Pattern Recognition Receptors

We've already introduced pattern-recognition receptors, which recognize PAMPs and DAMPs, but now let's go over the specific types, and how they work. How many Toll-like receptors are there and what do they recognize? What are the adaptor proteins that kick off their signal transduction pathways? What about NOD-like receptors and RIG-I-like helicases? So much to discuss!
Script by Stephanie Melchor
Select images provided by BioRender.com
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Пікірлер: 57

  • @fazergazer
    @fazergazer2 жыл бұрын

    I’ve worked on TLR family proteins in my research. This is an accurate and concise introduction, I hope as many researchers watch it. Isn’t this system beautiful? Thanks!

  • @anwaraltamimi3592

    @anwaraltamimi3592

    2 жыл бұрын

    It is!!!

  • @user-vu9st6fd7v

    @user-vu9st6fd7v

    Жыл бұрын

    Awesome!!

  • @RobertoCighetti
    @RobertoCighetti2 жыл бұрын

    I did my thesis and my PhD on TLR4! 😍 Really loved this video, concise but very informative

  • @indiabiologyexplains5013
    @indiabiologyexplains50132 жыл бұрын

    This video was probably one of the most useful lessons on biology I have ever had. Thanks for teacher thousands of more like me and continue what your doing!

  • @yes7855
    @yes78552 жыл бұрын

    Beautiful and completely kept my attention the whole way! Thanks for being a blessing, lovely team ❤️❤️❤️

  • @abeerabu-eisheh5395
    @abeerabu-eisheh53957 ай бұрын

    OMG How smooth you explain every single point!!👏🏻👏🏻 You are so talented 👌🏻

  • @santicruz4012
    @santicruz40122 жыл бұрын

    The amount of content you put up is incredi le

  • @alashikbillah4096
    @alashikbillah40968 ай бұрын

    You are a saviour to the medical students like me 🙏

  • @mahinvasavada2992
    @mahinvasavada29922 жыл бұрын

    Clear, simple, perfect.

  • @evelin5255
    @evelin52552 жыл бұрын

    thank you for helping me with my bachelors thesis in immunology :')

  • @user-margaritasourri
    @user-margaritasourri2 ай бұрын

    My master's thesis is on TLRs, thank you for this video, it is very informative!

  • @user-vu9st6fd7v
    @user-vu9st6fd7v Жыл бұрын

    U r truly AMAZING Prof. Dave❤️‍🔥

  • @sciencenerd7639
    @sciencenerd76392 жыл бұрын

    It seems to me that bacterial flagella are more corkscrew-like than whip like. That is, bacterial flagella spiral while eukaryotic flagella whip (if I remember right). In any case, this is an amazing, fantastic video, and I tremendously appreciate your work!

  • @-JA-
    @-JA-2 жыл бұрын

    Thank you.

  • @imtiredofitallmakeitstop
    @imtiredofitallmakeitstop2 жыл бұрын

    thanks dave

  • @sciencenerd7639
    @sciencenerd76392 жыл бұрын

    thank you

  • @mohamhashem331
    @mohamhashem331 Жыл бұрын

    thank you sir you rescued me

  • @davidsweeney111
    @davidsweeney1112 жыл бұрын

    Interesting theory

  • @blocksbrains4911
    @blocksbrains49112 жыл бұрын

    I love listening to this rich knowledge in comparison to the flat earth vids. You are a good man.

  • @NovaWarrior77
    @NovaWarrior772 жыл бұрын

    bless you bro

  • @michaeldob2153
    @michaeldob21532 жыл бұрын

    great vid! My question is since DAMP's are associated with Cell damage. Is a local limited hyperkalema kind of DAMP too?

  • @SCIPROlearning
    @SCIPROlearning2 жыл бұрын

    Great 👍👍👍

  • @sauhardshrivastava7456
    @sauhardshrivastava74562 жыл бұрын

    Just one issue, MDA5 senses dsRNA and not dsDNA... Other than that it's perfect

  • @samirdileep
    @samirdileep4 ай бұрын

    What about TLR-8? What does it bind to?

  • @vimpirani1680
    @vimpirani16802 жыл бұрын

    Tell me about antimatter

  • @fusionhypnotic
    @fusionhypnotic5 ай бұрын

    blows my mind how complex we are

  • @probabiltywave7582
    @probabiltywave75822 жыл бұрын

    I have a hypothetical question not related to this video. Assume we have a small pressurized container that holds the same amount of air atmosphere on planet earth. If we open this container on earth till empty what will happen to earth air pressure ? Will the atmospheric pressure double or will remain the same and the extra air will escape earth gravity ? Don't know how to handle this hypothetical problem. Hope you could guide me.

  • @probabiltywave7582

    @probabiltywave7582

    2 жыл бұрын

    @Wh•a•t•sap÷❶❷❸❹❷❸❶❹❶❸❻ where can I find him ? Sorry not familiar with the name.

  • @ArveEriksson
    @ArveEriksson2 жыл бұрын

    Gee whiz, I learn stuff about my job by going to KZread U. What a society we live in! Completely unrelated tangent: In Sweden, some decade(s?) ago 'damp' was used as some type of slur against people with ADHD. I have bugger-all idea why. (On a side-note: I get ads from ThermoScientific on this video, and I love it.)

  • @Carlosk12
    @Carlosk122 жыл бұрын

    Sees an oval inside any figure Me: AMOGUS PATTERN RECOGNITION

  • @bigbeans202
    @bigbeans2022 жыл бұрын

    Hiya Dave, love the vids. Would love to see some computer science videos!

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    2 жыл бұрын

    I'll get to that eventually! I want to do all kinds of engineering, including electrical engineering first, so that I there is no gap when discussing computer components.

  • @masternobody1896

    @masternobody1896

    2 жыл бұрын

    @@ProfessorDaveExplains can you make more video about immune system

  • @masternobody1896

    @masternobody1896

    2 жыл бұрын

    @@ProfessorDaveExplains why does cancer form and how to destroy cancer?

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    2 жыл бұрын

    This is a whole immunology playlist so there will be many more. As for cancer, start with my biochemistry tutorial "what is cancer".

  • @bigbeans202

    @bigbeans202

    2 жыл бұрын

    Awesome! So glad you'll get to that. I'm currently doing my Major in CS :)

  • @bhaktithakur2185
    @bhaktithakur21852 жыл бұрын

    Can extracellular ss rna indicate damage to tissue cells ?

  • @indiabiologyexplains5013

    @indiabiologyexplains5013

    8 ай бұрын

    They could. But some RNA is used in cell to cell communication.

  • @sadbois4546
    @sadbois45462 жыл бұрын

    I would love merch lol idk why. 😂

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    2 жыл бұрын

    Check out my store tab!

  • @sadbois4546

    @sadbois4546

    2 жыл бұрын

    @@ProfessorDaveExplains Thanks!!!

  • @whatsagoodusername823
    @whatsagoodusername8232 жыл бұрын

    Unul pentru algoritm

  • @anandkishor2791
    @anandkishor27912 жыл бұрын

    Hyyy

  • @HarryTheLoser_
    @HarryTheLoser_2 жыл бұрын

    :)

  • @1.4142
    @1.414210 ай бұрын

    RAGE

  • @Nesteate
    @Nesteate2 жыл бұрын

    What if the reason he knows so much is, HE IS JESUS

  • @nurphurecarnium

    @nurphurecarnium

    2 жыл бұрын

    Ironic since he is an atheist 🙃

  • @IsaacAwad.04
    @IsaacAwad.042 жыл бұрын

    Why do u stopped showing your self talk in the video ? Like I dont mind but you did that for so long. haha ok bye thx.😊

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    2 жыл бұрын

    I don't have access to KZread studios anymore, where I used to shoot my content, so I can't do what I used to do with a nice camera and green screen. So I do audio only, except for my debunks where I use my webcam.

  • @IsaacAwad.04

    @IsaacAwad.04

    2 жыл бұрын

    @@ProfessorDaveExplains np I still understand everything you teatcher thx dave 😁

  • @ju_2076
    @ju_20762 жыл бұрын

    The earth is flat