Potency Testing & Instrument Configuration

Ғылым және технология

Presented By: Chris Leija, PhD, Hillel Brandes, PhD, Tricia Schnulle
Speaker Biography:
Chris Leija, PhD: Chris Leija is a Senior Scientist supporting the development of small and large molecule certified reference materials.
Hillel Brandes, PhD: Hillel Brandes holds a Ph.D in biochemistry and is an Analytical Technology Specialist supporting analytical customers within the Applied Solutions Group of MilliporeSigma in North America.
Tricia Schnulle: Patricia Schnulle obtained her M.S. from the University of Illinois with a research focus on reproductive immunology.
Webinar: Potency Testing & Instrument Configuration
Webinar Abstract:
Rapid gradient method optimized for 17 cannabinoids using HPLC-UV
(Presented By: Chris Leija, PhD)
Let's talk instrument configuration for an ideal LC method
(Presented By: Hillel Brandes, PhD) When planning for new method development, an initial consideration should include what instrument is available or intended to be used for the experimentation. This will impact options regarding choice of analytical column. Conversely if a specific type of column is intended, this will influence what instrument is best paired with the column. Given those choices, what follows are other considerations regarding instrument configuration to optimize the chromatographic performance of the selected column. While method development generally addresses aspects of the actual analytical method, this talk will highlight due consideration of optimum instrument configuration to achieve the best chromatographic performance.
High Purity Water: Hints and Tips for Cannabis Analyses
(Presented By: Tricia Schnulle) Ultrapure water is highly prone to contamination, e.g., it easily leaches contaminants out of container surfaces and absorbs contamination from the laboratory environment. As ultrapure water is the most-frequently used solvent in any LC-MS laboratory, its purity plays a critical role in analyses. There are a number of high-purity water handling pitfalls that result in degradation of its quality. To help analysts critically evaluate the potential risks involved in poor ultrapure water handling, we will discuss the effect of laboratory environment and long high-purity water storage, the effect of the container material used to collect ultrapure water, the effect of laboratory ware and equipment cleaning, and the effect of poor practices of water purification system usage.

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