"rewatch it if you need to" hits different the 5th time around

@ayham2000ify

3 жыл бұрын

LOOL

@fitness-rebels6136

3 жыл бұрын

Pult g guiden

@manjushreeinamdar1242

2 жыл бұрын

I swear right!!

@Radhikamorey111

Жыл бұрын

Died laughing

@beebob7136

Жыл бұрын

Haha already on my 3rd time lol

This video satisfies what I see as teaching biochems biggest misstep -- missing the forest for the trees. I get so many students that are so dialed in to specifics and miss how much easier it is to see it as a peice of a bigger picture. Nice job.

i just don't know how there's people out there that are able to break down complex mechanism into easy and digestible content like this. These people are the real smartz people in my eyes.

I have abandoned all to concentrate on your videos! Thank you. May the Lord Jesus, the Christ bless you.

@mmmmkkkk4331

2 ай бұрын

There is no God accept Allah

@mmmmkkkk4331

2 ай бұрын

لا إله إلا الله وحده لا شريك له له الملك وله الحمد وهو على كل شيءٍ قدير

for someone that struggles with this topic for years, I got it today!!! thank you

Cofactor for PDH are Tender ( thymine = B1), loving ( lipoic acid) care ( CoA = B5) for ( FAD = B2) naD ( NAD = B3 )

The cahill cycle also gets rid of ammonium ions from muscle cells that has accumulated from muscle metabolism. In the liver the amin groups enter the urea cycle.

@fook12345

2 жыл бұрын

thanks.

@esvittie8515

2 ай бұрын

Precisely

All the biochemistry videos are very very very helpful !!! 👍

A million thx for ur videos ...I m not learning for USMLE but ur videos help me a lot to get the most important info I gotta have 💛😊

amazing video man, you did a really good job of explaining that so it sticks in your head, thanks !

Dr. Ryan also once mentioned that 'Focus on the big pic first and then the details" -- Great minds think alike

would it be possible to get the glycolysis video back up?

@marydavid9473

4 жыл бұрын

yes that would be great I've been looking for it!

@monika246

4 жыл бұрын

And gluconeogenesis too

@vincefox8

4 жыл бұрын

He just posted glycolysis again yesterday!

@nganguyenthanh4952

3 ай бұрын

​@@marydavid9473😅

Can you please put the gluconeogenesis video up? You're amazing! Always struggled with Biochem :( Thank you!!

DIRTY - can we plllsss get glycolysis & gluconeogenesis back D: - a beloved patron

Thank you so much for your channel and the biochem videos 🙏

I'm studying metabolism (being an Eletrical Engineer) and found myself in a rabbit hole, now I see a light at the end of the tunnel. Thanks!

@frameshift_mutation

2 ай бұрын

Why do electrical engineers study metabolism?

@HarrydeBont

2 ай бұрын

@@frameshift_mutation Curiosity!

Best explanation I've seen on the pyruvate pathways. Thank you!

@ashypharaoh8407

Жыл бұрын

are you a doctor now

From yesterday ive been seein alot of your biochem vids. And i really wanna say im greatfull to you. Biochem was always confusing for me. Your vids helped me understand em better than i ever had. Thanks alot honestly!!

Thank you so much 😊 DirtyMed!!! Everyone needs to see this

You forgot ethanol fermentation Nice video though ❤ very clear and informative

it is mesmerizing how our body works and trick itself.

Thank you sooo very much for the greatest video 💐💐💐💐

Great overview. What about Acetyl-CoA and lipid synthesis besides just TCA cycle entry?

Too good lecture sir I am so grateful to god to provide u as lecturer

Thank you!

God bless you richly

Perfect 👌 Thank you so much

Wow, you are good! So concise

Thanks a lot. You cleared my concepts

Brilliantly explained.

Thankyou so much. This video helps me .great job

Better than the USMLE RX videos. Amazing job thank you!

@carisamclean6716

2 жыл бұрын

I agree 100%. I do not understand Rx biochemistry videos, they skip over high yield stuff

@nganguyenthanh4952

3 ай бұрын

​@@carisamclean6716😂

Thank you soooo much 🙏😊. Great job :)

Thank you very much.👏💕

Succha biochem gem you are!!❤️

I hope you make a lot of videos on biochemistry.😪😪

You're great. 🤗

Thank You ❤️

Lots of thanks

You are the best!

Thank you so much😊.

This guy has a pedagogical talent.

Can you please post gluconeogenesis. Your videos are amazing.

Lots of Thanks 😍

Thank you so much

NICELY EXPLAINED.

these videos are the best

As a layman welder, this is so fascinating, it's way over my head and I suspect my gp as well. Who does a person go to that would be able to do tests like these and see any problems associated with them?? Many Thanks!

Such a useful summary! Thank you !

Thank you

Excellent.

Best explanation

thanks you!

Thank you very much!

Great! Thank you!

Please make a video on various types of aphasia and their site of lesion

Great 😊😊

Perfect!!

any chance the glycolysis video will be posted? love your content and thanks for the step1 schedule! Best $1 i spent haha

@vincefox8

4 жыл бұрын

He just posted glycolysis yesterday!

What is the name of the reaction that pyruvate undergoes under aerobic conditions?

Minor clarification pyruvate goes into mitochondria before converting to OAA or acetyl-CoA

Do you make pharmacology videos? I need one on diabetes drugs please...

Thankyou

THANK YOU FOR THIS 😭

Brilliant

well explained, but the way to EtOH is missing. (pyruvate decarboxylase)

studying for my nutrition board exams....thanks!!

I've seen a few questions regarding LDH deficiency: NAD+ accumulation is seen and leads to inhibition of glycolysis leading to exercise intolerance.

@raahimbashir3482

Жыл бұрын

Wrong Pyruvate accumulates NAD+ is depleted Increased NADH/NAD+ inhibits glycolysis and TCA cycle , and favors lactate production

Does Cahill cycle transport Nh3 or Carbons??

I can't find the glycolysis video

great

just wondering why RBC is included in anaerobic glycolysis when technically they are Oxygen carrier :(

THANK YOUUUUUUU

LOVE YOU

Thank you so much! God bless you.

This is god’s work

Does Lactate turn back to Pyruvate when Oxygen levels go back to normal?

If someone doesn't eat carbs can they still generate pyruvate

where is the fermentation to acetaldehyde and then to ethanol in this?

Please upload gluconeogenesis too

i love you maaan you are the best

Can you, please, explain why in Pyruvate DH deficiency or in B1 def.in alcoholics, pyruvate just does not get converted into oxaloacetate by pyruvate carboxylase to keep the TCA going? 🙄

@allentristen

5 жыл бұрын

You can't keep TCA going without acetyl-CoA

@bini9462

5 жыл бұрын

I think high NADH/NAD+ ratio in alcoholics favors Pyruvate conversion to Lactate. And also high NADH/NAD+ ratio favors OAA conversion to malate so even if OAA is made from Pyruvate it may be converted to Malate right away. Acetyl coA is available from beta oxidation but there is depleted Oxaloacetate stopping the TCA cycle. Correct me if I'm wrong

@bini9462

5 жыл бұрын

And one more thing, in PDH deficiency the problem is not OAA deficiency but acetyl coA deficiency not getting made from Pyruvate specifically from glucose. To make up for it acetyl coA must be produced from fats. That's why high fat diet and ketogenic diet with low intake of carbohydrates is the treatment for PDH deficiency to make acetyl coA from beta oxidation so as to continue the TCA cycle.

@nganguyenthanh4952

3 ай бұрын

😂

Mistake that should be corrected The muscles have stored g6p but cannot be converted to glucose that is because muscles lack g6 phosphatase.. So it is g6p that is converted to alanine not glucose. Because if that was the case why would muscles convert its glucose to glucose again. Correct this mistake plz.

Op bro

I would love to buy you a pint saving my grade in biochemistry

Can you put arabic translation please. Watching you from Iraq

The name pyruvate suggests that it could burst into flames at any point in time and make man into a pyre.

7:11 CAHILL CYCLE 8:50 Cahill cycle full schema

where is the gluconeogenesis video?

Fabulous - You have a God gifted ability too ahah

Thanks dirty

1

Seriously....it is this simple ??

monetize

Not carbon molecules, carbon atoms.

@DirtyMedicine

4 жыл бұрын

irrelevant for clinical purposes, but you are correct

@nganguyenthanh4952

3 ай бұрын

​@@DirtyMedicine❤

Thank you!

Thank you!