Thanks! KZread extends the reach of your talent for explanation to people all over the world

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

Thanks very much Andrew. I liked that you kept the normal anatomy brief at the beginning and then went straight onto the subject of the video. Thank you :)

the intuitive, conversational nature is easier to follow than other sources when following just audio. Many thanks!

@HealthEdSolutions

3 жыл бұрын

You are very welcome and appreciate the kind words.

Thanks Andrew. I've just been diagnosed with stable angina and scheduled for a triple bypass, and the topic has suddenly become fascinating. Thanks for explaining it clearly for laymen. Now, not only do I now have more of an understanding of atherosclerosis, I can now have a more informative and intelligent discussion with the cardiologist.

I watched this video a year and a half ago, and really appreciated it's depth. It explains the process of atherosclerosis better than any other site I have found. But for the past year, I have not been able to find this video to re-watch and it has been driving me crazy (I couldn't remember my original search terms). I'm so happy to have finally found it again. I will definitely be watching more of his lessons going forward. Thank you, Dr. Wolf

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

i'm a 5th year med student and your video helped me understand atherosclerosis way more. clearly. words can not express my gratitude.

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

Great lecture! You make it so easy to understand.

very clear, forward and easy to understand, thank you

Excellent tutorials!

A great Video as usual, really appreciated.

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

I find your lectures excellent and a welcome addition to the information I am learning in class. I like the way you break things down and makes it a little easier to understand

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

Seriously amazing talk! Makes it easy to understand.

@HealthEdSolutions

3 жыл бұрын

Keep watching, we appreciate the support!

Hi Andrew your videos are awesome. Keep on posting wonderful articles. Very edicative for anyone in medical line. God bless you for your deeds

@HealthEdSolutions

3 жыл бұрын

Hi Sunish, thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

great & usefull... thank you sir for sharing.

@HealthEdSolutions

3 жыл бұрын

Thanks for watching! Glad it was useful!

i have to congratulate you on your very visual and informative lectures. I absolutely love them.

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

What a great, simple explanation of the process. Thank you.

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

Wow. That made a lot of sense, thank you.

Great video! Thank-you so much. It helped me understand so much better!

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

Great breakdown! Thanks👍🏼

@HealthEdSolutions

3 жыл бұрын

Thanks Cam!

what an amazing video!! thank you very very much

@HealthEdSolutions

3 жыл бұрын

Thank you for the feedback! Glad you found it helpful!

Great video made my nursing reading easier and make so much sense. Cardiac is hard enough thanks for making it less complicated

@HealthEdSolutions

3 жыл бұрын

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Very clear. Thanks very much.

BIG THANKYOU for this great visual explanation of the pathophys of athersclerosis! I am studying ACS as part of my post-grad studies in my Emergency Nursing and I found this explanation of yours EXTREMELY useful in understanding the whole complicated process. I love your diagrams... will be copying them in my notes :) Big Hello from Perth, Australia!

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

i m a pharmacy student and big thank you to you all the way from australia

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

Such a helpful video thank you!!!

@HealthEdSolutions

3 жыл бұрын

You're welcome and thanks for watching!

Wow.. i got more out of that than in my 3 hour class we had on the subject! thank you.

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

Thank you for this, excellent

@HealthEdSolutions

3 жыл бұрын

You're welcome and thanks for watching!

fantastic ! :) :) i love this way of education :)

This was very helpful, thank you so much.

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

really great video keep it up

very helpful videos .thank u so much

THANK YOU VERY MUCH.DOC!!!

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

clear understanding!!! helped with my exam

@HealthEdSolutions

3 жыл бұрын

Thank you for the feedback! Glad you found it helpful!

Thank you for the awesome explanation..

@HealthEdSolutions

3 жыл бұрын

You're welcome and thanks for watching!

Using your videos for my CR exam in Physio, so helpful thank you very much, my sort of learning!

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

THANKS..MADE THE TOPIC SO EASY TO UNDERSTAND

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

great basic intro to atherosclerosis pathophysiology - thanks

@HealthEdSolutions

3 жыл бұрын

Thank you!

very helpful! thank you Andrew :)

@HealthEdSolutions

3 жыл бұрын

Thank you for watching. Glad it helped!

it is a good idea to see this vedios

Thank u very very very much.... well Job doctor...

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

Thank you! This really helped me in my nutrition studies. Very easy to understand :)

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

awesome video. thanks so much! keep up the good work sir. :)

I have an exam next week for my Adult Nursing course (Scotland) and your videos are great for revision! The information you give links perfectly to my lecture notes but I am very much a visual learner and so your videos are great for me. Thank you so much for spending time to make them and kindly sharing them with the KZread community. Oh, and something tells me your view count is going to increase significantly over the next week. My class are sharing your videos on our private facebook page!

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

Wonderful video! Makes so easy to understand a very important topic!

@HealthEdSolutions

3 жыл бұрын

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Awesome video before a pathophysiology final tomorrow !

Wonderful lecture

Very good and easy explanation,well done

@HealthEdSolutions

3 жыл бұрын

Thank you for the feedback! Glad you found it helpful!

Really helpful, thanks x

@HealthEdSolutions

3 жыл бұрын

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Very helpful!!

Thanks for writing back.

thank you so much.it has been helpful....

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

I suppose it should be monocyte in the vessel and will convert to macrophages later in intima.. Correct me if im wrong :)

Thank you so much

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

Gr8 work thnx

thank you

very nice presentation

@HealthEdSolutions

3 жыл бұрын

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THANK YOU!!!

@HealthEdSolutions

3 жыл бұрын

Keep watching, we appreciate the support!

My prof tolled us to study the kinds of atherosclerosis plaques I was reading Robbins basic pathology book 7th edd chapter 9 and I still dont understand what kinds did he mant . Your help will be so gratitude! Thank you!

thank you very much

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

Thankyou , this has helped me so much : D

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

Andrew Wolf you did not talk about the process of CALCIFICATION, when the fibrous cap becomes stiffer and more brittle and more prone to rupture. The calcification process also affects blood pressure behavior due to the lesser elasticity of the arterial volume...

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

Thank you Sir. Your lectures are just out of this world. Am trying to locate your pathphys channel. May God Bless you n yr loved ones. :-)))

@HealthEdSolutions

3 жыл бұрын

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excellent

Excellent presentation - however no mention of the role of calcium deposition within the plaque formation (?)

GREAT

Cheers andrew

amazing thank you ! :)

@HealthEdSolutions

3 жыл бұрын

Thank you for the feedback! Glad you found it helpful!

thank you sir

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

Hi, I was wondering if you could possibly cover physiology of aging? Thank you so much for all your videos and teachings, they are helping me through medical school.

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

Thank you, it is a very helpful video. Could you maybe make one about hyperlipidemia?

Awesome video! i just dont understand how the plaque continues growing under the fibrin, when is not exposed to more LDL... THANKS!

excellent lecture and pictorials. there was a lot of hesitation though

@HealthEdSolutions

3 жыл бұрын

Thank you for the feedback! We will be releasing a new and improved version soon. Thanks for watching.

Fantastic explanation……now for the million dollar question……….how do we reverse it or fix it?

Thanks

@HealthEdSolutions

3 жыл бұрын

You’re welcome. Glad you found it helpful!

Hi Andrew, thank you for the video. How actually can the plaque grow in size after a fibrous layer is formed around the plaque as the opening in the intema is closed by the fibrous layer so how they enter?

Awesome video once again. I am just now wondering how can LDL molecules cause inflammation by themselves?

Great lecture! it's true that this visual way of learning makes it sooo much easier than just reading my lecture notes- much thanks! One thing though- at the end of the lecture you mention the clot breaking off and causing an embolism somewhere- can the plaque break off and do this too? Is this also called an embolism?

great video than you

@HealthEdSolutions

3 жыл бұрын

Thank you Omar!

What happened with the original Andrew Wolf channel???

Thankfully my exam has been a good excuse for staying indoors and studying. I can see the snow on the hills from my window right now :/ It doesn't look too inviting!

thanks. easy to understand even for a lay man.

@HealthEdSolutions

3 жыл бұрын

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Thumbs up! :)

Very good explanation. Thank you! Do macrophages go into the break in the intima first, or do monocytes come first and then convert them to macrophages?

@HealthEdSolutions

3 жыл бұрын

Thanks for the question. We've passed it along to the Health Ed Solutions medical review board.

Hi - Could you expand on how DM contributes to the plaque formation, inflamation or maybe the rupture?

@HealthEdSolutions

3 жыл бұрын

Thanks so much for your inquiry. We have passed this question on to our medical review team. Thanks again for watching!

it helped me a lot....its a different approach to pathophysiology and i enjoyed ur lecture.i would like to ask u if der is any lecture regarding how tobacco causes endothelial injury i.e by antiprotease hypothesis and antioxidant mechansim.if u included these explanations under any other disease plz let me know.... plz sir

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

Hello, first of all thank you for the wonderful informative video. I enjoyed it. I was just wondering if you have a made a video about the role of PI3Ks in cardiovascular disease? Thank you

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

Nice video. Why doesn't the platelet plug prevent the LDL deposition? Once the fibrous plaque forms, why doesn't that prevent further LDL deposition? Why doesn't the coagulation/inflammation process proceed as it does in other locations and produce proper healing?

@HealthEdSolutions

3 жыл бұрын

Thanks so much for your inquiry. We have passed this question on to our medical review team. Thanks again for watching!

So helpful thank you. May I please know how hypertension, Hyperlipdaemia, diabetes and smoking cause damage to the endothelial cells

@HealthEdSolutions

3 жыл бұрын

Thanks for the question. We've passed it along to the Health Ed Solutions medical review board.

Subscribed soon after watching this. such a good revision tool for me, and i'm doing a degree! One question though; after the fibrous cap has formed isn't there another process of 'calcification'? if so what actually causes it?

@HealthEdSolutions

3 жыл бұрын

Thanks so much for your inquiry. We have passed this question on to our medical review team. Thanks again for watching!

very good lecture, you just taught me the easy way to understand atherosclerosis process. theres no much feedback from me, but you may just speak more clear and louder. because in some part, your voice getting quite, especially when you saying the important point. thank U so much, keep publish more lectures about important topics :)

@HealthEdSolutions

3 жыл бұрын

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THANK YOUUUUUUUUUUUUU VERY MUCHHHHH!! :>>>>

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

Andrew is the particle size of the ldl relevant or will all ldl deposit in this way?

@HealthEdSolutions

3 жыл бұрын

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Question: in stage 3. Fibrous plaque. You said it won't have contact with the blood stream anymore. So how can it grow in size if LDL's are floating in blood stream? Just got confused in this part. Thank for you videos. It's very helpful and I'm a fan!

@HealthEdSolutions

3 жыл бұрын

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What causes the LDL particles to stick to the tunica intima and get under the layer ? What attracts them ? Chemokines, like what happens with lymphocytes ?

@imagination7710

8 жыл бұрын

+Joe Kensei As far as I know, hyperlipidaemia contributes to driving the LDL into the intimal layer. LDL is retained via association of ApoB-100 with negatively-charged proteoglycan residues in the ECM.

@HealthEdSolutions

3 жыл бұрын

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will it be any time soon Sir?

@HealthEdSolutions

3 жыл бұрын

We will be rolling out new lessons soon. Thanks for watching.

Anderw Wolf its i a great job thnx )) would u make a video about coma , collapse shock thank you

@HealthEdSolutions

3 жыл бұрын

Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.

thanks alot doctor ***** ... but i have one question after the fibrous plaque formation ...from where does the LDLs come from ?? i mean Macrophages will engulf the LDLs and will grow to some distance ...then how does it keep growing ?? ....or is that the LDL enter in a very large quantity that it takes alot of time to be engulfed by macrophages ?? please anyone answer :D

@joshuasmith4906

10 жыл бұрын

I believe that the LDL is recruited by the endothelial cells, since LDL contains cholesterol and other molecules that the cells need - after all, the reason that LDL is circulating is to bring nutrients to the cells. Therefore if you have a high level of LDL in the blood over an extended period of time, more of it is recruited and also more of it can be oxidized (this isn't mentioned in the video but oxidation of LDL is pretty bad and can increase inflammation because the immune system recognizes the OxLDL (it can even produce antibodies against it)). Therefore the oxidation of LDL only increases the rate of development of atherosclerosis, since it increases inflammation. Even though the fibrous plaque covers the developing core, the endothelial cells below it still the LDL contents. I'm not a doctor (just a student) so take this with a grain of salt, but I hope that it helps.

@mone3ybagz

10 жыл бұрын

we're all students here :P ....thanks alot for helping i got it know :)

@HealthEdSolutions

3 жыл бұрын

Thanks so much for your inquiry. We have passed this question on to our medical review team. Thanks again for watching!

how does diabetes damage the endothelial layer?

@HealthEdSolutions

3 жыл бұрын

Thanks so much for your inquiry. We have passed this question on to our medical review team. Thanks again for watching!

@poochyboi

3 жыл бұрын

@@HealthEdSolutions 5 years later and i still don't know how diabetes destroys the endothelial layer. Perhaps I will know in another 5 years.

i´m from colombia too. this is an academic project, not your business room.

thank u...thanks a lottt it ws great explaination...with lots of patience,,,,thumpsup..