Pathophysiology of Diabetes Mellitus
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Description of pathophysiology of type 1 and type 2 diabetes, and a discussion of complications.
PLEASE help me improve these videos! Take this quick survey about how the videos help you learn: goo.gl/BjU8bk
Description of pathophysiology of type 1 and type 2 diabetes, and a discussion of complications.
Пікірлер: 280
Mr. Wolf.. You are the sole reason why I am passing Patho right now. I don't even listen to my teacher in class. I jot down some notes of diseases and processes that we cover, and then when I get home...I pray to god that you have covered them in a tutorial! THANK YOU!
@HealthEdSolutions
3 жыл бұрын
Thanks for the feedback!
I'm so thankful for all of your videos. It's like going to class without having to leave my room. I've learned so much.
@HealthEdSolutions
3 жыл бұрын
Thanks for the feedback! We will be rolling out new lessons soon. Keep watching, we appreciate the support!
You are a great lecturer and easy to understand. Wonderfully helpful explanation of the pathophysiology behind diabetes. I am a 2nd year nursing student your videos are really helping me. Thank you.
Thank you so much for such a simple and thorough explanation. I just wish you were my instructor for all of my classes! Thank you again.
Thank you so much! I have an exam on the endocrine system today in Pathophysiology and you have made DM so much easier to understand. Wow!
@HealthEdSolutions
3 жыл бұрын
Thanks for watching!
You are very good at explaining this. I didn't feel like you were talking over-my-head, so I was able to enjoy this video and come away with a really good understanding of the material. I really appreciate that!
@HealthEdSolutions
3 жыл бұрын
Thanks Robin!
Just wanted to say I love these videos, they are so helpful to me as I go through nursing school!
@HealthEdSolutions
3 жыл бұрын
Thank you! Glad they were helpful!
I always have difficulty understanding Type 1 and type 2 diabetes especially in-depth of pathos. Watching your video makes it so much easier to understand and fun to watch. Thank you so much for your great videos.
@HealthEdSolutions
3 жыл бұрын
You’re welcome. Glad you found it helpful!
This is very well, and simply explained. Thank you for the video.
Just watched this 10 years after you posted, thanks
Great lecture Dr. Wolf. You are really helping by uploading these videos.
@HealthEdSolutions
3 жыл бұрын
Thanks so much!
Mr. Wolf great lecture and explanation for the DM.. Plus the expected outcomes of both are an added bonus!! Cellular K and serum differences are awesome!! Thank you
@HealthEdSolutions
3 жыл бұрын
Thanks Conrad!
thank you! your videos are always helpful from my A&P classes and now nursing classes
@HealthEdSolutions
3 жыл бұрын
You’re welcome. Glad you found it helpful!
Great Video explaining Diabetes Mellitus watched them several times before taking my test in this system this was so helpful thank you!
@HealthEdSolutions
3 жыл бұрын
Thank you for the kind words!!
Thank you so much for posting these videos. I feel a lot better about taking Patho this coming semester.
@HealthEdSolutions
3 жыл бұрын
You’re very welcome!
Amazing video!! I think this is my first time that I've actually enjoyed pathophysiology! Regards from a Kuwaiti PhD student, cardiac rehab specialist, at Swansea University, UK Fatimah
@HealthEdSolutions
3 жыл бұрын
Thank you for the support!
Thank you sir ... this is a very nice lecture to understand the the two types of diabetes and the long term effects
@HealthEdSolutions
3 жыл бұрын
Thanks for watching:)
a great video and very helpful. thank you.
you my friend are a genius.! i love all your videos. makes it so easy to understand
@HealthEdSolutions
3 жыл бұрын
You’re welcome. Glad you found it helpful!
Instructor here. Thanks for showing me some easier ways to explain this to students.
@HealthEdSolutions
3 жыл бұрын
You’re welcome. Glad you found it helpful!
Great explanation sir
thank you for this amazing lecture
@HealthEdSolutions
3 жыл бұрын
You’re welcome. Glad you found it helpful!
Very good work.
nice lecture, easy to understand, thank you
@HealthEdSolutions
3 жыл бұрын
Thanks for watching!
Very clearly explained on how compications occur and what goes on.. SUPERRRRRRRRRRRRRR
@HealthEdSolutions
3 жыл бұрын
Thank you!
Hello Dr. Wolf Thank you for this video it is very helpful. Thank you.
@HealthEdSolutions
3 жыл бұрын
Thank you Kevin!
Wow! I'm glad I found this before my test!!
@HealthEdSolutions
3 жыл бұрын
Thank you so much!
great vid! indeed, a helpful one especially for us nursing students to fully understand DM. thanks!
@HealthEdSolutions
3 жыл бұрын
Thank you for tuning in!
Thank you, very easy to understand. Animations really helped
@HealthEdSolutions
3 жыл бұрын
You’re welcome. Glad you found it helpful!
Great video!!! Highly recommended along with his other videos to medics.
@HealthEdSolutions
3 жыл бұрын
Thanks so much!
Great video. Thank you. Was left wondering why the video finished so abruptly though.
@HealthEdSolutions
3 жыл бұрын
You’re welcome. Glad you found it helpful!
i wish my teacher is YOU !! .. this would be soo much easier for me not sleeping in classes.... and understanding everything!! thanks for ur videos really help... please post some more!! =)
@HealthEdSolutions
3 жыл бұрын
Thank you!
Thanks a lot for this lecture. Really helped me :)
@HealthEdSolutions
3 жыл бұрын
You’re welcome. Glad you found it helpful!
Excellent, thank you...
@HealthEdSolutions
3 жыл бұрын
Thank you 🙏🏼
Very good lesson
@HealthEdSolutions
3 жыл бұрын
Thanks for the feedback! We will be rolling out new lessons soon. Keep watching, we appreciate the support!
Well made, thanks doc.
@HealthEdSolutions
3 жыл бұрын
Thanks for watching!
Hey, thanks this video has helped me understand the difference between type 1 and type 2 diabetes.
@channnelzita4235
8 жыл бұрын
+ John Kamau
@HealthEdSolutions
3 жыл бұрын
Thanks for watching John!
@HealthEdSolutions
3 жыл бұрын
Thanks for watching Channel!
awesome video. ....
@HealthEdSolutions
3 жыл бұрын
Thanks for your feedback and thank you for watching.
Great lecture sir
@HealthEdSolutions
3 жыл бұрын
Thank you so much!
Great work indeed. Thanks for sharing. Need of the hour as diabetis is increasing like anything now in India.
very informative thank you
Great and informative video.
@HealthEdSolutions
3 жыл бұрын
Thank you!!
Great video!!!!
@HealthEdSolutions
3 жыл бұрын
Thank you:)
Brilliant for My Remedial A&P Studies
@HealthEdSolutions
3 жыл бұрын
Glad it helped!
thank you. I don't know how I will remember all this stuff!
@HealthEdSolutions
3 жыл бұрын
You’re welcome. Glad you found it helpful!
thanks for the review
@HealthEdSolutions
3 жыл бұрын
Thanks for watching!
Finally Its clear! Thank you
@HealthEdSolutions
3 жыл бұрын
Thanks Belinda!
Great video thanks for helping me study for my exams in a non text book way. My question would be how does exercise affect insulin levels.
Excellent!!!!!
@HealthEdSolutions
3 жыл бұрын
Thank you!
Thank you Dr. Wolf. I wish you were my professor
@HealthEdSolutions
3 жыл бұрын
Thank you Diem!
Good information
@HealthEdSolutions
3 жыл бұрын
Glad it was helpful!
Late clinical complications are:1 Macrovascular complications, eg larger blood vessels like coronary and cerebral arteries may become prone to occlusion. 2 Microvascular complications-damage to small vessels eg fine capillaries in eye and kidney causing retinopathy and nephropathy respectively. 3 Microvascular damage to blood vessels in skin may cause lesion- dermopathy and 4 Peripheral nueropathy where peripheral nervous tissue mainly sensory nerves can become progressively damaged.
The video is great. Where is tge rest of the video?
@HealthEdSolutions
3 жыл бұрын
Thanks for the feedback! We will be rolling out new lessons soon. Keep watching, we appreciate the support!
Brilliant video! Thanks for sharing :) Was just wondering if you also happened to know the link between Type 1 Diabetes and HLA types DR3 and DR4?
nice lecture and very helpful especially in africa where we are lacking medical lecturers
@HealthEdSolutions
3 жыл бұрын
Glad it was helpful!
Thanks so much
amazing as usual, thanx alot 😊
@HealthEdSolutions
3 жыл бұрын
You’re welcome. Glad you found it helpful!
wow...you are an excellent educator and i like your explanation really. would you mind please telling my how to access to your power points or handouts? Thank you very much
thank you
@HealthEdSolutions
3 жыл бұрын
You're welcome and thanks for watching!
excellent!
@HealthEdSolutions
3 жыл бұрын
Thank you!!
good job sir thank you
Well done!
@HealthEdSolutions
3 жыл бұрын
Thank you!
easy to understand, can I embed this video on my blog?
Very nice
@HealthEdSolutions
3 жыл бұрын
Thank you!
GOOD. I learnt more in this 25 minute video than I did in my entire semester for cardiometabolic (4th year uni) about diabetes. Failed my practical because I gave a dismal answer to the client in why they are at risk of diabetes (with PAD, HTN and dyslipidemia). I guess I would answer that now as; as you have high levels of circulating fatty acid due to your dyslipidemia diagnosis, this causes increased inflammatory hormones which damage 2nd messenger system that works to release insulin. How would I link this back to HTN and PAD though?
@HealthEdSolutions
3 жыл бұрын
Awesome feedback! Appreciate hearing such great feedback:)
Andrew, as always legendary videos. You should add more information on about me section ... give more info of who you are and what you did ... just saying
excellent
@HealthEdSolutions
3 жыл бұрын
Thanks!!
Is there a second part? Thanks for the vid BTW
@HealthEdSolutions
3 жыл бұрын
Thanks for the question. We will ask Dr. Wolf and see what he says!
You are amazing sir. Make some more tutorials to help us please v
@HealthEdSolutions
3 жыл бұрын
Thanks for the feedback! We will be rolling out new lessons soon. Keep watching, we appreciate the support!
Thank you,
@HealthEdSolutions
3 жыл бұрын
You’re welcome. Glad you found it helpful!
really great video. sir how does polyphagia occur in diabetic patients?
@HealthEdSolutions
3 жыл бұрын
Thanks for the question. We will ask Dr. Wolf and see what he says!
Thanks
Triglycerides are derived not only from fats in the diet but also sugar (carbs and simple), alcohol, and excess calories in general. I think it's important to note this so as not to demonize fats in the diet specifically. Please correct me if I'm wrong.
@HealthEdSolutions
3 жыл бұрын
Thank you for sharing your feedback.
Do you have a video of diabetes and pathophysiology that links to chronic venous ulcers?
@HealthEdSolutions
3 жыл бұрын
Hi Liz, we will be rolling out new lessons soon. Keep watching, we appreciate the support!
Where is the next lecture after this?
@HealthEdSolutions
3 жыл бұрын
More to come!
tnx !!!!! תודה
C-peptide, a component of proinsulin (precursor to insulin) declines in DM1. It apparently plays a protective role in preventing beta cell destruction; therefore less C-peptide will accelerate decline in beta cells. The autoantibodies and cytotoxic T cells will continue to destroy beta cells unabated. McCance & Huether, 2010 - pathophysiology: a biologic basis for disease in adults and children - pg. 748
I'll take the survey if you are still in need of participants - the pop-up at the end of the video does not open a URL for some reason.
@HealthEdSolutions
3 жыл бұрын
Thanks so much!
hello Mr, Wolf, i wanted to thank you for explaining the patho beyond diabetes and i truly appreciate it! i am currently trying to answer this essay question, and i wanted to know what would be your input in regards to this question? A 28 yo Caucasian male with a history of Type I Diabetes presents to the clinic for his annual physical exam. While taking his history he states that he took 10 units of Regular Insulin prior to leaving for the clinic but forgot to eat lunch. what would you do?
Hi, where would Hyperglycemia fall in? is hyperglycemia part of type 2 diabetes?
Hi thanks a lot. Can I ask are the neurological complications eg sensory loss in the feet die to reduce BS to nerves and they die? Thanks
@HealthEdSolutions
3 жыл бұрын
Thanks for the question. We will ask Dr. Wolf and see what he says!
Hi! How do you do these video? I mean what program or application are you using? I was hoping to use this on a school presentation.
@HealthEdSolutions
3 жыл бұрын
Thanks for your inquiry. The whiteboard lessons are created using a Wacom Bamboo tablet. Thanks for watching!
I did appreciate the video, but don't forget the simple stuff. like osmotic effects. No mention of the three "P's"??? The typical early indicators of diabetes are Polyurea, Polydipsia, and Polyphagia. (Urinating frequently, Thirst, and hunger). Another osmotic effect is increased intra-ocular pressure.
@HealthEdSolutions
3 жыл бұрын
Thank you for sharing your feedback. The Health Ed Solutions team is happy you found the lesson helpful!
The high glucose level will form plaques on the wall of blood vessel and it makes blood vessel hard (arteriosclerosis), this will cause poor blood circulation, and high glucose concentration serves as food to the bacteria.
Mr. Wolf, You said FFA causes increased cytokines and inflammation which may be cause for inhibiting the second messenger system. My question is, why wouldn't anything that causes increased levels of cytokines and inflammation do the same thing? How can you pinpoint only Free Fatty Acids as the cause and in the same note claim it's from the processes that FFA induce? Multiple other stimuli have the same inflammatory affect, no?
@HealthEdSolutions
3 жыл бұрын
Great question. We will check with Dr. Wolf and see what his input is. Thanks for watching!
Hi Dr. Wolf, These videos are so helpful! I am trying to get ready for my final in Patho and can't figure out what pathway is activated in the kidneys to increase urine and excrete the additional serum K+ during DKA? Is it the RAAS? Thank you!
@HealthEdSolutions
3 жыл бұрын
Thanks for the feedback! We passed it along to the Health Ed Solutions board!
Please add avedio about LFT's. Thanks
Very nice video Andrew... Can you tell me more about including potassium in diet? and is DKA common in Type -1 or 2?
@HealthEdSolutions
3 жыл бұрын
Thanks for watching! We’ve passed along the question to the Health Ed Solutions medical review team!
hello there i was wondering if you could explain the reason why ketoacidosis is more pronounced in type I diabetics rather then type II, i was think because of complete lack of insulin in type I the patient is more likely to burn the fats while in type II even though there is insulin resistance some tissues in the body show some response to the insulin so ketoacidosis doesn't manifest to the same extent. hope you can clear up my understanding
@HealthEdSolutions
3 жыл бұрын
Thanks for the question. We will ask Dr. Wolf and see what he says!
sir..how does DM patient experienced polyuria, polydipsia and polyphagia?
@HealthEdSolutions
3 жыл бұрын
Thanks for the question. We will ask Dr. Wolf and see what he says!
Are arthereomas causing trouble with the microvessals in the kidney? Some renal problem that is causing the hyperglycemia in the first place?
hello sir, I would like to ask you the roll of C-peptide in DM1 ? thank you
@HealthEdSolutions
3 жыл бұрын
Thanks for watching! Your question has been passed along to the Health Ed Solutions medical review board!
This is a very good video Mr Wolf, but I have the same question with Sara Leland. If the second messenger system of the liver cells in prediabetic condition (type 2 DM) is blocked, how the patient can compenzate just fine? Since the glucose transporters on the plasma membrane of the hepatocytes do not brink the glucose molecules in the cytoplasm. How the patient can have a normal glucose level in the blood at this prediabetic state? I am looking forward for your reply... Thank you :-)
@HealthEdSolutions
3 жыл бұрын
Great question. We will check with Dr. Wolf and see what his input is. Thanks for watching!
hello sir, how in patient with diabetes type 2 will be a block in second messenger ...you mentioned something about cytokines and fatty acid what is the relationship between them . thank you
@HealthEdSolutions
3 жыл бұрын
Thanks for the question. We will ask Dr. Wolf and see what he says!
Dr. Wolf: OK, I know to check for microalbumuria in Type II DM every six months or so. Then what, if a patient does have microalbuminuria? If they are already taking an ACE inhibitor, do we send to a nephrologist for evaluation promptly if there are no symptoms? Do we work on controlling blood sugars first, then refer if microalbumuria persists? I am participating in the care of a few patients that have been taking their meds intermittently (HbA1C 11, etc)
@HealthEdSolutions
3 жыл бұрын
Great question. We will check with Dr. Wolf and see what his input is. Thanks for watching!
what about do action of insulin producing hypoglycaemia ???
@HealthEdSolutions
3 жыл бұрын
Thanks for the question. We will ask Dr. Wolf and see what he says!
This made me cry because complicated diabetes killed my mom.
how can I know that the patient have insulin shock and what do I have to do
@HealthEdSolutions
3 жыл бұрын
Thanks for the question. We will ask Dr. Wolf and see what he says!
That's what I wanted to know.
@HealthEdSolutions
3 жыл бұрын
Thanks for watching!
Hi Andrew, this is very helpful for my patho class. It is interesting that you said a virus such as measles or mumps. Could vaccination be the trigger to that autoimmune response?
@HealthEdSolutions
3 жыл бұрын
Thanks for watching! We have passed along your questions to the Health Ed Solutions medical content team!