Metabolic Fuel & Starvation

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My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
Opinions are entirely my own.

Пікірлер: 91

  • @DirtyMedicine
    @DirtyMedicine5 жыл бұрын

    Errata: protein is 4 kcal/gram

  • @ejch8456

    @ejch8456

    4 жыл бұрын

    Carb= 4 letters Prot= 4 letters Fatty acid= 9 letters

  • @thephantomfx

    @thephantomfx

    4 жыл бұрын

    whey = 4 letters = protein

  • @thephantomfx

    @thephantomfx

    4 жыл бұрын

    1 g alcohol = 7 grams = 7 letters

  • @fromahappy5536

    @fromahappy5536

    3 жыл бұрын

    @@thephantomfx you came through again man

  • @pyrexcookin

    @pyrexcookin

    3 жыл бұрын

    @@thephantomfx "1g alcohol" contains 8 letters smh

  • @KessaWitdaFro
    @KessaWitdaFro4 жыл бұрын

    "the body only has fat stores for up to one week" *looks down at own gut* 🤔🤔🤔

  • @theclassroomdoc

    @theclassroomdoc

    3 жыл бұрын

    Ya I was thinking the same thing... obviously the body keeps using fats and starts using proteins at the same time...

  • @gwerjio83

    @gwerjio83

    2 жыл бұрын

    @@theclassroomdoc no it doesn't, it will keep using fat as long as the reserves last. The video is complete bullshit

  • @tiffanymegwa7627
    @tiffanymegwa76274 жыл бұрын

    Correction: Regarding PROTEIN it is 1g to 4kcals. Alcohol is 1g to 7kcals. AMAZING VIDEOS regardless! First Aid is the resource

  • @maiaethelkittyheart1
    @maiaethelkittyheart13 жыл бұрын

    Love this! Was so clear and helpful. Wish my lecturers taught like this.

  • @Jameela201
    @Jameela201 Жыл бұрын

    This is amazing! Thank you so much Dirty!❤

  • @daysibeman877
    @daysibeman8772 жыл бұрын

    Best teaching channel for a Medical Student and for also the USMLE. Brilliant teaching

  • @shahrukhbaig2010
    @shahrukhbaig20103 жыл бұрын

    Thanks for your contribution!

  • @Justmyopinionlol
    @Justmyopinionlol3 жыл бұрын

    you just won a subscription with these genius level mnemonics!

  • @carnivorehippie8071
    @carnivorehippie8071 Жыл бұрын

    This is only really accurate within a human organism that is 1) carbohydrate dominant in diet, and 2) does not have sufficient adiposity to sustain mitochondrial ATP production. Although this will undoubtedly help one pass the tests.

  • @monzilachowdhury6590
    @monzilachowdhury65902 жыл бұрын

    I am so grateful for your Biochemistry series. You are the best !! Thank you :)

  • @il3354
    @il33542 жыл бұрын

    Bro, you probably hear this all the time but you’re amazing and you’re doing God’s work 🙌🏼

  • @demmefrazier6629
    @demmefrazier66294 жыл бұрын

    This is so good, you teach how I learn lol!

  • @paulastafford1642
    @paulastafford1642 Жыл бұрын

    That was fantastic! Thank you. ❤️

  • @erinnolte5833
    @erinnolte5833 Жыл бұрын

    Noooo I got a question wrong on UWorld because I didn't read the comments to see the correction that protein was 4! Lol, at least now I will DEFINITELY remember for test day.

  • @crimzonart1269
    @crimzonart12694 жыл бұрын

    Brilliant work

  • @reallyjoewillyoutdoors
    @reallyjoewillyoutdoors3 жыл бұрын

    Great video! 1 small correction - First Aid 2021 has protein as 4 kcal per gram (as opposed to 7 as shown in the video). Ethanol has 7 kcal per gram (7 letters in "ethanol").

  • @DirtyMedicine

    @DirtyMedicine

    3 жыл бұрын

    Yea

  • @yeahrightkashi
    @yeahrightkashi5 жыл бұрын

    Thank you so much!!!

  • @sohailmusawar
    @sohailmusawar4 жыл бұрын

    Superb very well explained Thanks.

  • @anagrocha92
    @anagrocha922 жыл бұрын

    thank you so muuuchhh you made biochemistry easy !!!

  • 4 жыл бұрын

    Brain save the glucose for RBC during starvation by using Keton bodies

  • @theclassroomdoc
    @theclassroomdoc3 жыл бұрын

    Amazing!!!

  • @user-sb1ku5hq7h
    @user-sb1ku5hq7h7 ай бұрын

    Hey, huge love from Russia, we love your channel 🎉 ❤

  • @mintgreen8396
    @mintgreen83962 жыл бұрын

    Thank you! I enjoyed this :D

  • @ajabisong
    @ajabisong4 ай бұрын

    Another beautiful video!

  • @lilmamasofly9111
    @lilmamasofly91114 жыл бұрын

    Thank you

  • @AzharIMGS
    @AzharIMGS2 жыл бұрын

    Excellent

  • @MohamedAli-bk6vk
    @MohamedAli-bk6vk4 жыл бұрын

    Awesome

  • @Sam_1964
    @Sam_19642 жыл бұрын

    Outstanding teacher

  • @1412Z
    @1412Z11 ай бұрын

    Thanks!

  • @zpto12345
    @zpto123458 ай бұрын

    You are THE BEST

  • @kayallen7603
    @kayallen76032 ай бұрын

    This is where this series should begin. This is how your body uses the food you eat to produce the energy to that keeps you alive. Sugar/starches, fats (lipids), and finally (if it needs to go that far) proteins.

  • @debigdogk9563
    @debigdogk956311 ай бұрын

    Awesome video and teaching from GOATT ( Greatest Of All time Teacher ) ❤❤❤❤❤

  • @user-df8ft3km6u
    @user-df8ft3km6u9 ай бұрын

    Omg thank u so much for this

  • @BilgeBegumEr
    @BilgeBegumEr5 ай бұрын

    This is a great video! But, brain is actually highly dependant on glucose, but after 3-7 days, since there is no glucose and the primary energy source is fatty acids, the body starts generating more ketones since brain cannot utilise free fatty acids. This is why it’s highly dependent on ketones, but doesn’t mean that it is always dependent on ketones. I wanted to clarify this :) Thank you very much for your time and thank you for this great video.

  • @centralperk7062

    @centralperk7062

    9 күн бұрын

    Red blood cells can't utilise ketone

  • @sampathr2
    @sampathr24 жыл бұрын

    Your explanation is crystal clear for a layman like me. Tks

  • @drswetaruparel
    @drswetaruparel4 жыл бұрын

    Very helpful videos !!! 👍

  • @izzflipsthetable2715
    @izzflipsthetable27153 жыл бұрын

    Why are ketone bodies not involved in the graph of metabolic fuel utilization? I mean what is the timeline for KB? Wouldn't ketogenesis occur in the liver during prolonged starvation and then break down to get acetyl Coa which enters TCA cycle to provide ATP ? The use of ketone bodies will reduce the use of amino acids for gluconeogenesis, hence preserving protein for survival.

  • @shawnmulberry774

    @shawnmulberry774

    2 жыл бұрын

    The TCA cycle essentially stops if you are truly Keto because you have low glucose and your body will use up resources until TCA can't run. Then it directs Acetyl-CoA down the ketone production line. That takes a little time which is why you tend to go through that "Keto flu" on day 2-3. Once you are burning fat (which he claims here is at 3 days) then you should be eating a diet that is +70% fat. No sugar and very low carbs will keep the TCA cycle starved and ketone production up. This video is about starving so he goes from ketosis to the next phase; breakdown of your body which might happen to an anorexic/bulimic person. That is beyond the stage of ketosis. What we do on Keto diet is enter ketosis after about 3 days and maintain it by eating high fat diet. Too much protein will actually turn up gluconeogenesis and then kick you out of ketosis. Common mistake keto dieters make is too much protein. Obviously you don't want too little so this is why that tends to happen. People recommend different daily amounts of protein depending on exercise, age, size ect. You have to figure out your own number. The graph he shows is labeled Fat or fatty acid. Those are the precursors to ketones. Maybe that is part of the confusion but the graph is showing stores and what you use up as time goes on through starvation. The red line is fatty acids which break down into ketones. Once the fat is all gone you start breaking down your own organs. So you never want to run out of fat completely. I went Keto and went from obese to normal in 4 months. I eat sugary stuff 4 times per year, no grains. Fresh veggies and meat (preferably fish) but no potatoes. Look up Keto / IF

  • @GBOAC

    @GBOAC

    Жыл бұрын

    Because ketones are just a different pathway to use FFA for fuel?

  • @depressedsoul849
    @depressedsoul849 Жыл бұрын

    God bless you

  • @edwinthomasr
    @edwinthomasr Жыл бұрын

    "After one week you no longer have lipid stores" ....laughs in morbid obesity....

  • @lisahamilton8843
    @lisahamilton88432 жыл бұрын

    Sooooo F. Good. I love you X Thankyou

  • @faizazafar5701
    @faizazafar57013 жыл бұрын

    I have never been so fast In subscribing any channel 😅

  • @darinization
    @darinization4 жыл бұрын

    Be careful not to select lactate as a substrate used for energy for the brain. Brain only uses glucose or ketone bodies. So if glut 1 deff is present ketones will provide the energy as lactate and alanine converting to glucose cannot be used. I was confused on this at first.

  • @shotdoctor5869

    @shotdoctor5869

    3 жыл бұрын

    Can you explain what you mean by this?

  • @darinization

    @darinization

    3 жыл бұрын

    TheShot Doctorr the BLaH mnemonic where brain relies on lactate and alanine really means brains relies on liver to convert lactate and alanine to pyruvate and glucose. BRAIN then uses glucose as energy source for days 1-3. I came across a question asking for fuel source of brain that had glucose and lactate as answer choices and remembered “brain relies on lactate and alanine” I got it wrong because brain can only utilize glucose and ketones. LIVER converts lactate and alanine to glucose

  • @williamthurman9082
    @williamthurman9082 Жыл бұрын

    What if u were 100 lbs Overweight??

  • @stephaniemendoza947
    @stephaniemendoza9473 жыл бұрын

    looks at belly :0...."so starve myself for atleast 3 days" :0

  • @lufasumafalu5069
    @lufasumafalu50692 жыл бұрын

    wait a person with lot of body fat will only burn the fat for few days beforr body start using protein ?

  • @gwerjio83

    @gwerjio83

    2 жыл бұрын

    no, they will keep using their fat reserves as long as they last, this video is complete nonsense

  • @edoc431
    @edoc4312 жыл бұрын

    how? This makes no sense if you a lot of fat you're not gonna break down proteins

  • @Cubemaster
    @Cubemaster2 ай бұрын

    For some reason I found myself wanting to try this out - go 3 days without eating so I could say I have no glycogen left and am running solely on beta oxidation. But then I got to the part of the video where you said at 1 week you literally start dying, and I changed my mind 😂

  • @angelamarierose4369
    @angelamarierose43692 жыл бұрын

    I wish I saw this video before I did my metabolism essay

  • @l.gregory3866
    @l.gregory3866Ай бұрын

    7 is ROH, right?

  • @hmmm0o0
    @hmmm0o05 жыл бұрын

    What do RBCs use for energy in a state of starvation ?

  • @whitelion124

    @whitelion124

    4 жыл бұрын

    They still use glucose.

  • @Auguste10

    @Auguste10

    3 жыл бұрын

    and only glucose

  • @theclassroomdoc

    @theclassroomdoc

    3 жыл бұрын

    They get their glucose from gluconeogenesis (making it in the liver). The glucose can be made from fats (they have a sugar backbone) and other ways...

  • @DrRomaMD

    @DrRomaMD

    Жыл бұрын

    Rbcs can work under anaerobic glycolysis

  • @udennaebii1585
    @udennaebii15852 жыл бұрын

    It’s the mnemonic for me 👌🏽👌🏽👌🏽👌🏽

  • @rustymorning431
    @rustymorning4314 жыл бұрын

    So what happened to the guy who fasted more than a year?

  • @iamlocs4737

    @iamlocs4737

    4 жыл бұрын

    Final Crossing exactly and years and years of researching on prolonged fasting. That makes no sense.

  • @adamgordon-strong9055
    @adamgordon-strong9055 Жыл бұрын

    The 7 day absolute Doesn’t make???

  • @Mo-ez3hs
    @Mo-ez3hs3 жыл бұрын

    best channel

  • @marjoriebulusan2132
    @marjoriebulusan213210 ай бұрын

    🎉

  • @shotdoctor5869
    @shotdoctor58693 жыл бұрын

    Shoot, I wish I could deplete my fat stores in 1 week ¯\_(ツ)_/¯

  • @gingernightmare9152
    @gingernightmare91522 жыл бұрын

    Skip to 10.05 to see 1 to 3 days.

  • @alexanderohanlon8825
    @alexanderohanlon8825 Жыл бұрын

    I'd like to meet the individual in the Western world who's FFA stores are depleted in 1 wk.

  • @iamlocs4737
    @iamlocs47374 жыл бұрын

    How do you explain people doing 30 day fast “no food” if after one week your body doesn’t use fat anymore? It does not make any sense when there is so much research that shows that literally your body never kills itself. I can’t believe you are saying this to people without consideration of all doctors research and people doing their own personal experiments and research and they all show that the body heals itself.

  • @JU1CEEY

    @JU1CEEY

    4 жыл бұрын

    I Am Locs when you get to the USMLE exam right.... type your own answer choice.

  • @karlbech1698

    @karlbech1698

    4 жыл бұрын

    yea, i did 18 day fast and pretty sure i did not die or lose much muscle

  • @gwerjio83

    @gwerjio83

    2 жыл бұрын

    you are right, the video is complete nonsense, the body will keep using fats as long as fat reserves last.

  • @kayallen7603
    @kayallen76036 ай бұрын

    It's easy, peasy - really.

  • @n-acetylcysteine8093
    @n-acetylcysteine80933 жыл бұрын

    You are boss

  • @YourFunGazebo
    @YourFunGazebo4 жыл бұрын

    Ubr awsome n u ned a shoutout sir

  • @padmajahawaldar4319
    @padmajahawaldar43195 ай бұрын

    Love u dirty ❤️

  • @mo-LusLAD-hx4ik
    @mo-LusLAD-hx4ik3 ай бұрын

    blahhhhh i am hungry

  • @9907007013
    @990700701311 ай бұрын

    If I have diabetic and Grade 2 fatty liver. How long glycogenolysis will extend??

  • @lillianotuokwu7876
    @lillianotuokwu7876Ай бұрын

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