Stereospecificity vs. Stereoselectivity and Regiospecificity vs. Regioselectivity

Many organic chemistry students think that specificity and selectivity are essentially synonymous when describing the potential products of a chemical reaction. But this is not true! They have separate meanings and imply different things, so let's make sure we know how this works when applied to stereochemistry and regiochemistry.
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Пікірлер: 68

  • @ahmedawad7369
    @ahmedawad73694 жыл бұрын

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    @vreddappareddy34484 жыл бұрын

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    @ryantoth6764 жыл бұрын

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    @ProfessorDaveExplains

    4 жыл бұрын

    That was no dream, buddy!

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    @ryantoth676

    4 жыл бұрын

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    4 жыл бұрын

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    @ChrisReaney4 жыл бұрын

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    @kdss4 жыл бұрын

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  • @dakshir1124
    @dakshir11244 жыл бұрын

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  • @marianhenderson1759
    @marianhenderson17592 жыл бұрын

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    @dikshasingla34144 жыл бұрын

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    @kmarie1102 Жыл бұрын

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    @Omprakash-fd2pc4 жыл бұрын

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    @irenevitali56624 жыл бұрын

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  • @KJoshi2006
    @KJoshi200616 күн бұрын

    Beautiful lecture, thanks prof ❤

  • @starbitna6761
    @starbitna67613 жыл бұрын

    wow it is very clear explanation. Thank you :)

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  • @danielblancoania8194
    @danielblancoania81943 жыл бұрын

    Stereoselectivity/stereoselective: Stereoselectivity is the preferential formation in a of one stereoisomer over another. When the stereoisomers are enantiomers, the phenomenon is called enantioselectivity and is quantitatively expressed by the enantiomer excess; when they are diastereoisomers, it is called diastereoselectivity and is quantitatively expressed by the diastereomer excess. Reactions are termed (100%) stereoselective if the discrimination is complete or partially (%) stereoselective if one product predominates. The discrimination may also be referred to semiquantitatively as high or low stereoselectivity.

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    @gamexpose63014 жыл бұрын

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    3 жыл бұрын

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    @user-jj7gz3oi2s6 ай бұрын

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    @ProfessorDaveExplains

    4 жыл бұрын

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    4 жыл бұрын

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    @user-nz2ul2pz7q3 күн бұрын

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  • @bruskmusked7648
    @bruskmusked76482 жыл бұрын

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    @shivangipal68833 жыл бұрын

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    @rijojohn7218

    Жыл бұрын

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    @toufick3 жыл бұрын

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  • @danielblancoania8194
    @danielblancoania81943 жыл бұрын

    Stereospecificity/stereospecific: (1) A reaction is termed stereospecific if starting materials differing only in their configuration are converted into stereoisomeric products. According to this definition, a stereospecific process is necessarily stereoselective but not all stereoselective processes are stereospecific. Stereospecificity may be total (100%) or partial. The term is also applied to situations where reaction can be performed with only one stereoisomer. For example the exclusive formation of trans-1,2-dibromocyclohexane upon bromination of cyclohexene is a stereospecific process, although the analogous reaction with (E)-cyclohexene has not been performed. (2) The term has also been applied to describe a reaction of very high stereoselectivity, but this usage is unnecessary and is discouraged.

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    @user-th5ne6gq9c2 жыл бұрын

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    @akvs20024 жыл бұрын

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    @kayisire98834 жыл бұрын

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  • @danielblancoania8194
    @danielblancoania81943 жыл бұрын

    Hello. First, I want to say that I like your channel very much (and I can see that this feeling is quite general among people). Secondly, I have to tell you that what you present here is a simplification of the real situation that leads to error. In principle, the term "regiospecific" doesn't exist because it is inconsistent with the definitions of "stereoselective" and "stereospecific". The reaction that you have presented is completely (100%) regioselective, but not regiospecific. I post here the IUPAC definitions:

  • @danielblancoania8194
    @danielblancoania81943 жыл бұрын

    Regioselectivity/regioselective: A regioselective reaction is one in which one direction of bond making or breaking occurs preferentially over all other possible directions. Reactions are termed completely (100%) regioselective if the discrimination is complete, or partially (%), if the product of reaction at one site predominates over the product of reaction at other sites. The discrimination may also semi-quantitatively be referred to as high or low regioselectivity. In the past, the term "regiospecificity" was proposed for 100% regioselectivity. This terminology is not recommended owing to inconsistency with the terms stereoselectivity and stereospecificity

  • @danielblancoania8194
    @danielblancoania81943 жыл бұрын

    I think it's important not to create confusion and not to misuse the well-defined terms. It's only my advice. Cheers, Dani

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    4 жыл бұрын

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    4 жыл бұрын

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    @user-iz7lc3bx9o4 жыл бұрын

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  • @bunny4173
    @bunny41732 жыл бұрын

    BOOKS MENTION "REGIOSELECTIVITY" FOR ALKENES INSTEAD OF "REGIOSPECIFICITY" ?? Any reason for that ?

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    @user-yn3dw1fu5t4 жыл бұрын

    Great

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    @howtoinchemistry85194 жыл бұрын

    Nice

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    @gr0un2054 жыл бұрын

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    @ProfessorDaveExplains

    4 жыл бұрын

    check my modern physics playlist

  • @koen9910
    @koen99108 ай бұрын

    Is it possible voor a reaction to be regiospecefic and stereospecic at the same time?

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    8 ай бұрын

    yep

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    4 жыл бұрын

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