As for Metoclopramide, it is also said to block 5HT3 receptors to some degree (antagonist). Interestingly, the mentioned increased gastrointestinal motility is initiated through the stimulation of 5HT4 receptors (agonist), which lead to a release of acetylcholine. Very good video, thank you!

I am 27 and a stroke survivor I find your videos extremely helpful. I have ataxia. I find that when I

Make more videos on pharmacology please...it will be helpful.

@arikeghumman5246

Жыл бұрын

😂

@arikeghumman5246

Жыл бұрын

Which year now sir or what you are doing now

Absolutely love the explanation of N/V. Straight to the point.Thank you.

Hi Armando; amazing video thank you. I am an advanced practice paramedic in the UK currently doing a prescribing course and this was really helpful. Maybe a little more info on the pharmacokinetics e.g. absorption, elimination and half life etc would have been extra amazing too...although I get that this is not where you were pitching this. Thanks and keep them coming.

The cause of motion sickness is not limited solely to the inner ear. It's because the different organs which we use to determine our position in space (inner ear, eye and cerebellum) sometimes send incompatible information to higher centers, resulting in nausea. That's why sitting in the front of the vehicle helps with motion sickness - because then we see the road moving in front of us, which is more in line what our vestibule and cerebellum pick up on.

Would love a updated video that includes Neurokinin-1 Receptor antagonists (Substance P antagonists) like aprepitant, fosaprepitant, netupitant, etc. Great video!

Great video. This was perfectly designed and executed.

You are such a life saving angle. Keep up the good work sir

Amazingly explained!! You are doing a superb job👏🏻👏🏻

You probably should've mentioned this small detail regarding the medulla oblangata since it's pretty high yield: not only does it contain the vomiting center, it is also the reason why alligators are ornery (despite what mama says).

Sir ,you are a very good teacher.

never understood antiemetics and vomiting so well before! thanks

I've experienced hyperemesis with all my pregnancies, currently my 3rd pregnancy and this was surprisingly the 1st time antiemetic medication helped at all.

amazing illustration and explanation. keep up the great work!

Fascinating. Our own bodies produce an effective anti-emetic, from one of those glands in the neck area. You can test it out by taking little sips of something that really "doesn't agree with you". When your body tells you either to stop or to throw up, ignore it and carry on. You'll feel something flow into the back of your throat which will quell your need to vomit. It has quite a distinctive taste, which I can't really describe, but pleasant. I understand it's a very functional thing for other species, though it rarely comes into play for us. Have a bucket handy if you try this experiment.

Marvellous effort Sir !! Keep it up ... My many concepts are clear now ..

You’re amazing sir , love your diagrammatic explanation ❤️❤️

I will have my Oral revalida next week and this video makes it easier for me to remember all about antiemetics.

in the vomiting center, there are other several receptors like serotonin receptor cause if the vagus nerve transiting the serotonin signals it makes sense that it is only can attach to serotonin receptors but overall this was an amazing video thanks so much for your hard work

You are amaaaaaaaaaaaaaazing !!! Thanks from the bottom of my heart, you really helped me a lot with this useful video

thank you for this great video. It is covered a lot in the short time

You have lovely ability! Thank you so much

*Chlorpromazine 😊 Thank you for making concepts easier, making me understand things I couldn't quite understand from my books ❤️ right when finals are around the corner 😂

@icebreaker9006

2 жыл бұрын

Obey Jesus Christ or you will go to hell, turn to the Lord before its too late, if you don’t REPENT OF YOUR SINS then you will likewise perish in hell. All liars, fornicators, adulterers, idolaters, blasphemers, whoremongers, thieves, murderers, homosexuals, effeminate, etc, will not inherit the kingdom of God. Once you turn to the Lord, read the new testament in the bible, the gospels, to develop a relationship with God. God bless you all. Turn to Jesus, repent or perish, turn or burn.

Thank you so much you make med school survival seem so easy 😍

Great explained....great job sir

you are a guru mehn...i can kiss u a billion times...u just made my day! make more videos on any health conditions and pharmacological approach...thanks a lot!

i love to learn !! best feeling in the world, and it's free!!!!

@ramaos8542

3 жыл бұрын

Yes!!!

that was amazing, keep doing what u do ♥ thank you

Thank you so much for this video. We were just taught this topic in class, I forgot to bring along my book to review, so I was super happy to see this uploaded, helped alot.

We need an antibiotics video next! 😁

@Jedfer84

6 жыл бұрын

Already done my friend. kzread.info/dash/bejne/e4p2pdSzmrLSZJM.html

@egonjankowski3587

6 жыл бұрын

Afiq Syahmi uiii

Bro.. am a huge fan for you.. please explain pharmacology of antileprotic drugs

Beautiful information ma man, good job. Keep up the good work.

Thank you....when i saw my textbook, it was looking so confusing, now it has become easier..💜

Thanks Armando for a great video! One question; in the part about the vomiting reflex you say that one of the symptoms of the reflex is a tachycardia. Should't that be a bradycardia because of the vagal response when the vomitingcenter is triggered? Thanks again! Greetings, Jaap (the Netherlands)

Thank u very much for ur help sir. This is very important . Thanks again. ❤ From Srilanka 🇱🇰

This was nice and was pretty much just like what's in my notes, so thank you!

Awesome explanation. Thank you

Great video 👍very helpful

Thank you so much for making this wonderful video ...it is really helpful 🌺

Thank alot sir for all the videos you made cology so easy and Interesting... 😇

U r the best. U cleared all my doubts

ahhh pathopysiology plus pharmacology best video ever made

Amazingly explained 💯

It is so helpful....and make concept much clear...thank you sir

Great job thanks so much

Excellent lecture! Never saw anyone make barfing look so fascinating and artistic! I'm serious. If you can do that for this topic, you can do it for anything,. Fantastic job 🙂.

The best video for nursing students. just wondering the physiology of self induced vomiting

Thank you sir ...🙏🙏🙏 Amazing video .. ❤❤❤

amazing video, thank you

Thank you for the video as it was very helpful to understand. You mentioned that Ondansetron is not recommended for 1st trimester, why? What could be the side effect to the fetus?

Great video

Very good video, thank you

great job.... thanks for this vedio...☺

Awesome! Ready for rotation tomorrow ;)

This is so helpful!!! Thanks a lot!! Keep up that great job :)

What aweasome explantion 😍

Please do make a video on laxatives....Love your videos...very helpful...thank you

Thankyoou so much Armando , you are the best teacher (Y)

It is a great video. really made it easy and simple to understand and perfectly designed.

amazing teaching way

Thanks , you are a great

You made it so easy thank you so much

جزاك الله خيراً 🤲

Thats ultra perfect thank u so much 😭😭

thank you sir !! ur amazing

This was the best!

Great work thanks

thank you for this, I know understand the physiology of emesis and the basic pharmacology of anti-emetic drugs. 😊⭐

This is amazing

Ur videos are very clear tnx 🤩

This video helped me so much ! Thanks alot :D Please can you make a video about Anti-anaemia and Haematinics!

video is really nice. but please give the mechanism of action of prokinetic drugs like metoclopramide , dompirodone. u gave details about CNS effect hw it acts on g.i. please elaborate.

Great video sir.. Thanks.. Sir can u share some knowledge about CVA topic if possible plz!! Thanks alott sir

you are brilliant.....

I think the vestibular apparatus doesn't go through the CTZ but via the cerebellum and activates the Vomiting Center

Thank you very much

You are king 👑 of pharmacology

thank u so much.....such a great video....sir can u plese make a video on congestive heart failure pharmacology

Thank you so much

Thanks a lot u r always great

Thanks for Great video

Pronunciation may differ..BT explanation was grt sir..thank uh sir🙏

Excellent!

Thank you!

Amazing experience sir but we need more videos

thanks for this short lecture 😎🙌

So helpful...thank you

great video

Thank you 🙏🏻 ❤

question: so If vagus nerve carries the message from stomach using 5ht, the vomiting centre does not have 5ht receptors, the ctz has the receptor for 5ht. you did not say if vomiting centre communicates with ctz, you said ctz relays info to vomiting centre? please explain? how does 5ht will cause vomiting reflux if vomiting centre has musicraic receptors?

Can I ask you where dexamethason, canabinoids, benzodiazepines and NK1 receptor antagonists act? My professor told us they are anti emethics too but he didn’t say where their action was...Anyways thanks a lot, the video is clarifying!

Thanks

thank you so much it helped alot

So good, you should give more examples drug, thankyou

Great video........ Thnk u so much.......

Thanks!

Thank youuu very much Can you add the summery part at end of the video ?

Thanks a lot sir..😊

Where can i find this paper complete as it's a good summary? ❤️