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Sodium-potassium pump | Cells | MCAT | Khan Academy

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How a sodium potassium pump can maintain a voltage gradient across a cell or neuron's membrane. Created by Sal Khan.
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Пікірлер: 162

  • @weebleapplesmooooo
    @weebleapplesmooooo10 жыл бұрын

    POTASSIUM. POTASSIUM. POTASSIUM 9:02 9:41 9:43 10:08 10:18 10:23 not sodium

  • @msokiedokie123

    @msokiedokie123

    10 жыл бұрын

    Good looking out

  • @weebleapplesmooooo

    @weebleapplesmooooo

    10 жыл бұрын

    I am a hardworking man 8-)

  • @zaimahbegum-diamond1660

    @zaimahbegum-diamond1660

    7 жыл бұрын

    Sean Ngui thank you..I picked that up, which means something is making sense. please do a new one Mr Khan.

  • @AA-ge6vo

    @AA-ge6vo

    6 жыл бұрын

    Thank god i am not the only one; I was losing my mind!!!!

  • @MyAdventuresInc

    @MyAdventuresInc

    5 жыл бұрын

    ikr

  • @ffzilla
    @ffzilla6 жыл бұрын

    Despite getting a little confused with the mix up with potassium-sodium, and sodium-phosphate... I found this video so HELPFUL! It was quite simplified and easy to follow. Thank you for your help.

  • @heatherdahlin4737
    @heatherdahlin47379 жыл бұрын

    You mix up your solutes many times. First you say that you pump out 3 phosphorus when you meant sodium and then you say you pump in sodium when you meant potassium. Otherwise, really appreciate the video.

  • @AlanUy212
    @AlanUy21211 жыл бұрын

    I'm learning more on KZread than in school for 2 reasons: 1) Visualization of information in an entertaining manner; and 2) Predisposition to learn (I choose what I'm interested in learning). This is the future of education.

  • @MrTRANnysaurus
    @MrTRANnysaurus10 жыл бұрын

    07:25 Instead of "phosphate groups" it should actually be Na+ that gets pumped to the outside.

  • @onceinalifetime9
    @onceinalifetime912 жыл бұрын

    You are the best! Finally someone who can make sense of physiology and make it understandable. If professors cared enough to teach like you do there wouldn't be a pass or fail. It would be a passed the class only scenario. Thank you. I will be following all of your videos and telling all of my friends and family where they can go for clarity. Thank you. 1,000 times thank you.

  • @BruceWayne-tt5uk
    @BruceWayne-tt5uk8 жыл бұрын

    you said sodium ions in step 5 when it was supposed to be potassium

  • @llee9ful

    @llee9ful

    3 жыл бұрын

    Yes I saw that! i'm not going mad :D

  • @AmyyyCullen
    @AmyyyCullen13 жыл бұрын

    Cheers mate, i'm a year 12 human bio student from Australia, about to do a test on this tomorrow and was so confused up until now. Your fantastic at explaining and i'm going to forward this video on to all my friends as we are all so confused. Thanks man! i really appreciate it :)

  • @mehrgoltiv9723
    @mehrgoltiv972310 жыл бұрын

    These videos are all truly great, but this is the second one in which you have said "sodium" when you actually meant "potassium." Please be more careful!

  • @felicegranados7897

    @felicegranados7897

    10 жыл бұрын

    thats why he made a correction video on it :)

  • @aurelliawhitmore
    @aurelliawhitmore10 жыл бұрын

    He made a few mistakes with naming Na K and K Na. He also called the Na in the second pump he drew to the left Phosphate,but he explained it very well.

  • @WispNL
    @WispNL11 жыл бұрын

    I agree, but for specific reasons. Although a good teacher will explain this equally well, KZread has these benefits: 1) you follow the explanation at a time of your own choosing, 2) there's less to no interference by classmates, 3) you can pause, repeat at will.

  • @chrissweeten846
    @chrissweeten84610 жыл бұрын

    what does he use to make these videos? It looks really fun!!

  • @jamieli9792
    @jamieli979211 жыл бұрын

    Why would i read my biology notes when i can just watch this :D Thanks for making my life easier in biology!

  • @AUSTrepznt
    @AUSTrepznt12 жыл бұрын

    i cant believe how much sense this makes ! your are the best

  • @EDhynh0
    @EDhynh013 жыл бұрын

    @127miles - Yes, there is: Neurosciences. You can graduate in Medicine and then specialize in Neurosciences (like António Damásio did) or you can graduate in Biochemistry and then graduate in Psychology and then you'll be able to study Neurosciences. Actually if you take that second option, you'll understand more of the way the brain works molecularly (bcuz of Biochem) and you'll also understand better the human mind (bcuz of Psychology). My advice is: second option ;)

  • @horsinoff6
    @horsinoff611 жыл бұрын

    This guy explains things better in 14 minutes than my lecturer does in two hours

  • @msmadijoh
    @msmadijoh9 жыл бұрын

    There are so many mistakes said in this video. You should redo it.

  • @robertputneydrake
    @robertputneydrake8 жыл бұрын

    my god frank zappa is alive and teaches about neurons!!

  • @olgaperez6604
    @olgaperez66045 жыл бұрын

    He said sodium instead of potassium and since i hardly understand this i was going to lose my mind until i read the comments

  • @imegatrone
    @imegatrone12 жыл бұрын

    Nice Video How a sodium potassium pump can maintain a voltage gradient across a cell or neuron's membrane That You Share , So Very Nice Thanks You

  • @MakeMEEuP
    @MakeMEEuP12 жыл бұрын

    yes, he said anywhere along the neuron that isnt mylinated. So yes you would find it on axon (nodes)

  • @MichAndo2712
    @MichAndo27128 жыл бұрын

    How many other people gringe when this guy says Sodium as he writes K and Potassium as he writes Na!!

  • @QuangLi

    @QuangLi

    6 жыл бұрын

    Michelle Anderson "gringe"?

  • @KK-fq6sm
    @KK-fq6sm7 жыл бұрын

    To those of you about to fail your tests, I salute you.

  • @marcusmd114
    @marcusmd1149 жыл бұрын

    I actually learned two things. The sodium/potassium pump and how a volt meter works :P Really effective vids man. :)

  • @IamChandEvil
    @IamChandEvil14 жыл бұрын

    yup, its sodium ions that are released outside the cell, and the phosphate is released inside the cell simultaneously =P

  • @remedytheband
    @remedytheband11 жыл бұрын

    Look up Synapses, I think that should give you the general idea. Basically the action potential opens Calcium channels and this leads to Neurotransmitter (or even Hormones maybe?) being released outside the Neurone, converting the Electrical Signal into a Chemical Signal.

  • @SWIFTzTrigger
    @SWIFTzTrigger13 жыл бұрын

    actually in its resting state the potential difference is -100mV (resting membrane potential) this is Veq, or equilibrium voltage, it goes to -70mV when the AP passes this is its driving force (therefore 30mV is the driving force of the AP)

  • @Shacklebolt29
    @Shacklebolt2911 жыл бұрын

    My tutor yayy! Thanks Khanacademy

  • @MrMhassan7
    @MrMhassan712 жыл бұрын

    yeah obviously its a fantastic video and me aswell appreciate this man...i was also confused but now its fine......

  • @jonstewopt
    @jonstewopt12 жыл бұрын

    Crystal clear (except minor errors) - thanks. KZread is 'king marvellous for study!

  • @bbbenita
    @bbbenita14 жыл бұрын

    I LOVE the way you explain this......thank you so much! I would LOVE to take your class.....do you teach in Chicago? LOL have a great day!

  • @BigEdJon
    @BigEdJon11 жыл бұрын

    The Na would be constantly moving around (kinetics) so at some point the Na will combine with the receptor sites. Also the inside of the cell is also positive so the Na ions would still repel even if the inside of the cell is less positive. At least that is my thought/explanation

  • @aidan6123
    @aidan612311 жыл бұрын

    Your videos are fantastic, a great tool for gaining in general biology knowledge

  • @joselesanroman
    @joselesanroman11 жыл бұрын

    Thank you BigEdJon, that makes a bit more sense to me now.

  • @zaidmousa9867
    @zaidmousa986712 жыл бұрын

    Okay. That makes more sense

  • @pranjaliitk
    @pranjaliitk12 жыл бұрын

    AWESOME VIDEO....helped a lot fr my xams!!!

  • @LeanneJenZiegler
    @LeanneJenZiegler3 жыл бұрын

    You made some errors...step 4 is Potassium, not sodium (as you said) and I think you made another error earlier in the video. Can you fix these so your video will make more sense?

  • @MitchumJay
    @MitchumJay10 жыл бұрын

    Thanks! the videos I was watching showed repolarization as only K flowing outside the membrane, bud didn't explain how the k returned inside to polarize the cell again. It's the Na/K pump!

  • @kevinkott9853
    @kevinkott98536 жыл бұрын

    This is explanation of Re-polarization to resting potential

  • @emekachukwu1863
    @emekachukwu18634 жыл бұрын

    Wow this is really great Thanks for the info I understand it now

  • @berni17c
    @berni17c13 жыл бұрын

    @nafizkarim he should really check back to this vid and annotate the mistakes. if it wasnt for u i wudve got mixed up, thx for the corrections :)

  • @Dilkaranjot1994
    @Dilkaranjot199411 жыл бұрын

    You mixed up your sodiums, and potassiums a little bit but great video, very helpful!

  • @cherylpops2719
    @cherylpops27198 жыл бұрын

    too many mix ups.

  • @Jamgrah
    @Jamgrah11 жыл бұрын

    Previous Video on this series: Anatomy of a Neuron Next Video on this series: Electrotonic and Action Potentials

  • @sharedivinelove
    @sharedivinelove13 жыл бұрын

    Thanks.. Its a great help. God bless u!

  • @digiconvalley
    @digiconvalley12 жыл бұрын

    thanku veryy much sir.. God Bless you

  • @artanshkoza6741
    @artanshkoza67419 жыл бұрын

    if you say that the main reason of negative resting potential is the high resting permeability of K+, what happens when K+ in the blood goes high? As I know, the K+ might even enter the cell but it (the cell) becomes less positive, but still remains negative, for example at - 60 or - 55 mV. how to explain this negativity in this case?

  • @TheLovelySabrinaM
    @TheLovelySabrinaM11 жыл бұрын

    You're a genius.

  • @ziathegreat
    @ziathegreat Жыл бұрын

    Khan academy is awesome 👍

  • @Momothebean
    @Momothebean9 жыл бұрын

    these videos are great! thanks for the lesson i feel like i understand more now!

  • @leehailey3479
    @leehailey34796 жыл бұрын

    This video was super helpful, thank you!

  • @jennastroup8474
    @jennastroup847411 жыл бұрын

    that awkward moment when you realize that You Tube is more useful than school...

  • @SmashBrosBrawl
    @SmashBrosBrawl12 жыл бұрын

    i love all the pretty colors

  • @shalumaya
    @shalumaya10 жыл бұрын

    sir,the video is very useful in understanding about the sodium potassium pump.But there is 1 mistake in recording,when you explain about two potassium ion by mistake you say that these are sodium ions,overall the video was good.

  • @RoryMajule
    @RoryMajule11 жыл бұрын

    Khan Academy has only been up since 2006, and it already has 3518 videos on KZread, that's almost 1.5 videos a DAY. How does one man learn this much!

  • @bluesoulionj.e424
    @bluesoulionj.e42411 жыл бұрын

    I really appreciate uploading this video! It is really helpful for my biology test!! Really, thank you soooooo much!

  • @moeghoul7444
    @moeghoul74448 жыл бұрын

    u said the phosphates are pumped outside it's the sodium

  • @anooogy
    @anooogy14 жыл бұрын

    saal keeeeeep it up.. ur a gr8 teacher

  • @suprslkchk
    @suprslkchk13 жыл бұрын

    Brilliant...Thanks!

  • @chinchillamdgamer
    @chinchillamdgamer14 жыл бұрын

    @nafizkarim poor guy he kinda just got a bit unattentive for a sec you guys , he was making it on purpose to see if you were paying attention,LOL, the videos are AWESOMEEE :D i love the one of the krebs cycle.

  • @digiconvalley
    @digiconvalley11 жыл бұрын

    thanks alot Sir ! God bless u

  • @Herb19tyt
    @Herb19tyt12 жыл бұрын

    thanks for the video

  • @koerdo1
    @koerdo114 жыл бұрын

    I love your videos but could you please make an video about biological membranes relating carrier proteins, channel proteins, diffusion etc. thank you !

  • @abhinavashok6291
    @abhinavashok62916 жыл бұрын

    Please be careful and attentive. Don't teach the wrong things to people.

  • @Marahxtb
    @Marahxtb12 жыл бұрын

    Thanks a lot!!!! You're awesome!!!!!!

  • @paulinaduarteable
    @paulinaduarteable9 жыл бұрын

    Hi! Can you describe a simple experiment, explaining the contribution of the pump to the membrane potential?

  • @ed-od9sd
    @ed-od9sd11 жыл бұрын

    i have one question, along the path of the neuron, how/where is electrical signal related to chemical signal ?

  • @oooKRISp
    @oooKRISp12 жыл бұрын

    Step 4: He states that we have 2 Na+ ions bonding, but he writes down 2 K+ bonding...

  • @Stonymypony
    @Stonymypony11 жыл бұрын

    So the signal is received at the dendrite right? Does this electrical potential gradient exist from the tip of the dendrites, through the soma (cell membrane), down the axon and to the axon terminals? I thought that the gradient only existed on the axon and the signal traveled down the axon when the signal gets to the axon hillock. Maybe I am missing something...can someone help?

  • @angelipskiss
    @angelipskiss12 жыл бұрын

    Awesome job explaining

  • @sahar1usa
    @sahar1usa13 жыл бұрын

    i think there is also another error at the beginning, Dentrites is not a sender is a reciever !!

  • @marvelboy1974
    @marvelboy197411 жыл бұрын

    I LOVE this man!

  • @chaitanyakeerthi74
    @chaitanyakeerthi748 жыл бұрын

    you told that there are 2 potassium ions passed into the neuron so does the no. of potassium ions inside the cell remain less throughout our life? please answer my doubt

  • @eliotwilliams4480
    @eliotwilliams44803 жыл бұрын

    what does it mean to have a negative voltage?

  • @ausenttalentagency
    @ausenttalentagency14 жыл бұрын

    thank you

  • @FLBandGeek101
    @FLBandGeek10113 жыл бұрын

    do you have anything else on active transport????

  • @joselesanroman
    @joselesanroman11 жыл бұрын

    Why would the Sodium ions want to bind to the receptor site of the (orange) protein in first place if the inside is less positive? Positive-Positive are not attracted to each other. Someone please answer that. Thank you very much.

  • @AlexanderArndt
    @AlexanderArndt9 жыл бұрын

    What happens to a cell if Thallium (TI) binds on it instead of potassium? (It's known that TI got a higher affinity to the cell than K+) The cell gets bigger and bigger but I don't know why...captain!

  • @hedonism13
    @hedonism1313 жыл бұрын

    Everytime he says "cell", I hear it as "Sal".

  • @damarcojohnson3346
    @damarcojohnson33469 жыл бұрын

    Great Job! Love your vidoes!

  • @209yangyang
    @209yangyang10 жыл бұрын

    still a little confuse. what occurs during the resting state ( such as specific ions inside and outside the neuron) i know that part, but what is the voltage inside the neuron during the resting state?

  • @fisslewine1222
    @fisslewine12227 жыл бұрын

    But, doesnt a neuron actually hold data other than the superposition of the stimulation waves? how is that data such as a memory of how to carryout an action stored and stimukated when in need of carrying out the action?

  • @sabrinsawaid8335

    @sabrinsawaid8335

    6 жыл бұрын

    Fissle Wine sorry im late. but the reason why a neruon does not carry memory or any genetic material is because it does not synthesis tRNA so it can not go through the DNA replication process.

  • @ANu-dw9io
    @ANu-dw9io4 жыл бұрын

    What are the things that affect the na/k pump activity?.. Today my exam😓

  • @alissabrougham7440
    @alissabrougham744010 жыл бұрын

    First of, thank you for all the awesome videos! I had a question though, it resting potential -70mv or is it 90mv, or is it between the two?

  • @ChuuliviaHye
    @ChuuliviaHye11 жыл бұрын

    Thabk you so much omg

  • @carlosmerino2243
    @carlosmerino224311 жыл бұрын

    Would this be classified as resting potential?

  • @xdatgrlx
    @xdatgrlx11 жыл бұрын

    Sad but so true!

  • @makeye
    @makeye6 жыл бұрын

    So ATP is not required to change the protein back to its original shape?

  • @carsonwillfixyou
    @carsonwillfixyou10 жыл бұрын

    AWESOME video!!

  • @VXDRG
    @VXDRG10 жыл бұрын

    yeah the sodium and potassium are backwards at times

  • @MelissaSusan1997
    @MelissaSusan199711 жыл бұрын

    @ 9:04 we have 2 POTASSIUM not sodium ions bond to the "pump"

  • @TheSilverMoonFly
    @TheSilverMoonFly11 жыл бұрын

    That's what I was thinking.

  • @freeman8201
    @freeman820112 жыл бұрын

    yes

  • @caesar619
    @caesar61912 жыл бұрын

    When does ADP dissociate from the pump?

  • @RlceBowl
    @RlceBowl11 жыл бұрын

    YOU KEEP MIXING UP K AND NA!!! hopefully most of us caught it beforhand!

  • @v-xup6
    @v-xup613 жыл бұрын

    what program do you use to draw all that, it's such an interesting program.

  • @PV10008
    @PV1000811 жыл бұрын

    i love you mr khan

  • @LSI_MGA
    @LSI_MGA10 жыл бұрын

    Help!!!!!! Does the Na+\K+ pump works during the action potential or only at rest?

  • @Terszel
    @Terszel11 жыл бұрын

    Lol he kept calling the potassium ions sodium

  • @sohanjadhav7816
    @sohanjadhav781610 жыл бұрын

    Good vid