Stereochemistry - R S Configuration & Fischer Projections
This video provides an overview of the stereochemistry of organic compounds and defines what exactly a chiral carbon center is. This video also shows you how to assign R and S configuration to a chirality center whenever the hydrogen (4th group) atom is in the front, back, or neither. It also discusses nomenclature - how to name organic compounds using R and S absolute configuration. It provides a lot of examples and practice problems.
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@realndu
2 жыл бұрын
Thanks Man! Hope to get a like :)
@Curiousviewer23
Жыл бұрын
In minute 17:00 shouldn't there be 9 chiral centers and not just 8. I am referring to the carbon under the second carbon that you numbered. Isn't that also a chiral center since it is attached to 4 different groups?
@macysnatural8144
Жыл бұрын
@@Curiousviewer23 I thought the same too but I just goggled for the structure of cholesterol and he has the wrong structure....the particular c you speak of own the double bond too that was put away
@sammuelboateng282
Жыл бұрын
Thanks man, i don’t usually go to class I learned from you 🙌🙌🙌🙌
@user-tq9pp9xh6u
10 ай бұрын
@@Curiousviewer23 samee!!! Doubt
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@bree8852
3 жыл бұрын
same here! the only reason I've passed ANY of these classes!
@mimiloula4723
2 жыл бұрын
Yeah me 3 God bless him & Guide him 2 His path as he is guiding us 2 chemistry ❤
@courageagbanyo8091
2 жыл бұрын
me 4
@elizabethnjoroge5034
2 жыл бұрын
Me 5🥳
@satyarajshivareddypeta613
2 жыл бұрын
just curious, is this taught in high school or college in your country
Your videos helped me study throughout my bachelor's degree in chemistry . I am currently a Pharmaceutical Technology grad student and i also work part time as an chemistry tutor and i still watch your videos in order to prepare my lesson plans. I have no words to express my gratitude for your help through all these years!
@amdkits
Жыл бұрын
Bro what happened if you take norflox by mistake? I accidentally took one
@p-dawgisaregisteredsexoffe7890
Жыл бұрын
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@amdkits
Жыл бұрын
@Doge to Moon ha bhai jaise taise bach gaya... galti se leliya tha
@hexcoff1689
10 ай бұрын
Same here
Ah,lets learn stereochemistry at 1 AM
@rubenfigueroa1063
3 жыл бұрын
12:34am tonight
@aformula4198
3 жыл бұрын
5:45 Am
@rubenfigueroa1063
3 жыл бұрын
@@greeng6914 good luck soldier, it’s worth it in the end
@icarus5676
2 жыл бұрын
3:10am
@legenarymaster3696
2 жыл бұрын
12:48am
TY, I appreciate all your hard work. I watch many of your videos and they have helped a lot! ***Possible CORRECTION? looks like the cholesterol molecule in your video has the double bond in the wrong place. *** I kept going over and over this and could not understand why Carbon-5 (the one due south of the methyl group) was not a chiral center? As the figure is drawn, it should be...which would make 9 stereocenters, not 8. But when I looked up cholesterol, the double bond is actually between C-5 and C-6 not as you've shown it. Just in case anyone else got stuck on this problem.
@yevheniiavelihina1197
Жыл бұрын
Same for me
@DrTuph
11 ай бұрын
Thanks for this comment. I've been sitting here the past few minutes trying to figure out why there would only be 8 given the drawing in the video. After looking up what cholesterol should look like, it makes sense.
@boatman3132
10 ай бұрын
I have struggled for this question as well until I found out your comment. It seems that there are 2^9=512 different stereoisomers in cholesterol.
@dukeaboagye3099
7 ай бұрын
thanks can't believe I realized it
@pfelixtutor8738
6 ай бұрын
I saw that too, the double bond is in a wrong position. All the same thank you 🙏
17:08, isn't there another chiral center below carbon #2, since first bond goes to a sp3 C, second to sp3 CH2, and third to a sp2 CH and a hydrogen?
@FBWUniverseMode
3 жыл бұрын
yess there are 9 not 8 chiral Cs
@oluwajobipeterpelumi1279
3 жыл бұрын
Brilliant you are correct.. Wanted to ask too
@xeel224109
2 жыл бұрын
Yes, he drew the molecule with the double bond in the wrong place. Cholesterol has 2^8 isomers but the drawn molecule has 2^9.
@n_7458
2 жыл бұрын
He made a small error and drew the double bond in the wrong place. So, you're right that the molecule shown has 9 stereocenters! In reality, cholesterol only has 8. You can confirm this by googling the molecule. xx
@Scifiotica
2 жыл бұрын
@@xeel224109 Oh thanks I thought I had lost it there! Now it makes sense.
you are a unique teacher I have ever faced IN MY LIFE. you are lightening the difficulty of students. keep moving!
the double bond in the cholesterol is incorrect. it needs to be moved one bond to the left. I kept thinking there were 9 chiral centers until I googled it. Keep up the great work!!
@wdzcix
Жыл бұрын
i was so confused on that lol
Another incredible video; thanks so much for posting! If the hydrogen (or lowest priority group) isn't where I want it to be, sometimes I just exchange two groups to make that happen, and remember that that inverts the stereochemistry (R -> S or vice versa).
Would definitely like to see the face behind the man behind my success. The organic chemistry tutor has helped me Ideally with statistics, Calculus, a bit of genetics, general chemistry, Physics and organic chemistry ❤️
@SeanElliottH
2 жыл бұрын
Same
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When identifying the chiral centers on cholesterol, I think you accidently missed one and it would be 9 instead of 8. Isn't there a chiral center on the carbon below the one you indentified as 2?
@XQJimmy
5 ай бұрын
You are right! Based off of his structure, there are 9 chiral centers. However, the double bond in his cholesterol drawing is in the incorrect position; it should be moved one spot to the left. After that change, there will only be 8 chiral centers
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For Q3, the one assigning chiral centers for Cholesterol, would there not be a chiral carbon just below the 2nd chiral carbon? It is attached to a sp2 hybridized carbon, the carbon with a methyl group, and a ch2 carbon that eventually leads to an alcohol
@ayaansurti2876
8 ай бұрын
yes, it is chiral so there are 9 chiral centers
@felipetabareguicheneyvicen68
6 ай бұрын
Yes, he drew the double bond incorrectly, the two cicle hexanes are supposed to be "fused" via a double bond between the carbon under chiral carbon 2 and the carbon to it's right, so in the cholesterol molecule there are only 8 chiral centers, but the molecule shown in the video has 9 chiral centers.
That trick at the end with the triangle and the circled number was mind-boggling haha. That makes it so much easier, thanks!
@maryamshafeeq1423
2 ай бұрын
This is actually difficult, I couldn't understand 😢
Thank you so much. Your explanation is simple and clear
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@TheOrganicChemistryTutor
5 ай бұрын
I'm glad you found it helpful.
@allwasmie
5 ай бұрын
me too im questioning if im even belong in my major anymore until i watched this video XD hope you feel better tho!
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@mrbot9645
3 жыл бұрын
Y cant u religious ppl just say god rather than jesus,shiva,allah
@des00000
3 жыл бұрын
@@mrbot9645 careful, your ignorance is showing
@MayaMaya-xx8qu
3 жыл бұрын
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@AshishJoshi-tj3qs
3 ай бұрын
@@mrbot9645 careful, your ignorance is showing
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I know you probably wont read this, but I want you to know that my Organic Chemistry professor didnt even mention you could just skip over four. She overcomplicated it by making you switch configurations twice, etc...thank you so much.
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The triangle trick was so helpful!!
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@tiernanomahoney3925
Жыл бұрын
You're learning this in university..😱☠
@tanishkchaturvedi8965
Жыл бұрын
its in class 11th in india
@AshishJoshi-tj3qs
3 ай бұрын
@@tanishkchaturvedi8965 don't worry ye sab university me bhi aaega.
The position of the C=C in cholesterol is wrong, according to your drawn diagram, there should be 9 chiral centers, but for cholesterol, there is only 8 because of the positioning of the C=C. But other than that, I loved the video and it helped me a lot in understanding stereochemistry.
You have my respect sir. You just saved my life.
life saving tip at the end of the video guys! Thanks!
This great. Thank you so much.
Thank you! You saved me so much trouble :) Have a nice day!
단순히 유기화합물은 자기 스스로의 상태 예컨대 에테인이라면 에테인의 상태로 메테인이라면 메테인의 상태로 존재하는 줄로만 알았는데 일련의 순환적 과정이 있다는 사실을 이 영상을 통해 깨닫고 깊은 감명을 받았습니다.
@lnfernalGamingYT
3 жыл бұрын
그건 무작위
@esketiterobi8571
3 жыл бұрын
thats how i feel
It litteraly 1 minute you the best
@esketiterobi8571
3 жыл бұрын
now in english pls
That last technique was the best thing in the video!
It was very helpful!!! Thanks
Just king. Best advice to imagine configuration...
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So helpful in understanding Stereochemistry ❤
really nice teachings. I didn't really understanding the last example
Thanks thanks thanks!!! Very helpful
Please do a video on symmetry operations 🙏🏽🙏🏽
I have trusted you with my As and A level Chem and Math classes and Uni here I am😢...you still helpful
I've got a question regarding the Hydrogen Atoms in the Cholesterol Molecule. Did you follow any rules when placing the Hydrogens in between the Carbon structure regarding their position behind or in front of the planes? Or is their position arbitrary? Thank you so much for this great tutorial. It really helps!
@seungminned0922
Жыл бұрын
Can anyone answer this? I wanna know too. Thank you to the one who will answer.
The world best teacher ❤
17:07 Shouldn't the tertiary carbon beneath the one numbered 2 be counted as a chiral center?
@alanc6468
3 жыл бұрын
He drew cholesterol wrong, there should be a double bond there.
@aaliyahnuma4176
3 жыл бұрын
thank you for asking this because i was confused why it wasnt considered as one
@mahdialachyarendriko8893
3 жыл бұрын
he misplaced the double bond,
@princeslime831
2 жыл бұрын
preciate yall fashoski i was very confused
solid video, appreciate it
This video made this topic easy for me thank you sir
For number 3, why is the carbon below the second chiral center NOT a chiral center?
@dontmindme6520
Жыл бұрын
It is one, I think he forgor
Very clear! Thank you!
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at 17:30 there is an another chiral carbon on the left of the double bond
thank you sir from india !!
Thank you so much ✨
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When you explain chiral centers in cholesterol, there is an error in cholesterol at 17:17. The double bond should be on Carbon 5 and 6 not on 6 and 7.
amazing
thank you for simplifying ochem!
In problem 3, why is the tertiary carbon closest to the double bond not considered a chiral center? I am talking about the bottom right carbon on the farthest benzene to the left of the cholesterol.
@quinnparker3863
2 жыл бұрын
I noticed that too, I think he just over looked that one
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Thank you sir