I have been using 0.25% tretinoin since my early 20’s. Originally it was for PCOS-caused acne. It sorted out the lesions and clogging pretty damn quick and I stuck with it - AND sunscreen of course. I’m in my 50’s now and apart from my pregnancies, I have used it every day. My complexion is much firmer and clearer than most women my age and basically, they’re going to have to tear it from my cold, dead claws when I’m dead.

@jenA9026

6 ай бұрын

😂

@rics1883

6 ай бұрын

Do you get compliments for your skin?

@sarakim1070

6 ай бұрын

I love this comment so much 😂

@katieprice8076

6 ай бұрын

🎉🎉 Do you mean .025 or .25?

@childoftheocean_

6 ай бұрын

Did you notice a difference in wrinkles?

Michelle: "Guys, *STOP* bullying hyaluronic acid 😡😡😡 they are a *good* little active ingredient and they're trying their best and I am *proud* of them 😡😡😡😡"

@LabMuffinBeautyScience

6 ай бұрын

Justice for Hyaluronic Acid! 😡😡😡

@leannepllpplplpbenn363

6 ай бұрын

On the subject of hyaluronic acid, it would be very useful to know if, in a dry climate, it takes moisture from your skin. Would you be able to advise on that?

@Monica_706undercvr

6 ай бұрын

😂😂

@sarahpaesfrare4776

6 ай бұрын

Please I have the same question aboit glycerin ​@@leannepllpplplpbenn363

@burtnation1357

6 ай бұрын

My skin doesn’t like it

This has nothing to do with skincare, but your crochet top is just.... *chef's kiss*

@LabMuffinBeautyScience

6 ай бұрын

Thank you!

Ma’am I’ve been SCOURING Reddit for this information - specifically around the compound formulas. This video is everything and more thank you SO much

@Nurse_Lucy

5 ай бұрын

Any good brands you've found since this video? I don't have my computer with me on my current contract so looking up the papers she mentioned is hard

@Giancarlo-wv3lv

4 ай бұрын

Buena chama!

@SamFerro

3 ай бұрын

@@Nurse_Lucy sorry just saw this! I was just using dermaticas compound formula which I actually loved for the enhanced azelaic acid but I was curious if the tret was doing anything since (1 the treatments expired within like 2 months and (2 I was able to use quite a bit without dryness / flakiness (even tho my skin is super dry normally and esp dry with generic tret). I’ve since switched to generic tret and I feel like my skins making use of it better than it did w dermatica (tho that could definitely just be in my head).

@melissatranfield4054

2 ай бұрын

@@SamFerro Hi, thank you for sharing this! I have started the Skin + Me compounded formula, and I feel like the added azelaic acid and niacinamide could be irritating my skin + making the tret less effective. I'm thinking to switch to pure tret, where did you get yours from? And what strength are you using? Thanks!

@tommyjohnson2279

21 күн бұрын

​@melissatranfield4054 I have nothing to do with this comment, but I found it interesting. I get mine from nurx it's about the same amount of money but straight from the pharmacy.

you are one of my favorite creators. translating this scientific information into easily understood content is no small feat and you seem to do it effortlessly.

@LabMuffinBeautyScience

6 ай бұрын

Thank you! I've worked really hard at it 😊

@TheBaumcm

6 ай бұрын

@@LabMuffinBeautySciencethat is why I love watching your content as well. Having been in the field, Micro and Genetics background, I know full well that knowing content and delivering it in a digestible way, to those without the same background (people are often so specialized that going even a step outside of their field can feel like foreign language acquisition) while delivering a conclusion that appeals to common sense, rather than manipulation and fear mongering, is rarer than anyone realizes. Plus, the hilarious cutaways, I watch for the hilarious cutaways too!😂

@plaster.art.ho3

5 ай бұрын

Yesss. Nt a big nerd bt I love anything & everything skincare esp tret n ss so having all these digestible info is sooo helpful ❤

@plaster.art.ho3

5 ай бұрын

​@@LabMuffinBeautySciencewe love u!!! 🥰🥰

I live in a place where 0.025% tret is over-the-counter and my skin is very tolerant to It... Using Tretinoin this past year has been great for the appearance and health of my skin. Never dealt with problems related to irritation... And my acne is 99% gone 😺

@SamMKKK

6 ай бұрын

Ah, yes. How does it feel to be God’s favorite?

@noimnotakpoppfpsheacy2526

6 ай бұрын

And which country is that?

@Bodoque-yt3px

6 ай бұрын

@@noimnotakpoppfpsheacy2526most Latin American countries

@lauriannajones

6 ай бұрын

Can it help dry skin?

@kathrynclark1585

6 ай бұрын

Oh my gah I wish the US would allow that!

really informative without being confusing! being able to simplify info like this without dumbing it down is the mark of a great teacher.

Brilliant mention of the “buffering” process around 12min. Super important distinction!

i seriously can’t get over how amazingly informative and helpful your videos are. They are so thorough yet easy to understand.

I switched from a compounded tretinoin from Curology to a generic prescription tretinoin cream. There definitely is a difference. My dark spots are fading quicker with the generic tretinoin cream, even without the added tranexamic acid and niacinamide that was contained in the compounded formula from Curology.

@ALT-vz3jn

6 ай бұрын

The Curology formula wrecked my face. Things are much better with just plain tretinoin from the pharmacy.

@chisoey2986

6 ай бұрын

I use a similar service from Australia called Software. I used compounded 20% azelaic acid, and another formula with 0.0185% tretinoin. Both products contained niacinamide in a hyaluronic acid base. I’ve seen moved on to generic brands (OTC 20% AA and prescription 0.05% tret) and there’s a lot less redness, warming of the skin, and irritation. My tret is 0.05 now which is almost 3x the concentration of my compounding formula and there’s no irritation for me.

@alexmccullough2317

5 ай бұрын

@@ALT-vz3jn same I thought I was the only one. Used it for about two months and I could not stop purging. Purging should only last a couple of weeks

@BlakeGober-mo6sq

5 ай бұрын

Same. Curology wrecked my face. Gave me PIE and after just stopping 1 day my skin is MUCH better. Never again will I use curology.

@shannonm8512

5 ай бұрын

I’ve had the same experience with Curology vs generic tretinoin, since switching to the generic tretinoin my skin is so much calmer and I’ve actually been able to increase the concentration of tret with no irritation. My skin was constantly irritated and sensitive while using curology.

hype! literally been on a lab muffin binge watch this week as a new sub

I started with tretinoin at the age of 16 due to acne. After 5 years I took a break but then returned to tretinoin until I was about 30 when I used oral isotretinoin for 10 months. After my acne was done I had read so much about retinoids that I chose to use them as anti aging. I tried different types of retinoids but went back to using prescription tretinoin five times a week, just a pea size and I moisturise to high heaven. You are absolutely right, the package is extremely important, I store them in the right temperature and follow the instructions on the package. I am 49 and I look like a porcelain doll. Of course SPS 50+ at least 2-3 daily. I am no doctor but i have been reading about retinoids for 30 years and I know you are giving the best and most relevant information. Michelle you are an SPF angel sent to us. Thank you.

@katkatkat5

4 ай бұрын

I’ve been storing my prescription tretinoin in the fridge. Is that ok???

This was SO good!! The bioequivalence regulation explanation was fascinating 💡

Another great video. Looking forward to the next two follow up videos. Especially the cosmetic retinoids. Always watch you !!

This is my new favorite channel!!

Your videos are always super helpful, and this one has to be one of the most helpful ones you've made. THANK YOU.

"It's a bit like hazing, but for molecules." Genuinely laughed out loud at that one. Love your work Michelle.

@sandragee2864

6 ай бұрын

😂😂 I had the same response and posted the exact same comment as you! Since you beat me by 22 hours, I deleted my post and gave your comment a thumbs up.

@Portia620

4 ай бұрын

I just found her and love her video with poor Kenny and the fire!🔥 😂🤣. Then the hazy statement! Creative! Love it

this channel is a gem for dermatologists. thanks for scientific approach! i've subscribed.

Love your videos! I always learn a ton and come away from it feeling empowered to make better skin care choices!

Crazy good video Michelle. I often "feel" like medical professionals and researchers aren't always on the same page, and this was an excellent explanation without going into "doctors don't know what they're talking about" territory.

Thanks for the breakdown Michelle! Great video as always❤

I just finished my MSc in biochemistry and I have always loved all things makeup & skincare… your channel is a mix of my two favorite things to geek out about! 💕

@christine_notchristina

6 ай бұрын

I love your comment and your profile picture, so that means I adore you! Same here!

Thank you Michelle for all the information, your hard work and time! 🧡🧡🧡

Incredible video as always ❤

Really great, understandable video with a high scientific standard. Tank you so much ❤. We really need more of those type of vids wehen it comes to skincare.

Wow. This is by far the most informative retinol video I have ever seen. Thank you!

Your video quality has improved so much! 🎉❤

That was really interesting about the custom formulas! I've been wanting to try them to reduce my skincare routine, but it makes sense that it might not be as effective

Well, this video gave some clarity for my experience with Tret for a year. I tried all the tricks recommended to ease in and prevent irritation. For months, my skin was just very inflamed, irritated and dry. My skin never got used to Tret. I felt like a wasted a whole year. I have carefully tried the Cerave retinol and so far so good. I do have East Asian skin and often have reactions to things I try in addition to that. Tret is just too harsh for me no matter what I try.

@roguecodes

6 ай бұрын

omg someone else!! Every time I’ve tried tret my skin flips out no matter how long I try it

@ZijnShayatanica

6 ай бұрын

That was me w/ Adapalene... I'm considering trying it again, since I started Testosterone & my skin is more oily/congested than it was before. But it's definitely a gamble.

@lelalu101

6 ай бұрын

​@@ZijnShayatanicaI've failed at rx retinoids a bunch of times. Using the ordinary pink serum as part of my routine has kept me going on

You are such a blessing to this community! Thank you for your hard work! ❤

@LabMuffinBeautyScience

6 ай бұрын

Thank you so much!

this was a great breakdown (and fascinating!)

Thank you to yourself and all experts who helped. I'm going to try starting on Retinols this year and I have dry skin so I figure I need to go in easy! Meanwhile my Derm just rx me a prescription Trentinoin cream from a compounding pharmacy that's like $60 a month - so I'm glad I saw this video first!

Omgosh!! SO much great information! Thank you!! ❤❤❤(And I LOVVVVVE your crocheted top! 🥰🥰🥰)

I used Curology's "custom" formula for about 6 months and then switched to the regular tube of tretinion. My Curology formula had 0.035% tretinion, and the regular tube was only 0.025%. I have to say that my experience made me feel that the tretinoin on its own was more powerful despite being a lower percentage, because I was getting the initial purge and sensitivity all over again when I made the switch! This does explain it, thanks. Curology also presents a 25g container as a "2 month supply", when my doctor prescribes me a 20g tube of tretinoin as a one month supply...no wonder I always ran out of the Curology formula weeks before I was supposed to despite using the amount recommended! They do this on purpose, surely, because you can request your shipment early. More money for them.

@miss_jess

4 ай бұрын

what are you doing to use 20g in 1 month?! my prescription is a 25g tube and it lasts me almost a year

@maddie8415

3 ай бұрын

@@miss_jessTretinoin typically comes in either a 20g or 45g tube. I'm willing to bet that yours is 45g. If yours really is 25g I'd be wondering how on earth you could stretch that to a year. I can't imagine it being enough to be effective or applied evenly. I use a 20g one in about 6 weeks, but it's the amount I'm "allowed" to get per month. I have it in a low-ish percentage that I tolerate well and I put it on my neck as well as my face. Not a huge amount, but not the "pea sized" amount recommended for beginners.

I really appreciate the work that you put into producing this insightful video. I was on the verge of trying out a compounded retinoid.. now I will just stick to the OTC brand name retinols I currently use 🙂. You just saved me a bunch of money and aggravation!

Michelle, I *love* your crocheted top! Such a vintage look. It reminds me of a similar top that my grand mom hand crocheted for me which I wore in the 1970’s.

Third!!! Love you, Michelle! You're irreplaceable.

This whole video is why I rely on experts like you 💜 also - sweater is SWEATERING 💜

@mrsbinkbonk

6 ай бұрын

It is isn’t it!❤

I'm so glad that I am your follower from a long time. Thank you for your efforts!

Pretty and smart and honest and funny helped redeem my skin. Thank you for all you do! ❤

Thank you for you hard work on for sharing and explaining the information and your knowledge. I’m grateful for all your videos. Especially this one because we can see here and there everyone praising tret but almost nobody really discuss all the details and difference between the drug, the coumpounded drug and the cosmetic.

You are amazing, tysm for the thoroughness and honesty here 🙏 I used tret for 4 years and it ended up leading to an outbreak of perioral dermatitis. Now my skin is so sensitive and reactive that almost any product can trigger the PD again (as well as other conditions now too) and it's SO hard to manage and treat, even with antibiotics. I wish people were better informed about the pros and cons of different actives, there's so much mystification in this industry.

@sheridanbeverley9173

6 ай бұрын

I sympathise with you. I didn't use tret for as long as you but I tried it (0.05% once a week for 4 weeks) and I now have rosacea and the skin on my face is extremely sensitive. I regret it so much. My poor skin barrier 😔

@tortadepimenton

6 ай бұрын

@@sheridanbeverley9173I’m so sorry you went through that :( but yeah 0.05 is pretty strong as a starter

@tortadepimenton

6 ай бұрын

@@sheridanbeverley9173you are going through that***

@CrystalRose1111

3 ай бұрын

@@sheridanbeverley9173Tretinoin obliterated and aged tf out of my skin, I even got a dry/raw patch that left a terrible scar. This all went away slowly once I stopped using it. If you live in a super dry climate and don’t have great water quality, please do not use tret. If you can’t provide the hydration that your skin needs, tret will make your lines and wrinkles WORSE.

@NarminSultanova-ds5yt

3 ай бұрын

Hi im sorry for you, did your skin healed?​@@sheridanbeverley9173

Michelle posts, I stop whatever I'm doing and get to learnin'!

Amazing! So clear 😊

Thank you SO much Michelle - this is the MOST useful video on choosing retinoids I've seen yet! I also live in Australia and previously used Stieva 0.025% tretinoin. Is it now discontinued? I used Retrieve 0.05% which was too strong. What other brands are available in Australia? (It's very difficult to find any definitive information online.)

Excellent video. Really informative. 👏🏻👏🏻👏🏻

Thank you so much for explaining all these things in depth!

Excited for cosmetic video!! X

This was so informative, thank you!

Love this channel. Thank you!

This video opened my eyes. Thank you!

how am I supposed to focus on the topic of video with this georgous crochet work fighting for my attention, it's just too good

That explains perfectly why my Saint Derm (healed my acne with isotretinoine and supervised the long scar removal process) is so strict when it comes to the treti brand. It' s OTC in my country so he always insists: "IT MUST BE FERRER LABS. MUST MEANS MUST, I KNOW WHAT I' M TALKING ABOUT". I' m gonna share your vid with him so he can nod in peace for 17 mins😉. Thank you for your hard work. Happy Whateveryoucelebrate🧛🏻‍♀️🖤

Duch helpful information!🥇

hahaha we did it, Joe! Thank you, excellent work, Michelle!

I'm intrigued by the science behind skincare. I appreciate how you make it palatable and easier to understand! I've been using OTC Adaplane for over a year now with no pronounced irritation. I considered trying out a compound formula from Dermatica or Apostrophe since cosmetic derms are sparse in my area, but now I'm reconsidering. Adapalene has been working for me and I have enjoyed the results, though my acne isn't completely gone. Maybe I should just stick to Adapalene while I search for a cosmetic dermatologist who can advise if trying a stronger, prescription-strength Adaplene or a low percentage of Tret would be the best next step for me. Thank you for sharing your knowledge and hard work with us!

@Alex-dj9qj

5 ай бұрын

I'd say stick to what works, I was on tret before and it wrecked my skin. Adapalene gave me glowy and smooth skin after, something that tret never could. Plus no irritation 🤷🏻‍♀️ I don't want to discourage you but if something works for you, stick with it long-term unless it's damaging your skin in some way obviously. You can try and trial some tretinoin to see for a few months maybe

Thank you so much for including compounded skincare,

I am Scandinavian and very pale. I always thought I had a bit sensitive skin but when I started with retinol and then switched to adapalene a few months later, I never felt any irritation, nor got any redness. I didn't really read much about "and I more or less slapped it on like moisturizer" (avoiding eyes) and then added another layer of moisturizer cocktails from hadalabo and cerva (two of my favourite brands) and at the end sealed it all in with a good layer of vaseline to make it penetrate deeply and went to bed. Still no irritation ever and my skin became 10 years younger within a year. I have now dialed down on the adapalene, mainly because it seems a bit of a waste to use that much, but honestly never had as much as an itch or a red spot.

@Alex-dj9qj

5 ай бұрын

Adapalene is so good! My skin reacted badly to tretinoin then I tried Differin (I had acne so I needed something). Differin changed the game! 3 months later, not much acne anymore, no irritation or redness and glowy skin!! I once couldn't believe my skin texture after I had washed it and hadn't applied my moisturiser yet. I looked at it and it seemed to have a "shiny" film and I was so weirded out because I thought I hadn't washed my face well. It turned out that was the texture of my skin LOL, very smooth and glowy even without products on. It's wild. I don't ever plan on giving up Differin especially since it's easily available here in the UK through a pharmacist.

@Lexmorningstarnz

5 ай бұрын

I get zero irritation from tretinoin either, but I did with over the counter retinol. So odd haha

@myown2101

3 ай бұрын

I started with tretinoin, but had too much irritation. Used adapalene for about two years with no irritation. Simple skincare routine. Switched to tretinoin about two months ago with zero irritation too minimal irritation and purging. The greatest part about adapalene - you can pick it up at any drug store.

@LivMeadowvalley

3 ай бұрын

@@Alex-dj9qjwhat brand do you use?

@English.Nazmeen

Ай бұрын

I think we only have Differin brand adapalene in the UK. At least, that's what I see everywhere. ​@LivMeadowvalley

Awesome video ❤ I always wondered if this custom formulas are actually tested for efficacy as a whole, or if they just assume it is, based in the tretinoin percentage. I am using now a custom one just because is easier for the adaptation period. I can use it every day with small percentage and increase it gradually, and I don't need to measure the ideal amount. But, my idea is to switch to prescription once I have reached a percentage that is available as a drug (I think minimum is 0.025). On this topic, I would love to see next a guide on how to choose the best retinoid prescription 😊 There are so many options and brands, not sure yet what is best for me. Thanks ❤

Thank you so much for the amazing work! I love your channel and all the information you share. I have acne and I tried out tretinoin for the first time in november. Before that, I had been using adapalene for the last 8 months and my skin was really better (I had an awful breakout at the beginning of the year). I followed the steps from your tutorial video. My skin started to breakout since the first application, I kept using it for 4 weeks, but it didn't got any better, only worse. So I stopped using it and I'm treating my acne with benzoyl peroxide. Wondering if I should go back to adapalene and just stick to it. I wanted to try tretinoin because of the evidence in anti-aging effectiveness, but after this breakout, I don't know if I should try again :/

Lab muffin is the best.

good lordie you're ACE. Thanks - I 've tried explaining the difference betwixt the OTC and prescription , to my friends and 9 times outta 10 - just give up. Hence forth this vid shall be my go to. Cheers

Thank you for this scientific deep dive. I use a prescription service (Agency}. I have used prescription tretinoin for years and constantly battled irritation. My formula has Tretinoin, Niacinimide, tranexamic acid and Panthenol. If there are formulas out there that are separate for the $30 a month I payI would love to hear about it. Also I got so tired of layering all these different products on every night and many times would quit before completing the seven steps needed. With the Agency I use a moisturizer and their formula and it simplifies things. Love your scientific take on everything

I really love curology because they educated me and informed me to use sunscreen (I know, I know). I started using over the counter products used from the formula they gave me and my skin has already improved sooo much.! My texture and hyperpigmentation improved…. But I ditched them for Dermatica. Curology’s face wash they gave me seems to have the shards or crystals mentioned, and I wanted tret so I made the switch. When I feel comfortable I’ll change to just tret and not the formula. Nice video and thank you for the information 🤗

wonderful video! my coworker and i were just talking about wanting to figure out a good starting place for retinoids!

Following you in all platforms

As a pharmacist who worked next to a dermatology clinic, I really love your videos! And you're 100% right. Pharmacists here have the right to choose and adjust the base and vehicles. Unfortunately since parabens fell out of favor and most bases (other than very hydrophilic ones) don't have them, the microbial stability is very limited to 3-4 months like you've said. We used an unguator for compounding, but even then you have to manually homogenize the powders and there is no chance you can get them to a fine enough particle size by hand for the best effect, especially with ingredients that require it (most formulations here are suspensions). A few times we've had salicylic acid creams where the crystals didn't dissolve properly and it was a nightmare to deal with.

Unrelated to the video, but the color of your top looks so good on you!!

Perfect timing!!! I was considering whether or not to try to get a tretinoin prescription since using OTC adapalene daily hasn’t helped enough (been using it for over a year)

@lilivd4359

6 ай бұрын

What about trifarotene?

@fabuloustobi9684

6 ай бұрын

@@lilivd4359what’s the upside?

Sooo good. TY Michelle 🤍

On an unrelated matter- I adore your top!

@LabMuffinBeautyScience

6 ай бұрын

Thank you!!

Super off topic, Michelle, your bangs are BANGINNN 😆 It's not budging, what did you use to set it 😅🤔

Love your sweater!! Maybe I can make one in my spare time?

Instant subscribed! Love your content. It’s sad Stieva has been discontinued, and Retrieve just does not agree with my skin. I had tretinoin compounded and it burnt my face as I believe they messed up the strength as they changed it from 100g to 50g and 1 repeat and probably didn’t change the concentration

Love your top!

Off topic, but I love your top! 😍

Thank you for this video, I’ve been using tretinoin for 3 years now, a very low percentage didn’t help with my problems of acne, so my curology doctor prescribed me a more stronger one, my skin has never stopped peeling and is very dry to the point that I need very occlusive creams, but the heavy oils in them make my skin break out even more, I have stopped tretinoin for 4 days, the peeling has stopped, but I’m getting back the redness and little bumps that I had before using tretinoin, I’m just a mess, thinking on using adapalene to see if that works better. Thank you for your videos as they are very educative!!

yes, physicians often don't even know what pharmaceutical technology and biopharmacy are. pharmacists are the people that learn every little detail about it over years at the university.

Its just such a hassle to try and get a script. So I don't think I'll ever have access to it. Looking forward to your future videos in retinoids 😊

@samnicol9388

6 ай бұрын

I just asked my regular Doctor, worth a try.

@oryxs

6 ай бұрын

iherb has 0.1% differin adapalene gel.. I haven't ordered it myself yet but I'm planning to.

Great video very interesting

Hi love all your videos skincare routine have a wonderful christmas 🎉 😊 xx

Love and thank you for all the research you do. With all your thorough information, my skin looks better than ever. Could you please do a video on how to fade scars from surgery. I have a scar on my nose from having skin cancer. Im self-conscious and it's very hard for me to go out without makeup. Thank you in advance, love your channel ❤❤

@mouse2390

5 ай бұрын

Silicone according to my plastic surgeon. I use silicone scar sheets on clean dry skin in the morning and silicone scar gel massaged in at night. You can also use vaseline but silicone is the only thing medically proven to minimize scars. Also never, never skip sunscreen...5 minutes of sun will turn that scar a red that you might never get rid of. I had a cyst removed from my cheek 6 months ago and my doc said full healing could take a year...it's doing great so far and I'm much less self-conscious about a piece of flesh-colored tape on my face than I was about that cyst. Nobody looks at you as harshly as you look at yourself--plus you've gone through skin cancer!--be proud of your scar.🏆♥

I just discovered you randomly and have loved the knowledge you shows in this video. I know quite a bit about retinoids and all make sense and was wuite a satisfying video to watch! Last time I was in Greece I picked up tazarotene 0.1 over the counter by a cosmetic brand. Only used since a short time but it seems pretty intense - it is in a very moisturising formula but still getting the uglies of a strong retinoid (using a tiny amount over moisturiser only twice a week) I might try and get a prescription formula if I carry on with usage since I feel better about prescription. (and in the Uk are also muh cheaper than OTC/online derm service, as GP can often prescribe them)

Hi Michelle, have you ever looked into any of the data/research around the question of tretinoin and/or retinol being harmful to meibomium gland cells in the eyelid? I realize you are not an eye doctor but your ability to understand research and translate it to the general public is so appreciated. ❤ I understand MB glands do wither with age on their own, and theres a body of thought that only oral isotretinoin has been shown to damage MB glands, but theres still the question/uncertainty around the possibility of topical reintoids doing the same, even if not directly applied to the eye area, and theres one video ive seen on yt from an eye doc that advises extreme caution and some eye docs recommend not applying to the face at all. A review of what literature we do have on the topic would be an epic video if you ask me! Especially since retinoids are becoming soo popular .

Sorry just started the video but i cannot get over how cute your top is omg

omg this is just what I needed! Using 0,05% tretinoin rn but it‘s just waay too irritating. I can‘t find 0,025% either here in Germany but I wasn‘t too sure about the cosmetic retinoid. Can you maybe make a compilation of which cosmetic products (actual product) you find effective? thankyou!

@issingno7814

6 ай бұрын

Geek & gorgeous has a retinal and they do ship to Germany

@louk6848

6 ай бұрын

You can buffer with a thin layer of moisturiser before, then use a tiny amount of tret with the dotting method

@BlueRaven73

6 ай бұрын

​@@louk6848Michelle mentioned in a different comment that she personally mixes hers with moisturiser so that is definitely an option

@AaronFigFront

6 ай бұрын

Paula’s choice is good.

@InimeKai

6 ай бұрын

Have you tried tret micro?

Love your videos as I'm a science nerd as well. But I am in the comments section to ask about your top which is totally amazing. Please let me know the band/creator ❤

god bless, this is such interesting and helpful information.

I love your videos! It is so nice to hear information from the credible source and not the influencers who got their education from google! Could you please make a video explaining if you can layer other active ingredients with tretinoin. I love putting L’Oréal hyaluronic acid first or putting 10% glycolic acid first. My skin torelates it really good. But i am so afraid that if I layer other product on my face before or after tretinoin I will destabilize tretinoin formula rendering it being less effective. I could not find this information anywhere.

I have really sensitive skin, so it was hard to find an acne solution that worked for me. Tretinoin was surprisingly much more tolerable and effective for me than Duac and BHAs.

I just found your page I am obsessed with what you do here I love you! My question is what if I use something like a stronger strength retinoid as part of a once a month skin routine and an over the counter retinol for every day use? Would this be similar to your idea to layer them or would it just cause irritation due to not using the prescription strength product every day

this top is unbelievably cute!! did you make it yourself?

Great video, thank you so much for all the effort you put into it. I used skin&me tretinoin/azeleic/niacinamide for about a year and the irritation never settled. I finally switched to Geek and Gorgeous retinAl and my skin has never been better

Great information. But also, where did you get your crocheted top from?? 😅

Tretinion and similar drug products are so hard to come by where I'm from. I have been struggling with acne my whole life and never once was this even suggested to me. I wish it was easier to get,since it would greatly help my skin for all the numerous conditions listed in your video.

I’ve been using all types of retinol for over 10 years. I started with pharmacy brands then moved very slowly through all the Australian retail products getting stronger and more expensive. I’ve used retrieve trentinoin 0.05% for every second day for two years, it’s aud $65 for 9-10 months supply. I was looking for anti aging (negligible improvement) but for me the skin smoothing, reduced pigmentation, less single pimples and reduced sensitivity to lots of other things keeps me using it. ( I had very reactive skin, now I don’t, something I hadn’t heard about in retinol journeys) I never buffer, I apply every second day and used tiny tiny amounts until I was used to a product but still can’t retinol everyday without a light flake. I used Paula’s choice 1% retinol happily for a long time until they reformulated with dimethicone which blocked my pores gradually causing pimples. I should have gone to trentinoin sooner, it has saved me a lot of money.

@brittalex7024

6 ай бұрын

$65 for a 9-10 month supply seems like a very reasonable price

@Kat333ify

6 ай бұрын

I started the same way as you 9 years ago, and second to the experience that my skin is far less reactive now and just generally happier. Actually, it IS talked about - quite a few specialists say that tret or any retinol really is making your skin over time thicker so-to-say, and this results with much less problematic skin. Thats why also tret is suggested for rosacea, but of course only introduces slowly over time from light concentration to stronger. I started with 0.3 over the counter retinol, now using 0.05% tret every 3rd day and retinal in between.

@davidsotir4318

6 ай бұрын

Does Retrieve also come in a 0.025% strength?

@Mellyouttaphase

5 ай бұрын

I have just started on Retrieve 0.5% . Am now using three times a week and so far, no issues. Really anticipating the journey. Costs me a lot less than the retinaldehyde serum I was using, too!

@Billie-dp2oo

5 ай бұрын

Would you be able to recommend a good sunscreen for Australian sun

Thank you. Always had a feeling the compound formulas were much less effective than the generics. Used a subscription service for a couple of years and it just gave me irritated skin. The generic just worked as intended, and with no side effects.

Hey Michelle! Obsessed with your videos, could you please make that video about cosmetic retinoids? And include some that you recommend for an experienced retinoids user? I have used tretanoin 0.025 and I loved it but my skin got sooooo dry, are there any non-prescription retinoids that could give me similar results? (Skin smoothing, evening tone, reducing fine lines). Thanks! P.s keep doing what you are doing, it’s so amazing hearing a voice of reason in a sea of misinformation and fear mongering

@LabMuffinBeautyScience

2 ай бұрын

Getting there! It's been derailed by a huge benzene-related video 😭

You’re the Ann Reardon of beauty science!!! :)❤

Pleaseeee make a video about topical spironolactone for acne! I started using it from apostrophe but it’s compounded with clindamycin. Will it work?