Synthetic Cannabinoids - Myths Vs Science By Dr Raimondo Bruno

Dr. Raimondo Bruno is an Associate Professor in the School of Medicine at the University of Tasmania. His main research interests include the cognitive consequences of use of medications and illicit drugs; illicit drug market trends; and approaches to reduce the harms associated with substance use. He has active research collaborations with key national research centres in the substance use field and holds conjoint positions at Turning Point Alcohol and Drug Centre, and the National Drug and Alcohol Research Centre, University of New South Wales.
Take-Home Points:
• An important component of natural cannabis is cannabidiol which has protective effects against some of the adverse influences of THC.
• THC binds strongly to CB1 and CB2 but is a partial agonist, whereas the synthetic cannabinoids are typically full agonists.
• Synthetic cannabinoids bring a risk of ​the serotonergic syndrome and some have MAO inhibitory effects.
Full article: psychscenehub.com/video/synth...

Пікірлер: 99

  • @Hawklaxx
    @Hawklaxx4 жыл бұрын

    If cannabis was legal people wouldn’t have to search for highly dangerous alternatives. Smh.

  • @amzino999

    @amzino999

    3 жыл бұрын

    M0llY TeNdieS encouraging people to do heroin, right.

  • @amzino999

    @amzino999

    3 жыл бұрын

    M0llY TeNdieS I know it may feel good. But it will fuck up ur life

  • @waltersobchak7275

    @waltersobchak7275

    3 жыл бұрын

    @M0llY TeNdieS i hate smoking reefer but k2 JWH -018 is better in every way. I got a good idea how about the government to stay the fuck out of grown peoples fucking business if somebody wants to use it they should be able to use it the fuck difference does it make. The government cocksuckers just want to throw somebody in jail

  • @waltersobchak7275

    @waltersobchak7275

    3 жыл бұрын

    @M0llY TeNdieS you’re right at least you’re not an ambulance caller. That’s how everything gets banned. I’m not balls to the wall mind you maybe that’s the reason I never had any adverse reactions. Edit. I’m sorry dude I was answering somebody else on here I got you confused.Another guy was telling me that it was the devils potion it was killing people and everybody was dying from it and it was making people crazy I’m sorry wrong person.

  • @waltersobchak7275

    @waltersobchak7275

    3 жыл бұрын

    @M0llY TeNdieS to be clear I agree with everything you are saying.

  • @weedpot100
    @weedpot100 Жыл бұрын

    Legalize all drugs and end the drug war

  • @THEJWHTHECHINADRUG

    @THEJWHTHECHINADRUG

    Жыл бұрын

    TRUE BUT THE WEED DONT GET THE HIGHY AT ALL THJAT GIVE U THE JWH MY MAN.

  • @tomhunt9174

    @tomhunt9174

    Жыл бұрын

    @@THEJWHTHECHINADRUG 🤣🤣jwhs goated fr

  • @Wiwitt1

    @Wiwitt1

    Жыл бұрын

    @@THEJWHTHECHINADRUG JWH also doesnt give you the high from Fentanyl! So try Fentanyl my dear!!!

  • @d4nkx549

    @d4nkx549

    Ай бұрын

    @@Wiwitt1 They are different drugs bro

  • @Wiwitt1

    @Wiwitt1

    Ай бұрын

    @@d4nkx549 I know xD that's why I wrote that

  • @dr.doppeldecker3832
    @dr.doppeldecker38323 жыл бұрын

    Last week i got some "hash", it looked and felt like good quality blonde hash but had no smell whatsoever. I already was sceptical but i took a bong hit anyway. Bad decision! As i was exhaling i already felt uncomfortably high, it only got worse over the next 5 minutes. My whole body was buzzing so hard i felt numb, i couldnt move anymore sitting on the couch still holding the bong in my hand. My heart wanted to jump out of my chest and i was sweating heavily. My vision got dulled, only a small part of my vision was focused. I had very (!) bad paranoia and thought i was gonna die... these effects lasted for about 20-30 minutes and after one hour i was completely sober again as if i hadn't smoked at all. Worst drug experience of my life!!!

  • @linglingyh

    @linglingyh

    2 жыл бұрын

    just wondering but have you developed any sort of anxiety disorder/panic attacks after smoking that?

  • @dr.doppeldecker3832

    @dr.doppeldecker3832

    2 жыл бұрын

    @@linglingyh no i haven't had long term problems, but I just smoker it once and threw the rest in the trash. But there is a Vice documentary on people addicted to synthetic cannabinoids in the UK, they have bad physical and psychological (like anxiety etc) side effects. If you have a feeling your weed is laced with synthetic cannabinoids don't smoke it, throw it away and delete the dealers number^^

  • @linglingyh

    @linglingyh

    2 жыл бұрын

    @@dr.doppeldecker3832 i was just concerned about the possibility of you having ptsd from that trip. they usually dont get better after an hour lol, it can like peak after 12 hours which is deadly and traumatizing - to start out horrible and just keep getting worse

  • @dr.doppeldecker3832

    @dr.doppeldecker3832

    2 жыл бұрын

    @@linglingyh what has this youth come to.... not every bad situation is traumatizing or PTSD inducing..... Just get over it like everyone else does^^ And why are you even concerned about me? we don't know each other? Be concerned about real people around you and not random people on the internet;)

  • @linglingyh

    @linglingyh

    2 жыл бұрын

    @@dr.doppeldecker3832 because you might end up going 20 years without ever knowing you have ptsd and a single youtube comment (since your experience wasnt bad i shouldnt have bothered - hence the inability to grasp how k2 could induce trauma) could be valuable

  • @SouthAfricanCannabisExtraction
    @SouthAfricanCannabisExtraction2 жыл бұрын

    Enjoyed this discussion.

  • @PsychiatrySimplified

    @PsychiatrySimplified

    2 жыл бұрын

    Thank you for your feedback

  • @LiamPorterFilms
    @LiamPorterFilms3 жыл бұрын

    Very informative and the speaker has a charismatic style. Still, I do not know why he titles it "myths vs science" when he addresses no myths. Perhaps the full talk does?

  • @PsychiatrySimplified

    @PsychiatrySimplified

    3 жыл бұрын

    Here is the other part of the video kzread.info/dash/bejne/dIOqmsmScrPamso.html

  • @leifhansen1723

    @leifhansen1723

    2 жыл бұрын

    Gb,bmh;:;;

  • @sweatington8423
    @sweatington84233 жыл бұрын

    The irony of a country banning the import of water and then later having their forests ablaze is something

  • @ramses2797
    @ramses27972 жыл бұрын

    It's crazy because I'm in California where you can just walk in a store buy whatever strain of weed you want no problems It's a shame that people have to use crap like that..

  • @THEJWHTHECHINADRUG

    @THEJWHTHECHINADRUG

    Жыл бұрын

    THE WEED DONT GET THE HIGHY AT ALL THJAT GIVE U THE JWH MY MAN.

  • @ChristopherGray00

    @ChristopherGray00

    Жыл бұрын

    Not all synthetic cannabinoids are bad, most of the problematic ones are the full agonists intended for recreational use and no studies ran, there are therapeutic selective synthetic cannabinoids being looked into for pain management

  • @trvp_biggucci9226

    @trvp_biggucci9226

    Жыл бұрын

    Cannibanoid Oil is Great I wouldn't lie to you

  • @Wiwitt1

    @Wiwitt1

    Жыл бұрын

    @@THEJWHTHECHINADRUG if you only smoke JWH sure. But not if you only use Weed

  • @nickstruggleseveryday8402
    @nickstruggleseveryday84023 жыл бұрын

    I'm her because idk where to go idk if synthetic are studied I know I battle addiction spice took over all addictions and I would just like to try to spread the word of what this does and my experiences with it to save the next person from trying it...I'm sober but right now but I battle...the seizures I have when I'm off of it drs refuse to help and I kind of understand I'd like to find some scientist or drs that are studying this give them my experiences to get some knowledge about this stuff so the next guy or gal does not go through what I do..any suggestions at all feel free this is a long shot i know

  • @waltersobchak7275

    @waltersobchak7275

    3 жыл бұрын

    Addicted really?? I used it on and off for about three or four years I’ve ever felt addicted to it but then again I don’t really like the feel of smoking reefer so

  • @dll269

    @dll269

    3 жыл бұрын

    @NickStruggles EveryDay Could u help me to answer some questions? Surly, private.

  • @hankscorpio3959

    @hankscorpio3959

    2 жыл бұрын

    @@waltersobchak7275 stick to the real plant

  • @waltersobchak7275

    @waltersobchak7275

    2 жыл бұрын

    @@hankscorpio3959 yeah I don’t like smoking anything really. Inhaling something that is on fire can’t be healthy.

  • @hankscorpio3959

    @hankscorpio3959

    2 жыл бұрын

    @@waltersobchak7275 so just vape it

  • @Alex_Decastro
    @Alex_Decastro2 жыл бұрын

    Im just curious. Did the random guy not receive credit because his identity is unknown, or because the lack of professional education.

  • @Riamoka

    @Riamoka

    2 жыл бұрын

    Wooosh

  • @daveogfans413
    @daveogfans4132 жыл бұрын

    The problem IMO is people selling weed, when it is in reality some synthetic shit. Or dogdy dealers spraying dirt weed with the synthetic stuff to make it more potent. People won't stop smoking weed, so maybe at least make sure that shit is not laced with potentially more harmful stuff. Come on. Shouldn't this be a no-brainer?

  • @Wiwitt1

    @Wiwitt1

    Жыл бұрын

    thats why Weed should be legal all around the world!

  • @peasantpingu6776
    @peasantpingu677623 күн бұрын

    Just come off these as someone whos come off heroin spice was 10x harder

  • @peasantpingu6776

    @peasantpingu6776

    23 күн бұрын

    Now on the streets where I'm from they're aren't synthetic cannabinoids anymore it's nitazines and xylazines dissolved put on leaf

  • @kayumust
    @kayumust3 жыл бұрын

    this is just salvia right ? the herb shamanns use under their tongue no ?

  • @PsychiatrySimplified

    @PsychiatrySimplified

    3 жыл бұрын

    Synthetic cannabinoids act on cannabinoid receptors while salvia is a hallucinogens via serotonin receptor activity. Ayahuasca, DMT etc fall under that category. You can read more about that here psychscenehub.com/psychinsights/psychedelics-and-hallucinogens-in-psychiatry-2/

  • @NoksUndKutten

    @NoksUndKutten

    3 жыл бұрын

    @@PsychiatrySimplified Salvia's effects aren't produced by serotonin receptor activity. Salvia is a selective κ-opioid receptor agonist and and an even stronger dopamine receptor (D2) (partial) agonist. The drugs most people think of, when you say "psychedelic" have actions on the 5-HT2A serotonin receptor, salvia does not.

  • @PsychiatrySimplified

    @PsychiatrySimplified

    3 жыл бұрын

    @@NoksUndKutten thank you ; you are correct. Its main active component is a diterpene named salvinorin A (SA), a potent naturally occurring hallucinogen with a great affinity to the κ opioid receptors and with allosteric modulation of cannabinoid type 1 receptors.

  • @THEJWHTHECHINADRUG

    @THEJWHTHECHINADRUG

    Жыл бұрын

    THE WEED DONT GET THE HIGHY AT ALL THJAT GIVE U THE JWH MY MAN.

  • @Wiwitt1

    @Wiwitt1

    Жыл бұрын

    @@THEJWHTHECHINADRUG how old are you? 11 or 12?

  • @zachocracy
    @zachocracy3 жыл бұрын

    How is this any different than the 4 synthetic cannabinoids used as medicine today (Marinol, etc). They are labeled Schedule 2, even though they are an analog of a Schedule 1 drug. This is illegal according to 2012 Synthetic Drug and Abuse Program. In 2016, the FDA declared all cannabis extracts be Schedule 1. Under Compassionate Care IND, the goverment gives out medical marijuana, which is federally illegal while the NIDA has a monopoly on research grows. To skirt the law like this is not only hypocritical but sickening. *TLDR* it's only legal of the FDA says so

  • @tomhunt9174

    @tomhunt9174

    Жыл бұрын

    well those are not harmful to the body like these new unknown ones which are fucking insane.

  • @porthoel
    @porthoel2 жыл бұрын

    I used to smoke that fake marijuana and one time I hallucinated a Jamaican kid I could see everything about him full braids in his hair and all I don't know what we were talking about but when I turned around I asked my friend where did that little kid go and the next thing I know he says what little kid you were talking like a two-year-old lol I hate that stuff with a passion I wish I never would have tried it it screwed my brain up I have mental problems because of it

  • @PsychiatrySimplified

    @PsychiatrySimplified

    2 жыл бұрын

    Wow that's a serious hallucination. Thanks for sharing

  • @porthoel

    @porthoel

    2 жыл бұрын

    @@PsychiatrySimplified I did feel the mention this kid looked about 15 16 pretty tall for how a 15 or 16-year-old would be but it was just so weird I almost wonder if it wasn't a real person and they were doing that voodoo stuff astral projection that's how real it seemed anyways

  • @realityisdreams5671

    @realityisdreams5671

    Жыл бұрын

    @@porthoel where was you when you smoked? can you explain how the Jamaican appeared out of thin air, what did you talk about

  • @porthoel

    @porthoel

    Жыл бұрын

    @@realityisdreams5671 I was just in the truck hopped out and there he was was going to the truck from the door at my friend's parents house I have no clue what we were talking about but whatever we were talking about must have been a good conversation cuz when he disappeared that's when I turned around to ask him a question I have no clue what I was going to ask him it was so weird

  • @Wiwitt1

    @Wiwitt1

    Жыл бұрын

    I was on that shit for over 6 years. I also wish I'd have never touched it once!!! Its the worst Drug I've ever used, and I was also on Meth.