Season 5 Episode 3 (Ranking of Minoxidil and FIN in FPHL, Oral Minoxidil Swelling, Anticonvulsants)
STUDIES REFERENCES
Gupta AK et al (starts at 9:45). Relative Efficacy of Minoxidil and the 5-alpha Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients: A Network Meta-analysis. JAMA Dermatol. 2022 Feb 2:e215743.
Gupta AK et al (starts at 11:06). The relative efficacy of monotherapy with 5-alpha reductase inhibitors and minoxidil for female pattern hair loss: A network meta-analysis study. J Cosmet Dermatol. 2023 Jun 29
Desir N et al (starts at 31:42). Insights Into Perceptions and Gender Differences About Androgenetic Alopecia in an Observational Study of Commenters on the New York Times Oral Minoxidil Article. J Cutan Med Surg. 2023 Apr 21;12034754231170215.
Brianna M. Goodwin Cartwright et al (starts at 34:54). Changes in Minoxidil Prescribing After Media Attention About Oral Use for Hair Loss. JAMA Netw Open. 2023 May; 6(5): e2312477.Published online 2023 May 9. doi
J F Mir-Bonafé et al (starts at 42:17). Morning Periorbital Edema Related to Low-Dose Oral Minoxidil. Actas Dermo-Sifiliograficas. 2023 May;114(5):460-46
Dlova et al (starts at 48:40). Pericardial, pleural effusion and anasarca: A rare complication of low-dose oral minoxidil for hair loss. JAAD Case Rep. 2022 Aug 11;28:94-96.
Rissardo J et al (starts at 50:15). Antiseizure Medication-Induced Alopecia: A Literature Review. Medicines (Basel). 2023 Jun; 10(6): 35.
Пікірлер: 14
Thank you so much Dr Donovan, as you continue to share your research with us.....
@donovanmedical9780
11 ай бұрын
Many thanks for this!
@hhh-nm3we
11 ай бұрын
Hi doctor i’m really sorry to bother you but i don’t know if my comment are showing . i will ask one last time i’m so sorry but basically in eyebrows ffa and lpp are tacrolimus and topical steroid once or twice weekly even usefull in stopping the disease progression or is really the only option to go for more powerfull systemic medication such as hydroxycloroquine for someone with an already « decent » protocol which in theory should stop already eyebrows ffa or lpp ( oral min + bimatoprost + dutasteride + isotretinoin + steroid injection + lllt ) Thanks you very much i really don’t know what to add especially since i’m scared of immunosuppressive medication and i already tried cyclosporine ( maybe nac and pentoxyfillinecoulf be usefull ? ) I would love to just stop the disease progression and keep my eyebrows. Thanks you so much for your time and answer
@donovanmedical9780
11 ай бұрын
@@hhh-nm3weIn very mild disease states, this may be useful but not in more active disease. Yes, it is possible it contributes to some degree of slowing of the disease but what most patients are looking for is not slowing but stopping. But the answer to this question is that yes, it may do “something” positive to slow down the rate of loss but may not actually turn the disease off in many individuals with more active disease. Be sure to keep close follow up with your dermatologist.
@louis1pottier674
11 ай бұрын
Thanks you very much doctor so what would you recommend to " shut down " the disease and stop his progression in such case?
@donovanmedical9780
11 ай бұрын
@@louis1pottier674 That’s a big question but the answer is here !!!! kzread.info/dash/bejne/k2uko6ShoraWndI.html
It is interesting to see 70 and 80 yr olds are interested in oral minoxidil. As we have to weigh the side effects against the predicted response we are going to get on longterm use and I wondered is the effect we are going to get depends on the number of remaining follicles in the affected area per sqmetre and is that we can expect only the remaining hairs to be get thicker but no new hair growth ? This will vary depending on the stage of androgenic alopecia ?
Dear Doctor, I have been diagnosed with FPHL grade 2 and I have been on oral finasteride 2.5mg (for 1 year) and oral Minoxidil (started with 0.0625 for 2 weeks, 1.25 for 2 weeks and 2.5mg for 9.5 months). I have seen increased hair shedding for about 8 months, and it continues. (At the same time as I started full dose Minoxidil ie. 2.5mg, I got A cell PRP also done). Will the hair shedding EVER reduce or stop? Will increasing or reducing the dose of Minodixil help to reduce hair shedding? Is the hair shedding seen with Minodixil use proportional to the dose? So far I have had no side effects from Minodixil with 2.5mg for 9 months. Actually, my hair fell out with the bulbs and clogged the drain. Even before I started the treatment it used to come out in clumps. I read that if the hair come out in clumps it cannot be andogenetic alopecia or FPHL. When I asked my doctor he said that it could also have a component of Telogen Effluvium. Pls, advice what should I do?
@donovanmedical9780
8 ай бұрын
I would need to see your scalp. That's the only good way to figure this out. I have no idea if shedding will stop as I don't know what you have. PRP needs to be done 3-4 times per year forever so there's no such thing as a one time treatment. All in all, I need to see your scalp up close and review your story from birth until today and review all your blood tests. Certainly autoimmune issues, COVID shedding, vaccine related issues, LPP, and other scarring alopecia need to be 155% ruled out here. Be sure to see an expert! A biopsy may be needed.
@inderjeetbhatia6380
8 ай бұрын
@@donovanmedical9780 Thank you so much doctor for taking the time to reply. Is the hair shedding seen as a side effect of Minoxidil proportional to its dose? Thanks
Thanks,Dr.Donavan Is the presumed risk for skin cancer present with dutasteride too ? Also is there any evidence of breast cancer in real world experience for finisterre?
@donovanmedical9780
11 ай бұрын
donovanmedical.com/qow-posts/finasteride-breast-cancer
Sorry it should be breast cancer