Preventing and treating dementia with diet - long version (~40 minutes) with commentary.
Ғылым және технология
In this Low Carb All-Stars presentation, Dr Paul Mason discusses that the risk of dementia can be significantly reduced with attention to nutrition. Furthermore, symptoms of dementia can be also be improved in those already suffering dementia. Surprising findings include the link between brain size and obesity, how the brains of those with dementia are insulin resistant and cannot effectively use glucose and how ketones can circumvent this issues. Data on the true risk of the APOE4 gene is also presented, with the conclusion that lifestyle is more important than genetics. Professor Peter Brukner and Dr Paul Mason provide commentary on future directions for research at the conclusion of the lecture.
Пікірлер: 105
This is pure gold I never get tired of Dr Mason's videos! Amazing!
@Hnaljdv
3 жыл бұрын
Same here!! It's the third time I'm listening to this one haha
I picture a mic drop at the end of every one of Dr Masons presentations. Thanks again Doc. Love your work.
Dementia is the top health concern for so many people in the UK because the institutional health care here is appalling- from NHS to care homes. Inhumane, cruel and sadistic. I would never want to be very sick or grow old here, you will be put on an assisted pathway plan before you're even diagnosed.
@tobykelsey4459
3 жыл бұрын
Indeed. DNR without consent or family discussion is getting more common.
@gomogo2000
3 жыл бұрын
Assisted Pathway Plan. Sounds ominous...
My mother in law has dementia. My wife who is 55 is worried about getting it. I have switched to a high fat low carb diet trying to lead by example. Ive lost 24 lbs feel great jump on my trampoline outside 150 times and walk it off. Im 69
@ruschev2
3 жыл бұрын
good job boomer. go gluten free, it will save your brain too
Either I've got dementia or I already saw this vid...
@nathansmith6914
3 жыл бұрын
Haha me too.
@JosipRadnik1
3 жыл бұрын
@@nathansmith6914 what vid?
@jimmyhvy2277
3 жыл бұрын
Who said that ?
@ellenorbjornsdottir1166
3 жыл бұрын
:D
Dear Dr Mason, as a double APOE4 person, and someone who has been caring for her dad (advanced vascular dementia, and must have at least one copy of E4) for the last 5 years, I am so grateful for this video. My dad and I, have been low carb for a year and a half, but in the last 3 weeks we have been on a ketogenic diet, and there have been improvements in my dad's speech. Now dieticians wish to feed him bananas to get his weight up, even though his GP did his bloods about 3 months ago, and they were all good. The dietician has now got social work to investigate, under a care and protect order (in Glasgow, UK) I am devastated that after my dad's improvements, we will be forced to feed him sugar.
@Chahlie
3 жыл бұрын
My siblings feed our mother huge amounts of sugar ("because she likes it") and her memory is lousy and she is irrational. Sugar ought to be banned.
@prins424
2 жыл бұрын
That's terrible. How are things now?
I would love to see you talk about histamines and DAO.
Thank you Definitely keto and carnivore helped me fix my irregular periods. I had PCOS and infertility so I went through infertility treatments twice for my two kids spending massive amout of money. I really wish I had known about these diets in my 20s. However, I am just glad to know now to fix my period.
Fantastic information and well delivered as always. Thanks, Paul 👍
Awesome presentation Paul. Many thanks for all your hard work.
Thanks for the presentation Paul. Also interesting about the discussion at the end, especially about autism.
This a life changing lecture. Thank you!
Thank you Dr. Paul Mason. You have opened my eyes. I am striving to remain on a Ketogenic diet lifestyle and to have my whole family- children, grandchildren, siblings, friends and relatives to move to a Ketogenic diet and experience the health benefits. I pray that God hears my prayers. God bless you and all the doctors involved in your efforts to make this world a healthier, happier and safer place to live in for generations to come.
Nice presentation....good summary ....thank you Dr Mason
Great job Dr Mason. Thanks for another amazing presentation. Any link to the slides and references??
Great lecture! Thank you for sharing this precious content with huge new information!
Great talk as always! I noticed that you missplaced the titles of omnivores and vegetarian diets on the AGEs - slide, so I used your reference and downloaded the study. It was a very interesting study, and what struck me was that the omniveres (traditional) was obviously EATING more AGEs than the vegetarians (alternative), yet there were more serum AGEs present in the vegetarians. How is this? The study concluded it was because of fructose. Can you perhaps even make a video on this topic? Is it possibly so that our guts deal with ingested AGEs and they only are a problem when they occur in the blood?
Thanks Doc, been looking forward to seeing this
I appreciate your work so much! 🙌🏻👊🏻👊🏻👊🏻👊🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻
Thanks for the talk.
Excellent info. Thank you.
Great lecture. Thank you. With you on the autism link. While the body does its best to compensate for a bad diet, it's easy to imagine how hard it would be to grow the perfect human baby with rubbish ingredients. Keep up the great work.
Thankyou so much for this talk.....very very informative
This presentation is incredible (in the good way). Thank you so much.
We love you Paul
Dr Mason, can you share more info about BHRT for women/estrogen levels and brain health? You have piqued my interest as an APOe3/4.
@eugeniebreida1583
3 жыл бұрын
51% of our society require knowledge of maintaining essential hormone levels til death. (estrogen/testosterone)
does it make a difference whether the unsaturated oils have been oxidized (before consumption)?
Yes, dementia is my greatest fear now I’m getting older.
Excellent 👍
Thank you I have to Apoe4 one copy I'm 62 my mother lives with me shes 91 and has the Apoe4 gene and has dementia.
Alpha Lipoic Acid is also very interesting research.... For Alzheimer's diabetes and more...
Dr. Paul can someone get dementia that doesn't have the Apoe gene?
@museitup4741
3 жыл бұрын
Yes
I went to see those RCT's comparing LF vs LC but I saw less than 3 where the protein was matched and in those, the difference in weight loss was not different.
There is a condition called MCAD which i have. Keto high fat made me so.ill I nearly died because i cant breakdown fats due to a genetic metabolic disorder which causes blood sugar to fall so low you can go into hypoglycemic coma
Dr. Mason is really tiny He's so cute!! 😂 But seriously, thanks for the amazing information!
4:24 Colour of alzhiemer brain is noticeably browner. Is this just down to the samples used - or is the Maillard reaction in play? (oxidation/ seed oils )
17:11 May I suggest an edit. “... even more so if you have ‘poor’ blood sugar levels”. To ‘elevated’ or ‘poorly controlled’ or ‘poorly managed’ however controlled or managed may lean towards the absolution of responsibility for the “healthy” non diabetic, normal adult, active teenager etc. I would like to hear this better applied to everyone in the community ... “poor” is a word that may lead to interpretation as “low” when I believe we are intending to mean elevated. (Just a thought) 🥰 Paul! “... bad” ? 17:20 🙄
@eugeniebreida1583
3 жыл бұрын
Important distinction, thanks!
@lorettadillon-ham1574
3 жыл бұрын
@@eugeniebreida1583 🥰
Thank you. The difference between pufa's in processed seed oils and in meat, fish, and eggs may be the fresh meat fish and eggs keep oxidation to a minimum.
How do vegetarians and vegans fare. That would be an interesting study.
@T-aka-T
3 жыл бұрын
Badly, as he says here and elsewhere.
@florrie8767
3 жыл бұрын
I know 2 or 3 vegans that lived to 90s but they ate very healthy diet
@thighdude7
3 жыл бұрын
It is both low carb and minimizing 'vegetable oil' consumption that are needed...
لايوجد ترجمه الرجاء اتاحه الترجمه باللغه العربيه
Thank you! It makes me sad when I think of loved ones who suffered and died because of a poor diet that was encouraged by the government and the AHA.
💚
I don't understand...when I googled nigerian food i found is made up mostly from carbs, not even carbs and something else. Can someone who leaves there give more details?
@ellenorbjornsdottir1166
3 жыл бұрын
It's relatively (not absolutely) low in seed oils
Wow
N + 1 my mum was a gestational diabetic. I was 10.5 lbs and have dyslexia and on the spectrum
No matter what my diet I cannot raise HDLs or lower triglycerides. They been stuck in the same place for decades regardless of diet.
@tjellis1479
3 жыл бұрын
what are the LDL numbers?
@rctempleton9711
3 жыл бұрын
i was on keto switched to nuitarian try eating five pounds of walnuts it worked for me what do birds eat their healthy omega threes are like 12 percent of. your brain just. eat natural
@paulasamec8715
3 жыл бұрын
Green Deane It takes a lot of time to get rid of the havoc that seed oils- the ones which make you fat - are replaced with enough healthy saturated fats in your cells ( membranes ), up to 2 years, see Dr. Paul Saladino
@florrie8767
3 жыл бұрын
My triglycerides were normal.on plant diet but went high on more animal food diet
@eugeniebreida1583
3 жыл бұрын
@@florrie8767 that sounds logical to me. I am an omnivore who leans toward vegetables. But I do need calories in order to keep my weight, and animal meets provide decent calories and extra fats for that purpose. If I didn’t need more calories, I think it would be healthier to have very small amounts of meat, ideally at each meal, as one grows older
Great news, I'm on the carnivore diet and liking it.
Dr Mason, can you get the same results with exogenous ketones? Because it might be hard to get people to change to a keto diet, especially if they have dementia.
@greenfield1944
3 жыл бұрын
according to Dr Ken Berry, no you just can't gulp down some exogenous ketones and get the benefits of the ketogenic diet.
@scotchfillet
3 жыл бұрын
@@greenfield1944 exogenous ketones can be used by the brain.
@nathansmith6914
3 жыл бұрын
@@scotchfillet Dr Boz had a video showing that but I don't know if it was as good as the keto diet. Still, you'd be mad not to do it.
@T-aka-T
3 жыл бұрын
The hardest thing to tackle is nursing home and hospital food. Shockingly non-nutritiious. So exogenous ketones may be better than nothing--maybe. I am guessing here, of course. However, the carb damage (high glucose) will still be occurring, so insulin levels will still be high despite the ketones (because the presence of ketones was not a function of deprivation of carbs). So maybe worth a try, but better to feed them real, fatty meat, meat and more meat 🥩 🥩 🥩 (not grey stew, peas and mashed potatoes followed by dessert).
Interesting video thank you. Chronic disease seems more often than not attributed to diet, or thought to be preventable, or even reversible by diet. Many individuals would have difficulty following a challenging long term low carbohydrate diet. It seems inappropriate to offer this type of solution as a practical treatment.
@T-aka-T
3 жыл бұрын
Ian, on the contrary, it's the easiest diet to follow! Never hungry, top quality nutrition. What's to miss about empty carbs?? And in any case, why would a doc FAIL to recommend it as "impractical" when the alternative low fat high carb habit is making you sick? Strange comment to make.
@eugeniebreida1583
3 жыл бұрын
@@T-aka-T Certainly the only alternative diet is not ‘high’ carb ‘low’ fat. My 92 yr old cogent active hwp dad (and all of us eat approx 30-30-30 fat-carbs-protein. (plenty of green veg/onion family/berries etc)
Someone tell Joe Biden’s handlers about this.
@beau5296
3 жыл бұрын
🤣🤣🤣🤣🤣
@t.c.s.7724
3 жыл бұрын
Haha. Cruel and hilarious comment.
@ellenorbjornsdottir1166
3 жыл бұрын
He already knows. That's why he's just muddling, rather than Donald Trump who is mercurially demented
@bibingraj9743
3 жыл бұрын
😅
@beaubolinger1521
3 жыл бұрын
@@ellenorbjornsdottir1166 You are absolutely a brilliant person--So highly educated I am sure
In a study of more than 1,200 people, researchers show that individuals with higher levels of saturated fats in their blood are more likely to develop dementia, including Alzheimer's disease.21 Apr 2021
So, I'm thinking this is why a high sugar diet affects memory so much...the insulin is so busy elsewhere, or something. I wonder how many older people are secret sugar eaters. I've heard stories of some doing almost anything to get their hands on it, and the consequent irrational behaviour.
Scientists who dont publish results they dont like are liars to me, not scients! Thx Paul from Munich
who eats oysters and black beans ? Aussies do it ?
The beta-amyloid monomer looks like a Christmas stocking, at least in this graphic.