай бұрын

    Dork.

  • @sherlyr.
    @sherlyr.5 ай бұрын

    Iusually appreciate Thomas' contents, but this one was 'whatever'.

  • @ThomasDeLauerOfficial

    @ThomasDeLauerOfficial

    5 ай бұрын

    You win some you lose some

  • @stevecarpenter2638

    @stevecarpenter2638

    5 ай бұрын

    ​@@ThomasDeLauerOfficialseeds probiotics vs sunwarrior probiotics? What one is better?

  • @MeMyselfAndKgore
    @MeMyselfAndKgore5 ай бұрын

    The guy being interviewed is using very careful langue to avoid saying that the biggest factor for most people is to cut carbs. Yes we all know there's good carbs and bad fat, it's not productive to put in that context

  • @Burt_Sampson
    @Burt_Sampson5 ай бұрын

    Anyone else find it irritating how many mouth sounds this dude makes when he talks? 😂

  • @Ele-kn8vq
    @Ele-kn8vq5 ай бұрын

    Tired of hearing this diet and that .. !!! Not one size fits all.

  • @GiovanniRuedaMarketing
    @GiovanniRuedaMarketing5 ай бұрын

    He is a terrible teacher

  • @anechoicmedia
    @anechoicmedia5 ай бұрын

    more vegan content please!

  • @NostalgiNorden

    @NostalgiNorden

    5 ай бұрын

    No thanks.

  • @samorr4
    @samorr45 ай бұрын

    DeLauer is becoming increasingly disappointing.

  • @ThomasDeLauerOfficial

    @ThomasDeLauerOfficial

    5 ай бұрын

    What’s up? Just curious why you say so on this video? Personally thought this was pretty nuanced and an interesting discussion.

  • @arechikitsune

    @arechikitsune

    5 ай бұрын

    @@ThomasDeLauerOfficial most likely just a troll. only trolls say such things without providing context.

  • @gkgunn53

    @gkgunn53

    5 ай бұрын

    13:00 Hmmm. I find his content is usually well presented. Thomas is good at moving the subject forward. Where is your channel? Perhaps your wisdom is meaningful. I have my doubts.

  • @Joy80JJ

    @Joy80JJ

    5 ай бұрын

    He changes with what science shows. I do not think he is disappointing. I enjoy these different views.

  • @StreetTruckinTitan

    @StreetTruckinTitan

    5 ай бұрын

    @@ThomasDeLauerOfficial Obviously just another hit and run troll.

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