Your videos on chronic fatigue are simply amazing, doctors like you give me faith in the medical system. I was passed around so many different doctors for many years who didn't believe me because all my blood tests and other medical examinations were within the "normal range". I finally found a doctor who listens to me and does his very best to improve my quality of life, but I know many people are not so lucky and have lost hope. Thank you educating more people on this subject, I hope there will be more research done into this condition by the medical community.

@PsychiatrySimplified

Жыл бұрын

Thank you for your feedback. 🙏🏼. It is definitely a misunderstood condition but more so because of the current silos in medicine. It's a condition that requires many heads to come together for the patient.

@Truerealism747

Жыл бұрын

Do you have.pain constant with your cfs

@roxanne1092

Жыл бұрын

My blood work comes out good too. I have a great doctor now. I had one for 20 years and after many fails trying to help me, he just kinda threw pills at me and that was that.😢

@Truerealism747

Жыл бұрын

@@roxanne1092 are you hypermobile

@roxanne1092

Жыл бұрын

@@Truerealism747 I am a little. But not enough for my doctor to diagnose me.

This is the most unbelievably valuable comprehensive explanation of how these all connect and what we who are ill with these conditions might do strategically. I can't thank you enough for your efforts and brilliance bringing this into the light.

@PsychiatrySimplified

11 күн бұрын

Thanks for your feedback

Great to see a medical specialist who genuinely understands the ANS dysfunction in ME/CFS 😊 Too bad I'm on the other side of Melbourne & your practice is too far away for me to travel. (Too much time upright!)

This is the most cohesive discussion I have seen, and thoughtfully organized. Your recaps anticipated my thoughts and questions. A second time through and I will potentially be able to explain the role of the CNS to the periphery to my mecfs ill husband. His scientific brain is still razor sharp, so I have to be on my best game! Best outcome is that he comes away with new ideas for his doctor. Thank you!

@PsychiatrySimplified

10 ай бұрын

Thank you for your feedback. I really appreciate it 🙏🏼

Thank you so much for continuing to address CFS.

@PsychiatrySimplified

Жыл бұрын

Our pleasure!

@leftthatbehind6090

11 ай бұрын

@@PsychiatrySimplified yes thank you so much 😭🙏🏻 it means a lot

Thanks so much for your fascinating discussions on ME/CFS. A very helpful and thoughtful resource. Thank you for taking such a close interest in this poorly understood condition. As a sufferer, please may I give some feedback for the production of future videos? One of my symptoms is that I have great difficulty cutting out background noises, so I really struggle listening to this video due to the background soundtrack. (I also find the ‘urgency’ of the background music further activates my SNS.) I’d much sooner just have your voice to listen to. I realise these issues may not be something that would occur to someone who does not have the illness, so hope you don’t mind me making you aware. All the very best, and good wishes for 2024.

@PsychiatrySimplified

6 ай бұрын

Thank you . I really appreciate your valuable feedback.

@Isckry

2 ай бұрын

Have you tried just to activate the close caption option? By the way, sometimes he speaks so fast, it is so difficult to follow the narrative regarding so many observations and studies. Trust me when I tell you, I took the time to pause, go back, listen to it again, reading the captions.... OMG thans for this amazing and professional presentation!

Wow, so much information packed into this video. Very interesting the biological connections of ADHD and CFS. I’ve had gradual onset CFS that really became obvious 4 years ago. Then it became more complicated by adding long covid. And I’ve recently been diagnosed with ADHD that’s been there my whole life. I’m in my 50s.

@PsychiatrySimplified

17 күн бұрын

Glad you found it useful. Thanks for sharing and as you show it’s very interconnected

Superb summary of a complex issue JParker MD

What's crazy, is I was mis diagnosed for anxiety for like 30 years.... till my psychiatrist dx me with Adhd. which my whole life makes sense. When I started having really weird symptoms.... I went back to him. We figured maybe tolerance... to meds... but it coincided with my Covid dx. I went back a year later.... and brought up long haulers.... and he spoke exactly like you did, which I actually was suspecting as well. I work in diagnostic imaging, so im sorta invested in it, as well as see it. For me the spike proteins I think are blowing up my app/mitochondrial processes.... so im starting there. Upped Adhd meds... it's not perfect, as a year ago I could bike about 35 miles, and if I bike 4 now.... im spent for 3 days... this is a crazy rollercoaster... I just feel bad for those with executive dysfunction.... with no prior tools to help.

@PsychiatrySimplified

Жыл бұрын

Hope you get the help. Seems like you are on track! Wish you well.

This is absolutely amazing.

@PsychiatrySimplified

7 ай бұрын

Thank you 🙏🏻

Thank you for doing these videos❤ I have CFS and FMS. It’s so hard to wake up and live. I am having insomnia really bad lately. I was given Amitriptyline and it helps with falling asleep. So now I’m extra tired and wake up from pain still. The medicine makes me even more sleepy when I’m already exhausted 24/7.

@PsychiatrySimplified

Жыл бұрын

Sorry to hear. Hope you can see a physician to help target the range of issues - pain, fatigue & sleep. In the video I've mentioned evidence based treatments for this. Hopefully you can discuss this with your doctor. Wish you well

@alexam5336

11 ай бұрын

Same! 😢

@gillsmith3723

6 ай бұрын

Thanks so much for your fascinating discussions on ME/CFS. A very helpful and thoughtful resource. Thank you for taking such a close interest in this poorly understood condition. As a sufferer, please may I give some feedback for the production of future videos? One of my symptoms is that I have great difficulty cutting out background noises, so I really struggle listening to this video due to the background soundtrack. (I also find the ‘urgency’ of the background music further activates my SNS.) I’d much sooner just have your voice to listen to. I realise these issues may not be something that would occur to someone who does not have the illness, so hope you don’t mind me making you aware. All the very best, and good wishes for 2024.

How do you know if Mast cell causing you to crash from everything you put in your body or if it’s just your body stuck in a state of hyper arousal mixed with a state of fatigue? I saw a specialist and my result was negative but I’ve been told that is very hard to catch. Any insight is appreciated because I’ve been crashing from every medicine and every food for 3 1/2 years and I am completely debilitated now.

I was among the early group of individuals diagnosed 40 years ago because I was fortunate to have a psychiatrist dad who worked at a teaching hospital. My father spoke to fellow doctors and heads of their department until a diagnosis was found.

@PsychiatrySimplified

3 ай бұрын

Thanks for sharing. Really lucky to have had that. But also shows how difficult it may be for others to get the diagnosis.

@kathleenkelley7701

3 ай бұрын

What 40 years of recovery and relapse has taught me is when you find a doctor who gets it you are lucky and as Michael J. Fox pointed out doctors need to remember the disease sufferer has first hand expertise.

Heya Dr Rege This was an awesome vid! I'm on my first placement ever right now and it's a psych ward lol. I wonder what my reg and consultants would think of this vid. Neuropsychiatry is such an interesting field!!! As someone w/ fibro I also feel like understandings towards functional disorder pathophys can be so poorly understood by patients and clinicians alike. Me too, to be frank. I'd say this vid taught me heaps!!! so thanks a lot :)

@PsychiatrySimplified

Жыл бұрын

Please share this with them. 😀. Really appreciate the feedback. It's also the reason why we created a webinar series addressing these conditions. We as neuropsychiatrists can do a lot! Thanks once again.

Amazing, thank you so so much, so much knowledge that I sent the l8nk to my family Dr to be able to help me better with my symptoms. I am suffering from Anhedhonia, depression, PTSD, and ME/CFS thats becoming much worse now, after many years.

@PsychiatrySimplified

17 күн бұрын

Sorry to hear. Please have a listen to other videos as I outline some potential principles for treatment

Thanks for covering this. Thanks for listening to the comments.

@PsychiatrySimplified

3 ай бұрын

Any time!

Fantastic information. Keep doing what you're doing 💯 You perfectly describe and explain my medical issues.

@PsychiatrySimplified

5 ай бұрын

This weekend we will release another one on Long COVID. Hope you can get the help you need

@subjectively-observered

5 ай бұрын

@@PsychiatrySimplified Are you able to do a consultation?

@PsychiatrySimplified

5 ай бұрын

Sorry can’t due to medicolegal reasons

How does this cause heat intolerance and how do I combat it? Since long Covid it is crippling.

😱 I’m diagnosed with ADHD and ME/CFS. It sounds like a contradicting diagnoses. Thank you for this !

@PsychiatrySimplified

5 ай бұрын

Very common comorbid presentation. Also covers this in the latest video on decoding long COVID

This is fascinating. Is there a transcript of this video? I ask because I am not a medical professional but am struggling through many of the symptoms you're describing here. I would love to learn more about the condition I'm experiencing

@PsychiatrySimplified

Жыл бұрын

Transcript on KZread. Click on transcript.

My neurologist’s medical assistant told me she will not see me for chronic fatigue. What a slap in my face. I’m also tapering from klonopin the past three years of my chronic fatigue. She won’t see me as I taper.

This is actually a good video. Thanks for sharing. The brain and spine are a big part of ME/CFS. I wonder if OP knows about Jen Brea's story?

@PsychiatrySimplified

6 ай бұрын

I read it after you mentioned it . Thanks for sharing.

It's thought that the brainstem also plays a central role in ME/CFS with POTS

@PsychiatrySimplified

11 ай бұрын

Yes thats what i was highlighting in the video - that while peripheral autonomic nervous system responses are looked at the role of Amygdala , PAG in activating brain stem centres is crucial in Management

How is it that a psychiatrist knows more about these conditions than neurologists?

@ey67

4 ай бұрын

Because he's done the work that needs to be done. Brilliant educator. Not a corporate toad. Refreshing and he's easy to follow. Excellent presentation.

@davidkruse4030

4 ай бұрын

They are both supposed to be neurologists. It’s the same system

@PsychiatrySimplified

3 ай бұрын

Thank you for the feedback. Henry Miller Neurologist said Psychiatry is neurology without physical signs and needs diagnostic virtuosity of the highest order.

Can you do a vid on the effects of benzo BIND and connection to ME/CFS?

This is all such amazing information but how do you find a doctor, a team, or group that works together like this?? I have all the above symptoms and have been laying down for almost ten years. I was diagnosed with fibromyalgia and sent on my way. I’m just now researching and learning about all my symptoms and stumbled upon your channel. I’m in California and don’t know where to find a doctor that treats all this. I have a psychiatrist but he doesn’t treat the whole body.

@PsychiatrySimplified

9 күн бұрын

Yes the MDT framework implementation is an issue and one of the biggest challenges.

I came here expecting to find something speculative, but found this highly fascinating and research-based video - thank you for this! After decades of exploring so many theories and medications I am 100% certain the two aspects you have mentioned - clonidine type meds and enhancing dopamine transduction are exactly the prominent issue.

@PsychiatrySimplified

6 ай бұрын

Thanks for the feedback. 🙏🏼

@wetelectronics238

6 ай бұрын

Im presuming many psychiatrists may not be aware of some of these central aspects of these conditions. Is there a particular psychiatrist you might recommend in Melbourne that might have some experience with treating the central aspects of these disorders? @@PsychiatrySimplified

@wetelectronics238

6 ай бұрын

Looking online most Neuropsychiatrists in Melbourne seem to fit CFS in the Functional Disorder category which is frustrating. Id love to know who you might recommend as a neuropsychiatrist that has experiencing managing these kinds of disorders in a general sense. thank you

@PsychiatrySimplified

6 ай бұрын

Difficult to say as with these conditions it’s really a formulation and the way I see it is that psychiatrists should be able to integrate the elements to target symptoms. Many medications that we use are very effective in these conditions

I am a general psychiatric provider. I see so much of this and am trying to build my knowledge. I have many questions. 1. Can anything be done for the autoimmune component of many of these disorders? 2. You mentioned ADHD as a risk factor. The risk factor I most see is complex PTSD. What do you think? 3. We use a lot of antipsychotics in psychiatry. Could patients have these types of side effects from the dopamine blockade? 4. My patients are afraid to take BP meds due to a fear of worsening symptoms: could that occur? 5. Both beta blockers and clonidine have an uncommon depression risk: have you seen it? 6. I am intrigued about the use of stimulants aside from the stimulant shortages. Do you start with SNRI, bupropion first then do modafinil, and lastly stimulants for your non ADHD patients? Thank you very much!!!

@PsychiatrySimplified

Жыл бұрын

Thanks for the questions. It's impossible to do it justice via YT. 1. Dopamine and inflammation are related. Many ADs are anti inflammatory. Also seen in clinical practice. 2. Complex PTSD & ADHD overlap - we covered this in our academy 7.5 hr ADHD Webinar series. 3. Higher doses can 4. Clonidine can stabilise Sx in POTS when appropriately used. If interested I would recommend having a look at the comprehensive courses - neuropsychiatry of CFS & LC - on demand to be released soon - we use case studies which will answer questions with evidence. There is a lot we can do. www.academy.psychscene.com/events/the-neuropsychiatry-of-chronic-fatigue-syndrome-and-long-covid/ 2. ADHD webinar series we have cases that cover CPTSD / CFS well. They are both 7.5 hrs just highlighting the amount of material - www.academy.psychscene.com/courses/the-adhd-masterclass-series-the-ultimate-guide/

@laurainthesky3765

Жыл бұрын

@@PsychiatrySimplified I appreciate your time! I am US based. Do your courses offer CME? Also do not forget about your nurse practitioner colleagues 😁. So few MD resources mention us as part of the team.

@PsychiatrySimplified

Жыл бұрын

@@laurainthesky3765they have self accreditation. We do not separately accredit them with US bodies as due to time and cost they take away from development of courses. We hope individuals see the value as part of educational development. they are accredited by the Australian bodies and after completion one receives a certificate in their portal ( CPD portal is part of this annual subscription) . Inherestingly we have US based NPs as members 😀. We value NPs highly and I work closely with them.

@angli524

10 ай бұрын

What do you think of Pulsetto or Gammacore? I find that helpful for some of my pts. I'm neuro and sleep trained and my sleep fellowship was mainly psychiatrist focused.

….also, what do you think about LDN, low dose naltrexone? I’ve been researching that and it’s fascinating. It sounds like it has really helped a lot of people but it’s not talked about. My doctors don’t even know what it is. They just hear “naltrexone “ and that’s all they know. They haven’t heard of the low dose and its amazing benefits. Thx so much for all your info!

@PsychiatrySimplified

9 күн бұрын

There is evidence for LDN. Benefits are present at the lower end of the spectrum - at the mod - severe end it can be associated with side effects for some, for others it provides benefits and then there is breakthrough. So it often works well as part of an overall multi-pronged regime.

Could you give clues into telling if you’re having fatigue or if you’re feeling overstimulated? It’s so hard to tell the difference sometimes because everything is so mixed together. Also could you give an example of an NA and a DA drug? You mentioned is for the fatigue and lack of concentration. Can you explain what you mean by poor concentration? I do not just get brain fog I feel like my entire brain is splitting apart into pieces the only thing that is ever brought it back Sam is out of them. I’m not sure what I need. I am working with a psychiatrist but he doesn’t know either because I keep crashing from all the medicine. Thank you

I have pots and autonomic dysfunction and chronic pain and migraines etc. I feel like utter shit. I am always in pain and short of breath. I took mucuna pruriens supplement trying to raise dopamine and felt even worse like I was going crazy and dying.. Something bad runs in my family, others have pots, some have MS, my brother has schizophrenia... Etc

@PsychiatrySimplified

7 ай бұрын

Listen to the part where I talk about hyperarousal. Increasing levels of excitatory and activating neurotransmitters without addressing hyperarousal can result in side effects often heightened anxiety, arousal etc. thus addressing hyperarousal is key .

I did a very specific advanced autonomic test that showed I had excessive parasympathetic and sympathetic excess . Diagnose chronic fatigue syndrome and pus. I am in severe distress 24 seven because I’m crashing from every medicine that I take so I can’t get my system calm down. Do you have any recommendations not medical advice just discussion? What parts of the brain need to be modulated to modulate both sides of the autonomic system? The only thing that has ever helped me is out of them but I crash first from it so I cannot get calm down

I have hEDS, mast cell CFSME , POTs etc …..long long list. I’m void of the CYP2D6 allele. Non functional….I can’t seem to be heard about. I’m given meds I can’t metabolize and I was on SSRI for over 10 to 20 years that I never could have process.. how to heal from medication toxic effects ?

TY for such a highly comprehensive explanation!. You spoke of a genetic mutation in a NE transporter. Can you point me to further info? ME/CFS and assoc. conditions runs in my family and I'd like to look into genetic testing

@PsychiatrySimplified

10 ай бұрын

Here is a reference. The genetic testing capability varies. www.tandfonline.com/doi/full/10.1080/14017431.2017.1355068

Do you have a checklist or format to share with my physician to help guide accessing and treatments for MECFS? As the PCP is the gateway to specialist services, it would still seem useful to have a few things worked out sooner than later to reduce struggling with disability. This is a problem with the silo effect in healthcare. So glad you are willing to step out of your lane and bring it together.

@PsychiatrySimplified

10 ай бұрын

There isn’t a format or checklist. Because it’s so individualised. I’ve published articles which may help. This is ok LC - has pathophysiology and Treatments with clinical insights psychscenehub.com/psychinsights/long-covid/ There are articles on CFS and fibromyalgia as well. Later this year we will have a 7.5 hr course on CFS / Fibro / LC - on academy.psychscene.com to increase the understanding of this condition. Wish you well with the treatment

@shawnaford5540

10 ай бұрын

@@PsychiatrySimplified Thank you. I will look at and share your link to my physician and hope that I will be looked at differently. As I had become her patient with a previous diagnosis of treatment resistant depression and my fatigue was always called depression. From 2008 to 2022 until my new psychiatrist in the Mood disorder program actually listened and diagnosed MECFS. And the psychologist diagnosed Autism. It can be difficult to not be seen as “only” a “head” case. A silo effect. And as from 2008 to 2022 my fatigue was only treated as depression. Yet recently I did find a KZread video by an OT that I shared with my OT that did help me get more customized appointments or helpful appointments. Autism with MECFS was not her standard patient. My OT is part of my team in the mood disorder clinic, unfortunately they do not have the mandate to deal with MECFS. Your work here and your answer emphasizes the complexity of mind body awareness. Thanks for your videos. I do hope to find some more tools to manage.

I can literally barely breathe I’m like suffocating all the time. Would you recommend could help that? What is that a sign of hyperactivity or the opposite

Can you please tell me what to do when every medicine you put in your body crashes you you feel like you’re trapped within yourself like you are drowning within yourself I don’t know how else to explain it you can’t focus your brain is out of control and you feel like you were literally sunk inside of a hole. Can you please shed any light on that I don’t know what to do because any medicine I put in me makes it me crash. How do you decipher what medication you need to break the cycle? I’m currently on Ativan which does helps him but it crashes me first.

Any information in ldn.ime in ldn but not helping with pain but ibs

You have nailed it! Can I hire you as my Dr?

@PsychiatrySimplified

Жыл бұрын

Thank you for your feedback. 🙏🏼. Not sure if the other comment was serious but unfortunately due to medicolegal reasons we have to stick to education only. Wish you well

You are a tremendous resource. How do we get in touch with you.

Are there medical tests to rule out neuro inflammation, so we can get to the root cause? I had gotten Anhedonia and all these other symptoms. It ruined my life but I got better over a year, my Anhedonia lessen or doesn’t feel like I have it but I still have two remaining symptoms. I’m upset about it now that I want to know what happened. Seems like meds don’t really work, sleep aids, supplements, and Ketamine based on my experience. Thanks for your solid information.

@PsychiatrySimplified

Жыл бұрын

Many will be in research settings but this article has the tests on ME / CFS - for long Covid we also have an article with a list - see here 👉psychscenehub.com/psychinsights/chronic-fatigue-syndrome-myalgic-encephalomyelitis/

@mariosegura4864

Жыл бұрын

Thanks for you response

This might sound crazy, but would cayenne pepper in capsule form a few times a day help with the blood flow? I'm thinking of patients who can't tolerate allopathic medicine.

Hi! Could Guanfacine be better and more tolerated than Clonidine or Methyldopa?

@PsychiatrySimplified

Жыл бұрын

Depends on the symptoms being targeted. Clonidine and methyldopa are usually effective in reducing central hyper adrenergic states. Clonidine is non selective alpha 2A pre synaptic agonist this reduces NA levels overall. Guanfacine is alpha 2 A post synaptic - this tends to activate post synaptic alpha 2 A receptors which improves prefrontal cortex functioning - PFC has alpha 2A receptors. Here is some detail in this video we did. kzread.info/dash/bejne/hp2jr5uHqdDAiMY.html

How do you suggest we get more dopamine besides using antidepressants?

@PsychiatrySimplified

6 ай бұрын

Sunlight, exercise. Diet ( iron, vit b12, folate, Vit D) all essential in production of DA. Adequate sleep, reduction of ‘stressors’ are some. It's not just about getting dopamine but the regulation of dopamine to achieve homeostasis ( optimum functioning of body and brain) .

Yes I have Asperger's now diagnosed heds CFS fybromyalgia had pots TMS Dr told me it's my brain does it damage the brain though nerves what's worrying me

@Laughing-doves

Жыл бұрын

Don't worry - remain calm when you get symptoms - as the fear will make it worse.

Also do you know any psychiatrist in the United States that could work with us? Thank you I cannot find anyone here that is willing to or that it is knowledgeable to be able to make a difference to help. Or any other type of doctor that you know of in the US to help

I would like to go further. Mind you, I am not a specialized doctor in psychiatry; simply a physical therapist. However, in this video there has been mentioned certain medications to counter the complex dysregulation which occurs in patients which chronic fatigue; but it doesn't not include non-pharmaceutical treatment for chronic fatigue syndrome (or long covid, or chronic fatigue; whatever you may call it). One of the key aspects mentioned in this video has been about concrete evidence in correlation between the hyperadrenergic state and chronic fatigue, I would like to expand on this. It is commonly known that a hyperadrenergic state is in short, a exacerbatingly altered autonomic nervous system, specifically an excessively high sympathetic nervous system. Therefore and in perspective of non-pharmaceutical treatment, what would you recommend to patients that do not concede to taking all these drugs which have been mentioned, beta blockers, methylphenidate, alpha 1 agonists, etc? If the core problem of being in a hyperadrenergic state is fundamentally having an overactive sympathic nervous system, would it be incorrect or illusive to recommend habits which decrease the sympathetic nervous system and increase the parasympathetic nervous system? What I'm reffering to is that there is clear evidence that relaxation techniques increase the parasympathetic nervous system and decrease the sympathetic nervous system. Therefore, I would like to see in future investigations the inclusion of a holistic approach to patients which suffer from chronic fatigue, such as meditation, exercise (evidence suggests that chronic exercise attenutated heart frecuency, which according to this video and due to the bidireccional connection of the heart frecuency and the amigdala, should imply beneficial effects in the limbic system as well), breathing exercises, participating more in social interactions, and prioritizing things that make you feel good; should be also included as one of the central pillars for chronic fatigue syndrome. In short and strictly speaking of chronic fatigue in relation to a hyperadrenergic state, there should not only be an impementation of pharmaceuticals, but also empower, educate and give the patient the neccesary tools for he himself to practice habits which will enhance the parasympathetic nervous system (relaxation) and finally bring a halt of a very excited sympathetic nervous system. Thank you for the video and I hope you don't take my commentaries as any sort of disrespect (quite the contrary), this is only a very humble opinion from a humble physical therapist.

can you link studies saying the pathophysiology behind defective cardiovascular tissue perfusion in ME CSF is due to excess vasoconstriction? It is my understanding that it is due to excess vasodilation/impaired vasoconstriction?

@PsychiatrySimplified

10 ай бұрын

The associations of elevated levels of both alpha- and beta-AdR-AAB with more severe fatigue and muscle pain in post-infectious ME/CFS could point to overactivity of vasoconstrictive alpha-AdR-AAB or an impaired function of vasodilatative beta2-AdR-AAB. www.ncbi.nlm.nih.gov/pmc/articles/PMC8397061/ In ME/CFS, hypovolemia and a predominance of vasoconstrictor over vasodilator influences by β2AdR dysfunction and other pathomechanisms of endothelial dysfunction cause cerebral vasoconstriction. Autonomic dysfunction could also be involved by overshooting responses of the sympathetic nervous system (vasoconstrictor overshoot) and of respiration (hyperventilation) [38]. The resulting hypocapnia enhances vasoconstrictor cerebral vascular tone. www.ncbi.nlm.nih.gov/pmc/articles/PMC10224216/

@eddie8489

10 ай бұрын

@@PsychiatrySimplified I'm sorry but this is incorrect. Impaired vasoconstriction is what leads to orthostatic intolerance and POTS in people with ME/CFS. Just think about it, if you have proper or even excess vasoconstriction, your heart doesn't have to work harder to compensate, this isn't the case for people with excess vasodilation/impaired vasoconstriction. www.ncbi.nlm.nih.gov/pmc/articles/PMC7712289/

Thank you for the very amazing and informative video! However, I do suffer from ortostatic intolerance (Hyperadrenergic POTS) and SNRI did worsen my symptoms due to the same fact that NRI medications can increase sympathetic nervous system tone, which may increase heart rate (HR) and worsen symptoms in POTS. Why would you mentioned that SNRI would help someone with a hyperadrenergic state or a hypersensitive nervous system? You do not mention anything about just using pure SSRIs Thanks.

@PsychiatrySimplified

Жыл бұрын

The central hyperadrenergic state if present requires reduction of the hyperadrenergic state through use of medications such as alpha agonists discussed in the video. SNRI’s do not treat a hyperadrenergic state and may actually worsen it . However once the central hyperadrenergic state is reduced SNRIs can be used to target Sx such as pain or cognition etc. SSRIs are used to reduce amygdala activity only mildly - they are unlikely to address the higher end of spectrum. Moreover at higher doses they increase emotional blunting and in patients with brain fog that can sometimes be worsened .

@juvesaucedo

Жыл бұрын

@@PsychiatrySimplified thank you for the reply. I had long covid in Jan 2021 and recovered after 6 months after having a form of chronic fatigue (This is absolutely not medical advice for the readers to discuss always with your doctor) by using SSRI, valproate semisodium and antipsychotics. One year ago, I had some drug-induced trauma and tachycardia and ended up with POTS, OI, or ME/CFS they did a tilt test which showed POTS and a transcranial echo-doppler which showed hypoperfusion on my brain. It is still unclear. What is clear is that I had in the beginning of Post-exertional Malaise, I was in bed due to extremely low energy fatigue (it is mental, spiritual, and physical fatigue). I was given SSRI, which did not help. Months later, I was given Venlafaxine, and I took me from bed to the gym in just a couple of weeks; however, two months later when the Venlafaxine dose was increased due to minor anxiety issues, I developed High blood pressure, and relapse into Dysautonomia (POTS, OI, Chronic Fatigue). I was then given nebivolol (a beta-blocker) with pyridostigmine early this year, 2023. I tried to switch from venlafaxine to another SSRI, but it worsened my symptoms. I do see your point now that the Central Hyperadrenergic state shall be reduced and stabilized and then apply SNRI or any other dopamine reuptake inhibitor, as you explain very clearly in your video. Since I am dealing with a hypersensitive Nervous system or Dysautonomia, I will discuss the strategy (not that I am the expert but many of the doctors sometimes are not well aware of what is going on and other are really good) with my neurologist, cardiologist, and psychiatrist the use of alpha agonists if the Betablocker + Pyridostigmine are not effective and either keep the SNRI or switch to a Dopamine antagonist. Excellent information. Is Valproate (VPA) and its forms recommended in some cases of chronic fatigue or dysautonomia?

@PsychiatrySimplified

Жыл бұрын

@@juvesaucedo valproate being an agent which potentiates GABA is helpful in reducing arousal which can help central hyper adrenergic states like benzodiazepines do- however as always this depends on the level and severity. In the video ( it may take another listen to consolidate information but I discuss how dysautonomia and fatigue are linked. Management tends to be balancing hypoactivation & hyperactivation to put it simply to bring it to a balanced state . Best wishes .

So if we have CFS fybromyalgia have we got more chance Parkinson's later on so it needs to be addressed asap

@thegangov14

11 ай бұрын

Good question, also wondered about this.

Does Clonidine work on the brain the way Ativan does? Because Ativan is the only thing that has ever made me feel more normal for in a crash I feel like this is the type of medication I need to be looking for except for that I keep crashing when I take it. So I’m trying to try other routes. Period beta blocker just crash me did not help me at all. Under the circumstances do you think clonidine could help or do you think I need to be using other drugs that are affecting my brain in a way like Ativan does? I tried Abilify and I crashed and it made me feel awful like I didn’t even know who I was

@nancyburks5996

7 ай бұрын

Clonidine helps me much more with exacerbations. Beta blockers just exhaust me and make breathing for difficult.

@elizabethread6878

7 ай бұрын

@@nancyburks5996 Does it stop the crashing

Hi Dr. Rege. Can MAOIs help with mental fatigue? (Apparently, they used to be called “psychic energizers.” 🧠⚡💊)

@PsychiatrySimplified

Жыл бұрын

Good question. Any agents that increase DA & NA can address fatigue as long as the hyper arousal states are also addressed. We have the time stamp - where we discuss stimulants in CFS. While MAOIs can help there are other options as well. In CFS the tolerability aspects may limit their use.

@DennisBolanos

Жыл бұрын

@@PsychiatrySimplified Good to know, thanks!

so what can I do to help my CFS? im 10 yrs in and literally have no life or energy. can any drugs help?

@PsychiatrySimplified

6 ай бұрын

Yes medications help - a multidisciplinary approach is needed as its a heterogeneous condition and no one size fits all

@martinskoglov5128

5 ай бұрын

26:51 This is told in a medical english above my vocabulary skill’s, and then we haven’t even discussed the rapid speed you talk in! That out of the way, thanks for your lecture not easy to understand all of it, but it’s extremely interesting. I just have to ask a question because I’m not sure i understood all the parts of the dopamine effect. My question is this can you have fatigue, and almost always feel tiered, but you, can have energy to do things when the ADHD going for dopamine hunts. But even if you get spoons (spoon theory) to do things and feel good and energetic in the moment, but not loong time after the dopamine feast, can be a hour or some days. This is when the spoon bank’s employees comes knocking on the door and wants there spoons back, and with a high interest. And that day i can only hope i have enough spons for the intrest and the rest of the day or i and up “crashing” and doing nothing aka binge eating and doom scrolling on the phone. I have ADHD and Dyslexia, and my psychiatrist event want to make Kinder egg of everything by giving me OCD, it feels like get three buy one, happy time’s. Well So, for about a year from the end off 2000 to the end of 2001 i had the diagnosis “postviral fatigue syndrome” in my medical documentations, that changed over a night the day i got my ADHD medically documented. Oh my “short question” got carried a way i see, that’s aa unusually treat for someone with ADHD, i must be the first in the world right? 🤣🙈 Question: Can i actually be fatigue but because of my ADHD hunt for Dopamine and the Lexfetamine and the rest medication get the ADHD to trickster me i can’t be fatigue?

@PsychiatrySimplified

4 ай бұрын

In short, yes. Individuals with ADHD are more likely to have energy/motivation for things they derive pleasure / immediate gratification from.

Please Dr Rege, do you know if there's someone in Perth that can treat my CFS/ME? I've passed the 10-year mark well and truly and it's only getting worse despite my best efforts at intervention.

@PsychiatrySimplified

5 күн бұрын

Im sorry I don't know anyone specific. Ideally a MDT with specialists can make a difference. I would recommend discussing this with the GP who could decide on the main specialists that need to be involved.

@ksarge5773

5 күн бұрын

@@PsychiatrySimplified Thank you, I 'll do that.

@PsychiatrySimplified

Күн бұрын

Wish you well

@ksarge5773

Күн бұрын

@@PsychiatrySimplified not much luck with my new GP, but results from a cytokine panel recommended by my functional medicine nutritionist have produced some odd results that indicate this may be inflammation from an autoimmune condition. The path continues...

So what are treatments besides meds?

@PsychiatrySimplified

Жыл бұрын

In milder cases, many supplements have been covered in another video - It depends on the symptoms. Iron deficiency Vit B 12 folate Vit D are some aspects to ensure that they are adequately supplemented. evidence exists for NAC and some other non-medications. kzread.info/dash/bejne/jKOOps6wpqzdY7Q.html

@B3l0v3d05

Жыл бұрын

And brain retraining programs like Gupta, DNRS, etc. Also NSDR like Yoga Nidra

It’s a lot of information how the heck do you have any idea what you have and what needs to be treated?

Can you please suggest what can be done for those that crash from medication’s?

@PsychiatrySimplified

10 ай бұрын

Crash ( I’m assuming is fatigue & cognitive Sx & hyperarousal ) can be due to range of reasons 1. Hyperarousal not addressed 2. Agents for fatigue and cognitive improvement not lasting through whole day ( use longer acting agents AND / OR greater DA / NA potentiators) 3. Combination of 1+2. This addressing a crash wouid need to address these points

@elizabethread6878

10 ай бұрын

@@PsychiatrySimplified Yeah extreme hyperarousal but also initial fatigue. And then pots from it all. So you would give can you give me example of a DA or an NA that you would also give alongside with something for the hyper arousal the seem contradictory? I’m in severe distress I cannot even handle the noise outside I cannot sleep at all now I cannot handle anything severe pressure in my head I’m like I’m being pulled apulled upward my body will not calm down. I cannot even anticipate somebody coming into my room without me spiraling out of control into a deeper crash. What do you think that the suggest that I need? I can’t handle anticipations only thing that’s ever helped a little is Ativan But I keep crashing from every pill I put in my body I don’t know how to stop that. Do you have any advice for that? Even on regular Ativan I crash every time I take it

@elizabethread6878

10 ай бұрын

@@PsychiatrySimplified And thank you I appreciate it my biggest struggle has been crashing from everything every drug that I swallow immediately

@elizabethread6878

10 ай бұрын

@@PsychiatrySimplified I would feel like my entire body was shutting down I would get severe emotional problems I would scream and yell and I would eventually have to lay down and just lock myself in the room with in the dark with no noise until things calm down I will not be able to stand again until this happened till it all calmed. But it could start with severe severe tiredness and then go into the severe state of horridness as well. I would become suicidal. I don’t know what to do because I have so many symptoms. When I wasn’t as bad as Ativan brought me back to life but since I’ve been crashing from medicine over three years and food I have not been able to get this under control. Any of the medication‘s for pots that work just on the peripheral just crash me and make things worse. Like I said Ativan is the only thing that has given any relief but since it crashes me I don’t know how to get out of this cycle. And now I don’t think it’s strong enough. But if I just take something to calm down the activation I might be stuck with severe fatigue underneath it

@elizabethread6878

10 ай бұрын

I don’t know what’s causing the pots. Had 1 million test done. My blood pressure never showed extremely low when I would stand But the fact that I would get extreme tiredness initially could signal that I was having some sort of a blood pressure drop I’m not sure or maybe something else happening I have no idea

Can you please comment on what to do if you crash from every medication you take to try to help you get better? The second I swallow Ativan my body goes crazy. It happens with any medication I take or any food I eat. Mass cell specialist said he didn’t think that was the cause which is odd.. but can be hard to diagnose. Ativan is the onlythe only drug that calm things down but I cannot fully pull out of this because I’m constantly crashing or being activated by everything I put in my body. Do you have any recommendations or comments on this?

@elizabethread6878

11 ай бұрын

How do you know if you need to stimulate the frontal lobe and not just calm down the limbic system? My brain mapping showed my limbic system was way over active. I constantly am suffocating and cannot breathe so I cannot do anything because of it and it causes severe head pressure. But I crash from everything I take no doctor has been able to help yet. Do you have any thing to share? Also have parts from the crashing that would come that would begin with sudden extreme tiredness and then I would crash and get into a hyper active state with severe head pressure anxiety and could not tolerate even the slightest noise or anything I just currently cannot even speak to anybody I’m in a dark room. Any help is advised

@PsychiatrySimplified

10 ай бұрын

I'm so sorry to hear all this. In principle yes the limbic system is the one to address - these are all arousal reducing medications, benzodiazepines, mood stabilizers, clonidine, prazosin, low dose antipsychotic meds : the use of them is determined by the doctor who will consider teh severity. It's impossible to provide a specific recommendation as that depends on the examination.

@elizabethread6878

10 ай бұрын

@@PsychiatrySimplified Also o have seen in working with many doctors but I can’t get a psychiatrist prescribe me a mood stabilizer. I would need something that worked really really quickly otherwise I would just keep crashing until it worked. I have not tried clonidine or guanfacine I’m afraid to but if I can come the limbic system down I am open to it I’m just afraid of crashing from it and then it not helping. Any more advice to stop crashing from the drugs will help me so much thank you. I’m one step away from not being able to handle this anymore

@elizabethread6878

10 ай бұрын

Most importantly I need to stop the crashing from every drug that I try to take. As included details below any input is extremely extremely important so I can go to my doctors and try to figure this out. We have not been able to stop my crashing for three years but I am also not been tried on a lot of different medicines. I crashed a second I am inges anything

@elizabethread6878

10 ай бұрын

@@PsychiatrySimplified I have listed a few different comments if you could respond to each one I would appreciate it more than you can ever know. My one other question is how long does it take for guanfacine and clonidine to start working? Does it work similarly to benzodiazepines because these are the only things out of every relieved me some even though they crash me first

Thank you for all your videos! Do you only practice in Australia? I’d really like to see a great psychiatrist like you.

@PsychiatrySimplified

Жыл бұрын

Thanks for the feedback 🙏🏼. Yes in Australia.

@user-sf3qr6jt9j

Жыл бұрын

@@PsychiatrySimplified you’re welcome. Are there any physiatrists you know in the US or recommend, especially in NYC area?

@PsychiatrySimplified

Жыл бұрын

@@user-sf3qr6jt9j sorry don’t know of any specialists in US.

@user-sf3qr6jt9j

Жыл бұрын

@@PsychiatrySimplified It’s no problem, thank you replying

The body seems to have absolutely no desire to do anything concerning homeostasis when it comes to brain and neurological disorders. Indeed, it seems the opposite, that if one little thing can go wrong somewhere in these systems, the body revels in a positive feedback loop, getting sicker and sicker and reveling in the complete breakdown of the body. (This is rather a strong statement. I am a journalist/researcher and my estate is willed to physiological study of brain diseases. I have personal experiences. Nothing makes me feel more like vomiting than to listen to nature doctors say the "good body" will heal itself if you take care of it. More like the bad body needs a sledgehammer hit to get its attention, to consider supporting the soul within, or perish!)

Your shirt was not ironed . Just saying . Good video . Thanks for upload . Cheers

@PsychiatrySimplified

4 ай бұрын

😃 I was in bali filming 8 hrs 3 days in a row. Thought I’d be forgiven for a few crinkles. Thanks for the feedback 🙏🏻

@mariasperduti5316

10 күн бұрын

@@PsychiatrySimplified You look fabulous and sound brilliant. Forget the shirt. Keep sharing your knowledge and know you are appreciated.

This video too complicated what is the option for pots ? I also take beta blocker ! Is it not good to take it afraid to take it but no choice just don’t know how to bring down heart rate

@PsychiatrySimplified

6 ай бұрын

I’ve covered it in the video. It’s not something that can be oversimplified. Perhaps consider viewing it in parts slowing it down?

I had PEM for 2 years, POTS for 4 years Only have OI when doing sports. Hope that reslove too. It's a biological condition, but physiotherapy is need it for cleaning all the bad patterns in you and to build a new patrens for dealing this state. Only when it's clean you can star rebulding and the body should folow... When you get life back it's become some sort of a hobbie.😉 With Love, Mike

Who's best to see in UK like yourself nightmare so Asperger's heds change automatic nervous system my father had CFS to but was his thyroid.in.the end sure he has ADHD

@PsychiatrySimplified

Жыл бұрын

Sorry I don't know about specialists in the UK. Local doctors may know more

Could Seroquel cause hyperadregenic pots?

@barnbrac2452

9 ай бұрын

Based on dopamine reduction

@PsychiatrySimplified

9 ай бұрын

It’s not an easy question to answer because there are so many variables 1. The specific symptoms of CFS / hyperarousal 2. Dose of seroquel 3. The intensity of symptoms 4. Coexisting medications 5. The specific aspects of POTS. In general seroquel low doses is used to reduce central hyperadrenergic activity but has a dose dependent effect - too much and this could lose effectiveness.

@barnbrac2452

9 ай бұрын

@@PsychiatrySimplified Thank you so much for your reply. I’m in the unenviable position of getting Covid at the same time as being given diazepam @10mg. Then when I started getting tachycardia and breathlessness I was disbelieved by psychiatrists who put me on 75mg Seroquel. I am also on 30mg mirtazapine. On trying to reduce diazepam after 8 months (to stabilise) I got to 8mg and suddenly became dizzy. After extensive research I am querying if it is long covid or diazepam that caused hyperadregenic POTS. Also the norepinephrine from mirtazapine, perhaps causing or exacerbating POTS. Strangely my symptoms of anxiety (reduced adrenaline / cortisol) when I take the mirtazapine in the evening is the only relief I get. My thinking is the antihistamine effect initially alleviates followed by next day adrenaline surges from norepinephrine increase next day. Basically I feel that I’m screw** by comorbidities influenced by psychiatry and as I know you’ll know that benzo withdrawal is brutal on its own, but with dysautonomia what chance do I have a. Getting traditional POTS treatment (and what cardiologist / neurologist would ever know or want to attempt a multi-disciplinary approach to treatment)? Doomed.

@barnbrac2452

9 ай бұрын

And b how could I (or a practitioner) ever differentiate between the myriad of drugs and atypical iatrogenic harm these atypically cause in combination (e.g both NICE and BNF in UK strongly advise against antipsychotics in Benzodiazapine withdrawal). I was forced to take Seroquel or be forced with a section (due to non compliance) as they would not believe (gaslighting) that I was suffering from multiple side effects, because a single ECG was normal. I strongly believe that I had Covid related symptoms and the beginning of dysautonomia at this time. Any advice on how I can ever get out of this mess would be much appreciated, I was strongly committed to reducing and getting off diazepam but how do you proceed with POTS and contraindicated medications?

@barnbrac2452

9 ай бұрын

Finally everything got significantly worse after quetiapine. No informed consent on any of these medications. I had to do the research myself. Significant cognitive impairments plus akathisia and I believe Tardive dyskinesia. 3 year waiting list to see a neurologist. I was a public health manager before all this madness (albeit I had no idea that benzos I was prescribed had dependency issues over 3 weeks, just addiction and I knew I wouldn’t become addicted). I was originally prescribed 15mg plus 7.5 mg zopiclone! If I could stop taking all the drugs today I would. Thank you in advance for any advice!

And if you have 1 million symptoms at rest how do you know what is wrong and what needs to be treated. Even if you do have pots how do you know what you need to do or what is wrong in your body how are you supposed to figure that out? The only test that I’ve seen on here basically is a standing test measure Norepinephrine levels to see if you have central nervous system pots or not. What are we supposed to do to figure this out and to get better? And then how do we know what we need to take her do to get better? This is what needs to be addressed mostly because we can watch his videos all day long but nothing is helping us get better know Dr is helping us get better and there’s no instruction in here what we’re supposed to do

@elizabethread6878

Жыл бұрын

For example how do you even know if you have the first type of path with the nerve issue in the leg? There are all these things that are listed but it drives us nuts because how are we supposed to figure out what the heck we have even with autonomic testing they typically do not tell you and cannot differentiate. And this is so much more than what happens when you stand. What about the millions of symptoms and severe distressed that you’re in when you’re laying down? How are you supposed to figure out what your dysfunction is then you don’t even have to stand up to figure out that you have severe problems so how do you test is to figure it out aside from those antibody test and once those are eliminated then what? Where is the instruction on how to get better and what do you do if you’re lacking the norepinephrine thing and so then your body is producing way too much? How do you fix that problem? It needs to be discussed how you figure out which you problems you have and then what the answers to fixing them are and then maybe people can start going to doctors telling them what they need to do and get better. I mean this with the most respected I watch three of these videos and I am two steps away from any of my life because of all of this with better instruction lives could be saved I know you were doing the best more than anybody else but these steps need to be incorporated so people can take action

@elizabethread6878

Жыл бұрын

And then what medication do you take what do you take if you have central nervous system pot? What do you take if you have severe anxiety distress suffocation all the time at rest only how do you know if you are in sympathetic or parasympathetic access how do you know what medication you need what do you do if you crash from every medicine you put in your body? Again there’s no instruction. What are we supposed to do to get better without it? We could watch these videos all day long if we cannot figure out what is wrong in our body we cannot do anything about it and if we do not know what to do once we know and then we also cannot do anything about it

@PsychiatrySimplified

Жыл бұрын

The questions you ask are very pertinent. Here is someone who is very knowledgeable in the US . Hopefully they can help as they run a clinic. - www.dysautonomiaclinic.com/dr-blitshteyn/

@elizabethread6878

Жыл бұрын

@@PsychiatrySimplified Thank you I did a consult with her she told me to take a low-dose of anti-histamine which I don’t tolerate because I don’t tolerate any medication so I couldn’t do it. And then she was gonna give me a 10 lol she’s not understanding that I have severe chronic fatigue syndrome and that these drugs are crashing me. She thought I was having an allergic reaction but the truth is if I put one of those Claritin drugs in me that she suggested all it would do is crash me more so I never did it. What do you suggest for people that have this problem?

@elizabethread6878

Жыл бұрын

@@PsychiatrySimplified I have tried to work with her at all she told me to take with Claritin because I crash from everything but I wouldn’t take it because it will crash me. In the past you have told me the different types of medicines that calm down the limbic system. Can you please list those medications out you said there a drug stronger than Ativan you listed them I just can’t find it because I can’t even breathe and Read at the same time I’m in such bad shape. You listed benzodiazepines and then some other things maybe Lamontrogone I can’t quite remember and maybe guanfacine or clonidine. I need to be able to discuss this with my doctor is there anyway you could just listen if in order of strength like you did in the past things to calm down the limbic system because my brain mapping showed mine is very overactive. We had the conversation in the past I just can’t find it. Thank you so much I know it is not medical advice I’m just asking what medication to calm the limbic system and if Ativan is not enough what other medication’s exist so I can talk to my psychiatrist. I am begging you please thank you

Ehlers danlos subclinically is the major problem

@PsychiatrySimplified

4 ай бұрын

Yes it is part of the wider issue

@oliverbird6914

4 ай бұрын

@@PsychiatrySimplified are you aware of the rcccx theory doc. I think it's very persuasive

⭐⭐⭐⭐⭐

What happens in your body during a crash? What is a crash? No one has ever been able to explain this. Thank you

@PsychiatrySimplified

10 ай бұрын

Everyone’s experience of brash is different : so question would be what are Sx. Some experience return of fatigue & poor cognition which is significant while others a wired fatigue while others mainly feeling wired .

@elizabethread6878

10 ай бұрын

@@PsychiatrySimplified mine could start with extreme pressure in my head extreme irritability and then the inability to stand up anymore. And then go into a state where I can barely even form sentences sometimes with extreme fatigue also sometimes there was severe anxiety severe pressure in my head severe hyperactivity it’s in the sensitivity to everything around me noise etc. etc. It could start with extreme tiredness and go from there or it could start with kicking my whole nervous system into higher gear depending on what is triggering it. I am in such severe misery right now I don’t know what to do. Do you have any recommendations for how to handle stopping the crashing every time you take a medication? As soon as I would swallow a pill I would get pressure in my head internal vertigo and eventually I would not be able to stand up anymore and then I would be in my bed for hours my whole body would be like locked down it felt not just from a state of fatigue but like I literally could not move without my heart going insane and everything spinning I don’t even know how to explain it severe pressure in my head in ability to think read taken any information or breathe properly. It’s just a complete disaster and I have no idea what I’m supposed to do because they keep crashing from drugs. What would you recommend in the situation? As soon as I swallow my Ativan my heart starts going I start breathing faster I get more pressure in my head I feel like my head is being pushed out of my body. And then once it starts to work it calms down a little but it’s not enough I’m not getting it under control it’s gotten severely worse. What do you think is necessary? I don’t know my test showed extra parasympathetic and sympathetic activation but at the extra parasympathetic was the main problem and the sympathetic with secondary. I don’t know what to do I think it’s stimulant would probably destroy me I have no idea I have pots and I’m fully bedridden. The Ativan helps calm it down but I really don’t know what to do I don’t know what drug medication I need

@elizabethread6878

10 ай бұрын

When I will get the bad farofie before it would come with terrible cognition. Right now I’m so in such distress I literally am screaming and I cannot calm down my nervous system so I don’t know what that means because I’ve never I don’t know what other people experience but I literally am screaming in my room because I am in such distress from the activation or whatever that feels it

@elizabethread6878

10 ай бұрын

When I will get the bad farofie before it would come with terrible cognition. Right now I’m so in such distress I literally am screaming and I cannot calm down my nervous system so I don’t know what that means because I’ve never I don’t know what other people experience but I literally am screaming in my room because I am in such distress from the activation or whatever that feels it is

@elizabethread6878

10 ай бұрын

@@PsychiatrySimplified eventually before when I wasn’t as bad I would feel like I was being pulled down to the floor by an 80 pound weight if I try to stand up I could even have that feeling laying down some feeling that all the sudden something is activated in me and pushing my head and then eventually they got to the point where I was like slurring my words in bed and felt trapped in my body. This happened when I took an SSRI for the first time without any Ativan. This is how my body responds to medication. I have no idea what I need because I have so many mixed symptoms I just know I need to help and no one is able to tell me what the right thing is for me

This is the most important video I have heard regarding these topics, yet you completely ruin it for the listener by speaking so fast and cutting out all your natural pauses!!! It's 37 minutes of solid fast talking!! What were you thinking?! Even people without all these neurological issues will have a difficult time listening to this!! I am 3/4 the way through and my brain sensitivities are screaming! 😭

@greatnationnow

6 ай бұрын

This was even while slowing the playback speed!

@PsychiatrySimplified

6 ай бұрын

Thanks for the feedback. I’ve left the slowing down to playback adjustment as some other videos talked about a slower pace hence them needing to speed it up

When are you going to add cancer diabetes and heart disease to this limited list

i believe the main audience of tgis video and other similar videos should be medical proffesionals not us as the patients! i wish u could make other doctors pay more attention to these conditions and help them learn more about them by conducting conferences, workshops for them, etc... so that ww wouldn't keep getting dissmised or gaslighted. some of us have really horrible experince going to the doctos and bc of some of those doctors humiliating us, even our families have started to doubt if we really need help! Do you think your colleagea like to get preached on what are the real causes of these by a patient?! absoloutely not! at the end of the day we are still in need of professional help and we just have so much information that we can't really put to use bc of our physical limits :)

@metali1378

Ай бұрын

we can't prescribe those meds for ourselves Dr! and i dont know abt other parts of the world but in my country all they prescribe is beta blockers and anti depressants. when i talked abt methyl phenidate with a doctor and even provided the article for that, they laughed at me and then scolded me for "googling" or reading too much . again, in their minds, it all comes back to us being hysterical or delusional and trying to find nonexistent illnesses for ourselves just bc we are depressed or in need of attention.

@metali1378

Ай бұрын

this is more of an acceptance issue in the proud medical field rather than lack of research.

@PsychiatrySimplified

Ай бұрын

I understand what you mean. One of the challenges is reaching different specialties while recognising the value of psychiatric education in these conditions. It's crucial to look at the overall picture rather than splitting it into specialties. Psychiatry often doesn't get the recognition it deserves, even though it involves neuropsychiatry, psychocardiology, psychoneurology, and more. We have developed an intense, comprehensive curriculum for doctors, accredited - www.academy.psychscene.com/courses/neuroscience-to-clinical-practice-the-neuropsychiatry-of-chronic-fatigue-syndrome-and-long-covid/ This curriculum covers chronic fatigue syndrome, long COVID, fibromyalgia, POTS, EDS, muscle activation, and includes case studies on the implementation of medication and patient progress. I know firsthand that patients can improve significantly, though science advances slowly, and pushing material can sometimes backfire. Through KZread talks and the Academy, I hope recognition of these conditions will increase, ultimately improving patient lives. Thank you for raising this point; I wholeheartedly agree.

@PsychiatrySimplified

Ай бұрын

I’m sorry to hear. Yes many are dismissed

"Promo sm"

#moldexposure #moldtoxicity #indoorairquality

Caused by ghosts just watch any episode of dead files

talk to quick for me

@alicequayle4625

3 ай бұрын

You can slow it down. Tap on the cog.

@PsychiatrySimplified

3 ай бұрын

Reduce the speed

This is truly a very very well done video. My ex believes that l-dopa helps cerebral hypoperfusion in someways. It was actually I very interesting theory and I've love to hear if you have any thoughts on it. It certainly is useful for people with hEDS.

@PsychiatrySimplified

Жыл бұрын

Thank you for your feedback. Dopamine is closely linked to cerebral perfusion. As it is an endogenous vasodilator. Similar increase in perfusion is seen with stimulants. Another under recognised aspect is that Dopaminergic potentiation has anti inflammatory properties .

@douglasman100

Жыл бұрын

@@PsychiatrySimplified Yes I saw that study a little while ago, l-dopa and d-amp used for neuroinflammation based depression or something like that. Have you looked into the further use of l-dopa for dystonia and dysautonomia in EDS? Seems relevant to this whole connection.

@PsychiatrySimplified

Жыл бұрын

@@douglasman100 Used methylphenidate/armodafinil etc, very successfully in dysautonomia - importantly, it often needs a reduction of hyperarousal first, so alpha 2 agonists help with that. This is a huge field w- we just completed a 7.5 hr webinar series on this - which will be released on the academy soon for health professionals.

Wait I just realized how many jumpcuts there are in this. Is this cut from longer form content? because if so it's really well done...

@PsychiatrySimplified

Жыл бұрын

Original video was about 40-42 mins I think .

Will you please get back to me on what to do when you are crashing from medication that you put in your body? The crash can feel like out you are sunk in a hole you cannot use your brain but you’re also extremely agitated. You cannot breathe and you are struggling very very badly to the point that you literally cannot handle it. Thank you so much what type of medication’s are needed or what can be done for this?

@PsychiatrySimplified

3 ай бұрын

Please see the latest video on anxiety, hyperarousal and agitation and the differences between them. That should help understand what needs to be targeted