Coagulation is classically divided into the extrinsic and intrinsic pathways, which both run into a common pathway. The newer cell-based model attempts to describe how the sequence of events occurs under physiological conditions. The main difference is that the cell-based model of coagulation doesn’t separate the two pathways, but describes several stages in which coagulation proceeds.
Outline:
00:00 - Introduction
00:50 - Initiation
02:44 - Amplification
04:25 - Propagation
06:52 - Feedback loop
08:16 - Summary