Receptor Tyrosine Kinases - RTK

Ғылым және технология

Hey Scientists,
today Receptor Tyrosine Kinases are in the focus.
Cheers,
Henrik

Пікірлер: 34

  • @stefanugaz
    @stefanugaz3 ай бұрын

    This was beyond helpful. 10/10 quality information

  • @debigdogk9563
    @debigdogk95636 ай бұрын

    Woooow, !!!!! thank you for so much effort in putting this great videos together. 👏🏿👏🏿👏🏿👏🏿👏🏿

  • @neurosciencegirl
    @neurosciencegirl11 ай бұрын

    Great video - thank you so much for creating and sharing :)

  • @yasserelamin9340
    @yasserelamin9340 Жыл бұрын

    brilliant explanation -- thank you!

  • @nonaiq3649
    @nonaiq36495 ай бұрын

    Thank you so much 😊 ✨

  • @darko1532
    @darko1532 Жыл бұрын

    thank you so much! incredibly good!

  • @may_mohammad
    @may_mohammad2 жыл бұрын

    Thanks alot , this was very helpful !

  • @ikbaliremalkan4315
    @ikbaliremalkan43153 жыл бұрын

    it was really helpful, thank you

  • @selin6552
    @selin65524 жыл бұрын

    Thank you

  • @saraelsayed5226
    @saraelsayed5226 Жыл бұрын

    ❤❤❤ thanks

  • @AmairaniRamirezRendon
    @AmairaniRamirezRendon Жыл бұрын

    wow super helpful!! thank you so much

  • @douaa7901
    @douaa79014 ай бұрын

    thaaanks

  • @salamabbb
    @salamabbb5 ай бұрын

    Thaaaaaanks ❤❤❤❤❤❤❤

  • @riyadmansour5237
    @riyadmansour52373 жыл бұрын

    It was, thanks a lot

  • @sirine6554
    @sirine65542 жыл бұрын

    Thanks

  • @doom_inik
    @doom_inik3 жыл бұрын

    absolut hammer! you should make a video on nonreceptor t kinases now to complement this one, or are they so similar it wouldn't make sense to?

  • @reinasleem3333
    @reinasleem33333 жыл бұрын

    Sooo helpful

  • @augustintoisoul6548
    @augustintoisoul65482 жыл бұрын

    Thank you !!!! I don't speak English but I understand this video well. The illustrations are really well done.

  • @namrasafdar4909

    @namrasafdar4909

    5 ай бұрын

    bro what r u doing rn 🙂

  • @alinamoreno9235
    @alinamoreno92353 жыл бұрын

    Wonderfully explained!

  • @jessesteven3324

    @jessesteven3324

    2 жыл бұрын

    i dont mean to be off topic but does someone know a tool to log back into an Instagram account..? I stupidly forgot my password. I would love any help you can offer me

  • @kyriedustin4619

    @kyriedustin4619

    2 жыл бұрын

    @Jesse Steven instablaster =)

  • @jessesteven3324

    @jessesteven3324

    2 жыл бұрын

    @Kyrie Dustin Thanks so much for your reply. I found the site on google and Im trying it out atm. Looks like it's gonna take quite some time so I will reply here later when my account password hopefully is recovered.

  • @jessesteven3324

    @jessesteven3324

    2 жыл бұрын

    @Kyrie Dustin it worked and I now got access to my account again. Im so happy:D Thanks so much you really help me out :D

  • @kyriedustin4619

    @kyriedustin4619

    2 жыл бұрын

    @Jesse Steven Happy to help :)

  • @ihtshamali9469
    @ihtshamali94693 жыл бұрын

    Plz make a video about ras raf pathway

  • @rahafmajdi3609
    @rahafmajdi36093 жыл бұрын

    soo helpful i just want to ask a stupid question each tyrosine phosphorylate the other one that is in front of it right? why do we use 6ATP molecules, why not just 3?

  • @henrikslab

    @henrikslab

    3 жыл бұрын

    So, RTKs are encoded by many genes in our DNA. That means we have different subfamilies (they contain different numbers of tyrosine residues in the cytosolic part -> in the video I drew just 6 but it can be even more). So depending on the subfamily of the RTK much more Phosphates can bind to the cytosolic part. To your question now: In theory 2 would be enough, right. But over the evolution, it one can speculate that it was advantageous for the genes to carry more tyrosine domains (it might be that cells and by that even animals with more domains had a selective advantage over cells with fewer phosphate binding RTKs (but since it is evolution, this is just speculation)

  • @anujagunasekera3120

    @anujagunasekera3120

    2 жыл бұрын

    I think you can also add that cell reception typically amplifies the response, this is advantageous for stuff like hormones, at the end of the day if your pituitary gland releases lets say 1000 molecules of ADH (again the number is small for simplicity sake, your gland would release millions of these) there is no way to know how many of them would actually bind to the nephrons in your kidney, however we still need to produce an adequately large response therefore the ability of a single ligand to cause a lot of intracellular change is desired, this increases the efficiency as less ligand needs to be manufactured. Does that make sense?

  • @Futurescientist_
    @Futurescientist_ Жыл бұрын

    What is GRB2

  • @vybzhub1304
    @vybzhub130416 күн бұрын

    Why did you say trinucleotide?

  • @Med-student22
    @Med-student225 ай бұрын

    Big thank to Allah then then to you

  • @bio366geethasankar7

    @bio366geethasankar7

    2 ай бұрын

    💕🙏🏻💕🙏🏻🙏

  • @rakshitatambe8627
    @rakshitatambe86273 жыл бұрын

    Thank you

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