Recrystallization

Recrystallization is a powerful method for purifying solid compounds. In this video, I give a brief overview of the technique and demonstrate how to carry out a recrystallization of an unknown organic compound. Purification of the compound is then confirmed by TLC.
This experiment is based on a procedure described in the CHEM 216 Lab Manual, which was prepared by several members of the organic chemistry faculty at Cal Poly.

Пікірлер: 38

  • @matthewyim2258
    @matthewyim22583 жыл бұрын

    Watching these videos is the most fun I've had in online school this quarter, thanks for your and the other professors' effort with making these virtual labs!

  • @derikfrantz3141

    @derikfrantz3141

    3 жыл бұрын

    Glad you like them! Thanks for your message!

  • @mennaallahmo.190
    @mennaallahmo.1902 жыл бұрын

    I'm Egyptian and l study faculty of science This video helps me a lot Thanks sir.

  • @bahaaamarat6603

    @bahaaamarat6603

    2 жыл бұрын

    بيعمل ايه دا ياعم

  • @Diesel_United_LLC
    @Diesel_United_LLC10 ай бұрын

    Amazing chemistry lesson on recrystallization. Thank you for helping me understand this topic.

  • @rahulsaha8979
    @rahulsaha89792 жыл бұрын

    Thank you so much for this video. It helped me a lot

  • @Itsnotzeee
    @Itsnotzeee3 жыл бұрын

    Thank you! I study pharmacy and I was struggling to understand organic chem labs bc of online school but you made it very clear! Thank you🤍

  • @derikfrantz3141

    @derikfrantz3141

    3 жыл бұрын

    I'm happy that the video was helpful!

  • @user-ns7ng6xm3p

    @user-ns7ng6xm3p

    6 ай бұрын

    درود برادر برای پختن مت آمفتامین یه سوال دارم میتوانید کمی راهنمایی کنید

  • @prakashbishnoi6593
    @prakashbishnoi65932 жыл бұрын

    Very effective way of presentation

  • @Aldertonartco
    @AldertonartcoАй бұрын

    Yeah this does make sense. The big bag I have glows…as do bottles of LSD iv coveted in the past. Obviously not on their own I mean under UV…I bought a torch for this reason!

  • @Aldertonartco
    @AldertonartcoАй бұрын

    Can i ask, as an amateur chemist, what software that was that you could draw the box around it and connect the molecules? Im an artist and have been looking for ways to incorporate chemistry into my work….this would be REALLY USEFUL!

  • @amerhamdi5786
    @amerhamdi57863 жыл бұрын

    How extracion of cbd oil from hemp plant by use ethanol only as solvent and purefication the product ..Thank you

  • @mastercheif5645
    @mastercheif56452 жыл бұрын

    Nice video. Can I ask why you didn't filter the sample after adding the hot solvent and dissolving you product to see if there are any insoluble impurities to remove before carrying out the rest of the recrystallization?

  • @derikfrantz3141

    @derikfrantz3141

    2 жыл бұрын

    Great question. It is generally good to perform a hot filtration in case there are any insoluble materials (as you mention). In this particular experiment, I was confident that all of the material was dissolved at elevated temperature.

  • @allenhonaker4107
    @allenhonaker41072 жыл бұрын

    Does the crystalization pattern extend down to the atomic and sub atomic level?

  • @BillAnt
    @BillAnt7 ай бұрын

    At 10:00 just because a substance dissolves at room temperature, it doesn't mean that it can't be recrystallized by cooling it, or crashing it out with another solvent.

  • @marox3G
    @marox3G2 жыл бұрын

    Very good video! Could you, if it is not a problem, explain the procedure? I have kclo3 obtained from sodium hypochlorite! Thank you in advance!

  • @BearValleyPyro

    @BearValleyPyro

    9 ай бұрын

    KCLO3 is cool stuff KCLO4 is safer though if your making what I think your making.

  • @Aldertonartco
    @AldertonartcoАй бұрын

    Can I ask what those frame clamps are called and where can I get one? Or do people make them? You don’t usually see chemtubers have the frames - they usually struggle like me with portable clamps. I take it they go through the bench and are secured from below the worktop?

  • @R00K1

    @R00K1

    Ай бұрын

    They're sold as slotted lattice connectors; lab lattice supports are usually secured to the walls and floor of the fume hood

  • @Aldertonartco

    @Aldertonartco

    Ай бұрын

    @@R00K1 this makes sense - my own setup is simple and rudimentary, however, does the job. I could use a few new things but still. I have learned reagents are really everything - I don’t know why I assumed all I’d need is glassware, heaters stirrers and solvents! By this point I know iv bought quite a few fairly pointless things but also I can do what I need with what I have. At the moment at least. Also with regards my own rxns I’m running tbf I’m not sure how different the ‘glow’ under UV light is between the tryptamines im trying to produce and the annoyingly fluorescent beta-carbolines that can be the side product or full product if the temperature is too high making the reaction swing the wrong way. You know when you’ve extracted your methanol and it still REALLY glows Under UV you’ve probably gone wrong! Ha or that’s what I think haha happened. There is a name for the type of RXN but It escapes my admittedly benzo riddled brain (although I’m getting there now - it’s slow as fuck)

  • @chivoprobles3128
    @chivoprobles31283 жыл бұрын

    What will hopen if I hit epson salt en in petrolium and alcohol

  • @kieranodea771

    @kieranodea771

    3 жыл бұрын

    Nothing

  • @_satyaindra
    @_satyaindra5 ай бұрын

    Please help me 🙏 I'm confused in the distillation method, Exactly when taking pure substances I deliberately used a sample of medicine that had 5 ingredients in it, after I finished extracting it, then I filtered it and got the residue & filtrate. But I'm confused about how to separate the purity of these substances using the Distillation method, even though I have recorded the boiling points of the 5 substances, here are the boiling points: Substance A > Boiling point: 400 °C Substance B > Boiling point: 260°C Substance C > Boiling Point: 379 °C Substance D > Boiling point: 520 °C Substance E > Boiling point: 232 °C For example, if I want to get the purity of substance B, how do I do it ?? 🤔🤔🤔 Who knows, someone might be able to tell, 🙏

  • @andreimatthew1457
    @andreimatthew14572 жыл бұрын

    Group 3 present

  • @Aldertonartco
    @AldertonartcoАй бұрын

    Isn’t the DCM called the stationary phase? Can I ask what TLC plate you used? it doesn’t look like you used a glass silica sprayed plate….

  • @R00K1

    @R00K1

    Ай бұрын

    DCM is a solvent that flows through the silica stationary phase. Stationary phases don't move, solvents that move through a column or on a TLC plate are called the mobile phase. Its common to use silica 60 aluminium backed plates as opposed to making your own; this is likely what the publisher is using, best of luck with your art!

  • @Aldertonartco

    @Aldertonartco

    Ай бұрын

    @@R00K1 yes I was talking about TLC - I just messed up all the phrases of phases (look at that I’m a rapper). I annoyingly bought these massive TLC plates (200x100mm), already sprayed with silica and am usually testing tryptamines to see when a reaction is done. I do not have the money to buy more, smaller ones but I often see people performing TLC on some sort of paper (not necisarrily for tryptamines) and am just wondering what the paper TLC is used for? Can you test the same things - essentially I’m trying to understand why you need silica gel backed glass, as opposed to other times I have seen people using paper for TLC… As for collumm chromatography, it’s not something iv utilised yet but the theory is the same right? Different compounds travel through the stationary phase at different rates and therefore by running an impure sample through it - followed by solvent, the side product will seperate from the compounds you want… Pretty sure this is correct and I have learnt a little. I do know the ‘developing solution’ is different for tryptamines something like 100:25 DCM:acetone or something - that’s for TLC, not collumn chromatography

  • @R00K1

    @R00K1

    Ай бұрын

    @@Aldertonartco the backing for TLC plates isn't important usually, unless your compound reacts with it; aluminium is usually cheaper though. If you get the big 200x100mm aluminium backed ones you can cut them up with scissors or a sharp razor blade into more manageable sizes. People usually prefer using silica TLC plates as opposed to paper for three main reasons: 1. they're stronger. 2. they're usually doped with a fluorescent salt so you can see your spots under a UV light. 3. You can dip silica plates in different staining solutions to better visualize your spots whereas paper would dissolve. The solvent mixture you're referring to is your mobile phase and assuming you're running silica plates, and silica in your column the solvent mixture would likely work for both.

  • @R00K1

    @R00K1

    Ай бұрын

    @@Aldertonartco Also TLC and column chromatography work on the same principals, just different setups and use-cases

  • @Aldertonartco

    @Aldertonartco

    Ай бұрын

    @@R00K1ah ha - now THAT was the answer I was looking for! Okay yeh that makes a lot of sense. I had a feeling it would have been to do with the whole fluorescence thing…didn’t think of the fact they are stronger. Makes sense. Okay so I just bought a glass cutter and am cutting the 200x100mm big plates Into 5x smaller ones that actually fits into my beakers with watchglass on top. Thanks for explaining that - given I’m working with tryptamines, it makes sense why everyone suggests the glass silica sprayed ones because otherwise I doubt you would be able to see the results!

  • @Aldertonartco
    @AldertonartcoАй бұрын

    Would you not logically look up the solubilities of each compound in each solvent in the literature and do an excel spreadsheet?

  • @carmenhernandezmorales4934
    @carmenhernandezmorales4934 Жыл бұрын

    To complicated you make it difficult to comprehend

  • @chivoprobles3128
    @chivoprobles31283 жыл бұрын

    How is cristals method cant be recristalizte atgent two add more efedrina sodium camflued Coleman flued red phosforus sulfuric acid ramdom fertilizer whit out a littium

  • @ST-IV_858

    @ST-IV_858

    3 жыл бұрын

    Ha Dont blow it up!

  • @kieranodea771

    @kieranodea771

    3 жыл бұрын

    This is a meth purification question, you will not get answer