Sernova’s Cell Pouch System tackles diabetes
Ғылым және технология
Sernova Corp. is a Canadian-based clinical-stage biotechnology company that is developing its Cell Pouch System.
This is a novel implantable and scalable medical device with immune protected therapeutic cells, for the treatment of chronic diseases such as insulin-dependent diabetes, thyroid disease, and blood disorders that include hemophilia A.
On implantation, the Cell Pouch forms a natural vascularized tissue environment in the body for the long-term survival and function of therapeutic cells that release essential factors absent or deficient in patients with certain chronic diseases. Sernova is also advancing a proprietary technology to shield therapeutic cells from immune system attacks with the goal to eliminate the need for chronic, systemic immunosuppression.
In May 2022, the company announced a global strategic partnership with Evotec, providing Sernova with a potentially unlimited supply of insulin-producing islet cells to treat patients with insulin-dependent diabetes (type 1 and type 2).
Sernova continues to progress additional development programs utilizing its Cell Pouch System: a cell therapy for hypothyroid disease resulting from thyroid gland removal and an ex-vivo lentiviral Factor VIII gene therapy for hemophilia A.
We spoke with Philip Toleikis, president and CEO of Sernova at Bio-Europe in Leipzig, Germany.
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@sernovacorp.1312
#biotech #medicaldevice #diabetes #hemophilia #thyroid
Пікірлер: 53
Need this now for MANY....God bless your work!
@user-mf2wu1dr2p
Жыл бұрын
Ia type 2 siabetic be elegiblw for this project
*You Did Not Choose To Be Classified As Diabetic, But You Can Choose To Fight Back Against Diabetes* 💪
my 3 year old son has diabetes typ 1... its my greatest hope that one day he will be able to live normally 😭 I hope this will soon become standard therapy for diabetes typ 1
@mehmetalikutlu3513
Жыл бұрын
Cocuklara uygunanacakmi benim oglumda 3 yasinda tip1li
@qediramirov4600
6 ай бұрын
How is your son now? Is there new news?
Eagerly waiting for a cure for type 1 diabetic ...🙏
Very exciting. Been a diabetic for 42 years and would love to be part of the program.
This is the first time I’ve been excited about the next step in curing diabetes. Sounds very promising. I would take out a mortgage to get this treatment if it was an option!
@KM-vc7iy
3 ай бұрын
The cell pouch is made of woven polypropylene mesh and is known to cause severe side effects in hiatal hernia patients that have had surgery using this same material. So while someones type 1 maybe cured they could be left with something just as harmful in the long run.
My aunt died of diabetes, she had to go through amputation. Hopefully your work will be successfull, and help a lot of people around the world!🙏
@babycakes8434
Жыл бұрын
@Clipped You get gangrene from the diabetes If I am not mistaken.
@senanur1983
11 ай бұрын
@useduser Too much glucose infects the legs and toes. If you do not watch what you eat (carbs and cakes), even Insulin wont help you.
Thanks, thanks for all doctor, i pray ever to you 🙏🙏🙏
Congratulations. The result of the technology should reach the common man in the Developed and Under-Develpoed countries.
@sukant08
Жыл бұрын
That'd would unfortunately take multiple decades mate. Meanwhile there are startups working in India on a low cost insulin pump costing less than 500 dollars. That should give some support to 3rd world countries till the time this cure becomes affordable
Keep up the good work and may God lead you throughout your research until completion. But it costs a leg and an arm.
Sernova ❤️
How long would the islets transplanted in the cell pouch, last, though? Do they reproduce inside the pouch, wouldn't you eventually need to get 'recharge' or something of islets, after x amount of years?
Arkadaşlar gerçekten tip 1 kesin tedavisi çıkıcak mı
Please type2 manny people hope treatment
@Dangerdave_
Жыл бұрын
exercise and diet is the cure for type 2
Tread with caution as sernova uses a woven mesh on the cell pouch which can cause devastating life long side effects on the human body.
Sounds great but I was so disappointed to know that the cell pouch is made of woven polypropylene mesh which is known to cause severe side effects in hiatal hernia patients that have had surgery using this same material. So while someones type 1 maybe cured they could be left with something just as harmful in the long run.
It'll be ridiculously expensive by design. So it's no good.
That makes no sense to be charging $300,000 USD nobody can afford that.
@russellseaton2014
Жыл бұрын
Diabetics can and do have Type 1 diabetes for 50-60 years. Or longer. The newest insulins cost $600 per vial. Two vials per month. $14,400 annually. Insulin pumps cost $6000 and last four years. The supplies for the pump cost couple hundred per month. CGMS (continuous glucose monitor system) cost about $130 per 10 days for the new Dexcom G7 sensor. $3600 per year. Similar price for the older G6 and other CGMS. Blood glucose testing strips are about $1-2 per day. $500 per year. Quarterly endocrinologist visits are $300 each. Plus a couple hundred for blood tests each year. Then add in the annual retinopathy test at the eye doctor. Another couple hundred. Ambulance visits from the paramedics and the IV of glucose are a few hundred each time. Emergency room visits when the paramedics can't resuscitate the diabetic on the spot and release him, are several thousand dollars each. A diabetic will easily go through $500,000-1,000,000 in medical costs through his life. For those with serious complications such as kidney disease or amputations or eye surgery, double it. A $300,000 cure would be well worth it. But the solution given in the video is not a cure. Its a different treatment with its own medical costs. But maybe this treatment would result in less cost over the long term by eliminating the expensive ambulance, emergency room, amputation costs. And give a better quality of life.
@bestmixvedios5987
11 ай бұрын
@@StotheEtotheB what about people living in arab country will insurance pay 😢
If you are experiencing servire hypoglycemia and are 100% insulin dependent isn't that a self-inflicted scenario?
2023 is going to be a great year people with diabetes and Sernova.
@vincentwiese8414
Жыл бұрын
It's just a bunch of false hope this technology never goes to human clinical trials.
@vincentwiese8414
Жыл бұрын
Just a bunch of False hope. It's not affordable.
@clutchbeyers
Жыл бұрын
@@vincentwiese8414 its already in human trials and doing well lol, you dont know anything
@clutchbeyers
Жыл бұрын
@@vincentwiese8414 insulin is super affordable though
@vincentwiese8414
Жыл бұрын
@@clutchbeyers insulin in America is $340 per vial.