The Infamous Drug Trial That Shocked Britain | Real Stories Full-Length Medical Documentary

On Monday 13 March 2006, eight healthy young men took part in a clinical trial of an experimental drug known as TGN1412. The drug was intended to treat leukaemia and had already been successfully tested on monkeys but never on humans.
It should have been a routine clinical trial but it soon spiralled into one of the most infamous medical emergencies in recent British history.
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  • @AugustBreak
    @AugustBreak5 жыл бұрын

    It’s truly strange watching British documentaries as an American. American documentaries are so loud with constant motion and nonstop drama. I appreciate watching something that takes its time to tell the story without the need for embellishment.

  • @therealgamingderps9608

    @therealgamingderps9608

    5 жыл бұрын

    I mean this was quite intense too.

  • @unknownartist6898

    @unknownartist6898

    5 жыл бұрын

    August Break Same

  • @livelaughForte

    @livelaughForte

    5 жыл бұрын

    It isn't that it's British. They just didn't really need to be flashy because of the content... People fighting for their lives... pretty hardcore as is

  • @AugustBreak

    @AugustBreak

    5 жыл бұрын

    L L there’s a balance that a lot of documentaries and reality shows strike. This one hits right on the mark.

  • @elisesatter1473

    @elisesatter1473

    5 жыл бұрын

    August Break omg ikr!

  • @kaylajohns1020
    @kaylajohns10205 жыл бұрын

    I can’t imagine being the person who received the fake medicine, and having to sit there, listening to all this wondering if you are next.

  • @scoobty4449

    @scoobty4449

    5 жыл бұрын

    Wait I don't get this where do they say that they were given the fake drug?

  • @kaylajohns1020

    @kaylajohns1020

    5 жыл бұрын

    two people recieve something completely else while the others recieve the drugs. But no one knows who got what but the doctor/nurse. i believe its explained in the beginning of the video.

  • @hannestorstensson8845

    @hannestorstensson8845

    5 жыл бұрын

    neither the docs nor the nurses knew, only the one who packaged them.

  • @neontv15

    @neontv15

    5 жыл бұрын

    at 8:03

  • @kaylajohns1020

    @kaylajohns1020

    5 жыл бұрын

    ah thats right, thanks.

  • @burns1921
    @burns1921 Жыл бұрын

    I have been receiving a type of monoclonal antibody infusion every 4 weeks for the last 10 years to treat an autoimmune disease. This medication saved my life and allows me to continue surviving. The people who are willing to submit themselves to clinical trials like this are part of the reason I’m still alive, and I have so much respect for them.

  • @loveisreal7766

    @loveisreal7766

    8 ай бұрын

    True but 😅😅😅😅

  • @sondragraf7609

    @sondragraf7609

    8 ай бұрын

    My son has a number of symptoms that are autoimmune in nature rendering him at 35 unable to work and using a cane but some days unable to leave the bed. He has been given possible bur never firm diagnosis for everything from MS to Parkinsons to Meneirs to heavy metal intoxication as he shows signs of all. One of the neurologists who seemed most hopeful finding neuropathy and all the signs of his own immune system attacking his digestive and nervous systoms suggested a drug to him which was described as a chemo drug originally for cancer patients but has shown to aid patients such as he. God i wish we coyld speak to you to somehow find out if you have a similar set of issues. If so much comfort it would be while making this very important and heart wrenching decision

  • @StrangerInMorocco2023

    @StrangerInMorocco2023

    8 ай бұрын

    I also have an autoimmune disease. I am taking Telfast and Montelukast daily. If I stop, my throat gets tight and itches all over the body. I live with misery and doctors couldn't help me.

  • @lady4191

    @lady4191

    8 ай бұрын

    There probably not so happy

  • @yuliaschannel6288

    @yuliaschannel6288

    8 ай бұрын

    Maybe try prolonged water only fast around 10 days? Prolonged fast is the only thing that treats and cure autoimmune diseases. And then carnivore diet.

  • @india1422
    @india14223 ай бұрын

    I'm being treated for ovarian cancer. I cannot express my gratitude to the people who have risked their life to try to save mine

  • @adamdadds4566
    @adamdadds45664 жыл бұрын

    Patient “am I going to die?” Doctor “the real question is am I going to prison?”

  • @obelisk5358

    @obelisk5358

    4 жыл бұрын

    @Kimber 10MM wtf are you talking about

  • @itz_bk

    @itz_bk

    4 жыл бұрын

    @Kimber 10MM don't you understand it's just a joke , if you don't understand, Okey let me tell you it's a human thing & you need to settle up in a zoo

  • @diallogazali7538

    @diallogazali7538

    4 жыл бұрын

    That’s funny

  • @johnimusic12

    @johnimusic12

    4 жыл бұрын

    😆

  • @0906blue

    @0906blue

    4 жыл бұрын

    It's an experimental drug, he volunteered.

  • @mb4692
    @mb46925 жыл бұрын

    I still remember how my 6th year biology teacher warned us to never volunteer to be a guinea pig. Thank you sir.

  • @Olivia-W

    @Olivia-W

    5 жыл бұрын

    See, I'm thankful I study chemistry, not biology or medicine. I can watch them do trials from another building, thanks.

  • @yudelleanlisatajirikenyana4519

    @yudelleanlisatajirikenyana4519

    5 жыл бұрын

    Honey Bee 😂😂😂 that's a great teacher

  • @jasonsage1417

    @jasonsage1417

    5 жыл бұрын

    I had a science teacher start our origins, universe life etc with: don’t believe everything they tell you, remember many think a supreme being, god, caused creation, others do not... in any case we don’t know how or why the universe came into being let alone having physics perfect for star formation, nuclear reactions, time, matter, all of it. That said... shall we begin.... first there was nothing, then there was a universe... any questions? Right... ok.. and we opened our books to chapter one. The Big Bang. Haha and the lesson commenced. I thought he was clever and wise and he was a great teacher. He also gave us real experiments, not cheesy ones. More dangerous chemicals and dissection, less baking soda and vinegar. Haha... break out the scalpels and Bunson burners baby.. whoops. Bang. Teacher my test tube is no more! You ok? Yeah. Had your eye wear on? Yeah. Ok... do it again but this time don’t skip step three in the directions... sorry Mr. Moss. Haha he was cool.

  • @renees1021

    @renees1021

    5 жыл бұрын

    The FDA also recommends not being the first to take new drugs; I'd suspect only people desperate for money (poor/poverty) would/will volunteer.

  • @darianbarber3763

    @darianbarber3763

    5 жыл бұрын

    @@renees1021 I don't think they normally end this badly due to prior testing on animals but yea this is also a very plausible outcome.

  • @Stiasteny
    @Stiasteny10 ай бұрын

    It is glanced over so quickly that Ryan lost his finger tips and got a part of his toes and foot amputated. Wow my heart goes out for him ♥️.

  • @JoyfulNerd400

    @JoyfulNerd400

    7 ай бұрын

    Considering he has sadly passed, I think this was the least of his problems. This entire trial was absolutely horrifically botched, whether by accident, on purpose, the medication simply didn’t work or otherwise

  • @BlackKiryuu

    @BlackKiryuu

    7 ай бұрын

    @@JoyfulNerd400 He died??!! When? As a result of this trial?

  • @JoyfulNerd400

    @JoyfulNerd400

    7 ай бұрын

    @@BlackKiryuu he did end up passing away, yeah. His organs failed and as far as I’m aware his treatment failed in the end

  • @BlackKiryuu

    @BlackKiryuu

    7 ай бұрын

    @@JoyfulNerd400 Oh my God. I feel soo sorry for him! Did his family get any help after his death? Like compensation for damage and what not?

  • @andrewbordeaux1344

    @andrewbordeaux1344

    7 ай бұрын

    @@JoyfulNerd400 Bullshit. A fast Google search leads to a Facebook post from January 2021 saying that Ryan "recently graduated with a First in BSc Economic & Social Policy", and from there one can find a "Birkbeck Events Blog" that states that in 2012 he had a son, in 2016 he started his part-time BSc Economic and Social Policy degree, and that in November (2020) he graduated, winning the prize for the best final year Economics and Social Policy student. Also, judging by you saying "the medication simply didn’t work" and "his treatment failed in the end", you don't even understand what a drug trial is (none of the volunteers needed the drug!). Please avoid saying ignorant and stupid things, everyone reading your comments could end being dumber as a result.

  • @karenbarnes852
    @karenbarnes852 Жыл бұрын

    I found this a very interesting article. My granddaughter had a rare cancer at the age of 2 and ALL of her treatment was through international clinical trials. Part of her treatment was immunotherapy, where one of the risks was a cytokine storm because of the use of monoclonal antibodies. After nearly four years of treatment she is now five years in remission. The harsh treatments she had have left her with a variety of health problems, but she is a happy 10 year old now and very precious to our family. Whilst she has contributed to many clinical trials through her treatments, we are indebted to the children who have gone before her and may have since died of the illness or the treatment. Anyone who contributes to the advance of medicine through participating in clinical trials (of whatever stage) is making a massive contribution to the rest of humanity.

  • @pamsam8933

    @pamsam8933

    Жыл бұрын

    Amen. I agree. And with any trials, all precautions should be taken, and there should ALWAYS be an ESTABLISHED anecdotal plan in case of known, and especially unknown, side affects.

  • @jandoel

    @jandoel

    Жыл бұрын

    The posh doctor interviews between creepypasta-like reenactment scenes is such a mood

  • @sanderson2

    @sanderson2

    Жыл бұрын

    @@pamsam8933 I I IC think ⁹I 99

  • @rylandavis2976

    @rylandavis2976

    Жыл бұрын

    @@pamsam8933 the problem is that you can't know the side effects to 100% certainty in advance. You can inject them into mice and monkeys and test on human cells and determine it "might" be safe. When you are the one taking a drug that no human has taken before, nobody can predict with certainty what is going to happen, it's a big risk and they should (and almost always do) tell you that it is a risk.

  • @Tyler11821

    @Tyler11821

    11 ай бұрын

    The reason things like this are big stories is because of how rare events like this are. The vast, vast majority of first for human clinical trials have the worst problem of people withdrawing due to side effects. This occurs in both the cohort getting the drug and the cohort getting placebo. Multiple fatalities in a single trial is so unusual as to lead to videos like this. The risk is higher in rare illness, where there just fundamentally isn't as much data in. Even then, like in this case, actual death is exceptionally rare.

  • @intothemystic5223
    @intothemystic52234 жыл бұрын

    I've got to stop reading comments while watching documentaries. The amount of times I have to rewind is absurd.

  • @ethank5681

    @ethank5681

    4 жыл бұрын

    into the mystic comment section is better than the vid

  • @overthehedge7591

    @overthehedge7591

    4 жыл бұрын

    @@ethank5681 there would be no comments without the video

  • @EdderzX1

    @EdderzX1

    4 жыл бұрын

    Keep doing the same lmao

  • @reggie6871

    @reggie6871

    4 жыл бұрын

    thanks for the reminder, i wouldve gone 10 minutes deeper without this comment

  • @AdriCr4ft

    @AdriCr4ft

    4 жыл бұрын

    I was thinking the same... lol

  • @StrawberryNinjaNibbles
    @StrawberryNinjaNibbles4 жыл бұрын

    Get this casting director a raise. All these actors look so much like the real people while also being able to actually act

  • @lennysmileyface

    @lennysmileyface

    4 жыл бұрын

    I swear some of them are the actual people. Number 2 was definitely the same guy.

  • @GnosticSeeker369

    @GnosticSeeker369

    4 жыл бұрын

    It’s epic bro Best I’ve seen

  • @StrawberryNinjaNibbles

    @StrawberryNinjaNibbles

    4 жыл бұрын

    Robert Gardea im aware what a re-enactment is... hence why I said props to casting director

  • @nicoleyandle9978

    @nicoleyandle9978

    4 жыл бұрын

    StrawberryNinja Nibbles #mansplaining at its worst-🙄🙄

  • @nicoleyandle9978

    @nicoleyandle9978

    4 жыл бұрын

    StrawberryNinja Nibbles omg you’re right. Without thinking about it, I unconsciously found myself thinking, how did they have video of these people when it was happening Lolol duh

  • @graceaxisa4213
    @graceaxisa4213 Жыл бұрын

    Totally irrelevant, but the dramatization of this event was first class. As a cancer survivor, I am so grateful to anyone who participates in trials. Including the medical staff who take part. I am sorry that these men went through this horrific experience and I am grateful that, despite the dire consequences, new protocols relating to trials have been adopted. Seeing David with his young family was a huge relief ❤️

  • @sylviaking8866

    @sylviaking8866

    Жыл бұрын

    My twin sister nearly died from Covid. The dramatization in this show is similar to what she went through. People next to her who did not make it were wheeled away. She said it was the worst experience of her life. Thank God she survived.

  • @graceaxisa4213

    @graceaxisa4213

    Жыл бұрын

    @@sylviaking8866 oh my goodness, how traumatic for her. I hope she is fully recovered now.

  • @billyballsup2685

    @billyballsup2685

    8 ай бұрын

    There's not enough money to be made giving you a cancer wonder drug. Probably been around hidden for years. Pharmaceutical is a business. It's all about money not your good health.

  • @kellymurphy6667
    @kellymurphy6667 Жыл бұрын

    This is astounding. I'm 24 years in remission from Leukaemia and two years of gruelling chemotherapy treatment I endured from 16 - 18. I imagine at some point each one of the toxins in the specific chemo cocktail I received were one trialled by participants equally as brave as these hero's. And I can say I wouldn't have envied what they put themselves through in doing so either! But I'm beyond grateful they did! Even given the long term ramifications I'll be dealing with from here on in, I wouldn't forsake that for the experience I had knowing what it is to be in love and the pure joy I eventually experienced in giving birth to two gorgeous and extremely precious daughters.

  • @tiredanddepressed

    @tiredanddepressed

    9 ай бұрын

    It's crazy when you think about the fact that healthy people took chemotherapy drugs first to see if it was safe. Knowingly taking the equivalent of a bomb going off in your system since it'll destroy everything in sight is wild

  • @lissakaye610

    @lissakaye610

    8 ай бұрын

    Success stories like you are exactly why I work in research. Every single cancer therapy and Alzheimer’s drug trial I hope not so see any observations or toxicity. It is always very sad when something doesn’t work as intended.

  • @PhoenIXPhantasies

    @PhoenIXPhantasies

    6 ай бұрын

    Not brave but stupid. Usually people in need of money. Your life is worth so much more than money!

  • @nickidaisydandelion4044

    @nickidaisydandelion4044

    3 ай бұрын

    No to pharma.

  • @MiVidaBellisima

    @MiVidaBellisima

    3 ай бұрын

    Congrats to you, and I hope you live to see 103 😊

  • @ROA1988
    @ROA19884 жыл бұрын

    It makes me mad to think that the medication was administered 10 mins apart, rather than 90 mins apart. This could have only been one.

  • @birthdayplant

    @birthdayplant

    4 жыл бұрын

    'Berto O. A. you never know if another person will react the same way to the medication if only one person got the trial. that’s why there’s usually more than one person getting tested

  • @StanslaMichael

    @StanslaMichael

    4 жыл бұрын

    They just wanted to know who got the placebo.

  • @janeyd5280

    @janeyd5280

    4 жыл бұрын

    @@birthdayplant it was never appropriately thought out and therefore that was negligence in a big way.

  • @caseywinchester7639

    @caseywinchester7639

    4 жыл бұрын

    niyah and yet they all reacted the same way

  • @charliebrazier2863

    @charliebrazier2863

    4 жыл бұрын

    niyah yeah and If it went that bad on one person then they wouldn’t do it on another however if one person was fine

  • @matt391
    @matt3914 жыл бұрын

    Everyone else: *screaming in pain* That one dude: *mom come pick me up im scared*

  • @tonypasma1707

    @tonypasma1707

    4 жыл бұрын

    mmm

  • @duck3819

    @duck3819

    4 жыл бұрын

    That guy would be me

  • @MsT-xm8xz

    @MsT-xm8xz

    4 жыл бұрын

    @Saint Beelzebub 😭😭😭

  • @whipchick90

    @whipchick90

    4 жыл бұрын

    「 Cinderblock 」 😂

  • @michaelsmith7328

    @michaelsmith7328

    4 жыл бұрын

    Hahahahs

  • @TheMutantCreeper
    @TheMutantCreeper Жыл бұрын

    I wish we could have had Ryan in the interview. I completely understand that he wouldn’t want to since he went through so much. I just wish we could understand what his life was afterwards.

  • @Monkey-fc9nc

    @Monkey-fc9nc

    8 ай бұрын

    He probably can't due to settling litigation out of court.

  • @kirin1230

    @kirin1230

    8 ай бұрын

    I wouldn't want my life broadcasted online either... but I wish him the best

  • @tshs1663

    @tshs1663

    7 ай бұрын

    ryan died actually

  • @Patricksbenzowithdrawal

    @Patricksbenzowithdrawal

    7 ай бұрын

    @@tshs1663 according to who?? Simple google search says absolutely nothing about him dying. He nearly died during his 4 months in hospital but he is very much alive after this horrific experience

  • @Mangafan47

    @Mangafan47

    7 ай бұрын

    @@tshs1663 source? I googled it, but couldn't find anything regarding him dying.

  • @sadfatdragon9529
    @sadfatdragon95299 ай бұрын

    What honestly surprised me is that it seems like the people running the trails didn't have a plan for if things go horribly wrong.

  • @anglophils645

    @anglophils645

    Ай бұрын

    They do now. And you must remember, nothing like this had ever happened before, during all the decades of drug trials. And this drug had already been tested on animals, with no adverse effects, at much higher doses.

  • @ID_Scarlet

    @ID_Scarlet

    5 күн бұрын

    Also these trials were preformed in presence of medical staff but even with that you cannot predict what immediate and also longterm side effects can occur.

  • @jojoshaw5349
    @jojoshaw53494 жыл бұрын

    me: oh man my knees hurt again *watches documentary * never mind i’m good

  • @johnnybhoff226

    @johnnybhoff226

    4 жыл бұрын

    Joji Jo I love it 😂

  • @Funnymuslimlady

    @Funnymuslimlady

    4 жыл бұрын

    Same

  • @becky2322

    @becky2322

    4 жыл бұрын

    legit me

  • @taffymatt6870

    @taffymatt6870

    4 жыл бұрын

    @@becky2322DM me, you look stunning :)

  • @zZmiLLi

    @zZmiLLi

    4 жыл бұрын

    LMAO

  • @amtf7251
    @amtf72515 жыл бұрын

    Everybody’s screaming in pain and the other dude’s just sitting there

  • @michellemuskeyn329

    @michellemuskeyn329

    4 жыл бұрын

    He’s soooo lucky 🍀!

  • @lorenzolatino7023

    @lorenzolatino7023

    4 жыл бұрын

    @@Timeless80 Haha, I was about to say that.

  • @dangerousbuterax6891

    @dangerousbuterax6891

    4 жыл бұрын

    i would’ve hated to be him. imagine everyone around you screaming in pain... terrifying

  • @LF-lv4ov

    @LF-lv4ov

    4 жыл бұрын

    @@dangerousbuterax6891 i'd rather be him than the ones that actually took the drug

  • @mlim6927

    @mlim6927

    4 жыл бұрын

    @@LF-lv4ov same he's lucky

  • @patsysolatzzo2962
    @patsysolatzzo29628 ай бұрын

    While nobody deserves the outcome of this particular medical trial, it’s an incredibly brave and selfless act to anyone who needs medicine and even to the lives that are forced into trials like animals. It’s scary but to think of all of the lives and families this event has saved. I’m so sorry to everyone involved but the gratitude I have for such people is incredible.

  • @niamphdollieofficial

    @niamphdollieofficial

    4 ай бұрын

    I'm sure they instantly regretted it lol

  • @tracy1394
    @tracy13947 ай бұрын

    I was in labor with my first baby and the pain was absolutely horrible. My husband said that I tried to get out of bed and leave. I truly believed that if I could just leave the room that I would be pain free.

  • @Strawberrymerit

    @Strawberrymerit

    3 ай бұрын

    Wording is a bit off

  • @skylarstarr3973

    @skylarstarr3973

    Ай бұрын

    I tried this too. 😂 Funny now but at the time I was in so much pain and I was so scared. I told my husband I just needed to get out of the room and out of the hospital then I'd be ok. He was compassionate but also amused and said something like "but what about the baby? If you leave you still have to give birth." 😂 I don't know, man.

  • @AppleYou
    @AppleYou4 жыл бұрын

    Part 1: company brings patients to trial. Part 2: patients bring company to trial.

  • @FreeAmerica4Ever

    @FreeAmerica4Ever

    4 жыл бұрын

    If only it was that easy

  • @lhaviland8602

    @lhaviland8602

    4 жыл бұрын

    And loose!

  • @underestimatedsmilin2429

    @underestimatedsmilin2429

    4 жыл бұрын

    AppleYou Brilliant comment!

  • @johnimusic12

    @johnimusic12

    4 жыл бұрын

    I'm sure the patients signed away any probability of liability

  • @saganord9859

    @saganord9859

    4 жыл бұрын

    Uno reverse card

  • @ravenryder6241
    @ravenryder62415 жыл бұрын

    For those of you making fun of the doctor for asking if they're okay, it's actually a very good practice. First of all, he's making sure they're still responsive. Second of all, he's trying to keep them calm. If you saw someone crack their skull open, you wouldn't start shouting "OMG ARE YOU OKAY!? OH MY GOD HE'S GONNA DIE THAT'S A LOT OF BLOOD" no, you'd say "It's going to be okay, you'll be fine." Just so you know

  • @toddhoward5749

    @toddhoward5749

    5 жыл бұрын

    lmao some doctor (well, nurse) screamed "OH MY GOD THAT'S A LOT OF BLOOD!!!" when I threw it up once, thought I was gonna die

  • @ravenryder6241

    @ravenryder6241

    5 жыл бұрын

    Index III is OUT my point exactly

  • @Caperhere

    @Caperhere

    5 жыл бұрын

    Raven Ryder I don’t know why Parexel claimed to have no knowledge of their responses, but the pharma doctor read in the literature supplied by Parexel that their reactions were thought to happen rarely.

  • @Wiplash12345

    @Wiplash12345

    5 жыл бұрын

    *aRe YoU oKaY*

  • @jsesheadphonesset6963

    @jsesheadphonesset6963

    5 жыл бұрын

    (OMG YOUR DEAD i mean) its fine ur gonna be okay:)

  • @mambutuomalley2260
    @mambutuomalley22607 ай бұрын

    "I was really down... the worst down" - That's such a chilling phrase.

  • @toni4729
    @toni4729 Жыл бұрын

    I can't help crying for Ryan. What a life for a young man..

  • @user-kz4ke8mg4r

    @user-kz4ke8mg4r

    2 ай бұрын

    What about the victims in the world's largest and latest drug trial? 😉💉

  • @julianbell9161
    @julianbell91615 жыл бұрын

    The worst part was how quickly they dosed everyone. They first guy is in a cold sweat and writhing in pain, and while this is going on they are dosing the guys in the other room.

  • @kristie-leecorney7388

    @kristie-leecorney7388

    5 жыл бұрын

    Julian Bell Mark R what was this drug trial for ? what the heck was the drug trial for because all those people were 100% healthy and had nothing to cure , So do you think , is it really a cure they were looking for or is it a way to make people sick to cut down the population , the government plan ?

  • @bageda3109

    @bageda3109

    5 жыл бұрын

    They should have waited way longer for each person getting injected and they should have given a way smaller dose to check how they reacted to it

  • @pepsimax48820

    @pepsimax48820

    5 жыл бұрын

    @@kristie-leecorney7388 lol

  • @Jellybellyirish

    @Jellybellyirish

    5 жыл бұрын

    @@kristie-leecorney7388 can see that you didn't watch the documentary, so you'll come up with ingenious conspiracy theories. Get out.

  • @saras.7928

    @saras.7928

    5 жыл бұрын

    Kristie-lee Corney This isn’t a conspiracy video. If the government wanted to cut down on the population they wouldn’t have tested the drug, they would have given it to the patient so they could die.

  • @gugumasango1802
    @gugumasango18025 жыл бұрын

    Doctor: How we doing David? David: Screams with agony and discomfort

  • @FabTasticBoi

    @FabTasticBoi

    5 жыл бұрын

    Me when my mom wakes me up for school

  • @old-yd2kp

    @old-yd2kp

    5 жыл бұрын

    flamingwolfgaming 101 disrspectful but true

  • @Insomniyuh

    @Insomniyuh

    5 жыл бұрын

    Ikr

  • @FabTasticBoi

    @FabTasticBoi

    5 жыл бұрын

    @@old-yd2kp My bad

  • @sqwertt8605

    @sqwertt8605

    5 жыл бұрын

    Doctor : seams ok to me

  • @daddydancer1555
    @daddydancer15557 ай бұрын

    Poor guys i hope they have managed to deal with the PTSD from this event. This is not something you can get over easily.

  • @KyleEvra

    @KyleEvra

    7 ай бұрын

    Agreed. I don't blame them from being very weary about man made medicine.

  • @20PINKluvr
    @20PINKluvr7 ай бұрын

    This is probably why clinical trials span a few months rather than a few days

  • @HP-cn4sd
    @HP-cn4sd5 жыл бұрын

    Omg. Kid was 19 and saving up for driving lessons and now he has no fingers

  • @dylanp7817

    @dylanp7817

    5 жыл бұрын

    Gavin Haase 47:09

  • @shyshy8788

    @shyshy8788

    5 жыл бұрын

    He lost all his toes and parts of fingers. The tips

  • @nickhiggins1091

    @nickhiggins1091

    5 жыл бұрын

    He can still drive. My mother had crippling arthritis, and could not hold the steering wheel, just guide it with her palms, and turned with her elbows. He only lost the tips. Not the whole fingers. Yes, it is a tragedy he suffered. So did my mother. She still made do. Reiterate, he CAN still drive.

  • @ninjasneaks1472

    @ninjasneaks1472

    5 жыл бұрын

    I mean he could still drive? But they didnt specifically say what exactly happen to ryan..

  • @shyshy8788

    @shyshy8788

    5 жыл бұрын

    @@nickhiggins1091 doesn't sound safe at all. That's why in your driving test you have two hands on the wheel. Not your elbows

  • @sarahvela4354
    @sarahvela43544 жыл бұрын

    Who else watched this, and immediately decided to never participate in a clinical trial? 🤯🧐

  • @richardblackhound1246

    @richardblackhound1246

    4 жыл бұрын

    I heard about this at the time it happened and then decided the same. Your life and health isn't worth playing Russian roulette with. Even if nothing like this happens to you, you don't know what unknown long term effects might be caused.

  • @Ashley-on4ln

    @Ashley-on4ln

    4 жыл бұрын

    Sarah Vela I have participated In one! Nothing happened to me thank goodness lol

  • @Jaxon0098

    @Jaxon0098

    4 жыл бұрын

    Where did you participate in your study at ?

  • @Jaxon0098

    @Jaxon0098

    4 жыл бұрын

    @Poppy Mystique I'm in a study right now in the states at a place called PRA Health Sciences in Lenexa, Kansas City, Kansas My study right now is 5 days for $3,000 us

  • @sarahvela4354

    @sarahvela4354

    4 жыл бұрын

    I had considered cosmetic trials, but after this there is no amount of money in the world that could make me want to participate. Just to risky for me.

  • @cherylmailloux9647
    @cherylmailloux96479 ай бұрын

    Animal testing is cruel too!! At least humans volunteer animals have NO CHOICE!!!

  • @LostVindication
    @LostVindication9 ай бұрын

    I was once in the hospital for some testing and they tried me on a new medication. I instantly had a bad reaction and the whole situation was super traumatic and to this day I am afraid to try new meds. Lot of the first symptoms these men described I went though but no where near as bad. I was in the hospital afterwards for almost 2 week and it took me almost 4 months to fully recover. This breaks my heart.

  • @lucygoosie7726

    @lucygoosie7726

    6 ай бұрын

    I once had an anaphylactic reaction to an antibiotic, now I’m terrified of taking any medication. I have a lot of allergies and I’ve had reactions to multiple different meds, but that was the scariest. Trauma is not something to take lightly, it can be debilitating.

  • @venda.havelka

    @venda.havelka

    5 ай бұрын

    When I was sick with rather severe tonsillitis, I've had Doumox (amoxiciline) administered and got a terrible rash all over my body in some 24 hours after first dose. It scared my GP so much she got our national drug administration involved and it eventually sparked a Europe wide investigation by EMA on the drug (mainly because rash was not on the list of known side effects at the time). My rash got better in like a week and I eventually recovered from the tonsillitis just to be completely astonished by all the internetional fuss I caused. I still have amoxiciline allergy written in big red letters on my folder in the GP's pacient registry to this day...

  • @floofytown
    @floofytown5 жыл бұрын

    This reenactment is SO WELL DONE. Holy crap.

  • @lalala-vk7ex

    @lalala-vk7ex

    5 жыл бұрын

    Ikr!! I had to go back to the beginning of the video to find where it said it was reenactment I was like damnn

  • @susanfoley8360

    @susanfoley8360

    5 жыл бұрын

    They found actors who look incredibly like the real people involved.

  • @alexanderplatzberlin3940

    @alexanderplatzberlin3940

    5 жыл бұрын

    Yes. I totally forgot that it wasn´t real while watching … :D

  • @sleepyidiot2010

    @sleepyidiot2010

    4 жыл бұрын

    Susan Foley are all of them actors? I straight up thought one of them (the placebo guy watching everything go down) was the actual person

  • @xposed11

    @xposed11

    4 жыл бұрын

    You believe this? They gave clinical trial medication, as a test...to humans with nothing to actually cure.. it was meant to cure leukemia....which these random people did not have

  • @nicoleslaughter7983
    @nicoleslaughter79834 жыл бұрын

    I noticed they never talked about the eighth man, I looked him up and he’s wheel chair bound and had his fingertips fall off too. How unfortunate for all of them.

  • @sarahmai5902

    @sarahmai5902

    4 жыл бұрын

    Wow

  • @joyful_tanya

    @joyful_tanya

    4 жыл бұрын

    Thank you for looking that up for us all!

  • @janekeller3791

    @janekeller3791

    4 жыл бұрын

    what did you look up to find it?

  • @flowerfaerie8931

    @flowerfaerie8931

    4 жыл бұрын

    Nicole Slaughter ...It mentions what happens to him right there in the video.

  • @wiktoriagwozdowska5484

    @wiktoriagwozdowska5484

    4 жыл бұрын

    any link or name of the man so i could search it pls :) its very scary docu really if i could i would wish for this to never happen :(

  • @LynetteTheRogue
    @LynetteTheRogue Жыл бұрын

    I'm surprised that they didn't have more doctors overseeing this trial considering how fast it all went sideways. You think they would be more prepared for that with it considering it was an experimental drug trial

  • @potocatepetl

    @potocatepetl

    7 ай бұрын

    Oh, you'd be surprised how low the requirements for trials are.... I wish I didn't know as much as I've learned in the last 5 years. One can only hope to have the luck of being and staying healthy.

  • @jenniferfriesen7691

    @jenniferfriesen7691

    4 ай бұрын

    The NIH didn’t even know they were doing this trial until the hospital called for help!

  • @autdelux
    @autdelux7 ай бұрын

    "there is no rulebook for such a case" makes me shiver

  • @preciousj6931
    @preciousj69314 жыл бұрын

    Those 2 men won a LOTTERY called PLACEBO

  • @tatendamurena3498

    @tatendamurena3498

    4 жыл бұрын

    precious lol

  • @orchdork775

    @orchdork775

    4 жыл бұрын

    @@sunandmoon139 That's not actually what it is. It's when a person experiences a decrease in symptom severity, because they believe they are receiving medication. The placebo effect does not cure illnesses, it just helps to relieve symptoms.

  • @orchdork775

    @orchdork775

    4 жыл бұрын

    @@sunandmoon139 It has to do with believing that you are receiving a treatment that will make you feel better. I reccomend that you look up some examples and/or articles about it on google, as it's actually quite fascinating. There is also the nocebo effect, which is when a person believes a treatment will have negative side effects, so they end up experiencing those side effects simply because they expected to experience them. There have been trials done where one group of people is give sugar pills (though the trial participants were told it was real medication) and were not warned of any potential side effects, while the second group received the same placebo pills, but were told a list of potential side effects they might experience. The people in the second group reported experiencing those side effects at a much higher rate than people in the first group. By believing they might feel unwell, the trial participants actually caused themselves to feel sick. It really goes to show how much your mindset can effect you. This even manifests psychologically as well. For example, if you believe that you won't ever succeed, chances are you will have a lessened ability to perform tasks, low motivation, and little dedication. One of the biggest effects would be that you stop trying, and that you never actually put 100% into something. I mean, why bother putting your all into something if you are sure you will fail?? Alternatively, if you believe that you could be very successful, you would likely take way more opportunities, work harder and put more effort into things, have high motivation, and be very dedicated. These changes in behaivor have a serious effect on your life, and could actually cause someone to fail at things simply because they are convinced they aren't capable of succeeding. This is called fortune telling in psychology, if I remember correctly. I'm very guilty of doing this myself, actually. It's harder than it sounds to let go of all the negative beliefs one has about themselves and start believing in themselves all of the sudden. It's really hard, and at this point I actually fortune tell about fortune telling. I know that I do it a lot, so I end up doing it even more simply because I expect myself to. It's maddening 😂😭

  • @zangetsuu

    @zangetsuu

    4 жыл бұрын

    @@sunandmoon139 it has nothing to do with religion if that's what you're asking, although those words can be used in a spiritual context. if that's not what you meant ignore me haha

  • @filmmade6214

    @filmmade6214

    4 жыл бұрын

    Comment war

  • @muffinman5741
    @muffinman57415 жыл бұрын

    "No one's gonna die right?" "Well, we'll see" well at least he was honest

  • @TheMausymaus

    @TheMausymaus

    5 жыл бұрын

    That part made me laugh so hard

  • @Deezhan

    @Deezhan

    5 жыл бұрын

    "We'll see... Well... I'mean I will see. In case you, ... you know."

  • @katerickard2804

    @katerickard2804

    5 жыл бұрын

    followed by evil cartoon villain cackle lol

  • @O7ghostX

    @O7ghostX

    4 жыл бұрын

    yeah doctors cannot affirm things they don't know or they might be charged with lies

  • @user-jg6bu3hc8f
    @user-jg6bu3hc8f Жыл бұрын

    The actor who played as the Doctor really had me stressed out as well, he did a great job. Everyone did

  • @philbarone4603
    @philbarone46032 ай бұрын

    In the last few years I’ve discovered just how much doctors don’t know what they’re doing.

  • @vallivergano239

    @vallivergano239

    2 ай бұрын

    💯

  • @starthejar1419
    @starthejar14193 жыл бұрын

    Everyone: puking, screaming, dying That one guy: okay think imma head out ✌️

  • @harssamoanlal2947

    @harssamoanlal2947

    3 жыл бұрын

    @Jimo National ok boomer

  • @rickastleyisnevergonnagive5673

    @rickastleyisnevergonnagive5673

    3 жыл бұрын

    @Jimo National ok snow roach

  • @emip4669

    @emip4669

    3 жыл бұрын

    @Jimo National and this is a problem because...

  • @bettyjanemaynard2269

    @bettyjanemaynard2269

    3 жыл бұрын

    @@harssamoanlal2947 kip

  • @jaydon7819

    @jaydon7819

    3 жыл бұрын

    @Jimo National apespeak isn’t a real word either 💀 what a mong

  • @soapz.
    @soapz.4 жыл бұрын

    everyone: throwing up, screaming that one dude sitting: alright ima head out

  • @soapz.

    @soapz.

    4 жыл бұрын

    Megan Khadka it’s like... i didn’t know that

  • @anncommanda2060

    @anncommanda2060

    4 жыл бұрын

    He was a control/ placebo

  • @lulumce6281

    @lulumce6281

    4 жыл бұрын

    When was that? Just so I can skip a sis is scared of sick

  • @zhipeizhou5582

    @zhipeizhou5582

    4 жыл бұрын

    B lasagna

  • @counter_cris6371

    @counter_cris6371

    4 жыл бұрын

    anna commanda what does that mean?

  • @Emy53
    @Emy537 ай бұрын

    Had this been done on animals, they would have suffered more intensely because they can't speak and tell you what they are feeling.

  • @jennifermuse9154

    @jennifermuse9154

    3 ай бұрын

    So sad. Kills me to think about

  • @MachallaNaNaNa

    @MachallaNaNaNa

    Ай бұрын

    It was done on animals before the human trials. The animals didn't have this kind of reaction

  • @lilmissjoodypoody

    @lilmissjoodypoody

    Ай бұрын

    @@MachallaNaNaNawell, not the last batch before it went to human trials. To establish dosage, they would have kept pushing it higher until they elicited negative side responses to determine the maximum. That also informs them of what potential side effects and reactions they can expect. Unfortunately, many animals would have suffered to get to the human trials stage, not to mention all the ones that had such horrendous reactions that it never reached human trials. And even if they didn’t suffer direct side effects from the drug itself, they would have been caged and poked and prodded, with multiple blood extractions and perhaps biopsies as well as some animals euthanised in order to open them up to see the histological changes to their bodies as a result of the substance. They wouldn’t have been kept in humane habitats. It’s a huge problem with how we develop an understanding of disease and treatments. I don’t have the answers but I am well aware of the price of our health on other animals.

  • @greenbrain8725
    @greenbrain87257 ай бұрын

    Can we take a moment and acknowledge how horrible it is that we must subject animals (macaques in this case) routinely to these horrible experiments, and after a life of horrendous isolation and suffering, these animals are simply discarded like garbage.

  • @diannbajewicz8952

    @diannbajewicz8952

    7 ай бұрын

    So what are they suppose to do to help people then give them a solution then

  • @srccde

    @srccde

    7 ай бұрын

    Yeah it's horrible but there's no other way.

  • @crazyvida2091

    @crazyvida2091

    6 ай бұрын

    Our lives aren't above animal lives.

  • @user-br9br2dk4n

    @user-br9br2dk4n

    6 ай бұрын

    Look up Dr hadwin / Animal free research charity it is possible

  • @helenl44

    @helenl44

    5 ай бұрын

    I agree. I watch the TV show about Monkey World in Dorset, UK (on KZread under Beyond Wildlife) where many of the primates came from laboratories and now get to live their lives at the sanctuary with other primates, the right food and the ability to go outside, play, etc. I noticed that the monkeys which appeared in the documentary were squirrel monkeys, but the narratives mention macaques.

  • @pharmacyman6415
    @pharmacyman64154 жыл бұрын

    Placebo guy: reading his book Guy next to him: in horrible pain Placebo guy: *chuckles I’m in danger*

  • @sgtrexy1479

    @sgtrexy1479

    4 жыл бұрын

    Ralph wigam

  • @EmilySimpson723
    @EmilySimpson7233 жыл бұрын

    That moment when you realize only three of the eight people are in the documentary ...

  • @imjustchilling4477

    @imjustchilling4477

    3 жыл бұрын

    Nononoooo

  • @imjustchilling4477

    @imjustchilling4477

    3 жыл бұрын

    That... no

  • @secnytsecnyt2981

    @secnytsecnyt2981

    3 жыл бұрын

    I am fairly sure they all survived, though someone can correct me if I’m wrong. More likely, they couldn’t get in contact with the others, or they weren’t interested.

  • @lorinagosso

    @lorinagosso

    3 жыл бұрын

    Lawsuits, NDA agreements.

  • @lovelovelovexo

    @lovelovelovexo

    3 жыл бұрын

    Yes very strange. I wonder how the boy is doing who lost his fingertips and a few of his toes

  • @RocksWA
    @RocksWA8 ай бұрын

    I met a guy in London in 1996 who lost all his hair from drug trials. Even then I couldn't believe any one would volunteer for this

  • @elsarm178
    @elsarm1787 ай бұрын

    Once I took some medicine to treat heavy allergy, the name is Xyzall. I never felt so horrible, I became deaf for 1 week, had nose bleeding and I was paralyzed for 8 hours. I can’t imagine some people went though the medical trial with that crap, and why it is not discontinued. That was a very scary experience.

  • @potocatepetl

    @potocatepetl

    7 ай бұрын

    Did you check the articles they most likely published? Were all the side effects you had mentioned? Or are you aware of any other trials they did after yours? Having a trial doesn't automatically mean that the drug is put in a short term on the market. There might be a need for the drug or the method of administration to be changed... One needs a trial to find out how exactly a drug works on people and if and what is wrong...

  • @patrickmcpartland1398

    @patrickmcpartland1398

    7 ай бұрын

    ​@@potocatepetlno no no don't you see? It took some allergy medicine so he's an expert in pharmacology and clinical trials.

  • @anoukkroolvink1397
    @anoukkroolvink13974 жыл бұрын

    They talk about how a lot of the man got back to “normal” but still one guy lost just fingers and a foot and his life was never the same

  • @desolationangel5136

    @desolationangel5136

    4 жыл бұрын

    You should also watch the thalidomide documentary on youtube. kzread.info/dash/bejne/aKmd3NismcSuqdo.html

  • @spvillano

    @spvillano

    4 жыл бұрын

    Not a one of them went back to normal, their immune systems are fouled up to this day.

  • @thedopeexperiment

    @thedopeexperiment

    4 жыл бұрын

    Yeah I wanna know more about Ryan.

  • @BS-dq1kz

    @BS-dq1kz

    4 жыл бұрын

    And his penis. So there’s that. Pretty significant if you ask me.

  • @thedopeexperiment

    @thedopeexperiment

    4 жыл бұрын

    @@BS-dq1kz is that true?what a shame & he was the youngest of the group, not that it would suck any less happening to any of the others.

  • @bonniera3819
    @bonniera38194 жыл бұрын

    They all must have some form of PTSD from going through that

  • @ava-tb3cw

    @ava-tb3cw

    4 жыл бұрын

    With a phobia of medication, needles and that i suppose

  • @bonniera3819

    @bonniera3819

    4 жыл бұрын

    Well they nearly died that's pretty traumatic in itself

  • @robertbunton6394

    @robertbunton6394

    4 жыл бұрын

    Yea thats for sure

  • @taunjabrockway6760

    @taunjabrockway6760

    4 жыл бұрын

    Well then, they now should be advocates for banning all animal testing since they know the horrors.. but they had it WAAAY better than the animals that are still being tortured

  • @cailumwolf1616

    @cailumwolf1616

    4 жыл бұрын

    Taunja Brockway but if animal testing had happend it would be different

  • @bliven8704
    @bliven87048 ай бұрын

    As a mom whose daughter is making progress against pancreatic cancer we were originally told don’t bother with chemo, it won’t work, enjoy your last 7 months, thank you to all who sacrifice in hope to help others.

  • @kimmead3683
    @kimmead36833 ай бұрын

    This is why I don't do trials. I did one and I had the symptoms of malaria. Never again.

  • @possiblyelle
    @possiblyelle3 жыл бұрын

    His fingertips fell off!! They weren't even amputated! Imagine just laying there watching your fingertips FALL OFF!!! I feel so bad for those men...

  • @possiblyelle

    @possiblyelle

    3 жыл бұрын

    @jorge rodi Ohhhhh I'm dumbbbb I got so freaked out!!

  • @logicss2893

    @logicss2893

    3 жыл бұрын

    Bruh

  • @kells8241

    @kells8241

    3 жыл бұрын

    @jorge rodi please use your inside voice

  • @jonnyb.animationstutorials7119

    @jonnyb.animationstutorials7119

    3 жыл бұрын

    Necrosis is the term for Dying tissue. This is why I think this was blood poisoning. Necrosis can occur when the blood isn't healthy enough to provide the flesh nutrition, and the cells in the tissue die.

  • @miriamllamas224

    @miriamllamas224

    3 жыл бұрын

    @jorge rodi Capital letters means you're shouting. So low your voice 🤗 and be caring.

  • @kandeejohnson
    @kandeejohnson3 жыл бұрын

    ME, thinking I'm going to only watch 5 minutes of this and end up watching the whole thing!

  • @kylieskaggs1444

    @kylieskaggs1444

    3 жыл бұрын

    Sammmme girl

  • @dorametasimpson4985

    @dorametasimpson4985

    3 жыл бұрын

    This really does intrigue me .

  • @dorametasimpson4985

    @dorametasimpson4985

    3 жыл бұрын

    God Is So Merciful .. Amen .

  • @dorametasimpson4985

    @dorametasimpson4985

    3 жыл бұрын

    No amount of $$$$$ ... Is worth playing the , maybe , or , maybe not day !!! Which is a memory of , I'm alive !

  • @reyno6826

    @reyno6826

    3 жыл бұрын

    Same! 😬

  • @Courtneyemily91
    @Courtneyemily914 ай бұрын

    I’d be freaking out as soon as the first guy started to have some severe effects. Omg…

  • @monkeynumbernine
    @monkeynumbernine Жыл бұрын

    It's insane that they didn't stop the dosing when they saw that it was going so wrong.

  • @circlingoverland4364

    @circlingoverland4364

    7 ай бұрын

    I'm sure they thought that the drug would be safe and effective

  • @lenitaa7938

    @lenitaa7938

    7 ай бұрын

    I think they gave the whole dose at once, fast, which was a mistake on their part!! It was too late to stop, as I understood it!

  • @patricknein9062
    @patricknein90623 жыл бұрын

    If this would have happened in America, they would have been stuck with the medical bill as well.

  • @AlucardRawks

    @AlucardRawks

    3 жыл бұрын

    @@Tyler-zw4kq just because a law suit is won doesn't mean they ever see the money

  • @hellaSwankkyToo

    @hellaSwankkyToo

    3 жыл бұрын

    big facts. good ole american health“care.”

  • @samsamthetrashcan

    @samsamthetrashcan

    3 жыл бұрын

    Lol accurate

  • @patricknein9062

    @patricknein9062

    3 жыл бұрын

    @AL Cats They absolutely would have. It's the American way. Oh and when you write a sentence calling people stupid, make sure it isn't two sentences crammed into one.

  • @susanjoynes6395

    @susanjoynes6395

    3 жыл бұрын

    @AL Cats I don't know . you tell us. How do you.

  • @eddstudd
    @eddstudd4 жыл бұрын

    This should be a Netflix documentary

  • @raiden961

    @raiden961

    4 жыл бұрын

    It should be that would be amazing

  • @rph_redacted

    @rph_redacted

    4 жыл бұрын

    This could be on House MD or the good doctor

  • @9852323

    @9852323

    4 жыл бұрын

    It’s better on KZread.

  • @makarti2158

    @makarti2158

    4 жыл бұрын

    Nah, KZread's where it's at.

  • @missy_vicky469

    @missy_vicky469

    4 жыл бұрын

    There is a indie style horror movie made based on this, wouldn’t recommend it.

  • @kris2455
    @kris24554 ай бұрын

    They knew about the headache and pain and still injected the last patients. It's hard to comprehend.

  • @joe1071
    @joe10713 ай бұрын

    As a healthcare professional that works in a hospital, this is an absolute nightmare all the way around. Everyone lost in this one

  • @user-ui8sp5th4g
    @user-ui8sp5th4g4 жыл бұрын

    Imagine being one of the ones that got the medicine and being right behind the guy showing the first symptoms. That would be terrifying. He starts screaming and you have to wait until it happens to you. Talk about a horror movie.

  • @MsT-xm8xz

    @MsT-xm8xz

    4 жыл бұрын

    😩

  • @ryanblack3285

    @ryanblack3285

    4 жыл бұрын

    I'd rip the IV out b4 it was my turn. Not worth 2k.

  • @ThatFuckinGame

    @ThatFuckinGame

    3 жыл бұрын

    @@ryanblack3285 apart of the 2k, you would get in a lot of legal trouble, you signed a contract. also by the time the first severe symtphoms showed up, the drug was already administered on everybody.

  • @liofotia
    @liofotia5 жыл бұрын

    Doctor: How are we doing, David? David: *screams into the 5th dimension*

  • @normalhuman78-53

    @normalhuman78-53

    5 жыл бұрын

    heiress of stupidity more like weirdly cut moans

  • @u.s.n.retired1995

    @u.s.n.retired1995

    4 жыл бұрын

    I was thinking the same thing. The patient is clearly in distress and a great deal of it!!

  • @teknacious

    @teknacious

    4 жыл бұрын

    lmfao best comment

  • @breonawarren1507

    @breonawarren1507

    4 жыл бұрын

    Valincia Pruitt They ask anyways to make sure you can respond. Yeah you aren’t doing good but are you responsive?

  • @teariet.tekken-wolffenn5881

    @teariet.tekken-wolffenn5881

    4 жыл бұрын

    That's what I thought.

  • @Courtneyemily91
    @Courtneyemily914 ай бұрын

    The major issue was the drug being administered to every man within minutes of one another instead of adopting a wait and see approach, which you think would be standard initially in a first in man trial. Side note: David’s family is beautiful! So happy to see that.

  • @juditmlnr

    @juditmlnr

    2 ай бұрын

    While that's clearly the case, it seems they still have done everything according to protocol, haven't they? At least they say that in the documentary, so it may not have been standard at the time?

  • @Courtneyemily91

    @Courtneyemily91

    2 ай бұрын

    @@juditmlnr you would think it’d be common sense though. A drug that’s never been given to humans before and they’re rapidly dosing everyone before any side effects are able to take effect. Live and learn, I guess. I’m just glad it wasn’t at the expense of someone’s life.

  • @divinesunshine1881
    @divinesunshine18815 ай бұрын

    My question is, Why would they give a drug that fights off Cancerous cells and such, to perfectly healthy people? I would think this style of study would be given to a person who has an underlying illness. To see if the drug is effective in fighting off that illness.

  • @tbjorn7374
    @tbjorn73744 жыл бұрын

    My first Chemo infusion took over 13 hours to complete. These men were given a full infusion in 10 minutes...That is crazy!

  • @johnbasiglone1219

    @johnbasiglone1219

    4 жыл бұрын

    How are you doing? I hope you are doing well. I sincerely mean that.

  • @gg-sc6gy

    @gg-sc6gy

    4 жыл бұрын

    @@sabitrakhadka8397 wtf is wrong with you

  • @kungfreddie

    @kungfreddie

    4 жыл бұрын

    @@gg-sc6gy 1st time internetting?

  • @gg-sc6gy

    @gg-sc6gy

    4 жыл бұрын

    @@kungfreddie yeah i made it 29 years and never once did I discover it until today

  • @kungfreddie

    @kungfreddie

    4 жыл бұрын

    @@sabitrakhadka8397 swedish

  • @cn8299
    @cn82994 жыл бұрын

    Patient: No one is going to die right? Doctor: Who's your favorite Avenger? Just wondering..

  • @kandyburra

    @kandyburra

    4 жыл бұрын

    Patient: I prefer DC Doctor: yeah im just gonna give you another dose

  • @latoyalegemah787

    @latoyalegemah787

    4 жыл бұрын

    😂😂

  • @silviathesylveon9866

    @silviathesylveon9866

    4 жыл бұрын

    I don't feel so good doctor

  • @pinkdoughnutproductions2517

    @pinkdoughnutproductions2517

    4 жыл бұрын

    I like how these reply’s are taking the joke in so many different ways

  • @vantillex6551

    @vantillex6551

    4 жыл бұрын

    HA

  • @Katsofin
    @Katsofin Жыл бұрын

    I have a close relative who has to take anti leukemia drugs, I am very thankful to those absolutely healthy people who take such risks and help the science to create safe medications

  • @edwardtrezza8129

    @edwardtrezza8129

    Жыл бұрын

    Doctors not care about their patients

  • @chip736

    @chip736

    Жыл бұрын

    @@edwardtrezza8129 if doctors don't care about their patients then how come they try their hardest to save their patients? But yes there are some bad doctors out there don't get me wrong, being a doctor is not for the weak.

  • @childofcascadia

    @childofcascadia

    7 ай бұрын

    @edwardtrezza8129 Huh? You making a blanket statement like that leads me to believe you're an ignorant fool.

  • @india1422
    @india14223 ай бұрын

    I'm a former nurse and i remember hearing about this at the time. As i remember it they essentially gave all the patients the drug basically ask at once

  • @punkyshrewster2736
    @punkyshrewster27363 жыл бұрын

    The saddest patient death I've ever dealt with was a man who had an unexpected allergic reaction to a psoriasis medication we were testing. He was a healthy guy in his early 50s. No one had any reason to believe he wouldn't be going home to his family the next day with some Christmas shopping money in his pocket. It was really a huge shock to everyone, especially his wife and kids.

  • @rubi_4

    @rubi_4

    3 жыл бұрын

    I wish I wouldn't have read this.. Now I'm sad....I could only imagine how the wife and kids felt..

  • @Plaksa2004

    @Plaksa2004

    3 жыл бұрын

    That is something you should understand taking any drug, isn't it? Let alone the one that was never tested on humans, no one knows whether it is safe and that's exactly the risk they are paid for.. If it was safe (and none of the drugs are just cause of the personal reactions anyway) there wouldn't be a need in testing it..

  • @TheRight-handedStranger

    @TheRight-handedStranger

    3 жыл бұрын

    The people are lured by money like the 50 years old man that sadly lost his life. When you are 50 YO with family of your own, it’s not advised to take a trial test. Unfortunately he probably needed the money.

  • @hezekiawhite8207

    @hezekiawhite8207

    3 жыл бұрын

    This is the devils medicine now learn natural medicine.

  • @trafficjon400

    @trafficjon400

    3 жыл бұрын

    Just him? its a lot worse than you think be hind closed doors .

  • @barbarapearse8453
    @barbarapearse84538 ай бұрын

    My husband had multiple myeloma. He did every thing possible. His last chance was a car T cell transfusion. About three weeks after the infusion, he started to decline. Started at the bottom with his feet and not being able to walk and progressively worse, higher and higher. Eventually needing intubation. Eventually, he had progressive encephalopathy. About three weeks later, we took him off life support. Reading his discharge summary, I got a copy and it says his trial was complicated by grade one cytokine release syndrome. Funny thing is that it destroyed his multiple myeloma cancer.

  • @janedoe12

    @janedoe12

    8 ай бұрын

    omg, so sorry...

  • @barbarapearse8453

    @barbarapearse8453

    8 ай бұрын

    The Car T cell was a trial of some kind. I also learned post is that he was first one to be on the trial. FAIL. I do get trials getting to future medicine and he had given a courageous 13 year fight. It was time. It just all declined very quickly.

  • @theaterkitkat
    @theaterkitkat8 ай бұрын

    I’m 18 years old and have four autoimmune diseases, Lupus, ITP, APS and vasculitis. I receive infusions of Rituximab to keep my immune system in check. All I can say? I have great respect and appreciation for all the people who put themselves at risk for the process of creating these kinds of drugs and treatments! The meds I’m on, although highly unpleasant, are the reason I’m alive. Thank you to all of the trial participants and the scientists who are working on development of them!

  • @ReineDeLaSeine14

    @ReineDeLaSeine14

    7 ай бұрын

    Rituxan saved me. I hope you’re doing okay.

  • @michaelwhite7288
    @michaelwhite72883 жыл бұрын

    This is the second time I watched this video, what a horrific trial these wonderful men went through, my daughter was diagnosed with leukemia at age 10 with other complications. Without brave people like these, my daughter would not be a alive today. This Was back in 2001. My sarah is doing well today. My only child. I owe it to brave people like the ones in this document. Thank you so very much from the bottom of my heart. Thank you. Mike, from Richmond, Virginia

  • @lorinagosso

    @lorinagosso

    3 жыл бұрын

    That's great. But everyone that I know that had leukemia and was treated for it , died. They spent years of their life receiving agonizing treatment that was meant to save them, costing thousands. They would be in remission, like they were cured, then it returned, only to kill them quickly, since their immune system was gone. RIP: Aunt Marty, Steele, Carmen.

  • @finlandjourney6065

    @finlandjourney6065

    3 жыл бұрын

    @@lorinagosso While that is the norm, there are a few exceptions. Perhaps her young age aided her recovery. Then again they say 25% of cancers get cured all by itself (not sure if it applies to leukemia though), but I guess most don't wanna play with those odds and go for the chemo route, despite it perhaps only buying them more time and only making their early death even more likely.

  • @KhadaJhin04

    @KhadaJhin04

    3 жыл бұрын

    @@lorinagosso leukemia in a certain group age and the type of leukemia the person has determines the rates of their survival. Simply put the older you are the deadlier it gets, children have higher survival rates and longer remission. Sorry for your loss though, seeing a loved one succumb to illness makes you feel hopeless and it's a wound that never heals even after they pass.

  • @hanasarver3837

    @hanasarver3837

    3 жыл бұрын

    I’m so happy for you and Sarah. I hope she loves a long successful life!

  • @rachelvillarim3279

    @rachelvillarim3279

    3 жыл бұрын

    Hi Michael the world also won a precious gift then : Sarah. Please send her a hug all the way from Brasil !! She isa brave and inspiring girl ❤️🙏🏻

  • @m3m3d_
    @m3m3d_5 жыл бұрын

    That one guy just sitting there on the bed was horrified. I feel terrible knowing the mass pain they were going through.

  • @scarlettellison3090

    @scarlettellison3090

    5 жыл бұрын

    m3m3d_ I felt real sorry for him . He was just siting there and every one else was reacting to it. He was probably thinking that he was going to get it soon

  • @mariekekito3998

    @mariekekito3998

    5 жыл бұрын

    I would feel guilty for Being tho One Who got the placebo

  • @tryblight

    @tryblight

    5 жыл бұрын

    crumch

  • @soiboi1564

    @soiboi1564

    5 жыл бұрын

    Are you him (Looking at your profile pic even though I know it's just Arin

  • @jeaniejbutler4911

    @jeaniejbutler4911

    4 жыл бұрын

    the 2 (one in each room) who got the placebo will definately have long term mental issues from what they saw and heard..I hope they both got some great counseling...crap like that can mess your head up for life.

  • @nathanh2917
    @nathanh29178 ай бұрын

    I was one of the early people treated with skin grafts. I had 3rd and 2nd degree burns when i was little. Now I have no scars. I appreciate the human test subjects for what they have helped achieve.

  • @levendlicht
    @levendlicht3 ай бұрын

    Well, this happens to millions of animals all around the world every moment, and on the off chance they do survive after all the suffering, they are disposed off anyway...

  • @pilarlastname8053
    @pilarlastname80535 жыл бұрын

    KZread, I don’t think an add for a drug trial study is the best thing to run during this video. Like seriously, I don’t think people will want to take part in a study after watching this.

  • @MsLouisVee

    @MsLouisVee

    5 жыл бұрын

    Pilar Tromacek 😂😂😂😂😂

  • @skeeter7932

    @skeeter7932

    5 жыл бұрын

    2 months later and I got the add too!

  • @maibster

    @maibster

    5 жыл бұрын

    ye THIS TOTALLY HAPPENED...

  • @netook8

    @netook8

    5 жыл бұрын

    Yea KZread has no humanity or morality left. Google is probably run by Skynet

  • @petavirus5558

    @petavirus5558

    5 жыл бұрын

    XD still gonna, because someone got to be the one to do it

  • @gracelinenfelser8663
    @gracelinenfelser86634 жыл бұрын

    patients: puking, fainting, screaming in pain doctors: *Don't stop administrating the drug*

  • @JacyTheAngel

    @JacyTheAngel

    4 жыл бұрын

    Mhm

  • @Hazel4love

    @Hazel4love

    4 жыл бұрын

    😥

  • @jasonwishere3121

    @jasonwishere3121

    4 жыл бұрын

    doctors: its working its working..infuse more drug

  • @simonbarr9476

    @simonbarr9476

    4 жыл бұрын

    Ahhhh, the benefits of knowing more in the name of science

  • @whendis.roberts6817

    @whendis.roberts6817

    4 жыл бұрын

    Ya what's that?

  • @treeyellow4627
    @treeyellow46278 ай бұрын

    Safety standards was seriously lacking. Immediate stop after the first reaction. Every patient should have started in ICU wirh more Doctors present.

  • @KyleMatt11
    @KyleMatt118 ай бұрын

    I don’t know how a doctor can ethically and morally conduct a drug trial. The Hippocratic oath states “first do no harm.” Injecting a perfectly healthy human with an unknown substance seems the epitome of doing harm.

  • @hopesprings4155

    @hopesprings4155

    7 ай бұрын

    Do you have a better way to test new drugs?

  • @miepmaster25
    @miepmaster254 жыл бұрын

    an hour long, slow-pace documentary, totally for free on youtube! this makes me very happy

  • @ellenorbjornsdottir1166

    @ellenorbjornsdottir1166

    4 жыл бұрын

    Yus

  • @Neishianadiaaa

    @Neishianadiaaa

    4 жыл бұрын

    ᴴᵃᶰˢ ᴮˡᵃᵃᵘʷ me tooo

  • @jamie-leighgibson2338

    @jamie-leighgibson2338

    4 жыл бұрын

    There is hundreds of them on here they r amazing

  • @Grimy_Aaronarr

    @Grimy_Aaronarr

    4 жыл бұрын

    What KZread was really made for

  • @jaydensmith920
    @jaydensmith9204 жыл бұрын

    This is like watching a horror movie but every detail actually happened

  • @LiterallyEly

    @LiterallyEly

    3 жыл бұрын

    Ikr, it makes it WAYYY scarier... obviously

  • @SolarBlyze

    @SolarBlyze

    3 жыл бұрын

    @@LiterallyEly honestly this scared me more than any horror movie ever has

  • @c.w.6644
    @c.w.66448 ай бұрын

    as beeing a doctor myself, i can only congratulate to the doctor on charge how well he manged the situation!! congrats!!! ashes on my head. i couldn't have managed it better. dr from switzerland

  • @IrishElf
    @IrishElf8 ай бұрын

    I am a New Zealander, struck me, as in saying that someone from my small country got affected by this. Also, this is absolutely horrific, stomach turning.

  • @markhurter8668
    @markhurter86685 жыл бұрын

    If you don't want ads, skip to the end and replay it will make the ads go away. You can thank me later.

  • @sarina2364

    @sarina2364

    5 жыл бұрын

    YOU ARE A GOD

  • @NathanVdV

    @NathanVdV

    5 жыл бұрын

    @@sarina2364 or install an addblocker, no adds anywhere!

  • @sarina2364

    @sarina2364

    5 жыл бұрын

    You right, I gotta get on that. Thanks!

  • @davidmyles9967

    @davidmyles9967

    5 жыл бұрын

    thanks.

  • @moonshiner3223

    @moonshiner3223

    5 жыл бұрын

    A prophet like you comes along every 200 years or so. Thank you for this gift. The gift of this knowledge.

  • @DriftScale
    @DriftScale5 жыл бұрын

    Compared to an American documentary, I see a British documentary takes itself a million times more serious

  • @russelldingle4096

    @russelldingle4096

    5 жыл бұрын

    Of course. Tut. We don't do cartoons here mate

  • @ajakuk1

    @ajakuk1

    5 жыл бұрын

    I agree Mr dingle . You see Mr scale we always take this sort of stuff seriously. Did you see the world cup?😉

  • @secondswell

    @secondswell

    5 жыл бұрын

    @@russelldingle4096 ho ho cheerio and a spot of tea dingle berry.

  • @bustergibbons6573

    @bustergibbons6573

    5 жыл бұрын

    THAT IS THE BRITISH WAY - THEY LIKE THE STOIC APPROACH VS THE FEEL GOOD APPROACH BY AMERICANS. THIS SHOULD HAVE BEEN STOPPED AS SOON AS THEY HAD THE FIRST BAD REACTION. MONEY KEPT THEM FROM STOPPING IT

  • @mizzyuk8697

    @mizzyuk8697

    5 жыл бұрын

    Americans don't take nothing seriously.

  • @randallsmerna384
    @randallsmerna3843 ай бұрын

    Kinda strange that they didn't immediately put them on dialysis...

  • @louisenaude4467
    @louisenaude4467 Жыл бұрын

    I'm sorry for what these men went through, but I am also grateful for them, they made it safer for those that were brave enough to come after them to also take part in clinical trials

  • @HisameArtwork

    @HisameArtwork

    Жыл бұрын

    I found it interesting that they didn't accept women because it was considered too risky. While I can appreciate the chivalry it does aparently lead to mis-dosing for women because they don't test stuff enough on women.

  • @NotSoSerious69420

    @NotSoSerious69420

    Жыл бұрын

    @@HisameArtwork it’s also an immune system stimulating drug isn’t it? Women have stronger immune systems in some senses then men so it’s more risky to do first in human testing on women. Don’t think they often worry about it once it passes first in humans as it often moves to treating the people with the actual diseases soon after and someone with cancer is probably not as worried about side effects if it saves them.

  • @childofcascadia

    @childofcascadia

    7 ай бұрын

    @HisameArtwork Its because "average" is considered an around 160 lb 5'11 male to drug companies at the time this study took place. Its better now, people of different genders, sizes and genetic backgrounds take part.

  • @pixl2524
    @pixl25242 жыл бұрын

    David: literally dying The doctor: yooo what's good david

  • @apseudonym

    @apseudonym

    2 жыл бұрын

    😂😂😂 truly

  • @djangofreeman3153

    @djangofreeman3153

    2 жыл бұрын

    i laughed too loudly at this

  • @nancyhoward7005

    @nancyhoward7005

    2 жыл бұрын

    What is organ failer

  • @nancyhoward7005

    @nancyhoward7005

    2 жыл бұрын

    My husband's face swell up like this...allergic reaction to dye in hair color

  • @nancyhoward7005

    @nancyhoward7005

    2 жыл бұрын

    For all yall who do this kind of testing. Thankyou so so much. With out the test ....wow....

  • @DanaAshlie
    @DanaAshlie3 жыл бұрын

    Best re-inactments I've ever seen. Usually SOOO cheezy

  • @darasagan7479

    @darasagan7479

    3 жыл бұрын

    Dana Ashlie British do it better

  • @ItssMitch

    @ItssMitch

    3 жыл бұрын

    @natalie L Same but that's mostly because I am British.

  • @julieannjunemadrigal5034

    @julieannjunemadrigal5034

    3 жыл бұрын

    Dana Ashlie i agree plus the faces are quite identical too. i didnt realized it was just reenactment for the first 10 mins lol

  • @jissellelopez9978

    @jissellelopez9978

    3 жыл бұрын

    I honestly though it was actual footage

  • @jimmyjimjim4879

    @jimmyjimjim4879

    3 жыл бұрын

    So true !

  • @MoosesValley
    @MoosesValley7 ай бұрын

    Absolutely terrifying ... these 6 men were on the brink of death. 3+ years of recovery for 5 of them. Poor Ryan will never fully recover, his finger tips fell off, and he lost toes and part of his foot.

  • @clairepapadatos1116
    @clairepapadatos11169 ай бұрын

    Why would you inject a perfectly healthy person instead of asking Cancer patients to agree to the trial? Totally bonkers! 😢

  • @Vanereall
    @Vanereall3 жыл бұрын

    It's crazy to think that they didn't have an emergency protocol in place. That doctor was scrambling to find any other doctor.

  • @seanshields86

    @seanshields86

    2 жыл бұрын

    That dr was probably just a pawn on a larger chess board.

  • @billmartins5545

    @billmartins5545

    2 жыл бұрын

    You can't plan for unexpected reactions

  • @donaldprice9230

    @donaldprice9230

    2 жыл бұрын

    Very poorly administered trial for sure. Why inject them all at once??? Pathetic!!!

  • @Abdi-libaax

    @Abdi-libaax

    2 жыл бұрын

    @@nasramohamed no he called for the other doctors because he didn't know what to do.

  • @cataniamommaitalia87

    @cataniamommaitalia87

    Жыл бұрын

    They don't know what to be prepared for, that's why they're called drug trials. Unfortunately, too many people are still willing to inject untested drugs into their bodies with pharmaceutical companies having immunity from all outcomes

  • @danavenzor1169
    @danavenzor11692 жыл бұрын

    The 2 receivers of the placebo are in my opinion entitled to damages as well, as are the staff who all were undoubtedly traumatized by witnessing this dreadful horror.

  • @SaraWOanH

    @SaraWOanH

    2 жыл бұрын

    You do know they willing signed up for this, knowing that there could potentially be a risk of death right?

  • @jjjjdooley

    @jjjjdooley

    2 жыл бұрын

    Nope

  • @andreabobbette825

    @andreabobbette825

    2 жыл бұрын

    Agreed.

  • @andreabobbette825

    @andreabobbette825

    2 жыл бұрын

    @@SaraWOanH Where does it say in the contract "risk of death"? Do you work in this field?. They would never get people by stating that fact. They Will Say it may cause side effects (like organ failure) but not death. I do see what you are saying but they picked strong healthy young men. Emphasizing death is not a priority. Also... I would never do it. My friend fell fast after being talked into a trial cancer drug by her doctor friend....sad scary and I'm not built for it. My nerves and worry are too bad...😆

  • @thebikehub7421

    @thebikehub7421

    2 жыл бұрын

    Sounds like an inside job done by a lone crazy scientist.

  • @Kelli-br5px
    @Kelli-br5px8 ай бұрын

    Truly appreciate learning from this documentary more about drug trials and the way it was presented. Real Stories is certainly a favorite production company of mine when it comes to documentary filmmaking❤

  • @teddy2596
    @teddy259610 ай бұрын

    Thank you for posting ❤

  • @colesmith7509
    @colesmith75093 жыл бұрын

    The poor nurses. They couldn't have imagined this was possible, and they definitely felt partly responsible.

  • @finlandjourney6065

    @finlandjourney6065

    3 жыл бұрын

    The old nurses knew. They've seen all sort of things. That's why they tend not last too long in the profession, and thus are all the time replaced by younger better indoctrinated by big pharma teachers ones.

  • @nic00001

    @nic00001

    3 жыл бұрын

    @@finlandjourney6065 oh the lunacy

  • @ross1116

    @ross1116

    3 жыл бұрын

    They were in part responsible. They rushed the injections from how it was explained. The first man was showing bad reactions before the last couple were even injected.

  • @colesmith7509

    @colesmith7509

    3 жыл бұрын

    @@ross1116 I think it was the protocol they were forced to follow. I agree that they definitely should've stopped though

  • @meganbretbrunner2344

    @meganbretbrunner2344

    3 жыл бұрын

    It is a nurse's responsibility to advocate for their patient, they can in fact, intercept prescriptions, and refuse orders as long as it's in the best interest of the patient.

  • @Noodles03
    @Noodles035 жыл бұрын

    I cant imagine being one of the people with the placebo... just watching and listening to everythung around you, always wondering if youre next and when its going to happen. It sounds so terrifying...

  • @trinitylivingston1286

    @trinitylivingston1286

    5 жыл бұрын

    Yeah and he was so young at the time so it really pulls at your heart for the poor boy.

  • @onistgaming5177

    @onistgaming5177

    5 жыл бұрын

    American roulette

  • @alex73217

    @alex73217

    5 жыл бұрын

    @Addicted 2This but also guilty though. Survivors guilt

  • @etherraichu

    @etherraichu

    5 жыл бұрын

    Nah. after they were the onlyone in the room it didn't happen to, Im guessing they figured out they had the placebo. But the first hour or so would've been rough, yea.

  • @edelleaa

    @edelleaa

    5 жыл бұрын

    I would feel so very guilty honestly

  • @birdyelke775
    @birdyelke775 Жыл бұрын

    Am baffled of what I'm hearing. Easy money, trusting the government, yet you're almost lost your life, and most of you are not uneducated people. Wow 🥺🥺🥺🥺

  • @janicemackie611
    @janicemackie611 Жыл бұрын

    You are a true inspiration to all….we tend to complain about a lot of petty things but your story truly awakens the senses to what’s important….so happy you got through it with the help of your wonderful family.

  • @email2336
    @email23364 жыл бұрын

    In the U.S the hospital would of have tried to charge you for your stay

  • @dr224

    @dr224

    4 жыл бұрын

    Facts.

  • @Thinkingisallowed

    @Thinkingisallowed

    4 жыл бұрын

    You are right, and they would have charged 3,000 a night.

  • @duck3819

    @duck3819

    4 жыл бұрын

    You just nearly died because of us... Give us $30,000

  • @justjadethings9630

    @justjadethings9630

    4 жыл бұрын

    @@duck3819 That is very accurate. My quack of an orthopedist gave me an unnecessary MRI, over my ankle being swollen and having pronation. It found bone bruising, JUST BONE BRUISING. It was a waste of 2hrs and $900

  • @aprilminder6851

    @aprilminder6851

    4 жыл бұрын

    donte ray damn right they would have