T Cell Receptor Activation

Now that we know about T and B-cell development, let's learn about T cell receptor activation. Only certain T cells are allowed to differentiate into mature T cells, whether CD4+ or CD8+. How does this work? Let's find out!
Script by Niyati Vachharajani
Select images provided by BioRender.com
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Пікірлер: 73

  • @shreyvarad
    @shreyvaradАй бұрын

    best sci-comm channel. no argument.

  • @tempname8263

    @tempname8263

    Ай бұрын

    I've read that as sitcom... which actually fits as well

  • @shreyvarad

    @shreyvarad

    Ай бұрын

    @@tempname8263 honestly, with how much he shits on anti-science spewing charlatans, it might as well be...

  • @wernwin

    @wernwin

    Ай бұрын

    @@shreyvaradwant some bread with that hot dog

  • @tempname8263

    @tempname8263

    Ай бұрын

    @@wernwin *laugh-track*

  • @hardoise667
    @hardoise667Ай бұрын

    You're one of the few with whom I can allow myself to tell people "No guys, there's good on youtube"

  • @mangogo21
    @mangogo21Ай бұрын

    Hey Professor Dave. I was just wondering at 4:31, your diagram had MHCI binding to CD4 T cells, and MHCII binding to CD8 Tcells. Shouldn't it be the other way around?

  • @donchristie420
    @donchristie420Ай бұрын

    Good job on the script,Niyati😊

  • @universeusa
    @universeusaАй бұрын

    Thanks 🙏 Awesome KZread channel We learn a lot 👌👍

  • @Tyler_Durden987
    @Tyler_Durden987Ай бұрын

    Thank you Niyati Vachharajani

  • @nicholasgardiner9601
    @nicholasgardiner9601Ай бұрын

    Thanks Professor Dave, great elocution.🎉❤

  • @kacemmekni
    @kacemmekniАй бұрын

    good job

  • @DylanMc329
    @DylanMc329Ай бұрын

    Is it possible you could do a video on hiv medicines out there and explain how they work and their effecacy? Symtuza is a brand im interested in learning about.

  • @jamiegallier2106
    @jamiegallier2106Ай бұрын

    Thanks Dave!

  • @brian5663
    @brian5663Ай бұрын

    Dear Dave, thank you for your excellent way of educating the public. I do get a great deal of help from your video and enjoy this kind of learning. I am a new member (study buddy) here. I wonder if I am qualified for early access to the hidden videos in Immunology. I am going to take an exam in a few days...

  • @user-ih4zp1ty7x
    @user-ih4zp1ty7xАй бұрын

    4:29 MHC II binds with CD4+ MHC I binds with CD8+

  • @TheCrossroads312
    @TheCrossroads312Ай бұрын

    FYI the schematic @4:36 has CD4 and CD8 flipped

  • @NuNugirl
    @NuNugirlАй бұрын

    Dave can you please explain the effects on B cells after splenectomy, because I have ITP. Thanks.

  • @shelbyg6342
    @shelbyg6342Ай бұрын

    This is what I study for my job! My company creates CAR T Cell therapies for cancer treatment.

  • @0xoRial
    @0xoRialАй бұрын

    good timing for my immunology exam

  • @donchristie420
    @donchristie420Ай бұрын

    Things going well,Wael (Been trying to find the time to learn more about Lebanon)

  • @pramodsingh7569
    @pramodsingh7569Ай бұрын

    Thanks

  • @anonimusgamingnation1979
    @anonimusgamingnation1979Ай бұрын

    how i get acces to full series i am gonna have an exam on imunobiolgy and you help me a loot with your videos and i am stuck at adapative imunity and i know you have recorded all the videos just curios how to acces them if i become a membre i have acces to them ?

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    Ай бұрын

    i release them on a schedule, you'll get them all

  • @keegan6388
    @keegan6388Ай бұрын

    hey professor farina, are you ever going to cover nuclear + radiation physics? i feel like a general explanation of radiation science in your style would help to dispel a lot of the anti-nuclear rhetoric in north america and europe

  • @behavioranature
    @behavioranatureАй бұрын

    You are an idea machine ❤😂

  • @josemadrid2913
    @josemadrid2913Ай бұрын

    So can the more knowledge about T-cells are able to help in the fight against cancer?

  • @Huebert-zp8uq
    @Huebert-zp8uqАй бұрын

    Do you think you could do a video on positive and negative selection in detail? We covered it in courses but it was one of the more confusing topics. Going through things like the antigen presented during positive and negative selection, AIRE etc. I think it’s a high yield topic that also lets you explain autoimmune a little and how the system can go wrong

  • @desmond3828
    @desmond3828Ай бұрын

    When will you talk about the individual cells?

  • @alexmeredith6923
    @alexmeredith6923Ай бұрын

    good video, by the way have you heard of a creationist called dr jeff tomkins

  • @sbindoctor6414
    @sbindoctor6414Ай бұрын

    Please do a video on Dr. Fatima's videos and/or the Dark Matter doesn't exist conspiracies

  • @noblewatcher5732
    @noblewatcher5732Ай бұрын

    Nice , I'm early.

  • @petelewis7313
    @petelewis7313Ай бұрын

    Please can you do a video on the "science" transcendental meditation presents to support the argument they can stop crime and levitate amounts other things . I am trying to help my friend who is planning on leaving his family and giving them thousands of pounds

  • @defiant4759
    @defiant475913 күн бұрын

    T Cell therapy is being tested to help with Autoimmune diseases like Lupus.

  • @sasvideres2065
    @sasvideres2065Ай бұрын

    My myositis loves this 😅

  • @strasdove6214
    @strasdove6214Ай бұрын

    3'57: CD4 interact with MHC-II and CD8 interact with MHC-i !!!!!!!!!

  • @BK201DarkerThanBlack
    @BK201DarkerThanBlackАй бұрын

    I thought this was a video about Tyrant Cells from Resident Evil at first. Given they are called T-cells in the game. Actual science is pretty enjoyable too. So I stayed anyway.

  • @yeetskeet5924
    @yeetskeet5924Ай бұрын

    3k views in 15 hours? Bro is unappreciated 😢

  • @Hungary_0987
    @Hungary_0987Ай бұрын

    Who thinks about how cool it woulf be being a T-cell?

  • @scorcher64

    @scorcher64

    Ай бұрын

    It would be. On the other hand, I also imagine being a helper T-cell running for my life as I'm being hunted down by HIV wanting to latch onto me 🤣.

  • @skim4264
    @skim42644 күн бұрын

    Biorender?

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    4 күн бұрын

    yeah it's dope

  • @briwood6328
    @briwood6328Ай бұрын

    Unrelated, but what do you think of that US military official saying there are non-human entities on earth he sounds crazy to me, just wondering what you think of him

  • @zaconeil3709

    @zaconeil3709

    Ай бұрын

    Why didn't they say 'aliens' if that's what they meant, as there are billions of 'non-human' entities on Earth. 'Entity' doesn't mean 'intelligent, thinking agent'

  • @briwood6328

    @briwood6328

    Ай бұрын

    @zaconeil3709 I know, but it was just odd how he was saying it

  • @goldenquaarter
    @goldenquaarterАй бұрын

    Is that real?

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    Ай бұрын

    yes

  • @mike-Occslong
    @mike-OccslongАй бұрын

    Can ya do a vid on how i can stop going bald

  • @eliasmindreau1637
    @eliasmindreau163729 күн бұрын

    Please free the new videos to all 😅

  • @livingcodex9878
    @livingcodex9878Ай бұрын

    おはようございます

  • @donchristie420

    @donchristie420

    Ай бұрын

    Good morning to you,as well

  • @waelfadlallah8939

    @waelfadlallah8939

    Ай бұрын

    ​@@donchristie420classic duo

  • @howdydoo9148
    @howdydoo9148Ай бұрын

    Do you believe there is an incompatibility between being religious and being a scientist?

  • @CalebKunath

    @CalebKunath

    Ай бұрын

    Nope keep being religious keep following the science you’ll find the truth within

  • @briannunya2838
    @briannunya2838Ай бұрын

    Way to read a textbook

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    Ай бұрын

    It's a script written by an immunologist. Why so salty?

  • @Nxck2440
    @Nxck2440Ай бұрын

    first

  • @waelfadlallah8939

    @waelfadlallah8939

    Ай бұрын

    Yes you are

  • @donchristie420

    @donchristie420

    Ай бұрын

    First to respond to first

  • @lyndonstachoski3897
    @lyndonstachoski3897Ай бұрын

    Nothing says "I'm deeply indoctrinated", than reading from a text book.

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    Ай бұрын

    Nothing says "I'm allergic to learning" like pretending textbook knowledge must be wrong because you say so.

  • @ponponpatapon9670

    @ponponpatapon9670

    Ай бұрын

    we should all read your text book-the Bible, or maybe Quran-instead, right?

  • @galileog8945

    @galileog8945

    Ай бұрын

    All of you conspiracy theorists seem unable to write a coherent sentence.

  • @lyndonstachoski3897

    @lyndonstachoski3897

    Ай бұрын

    Do expermental injections ( mRNA ) increase/improve Immunity response?

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    Ай бұрын

    They're not experimental, and yes they prime the immune system for antibody generation, which is what vaccines do. Anything else, sweetie?

  • @WensleydaleBrown-wo5rg
    @WensleydaleBrown-wo5rgАй бұрын

    Oh boo, you did so many videos without me. 🫤 well what gives man, where's the Cornucopia?!?!