Hemostasis: Lesson 3 - Coagulation Cascade and Fibrinolysis

An overview of the coagulation cascade and fibrinolysis, with emphasis on the contemporary model of coagulation (as opposed to the traditional extrinsic vs. intrinsic pathways). The role of vitamin K is also discussed.

Пікірлер: 49

  • @abumais100
    @abumais1009 жыл бұрын

    Three > Two > One ... Doctor Eric is the best One

  • @sunving
    @sunving Жыл бұрын

    Great lecture , I was shocked to find out that I watched this 3 year ago already. Time fly !

  • @Eric-bq5ou
    @Eric-bq5ou9 жыл бұрын

    Thank you for making concise, yet still very detailed videos! Can't wait for the rest of them in this series!

  • @danielkiprov7998
    @danielkiprov79983 жыл бұрын

    Incredibly well explained and visualized. These lectures are a real gem!

  • @Owmed
    @Owmed4 жыл бұрын

    These lectures are so dense and detailed, I love em! Thanks again, you are a life saver!

  • @islammmi
    @islammmi9 жыл бұрын

    Keep up ... I like your very organized way in simplifying issues ... Waiting for the rest of hemostasis lectures ?. You are such a genius

  • @StrongMed

    @StrongMed

    9 жыл бұрын

    Thanks for the message. The rest of the hemostasis videos are coming, but I took a 2 week break over the holidays, and am going to post a few non-hemostasis videos in early Jan, so subscribers who aren't interested in hemostasis don't get too bored. But they are coming over the next couple of weeks to months.

  • @rosun3437
    @rosun34377 жыл бұрын

    systematic presentation is what makes your lectures easy to learn... I find it very useful

  • @mariuspheiffer214
    @mariuspheiffer2147 жыл бұрын

    Still the best lectures I have come across on coagulation. Brilliant! FOAMed rocks!

  • @veronikapleskova3349
    @veronikapleskova33498 жыл бұрын

    Thank you so much for this video! This is the first understandable explanation of hemostasis which I've ever met.

  • @jennydanielsbacka
    @jennydanielsbacka8 жыл бұрын

    Thank you again...now hemostasis is so mych more clear than before I watched these lessons!

  • @nsparvana
    @nsparvana9 жыл бұрын

    Thanks for this wonderful educational video. Please post the next in the series at your earliest.

  • @sunving
    @sunving4 жыл бұрын

    Thank you Dr Strong . I may need to watch a couple more time to get .

  • @TheMagicStrawberry
    @TheMagicStrawberry9 жыл бұрын

    Thank you very much for this video! Im always waiting for a new One so i can learn more!! Keep up this excellent work

  • @789DarkWolf
    @789DarkWolf6 жыл бұрын

    Finally, I understand this difficult topic. Thank you!

  • @eduardodonascimentoalbano7921
    @eduardodonascimentoalbano79214 жыл бұрын

    Amazing, i finally mastered this topic. Thank you!

  • @sumanraja21
    @sumanraja219 жыл бұрын

    excellent video sir, so difficult topic made clearly understandable !!! You are a Genius.

  • @shawnbalk9611
    @shawnbalk96117 жыл бұрын

    This was very helpful. If you pause it and memorize things for a few minutes in between slides, slides will build on each other enough to understand and remember the material. I spent an hour on this video and feel that I can remember most of the material.

  • @stevenruizmontes4354
    @stevenruizmontes43548 жыл бұрын

    congratulations. you are a great profesor.

  • @nadawaheed6812
    @nadawaheed68122 жыл бұрын

    Sir you are a true legend!!! You never failed to break down the hardest topics for me.. I'm so grateful for you and your efforts may Allah bless you.💙💙💙💙💙

  • @omairkashif

    @omairkashif

    Жыл бұрын

    subhanAllah

  • @jaquelinemanuel5716
    @jaquelinemanuel57168 жыл бұрын

    Well explained! Thank you!

  • @mokhles703
    @mokhles7032 жыл бұрын

    Fantastic video.

  • @doctormushahid6470
    @doctormushahid64702 жыл бұрын

    great sir i like all of your videos it help me to build concepts which i have missed in my basic sciences subjects thanks for all and keep it up

  • @wejdanalwael7702
    @wejdanalwael77026 жыл бұрын

    Thank you sir for making it understandable.

  • @patrickwillyongbwa9547
    @patrickwillyongbwa95479 жыл бұрын

    thank's for this great presentation

  • @sclairev7669
    @sclairev76696 жыл бұрын

    You deserve to be followed! I Subscribed!

  • @StrongMed

    @StrongMed

    6 жыл бұрын

    Thanks for watching!

  • @tablettesamsung9769
    @tablettesamsung97697 жыл бұрын

    Very nicely explained

  • @charlotte9777
    @charlotte97774 жыл бұрын

    thank you so much for this video!!

  • @snoopytroops
    @snoopytroops8 жыл бұрын

    that EM image is a beaut!

  • @Fahad-iw5to
    @Fahad-iw5to11 ай бұрын

    You are my hero ❤

  • @mariociencia12
    @mariociencia123 жыл бұрын

    Please make a video about interactions amid factor XII, prekallikrein, and HMW-kininogen!. I think it is not such a useless pathway. For example, this pathway is related to the formation of bradykinin, a remarkable molecule related to inflammation. Furthermore, this pathway is also associated with the creation of polyanions from ATP. These polyanions also seem to be linked to the immune system. It would also be a delightful video about the molecular mechanism of HIT (heparin-induced thrombocytopenia). Once more time, very thankful for this handy video!

  • @gracezhang0708
    @gracezhang07088 жыл бұрын

    Thank you so much!!!!!

  • @beaucheinternationaluk9678
    @beaucheinternationaluk96786 жыл бұрын

    Where are the rest of the haemostasis lectures? Please upload them.. I am a fan!

  • @ohoodalmalki1542
    @ohoodalmalki15428 жыл бұрын

    Thank u, I am master student u help me a lot

  • @mariociencia12
    @mariociencia124 жыл бұрын

    Excellent video! However, I missed more animations, as in the previous video of this magnificent series about hemostasis. Instead of just indicate the name of molecules in a scheme, it would be much more interesting showing them in the form of geometric figures. Despite that, the video was very helpful!

  • @ferdiefatiga3443
    @ferdiefatiga34434 жыл бұрын

    Thank you! 😊

  • @nidhinidhi213
    @nidhinidhi2137 жыл бұрын

    Plz post mire videos..some are not complete Excellent job

  • @zhafirahramadhanty
    @zhafirahramadhanty8 жыл бұрын

    helped a lot. thanks xoxo

  • @Eric-bq5ou
    @Eric-bq5ou9 жыл бұрын

    You may have mentioned this, but what allows for the coagulation cascade to initially prevail over the antithrombitic? Is it just based on the magnitude of TF present after endothelial damage?

  • @romeolhk1008
    @romeolhk10086 жыл бұрын

    Dr. Eric, your videos are superb! May I ask 1 question? How does platelet aggregation and coagulation cascade rely on each other as you stated in 18:21 ? I know thrombin could activate platelet as you stated in Lesson 2 9:08 , but how could platelet aggregation influence coagulation cascade? Thank you.

  • @romeolhk1008

    @romeolhk1008

    6 жыл бұрын

    Oh I found the answer in Lesson 2, platelet will secret factor V when activated. So excited to find these videos interlinked. Thank you.

  • @kurootsuki3326
    @kurootsuki33265 жыл бұрын

    everything makes sense now

  • @pilids3514
    @pilids35145 ай бұрын

    At 7:23 , what activated the factor V? II thought trhombin activates it but at this point of the initiation phase there isn't activated thrombin?

  • @fishribbon
    @fishribbon8 жыл бұрын

    Epic

  • @sunving
    @sunving Жыл бұрын

    Thanks ! Good lecture but how could I remember that :(

  • @Dazzletoad
    @Dazzletoad5 жыл бұрын

    Why is vitamin K being discussed after fibrinolysis? Without relevant factor gammacarboxylation, there won't even be a clot to breakdown. 🤦🏻‍♂️

  • @asmaa2315
    @asmaa23158 жыл бұрын

    o my god i didnt understand any thing