These videos is the only thing i look forward to at the moment. Thank you very much for helping all of us suffering.

@5ilentRage

3 жыл бұрын

You and me both. Honestly such good work

@dedesunbeam9361

3 жыл бұрын

@@5ilentRage You and me and August! A lifesaver.

@lauraanderson3611

2 жыл бұрын

Hang in there. It will get better slowly.

You’ve been significantly more helpful than any doctor I’ve seen in person. Thank you!

@RUNDMC1

3 жыл бұрын

Sorry you’ve had such a rough experience Meir. There are good doctors out there! Where are you based?

@meirwilenkin9218

3 жыл бұрын

@@RUNDMC1 I live in Brooklyn, NY. Until recently, most doctors that I’ve seen told me it was all anxiety- I thought I was crazy until I came across your channel. You’re doing such amazing work.

@philweaver457

3 жыл бұрын

so true!

@victoriamccullom2599

3 жыл бұрын

@@meirwilenkin9218 me too

@gloriaanderson7424

3 жыл бұрын

But why are most doctors no helpful?

I started on 500mg of niacin last Friday and whoah, DO NOT DO THAT, FRIENDS! I ordered some 50mg pills and have been on them the past few days. I honestly am feeling better. My brain is working again, my body temperature is starting to regulate a bit better, tinnitus is quieting and my breathing starting to almost feel normal. Thank you so much for these videos. You’ve helped so many people!

@RUNDMC1

3 жыл бұрын

Thanks Greg! And yes - 500mg of Niacin can be quite the rush!

@frankttom4990

3 жыл бұрын

Greg Garner, which other long haul symptoms did you have? Was your tinnitus also variable depending on the day?

@ChristianSkoda

3 жыл бұрын

I started with 1x 250mg Niacin capsules once a day and upped to 500mg after 1 week (taken after lunch), controlling the flush comfortably with 1x aspirin taken before lunch. Should I reduce the dose better again or keep it that way, as it's bearable? I'm 2 weeks at it and there is a slight improvement in energy, although nothing dramatic.

@GregGarner

3 жыл бұрын

@@frankttom4990 I first had symptoms back in the middle of March but wasn’t able to get tested until three weeks later and the Covid test was negative. Also tested negative for antibodies. But I’ve had breathing issues, tachycardia and palpitations, fatigue, hot skin which leads to feeling cold, intolerance to exercise and direct sunlight, tinnitus off and on but more pronounced since October, intermittent sore throat and feeling slightly feverish. The tinnitus has been worse on some days. Interestingly, since starting the niacin, I’ve noticed some sneezing and, inflamed eyes and generally classic histamine/allergy feeling. Haven’t had this before during any of this. Anyone else experienced this?

@RUNDMC1

3 жыл бұрын

Christian Skoda Bring it back down to 250 and keep it there for a few weeks

God, I really hope this is it... I’ve just ordered these supplements as I’ve had this since March and want to get my old life back. Thank you

@RUNDMC1

3 жыл бұрын

We all want our old lives back! Best of luck in your recovery Zac 👍

@philweaver457

3 жыл бұрын

I have good feelings about it. Im already feeling much better. I was already taking everything but the b3. That made all the difference. good luck to you

@JoButterwick

3 жыл бұрын

Please heed the advice to start B3 on a low dose. I took100mg, The "flush" was much more than expected and I spent the evening in A&E. I still have brusing around my eyes from the swelling. Not recommended!

@RUNDMC1

3 жыл бұрын

Phil Weaver glad to hear it!

@janeathome6643

3 жыл бұрын

Please see my other comments; the changes I'm seeing are pretty dramatic.

Gotta love a man who drops an heironymus bosch painting with sound effect into a covid video lol

@RUNDMC1

3 жыл бұрын

Knew someone would appreciate it!

@christinecortese9973

3 жыл бұрын

@@RUNDMC1 it gave me a good belly laugh!

I was already following an "anti-inflammatory" diet since contracting Covid in March, but following the last video, I realized that I had to add/delete a variety of foods and supplements and made those changes to the best of my ability, and I am already seeing some really positive results in my symptoms (almost all of which seem attributable to inflammation, presumably due to a mast cell feedback loop. It now feels possible that with time, I can interrupt that feedback loop. All of my symptoms have shown improvement (neurological, bronchial, gastrointestinal). They are still present, but I've actually been able to cut down on some of my medicine intake for treatment of those symptoms. One of the most dramatic changes was a complete return to normal of my pulse rate and a regular modulated body temperature, consistent to what it was prior to my infection.

@RUNDMC1

3 жыл бұрын

Very glad to hear of your improvement Jane!

@ChristianSkoda

3 жыл бұрын

Jane, could you elaborate a bit more please of what you added & removed from your anti-inflammatory diet? Thank you!

@janeathome6643

3 жыл бұрын

@@ChristianSkoda I specifically added a high dose of Niacin, upped my vitamin C, added a pretty high dose of quercetin (already taking upper level doses of vitamins D and K, zinc, magnesium, other Bs. I cut out bananas, spinach, avocados, tomatoes, green tea (I was drinking a lot of that), absolutely all gluten, citrus, and started taking a benadryl every night. I was able to eliminate cough suppressant though still taking expectorant and singulair, haven't thought about using my enhaler, have started to forget/skip my reflux meds; fewer headaches, reduced dizziness and brain fog, fewer memory issues, better word recall. I had no idea until the part 1of this video that there were so many mast cell triggers labeled as supposedly good for you and anti -inflammatory.

@itstolgs

3 жыл бұрын

@@janeathome6643 Hi Jane - how high was your niacin intake? I’m taking around 150 mgs a day

@janeathome6643

3 жыл бұрын

@@itstolgs 300 mgs, but I'm older than you.

From another exhausted, frustrated, and discouraged Long Hauler, THANK YOU!💙 I'm at 8.5 months and just started 100mg of niacin two weeks ago. Though I had a terrible relapse yesterday (first time in months, thinking it may have something to do with my menstrual cycle?). Sticking with the niacin though! I've limited sugar the last few months but am going to try limiting high histamine foods👍. I pray for us all and I cannot wait for the day when we are healed and there IS an answer! Thank you again!

@RUNDMC1

3 жыл бұрын

That’s OK Jenny. Hope it helps with your recovery!

@easy_sheets

2 жыл бұрын

did you ever recover?

Another excellent video - and not least because Dr. Richards gave me hope again

Your input on long covid is truly appreciated. I have implemented some of the advice from your channel and I have seen improvements. It gives us all a little nugget of hope. Thank you!

Jackpot! I knew it. Thank you for your devotion 😊

Another video already? Gez, you are spoiling us 😁 Loved the painting at the end

@RUNDMC1

3 жыл бұрын

Haha. Thanks Alison!

A thousand thanks to you for sharing the best summary of the most relevant information about Long Covid. You're such a blessing to so many of us fortunate enough to have found your channel. Thank you for interviewing Dr. Wentzel, and also for summarizing the high points from Part 1 of your excellent "Biology of Long Covid" series. I love all the detailed information, too--and paused this video at several points to better absorb the significance of some of these key puzzle pieces you've been finding. And thanks for the good laugh at the end!

@RUNDMC1

3 жыл бұрын

Thank you Cynthia! Glad you appreciate it 😊

Awesome encapsulation and presentation of medical clinicians and researchers on the leading curve. Thank you!

@RUNDMC1

3 жыл бұрын

Pleasure :)

RUN-DMC your videos are always so intellectually alert and socially adapt. I enjoy hearing from you.

@RUNDMC1

3 жыл бұрын

Thanks Nicole!

@nicoleluella2134

3 жыл бұрын

If you have some time you should check out Dr. John Campbell info on vaccines? Video title pandemic, Tuesday 15th December.

Thank you Gez!!! Thanks to Dr. Wentzel and his team for this gem. I wish I had this information before developing POTS. Hope that this is the answer that I have been looking for 9 months.

@RUNDMC1

3 жыл бұрын

Hope so too! 🤞

@harryvanda684

4 ай бұрын

How are you doing now?

This is fascinating! Thank you so much for your efforts, putting this together, Gez. Hopefully , in time this regimen will bring the much - needed relief to many Long Haulers and COVID will have finally done us a favour in understanding genetic changes and damage to metabolic pathways as part of disease etiology. Cx

@RUNDMC1

3 жыл бұрын

Thank you Carol! 😊

This doctor is amazing, and his story mirrors mine exactly - mild covid, period of exercise, then a crash. And yes, I also have chest pain and tachycardia, with all heart tests showing normal. I have been taking antihistamines and nycin for a couple of weeks now and I am really making great progress! I take all the vitamins too. I just hope I can get more time off work so I can properly recover. I can handle 250mg niacin not too bad, but will probably now split it 150 x3. Thank you both so much, you have given me hope that I can get my life back!

I’m very happy to see you looking more sanguine and healthy. Wonderful.

@RUNDMC1

3 жыл бұрын

Haha, thank you!

Thank you from Canada (Quebec) ! You are my moral booster. Merciiiiii

@RUNDMC1

3 жыл бұрын

De rien Julie!

@Aradia10

3 жыл бұрын

Oui, moi aussi! Mon Brit favori!

Im starting to feel like my piece of the puzzle is the one my younger sibling lost the last time they put the puzzle away. Im blessed to only have leg muscle weakness, but it does feel a bit like a one off. Thanks again for keeping us informed!

@kesses9041

3 жыл бұрын

I know that feeling (but after taking a lot of supplements, and ashwagandha I can actually feel the muscles reacting again!) Don't give up hope. 🙏💜

Thank you so much again. This time I almost saw some light in the tunnel

@RUNDMC1

3 жыл бұрын

It is out there in front of us Eva!

My apartment is looking like a pharmacy. No improvement 1 week into the regiment, but still hopeful, with Dr Wentzel saying it can take months even. As always, thank you for another extremely useful video.

@RUNDMC1

3 жыл бұрын

Hang tight Tim!

@frankttom4990

3 жыл бұрын

Tim Clark which were your long Covid symptoms and when did you get infected?

@moiseechen

3 жыл бұрын

thanks for posting; i too have quite the collection of additives. day 5 for me, and no improvement w wretched fatigue. i also do Intermittent fasting and keto. and still hopeful too! and persistent.

@tanyaclarke268

3 жыл бұрын

Have you got the niacin, it has to be the flush one ... nicotinic acid. It's working for me slowly for sure - good luck

Thank you Gez! Taking niacin has helped me greatly in just a week. The dark circles under your eyes have really improved! 😯 We are seeing the changes with each video. 🙌🏼

@RUNDMC1

3 жыл бұрын

That might just depend on whether I’ve shot the video on a good day or a bad day! But thanks! :)

@browneyedgirlFL67

2 жыл бұрын

How much (dosage) niacin did you start out with and did you increase over time? Can you recommend a brand? Thanks @Karla Adair

@karlaadair6540

2 жыл бұрын

@@browneyedgirlFL67 Orthomolecular brand. 500mg about every other day for a month or two. Now I just take it here and there.

@browneyedgirlFL67

2 жыл бұрын

@@karlaadair6540 why did I think it needed to be taken three times a day after a meal? Did you start out at 500mg ? And when did you notice a positive change?

@karlaadair6540

2 жыл бұрын

@@browneyedgirlFL67 it just felt powerful and like it was plenty so I just listened to my body. My tongue felt less “swollen” in about 3 days. Felt less fatigue in about 2 weeks.

Bravo! Bravo! Thank you, Gez! We are finally getting a better understanding and and encouraging news it's not likey to be permanent! I so needed confirmation on this! And tonight is Day 8 of Hanukkah... it's a Hanukkah Miracle!! 🤩

@RUNDMC1

3 жыл бұрын

Haha, definitely!

Run-DMC, one supplement (in addition to those you discuss) that has been over the top healing to me so far (other than high Vit C) has been high doses of Magnesium Chloride. I think that cfs and long covid get triggered when the adrenal gland gets gassed and can't keep up with long term infection fighting. Then, the body can't clear the virus, then the NAD problem and MAST cell issues come on. The body stays in this low energy state, preventing it from clearing the virus, because the adrenals and thyroid can't keep up, so they go off line. All of the inflammation from the Mast issues compound the issue, convincing the adrenals to stay off line. The key is to convince the adrenals and thyroid that they can turn back on at full energy, either by lowering pathogen levels or adding enough nutrition to significantly lower the inflammation. So to my mind, supporting the adrenals and thyroid with what they need is as important as addressing the Mast Cell inflammation. Thyroid needs Iodine, Selenium, B vitamins and Zinc. The adrenals need 2 things in huge amounts to survive a long infection: Vitamin C and Magnesium. Most animals make their own Vitamin C. Humans do not. Linus Pauling who discovered Vitamin C took 20 grams (not mgs) per day, to give you an idea of what he thought was a health optimizing dose. Magnesium is arguably needed in just as high doses. Interestingly, I stumbled upon Magnesium Chloride because I was looking for an anti-viral that would kill Covid, as my previous success with CFS involved killing the virus, ebv. Magnesium Chloride kills almost everything apparently, but at the same time does not add stress or inflammation to the body or damage tissues because its magnesium. It is a tonic that aids sleep and ends anxiety and palpitations. A doctor named Pierre Delbet discovered that Magnesium Chloride had this magic during WWI, and he used it against polio and many other things. I have linked a website here that describes how I take it. I am currently taking 3mg, 3x per day dissolved in water. It's cheap, and it is the one supplement I take (I take a ton) that brought me up about 40%. I plan to take it long term, because I am hoping it will kill covid and support my adrenals. It increases immune function by 300%. Only magnesium chloride by mouth, not any other kind of magnesium will work. Here is the link. www.mgwater.com/vergini.shtml If it works for you, perhaps you can share about it on your channel. I find it fascinating that mainstream medicine rejected their attempts to promote it as an anti-viral and antibiotic in the 1930's and 40's in favor of vaccinations.

Thanks for all you do Gez! You will deserve a knighthood by the end of all of this!!! Buying the niacin now, adding it to my large collection of supplements, fingers crossed! The dietary supplements industry must be doing well this year! ;-)

@RUNDMC1

3 жыл бұрын

Thanks Sarah - hope it does help your recovery!

Another excellent video mate! Thanks for all your work and effort. How are you feeling these days?

@RUNDMC1

3 жыл бұрын

Improving!

@toshawhalon4727

3 жыл бұрын

@@RUNDMC1 when did u first get the virus

@RUNDMC1

3 жыл бұрын

Tosha Whalon March

@Billiardroomsessions

3 жыл бұрын

@@RUNDMC1 have you tried fasting at all? I’ve been reading that a mixture of intermittent fasting, twined with a 3 day water fast will induce autophagy and perhaps clear out some of the virus that might still be in our bodies?!

thank you so much. I started the stack right after your last video and have been getting great results. So grateful to be mostly rid of that body buzz and tinnitus.

@RUNDMC1

3 жыл бұрын

Glad to hear it’s working Phil!

@frankttom4990

3 жыл бұрын

Phil Weaver, did your tinnitus really improve after this?

@frankttom4990

3 жыл бұрын

And by the way, which other symptoms did you have?

@alisonhoward6665

3 жыл бұрын

What’s “the stack”?

@philweaver457

3 жыл бұрын

@@frankttom4990 I had a few really good days. then relapsed badly. Today is better. Im at week 1 as of today. the follow up video to this says 1-2 weeks. So we will see.

Thank you so much for this informative video. Be well.

@RUNDMC1

3 жыл бұрын

You too Leslie!

Nice hopeful video conclusion

Wow, thanks!

Something of a genius Gez! Absolutely love the interview, wish I could have been a fly on your skis - very interesting that he doesn't recommend non-flushing Niacin. Did he say why? As always, thanks for a very clear vid!

@RUNDMC1

3 жыл бұрын

Thanks Michelle - it’s due to the absorption and which version is best used by the body.

@michelleg4895

3 жыл бұрын

@@RUNDMC1 It's interesting to see the similarities. Thanks for keeping on top of this, it's helpful to so many of us.

Your videos help me mote than any MD I have seen. That is a very significant statement.

@RUNDMC1

3 жыл бұрын

Thank you Max!

@PatrickBateman191

3 жыл бұрын

@@RUNDMC1 you deserve it. Well done.

Gez, you're a genius! And also a true HERO for all who are suffering this condition. A million thanks for your videos! How do you take these supps (meal wise)? All of them at breakfast or do you divide them between three/four meals a day?

@RUNDMC1

3 жыл бұрын

Thanks Frank! Split the niacin up over the day, same with quercetin. Others can be taken in the morning

Many thanks for your incredible work! I think you help more people than the average doctor. I wonder if creatine could have a role in the stack? It works with ATP/energy in the cells and also makes you load up with water in the body which may be helpful. Would be great to know more about it. Looking forward to your next video.

@RUNDMC1

3 жыл бұрын

I don’t think it would hurt - although if you’re suffering from inflammation already more water in the body may not be that helpful!

Gez, sorry if it's already been asked, but how are you feeling on the new regimen? Improved? I've been ill since June, and the supplements & diet change have made an improvement over the last fortnight or so, but I still need 12+ hours of sleep. Thanks so much for your videos and hard work over the last few months, despite your own illness -- they have been so helpful in so many ways. :-)

@RUNDMC1

3 жыл бұрын

Yes I’m feeling better - like you still needing lots of sleep though. 9 hours is my baseline or I’m all over the shop. Glad to hear you’re improving!

Thank you so much :)

@RUNDMC1

Жыл бұрын

No problem! :)

Another great video, I really enjoy these and it seems you are using decent scientists and medical staff for the content. I have started with the supplements as suggested in your video, I'm hoping there will be a positive in terms of my reaction to these. I do have a couple of questions for you, what are your principal ailments since catching covid? How badly were you ill with your initial symptoms? and finally how has your health improved over the last few months? I do hope there is more significant improvement with your health. Thanks again for the amazing videos.

@RUNDMC1

3 жыл бұрын

1) Brutal fatigue, headaches, cognitive issues, skin issues, palpitations, histamine intolerance, exercise intolerance 2) initial symptoms weren’t that bad - felt like a cross between a mild flu and norovirus. 3) Better the last 2-3 weeks after starting the various treatments and being more assiduous about low histamine diet.

@jcw1983jcw

3 жыл бұрын

@@RUNDMC1 I certainly share the fatigue and exercise intolerance, I suffer a lot with muscle pain and sometimes I am short of breath. Like you my initial symptoms were flu like, the first week was dominated by fatigue, muscle ache and weakness, in the second week I became short of breath and had chest pains. Glad to hear the treatments are working for you, I am following a similar path, I will go low histamine after Christmas. I hope your recovery continues.

Thanks again Gez

Hey Gez! first off thanks for this invaluable content. You ROCK Second, as request: Could you ask Dr Wentzel about Resveratrol? I've read some interesting things that as well as Quercetine it can promote autophagy which could be beneficial to get rid of V. presence in gut, although some studies suggest that if combined, the effect is actually reduced... Thanks in advance mate!

@RUNDMC1

3 жыл бұрын

I’ll try!

Awesome content, thank you! I've been taking Niacin for a while, MCAS symptoms improving a bit but still there. Would adding Methylene Blue be something to consider?

Thanks again for sharing your research! You should be nominated to Nobel! I did not quite understand: should we take nicotinic acid for getting well?

@RUNDMC1

3 жыл бұрын

Yes!

@kirim8621

3 жыл бұрын

@@RUNDMC1 right, after 8 months maybe this nicotinic acid is the answer for me too.

@shehnaaz5712

2 жыл бұрын

after 18 months, could this be the missing peice

Merry Christmas!!! ...from NY.

With all this new info and "pieces of the puzzle" coming to light, I wonder what all this new research might mean for the study of other diseases and conditions having nothing directly to do with covid 19. It would be nice if it sparks whole new lines of study deeper into the biochemistry and metabolic effects involved in those other diseases - and finds new answers and treatments no one knew to look for until now. If so, that would finally be something good out of covid.

@smitakamath2008

3 жыл бұрын

I sure hope that this is useful especially for ME/CFS. It is a tough condition to live with and tolerate

@fionalowe1907

3 жыл бұрын

I was thinking the same. In the future, Drs may look back at this time as being pivotal in understanding many debilitating health problems

@ysbyttybedbug

3 жыл бұрын

@@smitakamath2008 it’s why I have been following these videos with great interest. Praying that the answer to ME will be found in this research.

@chenanigans

3 жыл бұрын

I was thinking the same too. That maybe finally the healthcare industry will lean more towards a healthy lifestyle approach.

This is exactly what symptoms I have experienced with Chronic Lyme Disease...along with millions more. But, the doctors don't admit we exist...I hope and pray it does not happen to the long haulers...of which I am one. Pots was a big symptom with me in the beginning...still have to sit with my feet elevated...

Gez, this is the first time I have added in a comment from sunny (Summertime now), South Africa. I'm 6 months in with brain fog, fatigue and chronic, constant, unbearable pain in my left leg running down from my Covid induced arthritis in my hips. On Monday I am having an MRI on my spine and hips. Thereafter, nerve conduction testing in both legs as the doctors are thinking neuropathy, and as a diabetic who was fit and reversing the type 2 condition, diabetic neuropathy. I have been so alone in my struggle with this fickle, dishonest virus and your input is greatly appreciated and I value your tireless research, in spite of the restrictions, greatly. You are my "Be the change with Covid' hero. You have cheered me up with this latest video as you are looking a tad perkier.

@RUNDMC1

3 жыл бұрын

Thanks Anna :) I really hope you start to recover soon. I do recommend the treatments I’ve talked about in my latest films - got a study that shows they actually work coming out with my next film. Dr Wentzel is on to something!

@moiseechen

3 жыл бұрын

@@RUNDMC1 thanks SO much for your helpful videos. best of luck. i located this protocol summary: membrane.com/world/ but am unable to locate the study results. Have you a link? i'm taking 500 mg niacin/day, for 7 days now. still enormously fatigued. no improvement. yet. and i still do Intermittent fasting and keto. guess it can take months? esp if one is already NAD depleted. thanks again!

@RUNDMC1

3 жыл бұрын

Moiseechen yes I think it’s fair to expect recovery in the order of months rather than weeks

Thank you so much. The onset of symptoms after exercise describes my experience 100%. I have always wondered why ultra-fit people seemed to be affected to such an extent. It seems counter-intuitive. I am going to start with the recommended supplements immediately.

@RUNDMC1

3 жыл бұрын

Yes - I think ultra fit people have already been running with borderline NAD+ deficiency due to the heavy training. Makes sense with my experience too.

@robinhood4640

3 жыл бұрын

When you ask your body to do things, your body needs more air to be able to do it. The gas exchange in the lungs is different than when you are not doing anything. Women are more affected by men by the crap in the air because of the differences between men and women, this is why women are more likely to have systemic disfunction (autoimmunity) than men. Toxic overload. www.amchara.com/genetics-dna/gender-differences-in-chemical-exposure journals.physiology.org/doi/full/10.1152/jappl.1998.84.6.1872

@jcw1983jcw

3 жыл бұрын

I've got ongoing symptoms but did nothing other than moderate to light exercise after covid. I perhaps wonder if the cycle rides I did a couple of days before I displayed symptoms has caused my experience. I used to happily bike 15 miles each way for dinner in my parents garden. It knowing when I am ok to start exercising again, the last thing I want to do is set myself back.

@jetwaveboard6729

2 жыл бұрын

@@RUNDMC1 can I take NAD instead of Niacin?

For how Long has Dr Ade Wentzel been doing his NAD+ treatment? I'm wondering since he comments on his face beein flushed from the Niacin.

Thanks

Thanks again Gez, like someone else said, these videos have been more helpful than my GP. Could I ask, are nicotinic acid, niacin and vit B3 all the same thing?

@RUNDMC1

3 жыл бұрын

First two are the same but Vit B3 includes other forms like nicotinamide under the same umbrella (I think!)

@timsweeney1999

3 жыл бұрын

Hi, there is a good definition here www.healthline.com/nutrition/niacin-benefits Nicotinic acid: As a supplement, nicotinic acid is a form of niacin used to reduce cholesterol levels and lower your risk of heart disease. Niacinamide or nicotinamide: Unlike nicotinic acid, niacinamide doesn’t lower cholesterol. However, it may help treat psoriasis and reduce your risk of non-melanoma skin cancer. My organic chemistry is a little rusty but I think I've bought the wrong ones. I got some H&B Niacin (vitamin B3) which when reading the small print is Niacinamide based - no good according to the paper in the video. I need to get some 'pure' Nicotinic acid which I'm struggling to find. Please let me know if you locate any. Cheers : D

@RUNDMC1

3 жыл бұрын

Tim Sweeney Amazon or eBay is probably your friend here!

@timsweeney1999

3 жыл бұрын

Just ordered these, they are the correct type... smile.amazon.co.uk/gp/product/B00BM6QEQA/ref=ppx_yo_dt_b_asin_title_o00_s00?ie=UTF8&psc=1

Hi. Great videos. Extremely helpful and hope inducing. In this video do you know if the recommended Niacin dosage of 25mg 4Xpd was per Kg body weight or is that just an adult dose?

@RUNDMC1

3 жыл бұрын

That’s an adult dose to build up to

I focused on Adenosine. It converts to inosine naturally in hypoxic conditions and is helped by Adenosine Deaminase but that enzyme (which is co-located with DPPIV which is a Covid receptor) is easily taken out by Covid. It is the perfect biomarker or messenger for vascular tone modulation but in the absence of Adenosine Deaminase you need to reach hypoxia for the anaerobic conversion to take place. Incidentally DPPIV also caters for (cleaves) Bradykinin and a supercomputer later suggested it could be a Bradykinin storm some months after I published my conclusions. Look up Adenosine Deaminase Deficiency and Severe Combined Immune Deficiency. We differ from other mammals in that our Adenosine Deaminase is co-located with DPPIV. Did I mention DPPIV also an Angiotensin Converting Enzyme?

@shobvious

2 жыл бұрын

Inosine helped me battle morning fatigue.

Great video again, is niacin the same as vitamine B3? Since when i Google it, I will only get this (in NL) also I started low carb carb high vegetable diet and only eat on 3 moments a day, so you intestines that are a big part of the immunesystem, also get some rest during the day. For me this is starting to work. And pacing is also very important.

@RUNDMC1

3 жыл бұрын

Yes - all very important. Yes niacin is vit b3 👍

Hi run, on your diagrams it looks like nicotinamide feeds into atp? Yet I hear what he's saying... that it has to be niacin or nicotinic acid introduced slowly... the flushing is so annoying

Love these videos, thank you! For those of you doing this - are you taking as low a dose of Niacin as Dr Wentzel recommends? My local Holland and Barrett only had 500mg...

@meg2400

3 жыл бұрын

and experiences with flush/no-flush are appreciated too. Dr Tina Peers recommended no-flush so I bought that, but Dr Wentzel says there are side effects with this

@RUNDMC1

3 жыл бұрын

If you don’t get the side effects then don’t worry! You can find 50mg on Amazon, but try chopping the 500s in half and just taking some of the powder, see how you get on

@meg2400

3 жыл бұрын

@@RUNDMC1 Great, thank you very much!

Good work again I'll be getting the stack this week can you recommend if it's safe to take with pregabalin along side the stack? as fatigue and Nero issues are my main problems at rest right now thanks 😊

@RUNDMC1

3 жыл бұрын

Ask your doctor about that, sorry!

Gez. I salute you sir!

@RUNDMC1

3 жыл бұрын

Thanks Edward!

Anyone else tried getting lots of quality sleep and meditating and other forms of brain/body calming as part of your attempt to speed your recovery? I think these are forgotten ingredients in other recovery regimines. I've been watching a lot of good videos (like this series) and reading articles and have come up with a vitamin/mineral regimine (as specified by MCAS and NAD+ research), but those only helped me get back into the incremental, very slow recovery phase (I'm in my first relapse and experienced recovery this way before) instead of a faster recovery mode. Obviously lots of good quality rest could be important to tip the Long Covid internal balance towards reestablishing our normal homeostasis. (Symptom, insomnia) But with all the extra cortisol and other inflammatory hormones and chemicals we get from both the heightened (Symptom:) anxiety caused by Long Covid and the additional stress and anxiety we are getting from out society gone mad (not to mention loss of loved ones), this could also be supporting the new homeostasis of Long covid.

@amira_shmira

3 жыл бұрын

Quality sleep doesn’t come easy to many of us. A symptom is still insomnia regardless of what you take. I can take melatonin and fall asleep relatively quickly but the issue is staying asleep. No amount of rest makes me feel refreshed, regardless.

Gez! I don't know how else to reach you.. What are your thoughts on Ivermectin in long haulers??

@guineatim3566

3 жыл бұрын

See my comment and associated reply immediately following yours. Ivermectin against NF-kappaB.

stress release and niacin !

I love these videos you are doing. I appreciate all this information too. Is it possible that the autoimmune and mast cell.could all just be a genetic mutation one have and some don't have that reacts to Covid 19. Something that can cause chronic illness's in a specific area or to a specific system that like I said Covid is re-activing to? I have eds, mcas and pots and I know there's a genetic mutation that's causing it tho they haven't found it for the hypermobile type. Do you think the real answer is in our dna with the people are are just more seasonable to chronic illness like my own? Before Covid I had A LOT of theories when it comes to genetics and this kinda feels like i could be an over all genetic susceptibility mutation that we've just never seen before. or maybe get something we have seen over and over like those who end up with fibromyalgia and pots after getting sick with a cold or a virus period maybe there is a genetic susceptibility to these issues when the right Gene is activated by a virus? I'd truly love to hear what anyone else has to say about this theory.

It would be good if you did another interview with Dr Wentzel to see how he and his patients are doing now some time has past taking his supplement stack?

@RUNDMC1

3 жыл бұрын

I’m going to be doing a follow up study to see if the improvement is sustained. Dr Wentzel’s patients are still all doing better.

@georgiabruin5966

3 жыл бұрын

I was taking the stack via a lady in contact with Dr wentzel. She blocked and deleted me when I told her the niacin induced a depressive episode in me. The results are therefore skewed! Not taking on board people who have had negative effects from the stack.

Hi, thank you from across the pond for these videos. They’ve given me hope and answers I’m not getting from my doctors. As evidence to support this NAD+ deficiency theory, due to ongoing symptoms 8+ months later my doctors tested my 5-HIAA levels. I had massively elevated levels, which led to a PET scan that thankfully came back normal. The most common reason for elevated 5-HIAA (a serotonin byproduct) is a carcinoid tumor. My doctors are saying my symptoms and cause of elevated 5-HIAA remain a mystery. It seems to me, however, that my test results may provide proof of the COVID affect on the NAD+ tryptophan/serotonin/IDO/5-HIAA to mast cell activation pathway theory. Curious if this tidbit helps any of the doctors with whom you’re speaking?

@RUNDMC1

3 жыл бұрын

I’ll pass it on!

@erocalypse21

3 жыл бұрын

Mae B can you plz help what kind of Dr do I need to see and what questions do I ask for my long hauler symptoms? Plz help

@tinrom9465

3 жыл бұрын

you have to look into this doctor: he has an explanation for the serotonin-syndrome "Farid Jalali MD on twitter : ".One such platelet mediator is serotonin. Plasma serotonin is kept at tightly regulated low levels by storing 95% of body's serotonin in platelet granules Serotonin is uniquely positioned to 𝗮𝗰𝗰𝘂𝗺𝘂𝗹𝗮𝘁𝗲 in COVID19, as it's released copiously and its reuptake is impaired....." "There is clear evidence of plasma serotonin 𝗲𝘅𝗰𝗲𝘀𝘀 in COVID19, with this excess being a result of platelet degranulation, combined with the pulmonary vasculopathy and endothelial dysfunction of COVID19, the same endothelium that is responsible for reuptake of serotonin.""It is paramount to understand the signs of serotonin toxicity, and to recognize that there is 𝗼𝘃𝗲𝗿𝗹𝗮𝗽 between ARDS / sepsis and the signs of serotonin toxicity Distinguishing signs of serotonin toxicity include - Myoclonus - Hyperreflexia - Severe agitation - Diarrhea"and so on

@maeb7157

3 жыл бұрын

@@tinrom9465 thank you so much! Very helpful. I’ll pass in to the docs.

@judymiller5154

3 жыл бұрын

@@erocalypse21 did you find help yet? I just came across covidlonghaulers.com Havent checked them out yet, but the vid said they would list the tests you should get and work with your GP. Wishing you all the best.

There are millions of people worldwide, suffering for decades with post-viral illness (me/cfs). I hope that this information can also be directed to them, as they've had NO HELP so far &, in fact, have been dismissed as having psychiatric illness.

Hi gez, thanks a lot for this research. How many months are you into long covid ? I'm a 6 monther and I have high heart rate on standing/exertion and slight brain fog which seem to persist since past two months. I'm already taking Fish oil, magnesium, b complex tablets. What's the dosage that you'd suggest for niacin ? I'd love to try that and I hope it works for me.

@RUNDMC1

3 жыл бұрын

I’m 9 months in now, it’s no fun. Start at 25mg niacin then build up to 4 times a day according to tolerance of flushing reaction!

@bharathsunnyBlogger

3 жыл бұрын

@@RUNDMC1 did you have higher heart rate issues as well? If yes, did they go away at all?

@RUNDMC1

3 жыл бұрын

Bharath Sunny Yes - definitely had the tachycardia. It’s starting to calm down a bit but I’ve got to be careful with activity as it will still spike

I recently purchased Niacin (inositol Hexanicotinate) 500mg flush free. Is this an acceptable type of Niacin or should switch it out for something else???

@RUNDMC1

3 жыл бұрын

Better to get the flushing type but this will still help

Hi, Have you heard of anyone taking this stack with persistent abdominal pain, recurring fever and joint pain, improving their symptoms? 6 months of enduring with no improvements. Thank you for your much needed guidance in this difficult time.

@RUNDMC1

3 жыл бұрын

Yes - this stack should help. I’ve got a study in my next film which is showing very good results

@frankttom4990

3 жыл бұрын

@@RUNDMC1 Can't wait to see it Gez, keep on the hard work, many of us rely on you!

Thank you so much for your videos Gez. I am still confused as to whether I should be allowing the flush from niacin to take place ie whether it is more effective if the flush happens or whether I should take niacin after meals. I have been taking 50 mg x 3 times a day after meals for about 8 weeks now.

@RUNDMC1

3 жыл бұрын

Hi Alice, the flush isn’t necessary so if you don’t like it, just take it after the meals!

If ongoing sarscov2 infection is present in small intestines , then RNA should be detectable in stool samples. That would give us some insight.

Hi, Your efforts are very much appreciated!!! Dr. Wentzel mentioned a target does of 100mg. Is this once per day? I know recommendation is to build up. I am handling 50 to 70mg 3x a day after meals. Can you point me to an answer?

@RUNDMC1

3 жыл бұрын

Spread throughout the day is good. If you can handle a little more it won’t hurt - what you’re doing sounds good

could long haulers covid be a retrovirus that was activated by getting sars cov 2?

many long haulers have noticed big improvements by taking L-glutathione, and wondering if anyone can comment on if glutathione is related to the NAD+ processes that are being looked at currently?

@marisademore468

Жыл бұрын

The late Dr Konynenberg successfully treated CFS/ME patients with glutathione precursors. Maybe rectifying glutathione levels or NAD levels produces the same outcome of restoring tryptophan? 🤔

Niacin is a precursor, a building block that helps the body to produce NAD+. However, you can take NAD+ itself, orally, via liposomal NAD+. Liposomal NAD+ is simply NAD+ encased in a liposome capsule that protects the NAD+ from being digested in the gut and delivers it to the cells where it is needed to produce energy. Liposomal NAD+ is available on Amazon.

Really appreciate your input and advice re long covid. I share all your videos on the Irish Covid Cases group I belong to. I'm almost 9 months in now, symptoms mainly breath shortness, fatigue, heart racing. 6 months in when cardiac mri diagnosed myocarditis. Taking NAC, Ubiquinol, Zinc, VitD and multivitamin for some time now. Just started Niacin after seeing your video. My question is.. is it safe to take while on low dose beta blocker? I read that niacin can cause low blood pressure. Mine is already very low. Sorry for long post! Thank you!

@RUNDMC1

3 жыл бұрын

Best to ask your doctor on this front - not my place to advise with potential contra-indications, sorry!

@fclinch7fm

3 жыл бұрын

@@RUNDMC1 I understand, thanks for reply! I'll talk to my gp.

When they talk about the tachycardia symptom related to this, can I assume they mean that all of the POTS symptoms fall into that? Low blood pressure, chest pain, the palpitations and orthostatic intolerance? I’m wondering where to draw the line between NAD deficiency and actual POTS

@RUNDMC1

3 жыл бұрын

It’s hard to know isnt it?

@Isabella-ed8mf

3 жыл бұрын

@@RUNDMC1 It seems so. I wish the researches would clarify that sometime soon

any data on what percentage of long-haulers either were taking a prophylactic (eg HCQ, IVM) or were given early out-patient at home treatment? Thanks

@RUNDMC1

3 жыл бұрын

Not much data on that but the figures would be very low

@judymiller5154

3 жыл бұрын

@@RUNDMC1 thanks, that's what I was assuming. After watching the senate hearing, I am saddened and angry over the increased devastation to Americans by the general discrediting of these treatments that could have either stopped or greatly lessened this disease in most cases.

Thanks so much for this. @gez What brand of Niacin are you using ???

@RUNDMC1

2 жыл бұрын

I use Health Leads but it doesn’t matter too much!

@victorianalin5885

2 жыл бұрын

@@RUNDMC1 thanks for response. I’m a case of LC who has only recently realized I’ve had MCAS my entire life and in that sense I’m grateful, finally an explanation for all my allergies and weird symptoms since forever (and I’m 52!). The flushing makes me nervous thinking about it as I’m typical MCAS and tend to react to drugs/food. I’m going to start low and slow. I take Bilastine (H1) daily. Question: Antihistamines don’t counter the flushing? Wishful thinking right? Do you still take H1 and H2 daily???

Is there any research on cannabis for long covid? I have a lot of esophageal pain. Low histamine and supplements are helping, but not completely.

@RUNDMC1

3 жыл бұрын

Try CBD oil

@TM-li6jr

3 жыл бұрын

@@RUNDMC1 thanks! I'm allergic to cbd unfortunately. I break out in hives 😫

Is there a reason why not to supplement nad/nadh directly or additional to niacin? I have tried nadh and it boostered a lot of energy. However i also red that nadh can have contradicted effect if the nad/nadh ratio gets out of range!

@RUNDMC1

2 жыл бұрын

I’ll ask Dr Wentzel about it when I speak with him!

Have you looked into ivermectin to treat long COVID if someone has a live COVID reservoir? I’m a recovered long hauler. Around month 6, I took a 4 day course of ivermectin. I felt a difference after 1 day and all my COVID symptoms were gone on day 2. My health has been 100% since with no further relapses.

@evanmaxwell4649

3 жыл бұрын

Do you mind if I ask what your symptoms were? Brain fog??

@christiebacon904

3 жыл бұрын

@@evanmaxwell4649 sore throat, runny nose, body buzzing, breast pain, pain in previous recovered injury, fatigue, brain fog, shortness of breath, shoulder pain, loss of sense of smell, heightened allergies, high heart beat resembling POTS

@evanmaxwell4649

3 жыл бұрын

Thank you for replying! Where did you get the ivermectin from? OTC? Online? Prescription?

@christiebacon904

3 жыл бұрын

@@evanmaxwell4649 I’m in Canada. I got it through the back channels. I recommend you try with your Dr first.

@abdulrahmanthattarukudybas3530

3 жыл бұрын

How to take ivermectin , I took 12 mg a day . Single dose or double dose? Should I take two doses in the morning and evening? How did You take it ?

So what should we take ? Suppléments and dosage ? Please write it down. I did not get it... Im not a native. Thanks for your help tho 🙏

@ivnbgtv

3 жыл бұрын

Check the description of the previous video

Gez, Dr W doesnt really answer your question re doseage of Niacin. Looking at FB groups, there is quite a range of opinions re what the dose should be. Do you have any idea? 100mg doesnt seem enough to me.

@RUNDMC1

3 жыл бұрын

Try 100mg a day and if you’re not noticing your fatigue lifting (which will be the first sign) then try going up to 200mg

Gez, apologies if this was mentioned and maybe went over my head, but were any of the long haulers in these studies tested and showed NAD+ deficiency, or is there not a simple tests for this?

@RUNDMC1

3 жыл бұрын

There isn’t a simple test unfortunately - however you can study the effect of niacin, which is exactly what I’m doing in my next film 👍

@alisonreed4408

3 жыл бұрын

@@RUNDMC1 Oh I see, thank you. Looking forward to it!

Gez, I'm still catching up on your videos. I've been doing the low-no histamine diet alone for about 5 weeks and sense some subtle improvement. I want to add the supplement list to my toolkit, but I wonder: do you think we need a doctor advising and following us closely or that we're ok to go ahead with the 'stack?' on our own, so to speak? Also, I sometimes have trouble getting my supplements down (new since Covid) - it's like they get stuck in my throat for an annoying while - so, I'd like to figure out which ones I can safely crush up and put in food or consume in variable, more comfortable ways. So, I thought I might need medical guidance on that nuance... (likewise, if you have any tips on that, I welcome them). This video added to my hopefulness today: MANY thanks! P.S. Do you know if they're starting to do some studies to explore preventative treatments - e.g. people with early covid and trying supplementary or anti-inflammatory regimes with control groups to see if the onset can be prevented? Too late for many of us, but just curious if you're aware of such explorations... Wishing you ongoing healing! P.P.S. It sounds like some doctors really think no-flush is adequate and others suggest flushable niacin - do you have an opinion on this one?

@RUNDMC1

3 жыл бұрын

If you tolerate the stack, no problems. Only thing that might cause issues is niacin. Speaking of which, flush is anecdotally more effective than non flush. Re breaking them down - perhaps try eating them with a mouthful of food? They’re usually designed a certain way to be broken down in the stomach so opening a powder capsule etc will affect the way it’s absorbed. And re that research - it’s been talked about but I’m not aware of any of it going on at the moment.

@nicolaholmes2531

3 жыл бұрын

@@RUNDMC1 Thanks so much for your prompt response - and I wish I had the impression that there was much more research going on regarding long Covid!

I have been suffering for a while now, I had an event in August which I thought was either a heart attack or a stroke. It turns out it was a stroke, I am a generally fit and healthy 30+ year old. Since being ill in March I have suffered quite badly with palpitations and dizziness. I am still under investigation at the moment.

@RUNDMC1

3 жыл бұрын

So sorry to hear that. Best of luck in your recovery.

@evophantom

3 жыл бұрын

@@RUNDMC1 cheers :)

Hi there, thanks for your incredible videos, they are such a help when going through this. Can i ask yourself or anyone in the comments, what is a good place to get or a good brand of Nicotnic acid in the UK? I dont wish to get the wrong one. thanks so much

@RUNDMC1

3 жыл бұрын

Amazon!

@horrormadonna666

3 жыл бұрын

@@RUNDMC1 Thanks so much for the reply. i managed to get the Health Leads ones from amazon and started today :-) Would you mind me asking, and i know you're not a Dr and not allowed to recommend too much, but what dosage are people taking, or recommend building up to, my tablets came in 50mg and i dont know what im aiming for. Also how are you feeling in yourself now? thanks so much for everything youre doing

@RUNDMC1

3 жыл бұрын

horrormadonna666 Build up to 100mg/day, take them after meals. I’m improved from where I was but still got a long way to go

@horrormadonna666

3 жыл бұрын

@@RUNDMC1 thanks so much for your help, i'll aim for that then. glad to hear you are improving and i wish you all the best in your recovery. thanks for all you are doing

Has Dr. Ade Wentzel published his paper yet? I have looked for it numerous times but have been unable to find it.

@RUNDMC1

2 жыл бұрын

I’m asking him!

@scsu11iv

2 жыл бұрын

@@RUNDMC1 - thanks!

@RUNDMC1

2 жыл бұрын

@@scsu11iv if you don’t mind sharing your email address I can send it to you

has anyone had a NAD+ IV drip for long covid? and what were the results?

Can I take Sodium Ascorbate instead of Ascorbic Acid?

I've been taking multi vitamin tablet which included 75mg of B3. Not sure if that's enough. So I just ordered a 250mg slow release B3. Will see if that's effective in a few weeks.

@RUNDMC1

3 жыл бұрын

Good plan 👍

I've only found 250mg niacin tablets in my local shop, cant find anything lower dosage. once a day. Would this be ok? I've been taking it for almost 3 weeks now and other than the occasional flush im feeling a little better.

@RUNDMC1

2 жыл бұрын

If you can handle the flush you’ll be ok :)

@PurposefulPorpoise

2 жыл бұрын

@@RUNDMC1 Thank you!

@RUNDMC1 I can’t decipher what is being said at 9m-21s, where the discussion was a large correlation of long haulers had pre-existing conditions. One was “Rheumatoid Arthritis”, and the other was “ATP”? Not sure I understand ATP… didn’t think “ATP” was a pre-existing condition…. Maybe ATP dysfunction? Same at 14m-05s. “Nicotinic Acid blocks the loading bay that prevents the “sump” from tryptophan to Nicotinic Acid Mononucleotide. What’s a “sump”? Can someone translate that sentence for me? Thanks! Wonderful Content.

@RUNDMC1

3 ай бұрын

Atopy, not ATP! (So eczema, hay fever and asthma)

@Boojerella

3 ай бұрын

@@RUNDMC1 thanks so much!

I'm not clear on the comments about exercise. Should we decrease exercise levels while in recovery?

@RUNDMC1

3 жыл бұрын

Abso-100%-lutely

Hey, thanks again for all your hard work and research. On the antibody tests, I like many long haulers tested negative with the Roche test. I believe it tested IGM and IGG however, I recently took a Sarsplex test and my IGA antibodies where nearly 3000, that's 3 times what is needed for a positive and that's 9 months after the initial infection. I have also learned of others getting the same results. Could there be something linked to this type of antibody? My personal feeling is, that the Virus was present in me for the first 4 months as my body invited it in for a party before realising this little bollocks was going to kill me, then decided to deal with it. I have gotten a lot better from month 5/6 however, I now feel like I am dealing with an autoimmune disorder. It's been like a disease of 2 half's, that has not finished yet. First the virus and secondly the autoimmune reaction driven by an overactive immune response and a high antibody count (only IGA) Agian, thanks for everything. In my darkest days, your research and videos give me hope. Take care.

@RUNDMC1

3 жыл бұрын

Hi Andrew - I think a lot of us feel very similar to you, myself included. Interesting re the IgA results!

@andrewbennett8510

3 жыл бұрын

@@RUNDMC1a few people from the Bodypolitic slack group have had the same Sarsplex results with the IGA Antibodies. Most of the other antibody tests don't look at IGA, they focus on IGG and IGM only. My wife who I caught this from has the IGA and also IGM 9 months on. She had a sore throat for 2 days and no other symptoms. Typical lol. I was pretty much using the supplements you have noted in your videos however, I also use CBD and it makes a massive difference. If I can ever help with anything, just let me know. All the best.

@RUNDMC1

3 жыл бұрын

Andrew Bennett No worries - thanks and best of luck with your recovery!

@frankttom4990

3 жыл бұрын

@@andrewbennett8510 What is the main effect you notice with CBD oil? Any set of symptoms that subside? Thanks!

@andrewbennett8510

3 жыл бұрын

@@frankttom4990 hi, I still have a lot of lung burn and muscle pains around my chest and back area along with some debilitating joint pain. I also get a burning sensation in my blood and throughout my body. Dr Paul Garner described this as having chillies in the blood. This is brought on greatly by talking or doing anything physical. I find the CBD relieves this or of you can get the real oil,, it 99% removes all these symptoms. It’s unbelievable. All the best

I have yet to see a doctor with 10% of the information that you've dug up - thanks to you and other researchers, I bring most of the knowledge to my meetings with doctors. And they charge me. Going to have to look at that... ;)

@RUNDMC1

3 жыл бұрын

Thanks Peter! Where are you based?

Hi hope you don't mind me asking a question as i have been living a nightmare since March, I tested negative for Covid in march (results took three weeks to come back then as it had all just kicked off) yet i had most of the symptoms except for the cough. I did have significant GI symptoms in the 2nd and 3rd week! I have not been well since then with constant rotation of symptoms, ranging from headaches, nausea, stomach pain, some insomnia, shortness of breath that comes and goes, the only symptom that i don't have is fatigue. I had an anitbody test done in June which would have been approx 3 months from when i was first ill and that came back negative also. In essence i am sitting on a negative covid test in March and negative antibody test yet i have all these symptoms for almost 10 months now and my question is have you come across people in this situation? Of course like most i am having no joy with my Doctor they only look at immediate symptom you present with

@frankttom4990

3 жыл бұрын

Hello Simon, there are plenty of people like you (tested negative antibodies, yet have lingering symptoms). I reccomend you to watch all the videos from this channel, they give a good understanding of what Long Covid is and lately, even how to treat it! :)

@Sp-mv5ki

3 жыл бұрын

@@frankttom4990 Thanks Frank i have watched most of them and they are hugely helpful, and also have started on some of the vitamins recommended!! I just wandered if there were people who had both a negative covid test and a negative antibody test as it leaves you in limbo

@frankttom4990

3 жыл бұрын

@@Sp-mv5ki Personally I've seen this case in my country many many times, especially with those who got the virus in the first wave of March, so you're not alone!

@Sp-mv5ki

3 жыл бұрын

@@frankttom4990 Many Thanks Frank certainly helps to know that

I have a NAD+ supplement made by Life Extension. So, I could take that instead of the stack? P.S. Your videos are a huge help! Thanks.

@RUNDMC1

3 жыл бұрын

I would still definitely take Niacin and Zinc

@alisonhoward6665

3 жыл бұрын

@@RUNDMC1 what dose of niacin and zinc?

@RUNDMC1

3 жыл бұрын

Alison Howard start at 25mg of niacin and build up. Zinc is 15-30mg

@krg9942

3 жыл бұрын

@@RUNDMC1 I looked at the ingredient in the LE product, it's Nicotinamide Riboside 100 mg. Will that work?

@alisonhoward6665

3 жыл бұрын

@@RUNDMC1 thank you!

Thank you again for your help and advice. How are you feeling today? Do you feel with the regimental treatment you are taking that you're on the right path to long-covid recovery?

@RUNDMC1

3 жыл бұрын

I do feel better and have more energy - fewer of the wretched symptoms too.

@colinfolan6023

3 жыл бұрын

Good, I'm glad you're feeling better and that the treatment seems to be working for you, that certainly gives me hope as I start the same treatment regime myself.

@frankttom4990

3 жыл бұрын

@@RUNDMC1 Which other lingering symptoms did you have aside from fatigue Gez? I'm interested to know which of mine can subside with this treatment :)

@colinfolan6023

3 жыл бұрын

Out of curiosity, along with the listed supplements you're taking, are you also taking antihistamines?

@RUNDMC1

3 жыл бұрын

Frank T Tom Cognitive issues (brain fog), headaches, skin issues primarily. The fatigue is the worst. Still v exercise intolerant.

I wonder how long after recovery will we have to take niacin for? Thanks again RUN DMC 😁👍

@RUNDMC1

3 жыл бұрын

We should be able to stagger down to a relatively low level

Thank you, Gez, for another fantastic report (I agree with those who've said you deserve official recognition for your work - and, yes, a knighthood would be appropriate :-)). In light of this information on NAD+, I'm thinking that a combination of physical rest and reducing my stress/anxiety was key to the significant long-covid improvements I started noticing around the 5-month mark (Dr. Google confirms that stress really sabotages NAD+ levels). I have an exercise-related question, either for you or anyone else who's inspired to answer. I've been back to exercising since August (initial infection was March), working on returning to my pre-covid fitness level. Recently (i.e. over the past couple of weeks), I re-introduced some fairly hardcore interval training (I also had a couple of unavoidably sleep-disturbed nights). And .... wham. Moderate relapse. I'm not suffering the way I was in the summer, but I'm abnormally fatigued and dealing with some joint pain. I've started taking niacin (just 50 mg/day for the past 3 days, but I'll be increasing - apple pectin seems to be keep the flush away). But now I'm wondering ... Should I be going back to NO exercise? I seemed to be tolerating it well before the high-intensity stuff (and bad sleeps). Or should I just avoid that stuff ... and, if so, for how long? I'm curious about Dr. Wetzel's comment that he is now back to 3-hour windsurfing sessions, given that he is still taking niacin supplements and thus implicitly hasn't yet returned to his baseline NAD+ level. Many thanks again!

@RUNDMC1

3 жыл бұрын

It does seem we’ve got to be super careful with strenuous exercise in recovery. I would take a week off completely, then start to slowly build it back in at a low level but avoid the interval training. Perhaps do a light interval session in a few weeks as a test but definitely don’t push yourself to exhaustion in that session!

@FreddieonFilm

3 жыл бұрын

@@RUNDMC1 Sounds like a plan, Stan! Thanks! When the time comes, I look forward to hearing about your fitness recovery journey. I'm thinking many of us may *not* be returning to brutal, punishing exercise programs - not because it's physically impossible but, rather, because the longterm health costs are so high.

@mrjean765

3 жыл бұрын

Wow - this is a lot more than I can tolerate after 5 and a half months of Long Covid... have not been able to do any more exercise than simple walking. I used to exercise 5/6 days a week prior to L C - running, weights/gym type, ashtanga yoga - and an avid surfer. Envious that you’ve returned to some form of it already...!

@RUNDMC1

3 жыл бұрын

Mr Jean I’m currently having a PEM attack after walking for 1.5km and daring to jog 100m of it. Seems I’m not as far along as I hoped.

@mrjean765

3 жыл бұрын

@@RUNDMC1 very sorry to hear 😓. It’s hard. Also considering how seriously de-conditioned we all are. I lost about 4/5 Kg... take it easy and thank you again for this amazing work you’re doing. Just started the supplement cocktail you recommend will let you know how it goes. At first I was a bit skeptical about L-C / MCAS link precisely because of the huge list symptoms which made me think it could just claim to be the source of every illness under the sun. But these recent videos about NAD + deficiency are fascinating. If you have time I’d love to hear your thoughts about the insuline issue which I tagged you in, in another comment 😅. It does feel relevant to me... Good luck and thank you again deeply for sharing your research so eloquently.