Peptide Bonds and Naming Amino Acid Sequences
This video introduces peptide (amide) bonds in the context of protein formation. It also discusses naming conventions for peptide chains. This video is meant to supplement CHEM 113 - Intro to Biochemistry at Central Washington University.
Пікірлер: 14
Exactly what I'm looking for! Hope this helps to other students as well. 🎉🎉
This channel needs more views! Thanks for this!
omg amazing, no one can teach better than this. keep doing the videos constantly. it may take slow but once it is in track you will win
A life saver thank you
That helped me a lot thanks!
@elikemprecious
Жыл бұрын
😊
Thanks for this wonderful lecture, but I'm a bit confuse. In dipeptide OH remains at the end but in tripeptide only O remain. Why
@grocechemistry7966
8 ай бұрын
Whether or not the C-terminus end has an -O or -OH will depend on the pH of the solution it's in. The H in the carboxylic acid is an acidic Hydrogen, so it will be donated to the water (or to an amine end of the amino acid) in the solution under neutral circumstances. So, I was just being inconsistent with my convention. At normal body pH, it would be the -O (with a negative charge due to the loss of the H).
What happens with glutamic or aspartic acid T_T
@grocechemistry7966
27 күн бұрын
Aspartic acid is also called aspartate, so the -yl ending is added to that form: aspartyl. Same for glutamic acid, also called glutamate, which becomes glutamyl when it's a residue.
@crimsonrealm7
27 күн бұрын
@@grocechemistry7966 for glutamate, then wouldn't it be same with glutamine? Glutamate = Glutamyl Glutamine = Glutamyl
so we will just put -yl on every end except for the c-terminus? i thought oligopeptides are 2-20 amino acids and polypeptides are what makes proteins since polypeptides are 50 or more amino acids and proteins have 5p or more amino acids.
@grocechemistry7966
2 ай бұрын
Yes on the naming! As far as the classifications, I've seen a variety of definitions based on the application. I've learned oligopeptodes were up to 10 amino acids (including the di- and tri-peptides and all the specific lengths leading up to it). I've seen it as 2-20 amino acids. I think it's just about context as to how specific you get with the language. Polypeptide usually has the meaning of something larger, on the scale of an entire protein, but there's lots of wiggle room in between.
@impotassium
2 ай бұрын
@@grocechemistry7966 thanks