Parkinson's Disease Drugs

Official Ninja Nerd Website: ninjanerd.org
You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:
www.ninjanerd.org/lecture/par...
Ninja Nerds!
In this lecture Professor Zach Murphy will be presenting on Parkinson's Disease Medications. During this lecture we will start by reviewing the Basal Ganglia Anatomy and Physiology. We will also be reviewing the direct and indirect pathway that is affected with Parkinson's disease. We will then transition into the various drug categories used to treat Parkinson's which includes Levodopa or L-Dopa, Dopamine Agonists, COMT inhibitors, MAO-B inhibitors, Amantadine, and Anticholinergics. We hope you enjoy this lecture and be sure to support us below!
Table of Contents:
0:00 Lab
0:07 Parkinson’s Disease Medications Introduction
1:20 Basal Ganglia Anatomy
4:23 Direct vs. Indirect Pathway
18:23 Pathophysiology of Parkinson’s Disease
21:26 Drug Classes for Parkinson’s Disease
24:36 Mechanism of Action
38:51 L-Dopa + Carbidopa
1:00:22 Dopamine Agonists
1:06:08 COMT-Inhibitors
1:11:39 MAO-B-Inhibitors
1:20:12 Amantadine
1:27:10 Anticholinergics
1:31:18 PD Medications - Practice Problems
1:36:13 Comment, Like, SUBSCRIBE!
Supplemental Lectures:
Basal Ganglia - • Neurology | Basal Gang...
Pharmacology Source:
Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition.
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#ninjanerd #parkinsonsdisease #pharmacology

Пікірлер: 187

  • @aneesazafar9646
    @aneesazafar9646 Жыл бұрын

    You are remarkable, I have never met a teacher like you.

  • @smoovlatino
    @smoovlatino7 ай бұрын

    I am speechless at how gifted you are in teaching. We must protect this man.

  • @HarshPatel-he2vh

    @HarshPatel-he2vh

    2 ай бұрын

    From whom? no one hates him😭

  • @deerfashion
    @deerfashion Жыл бұрын

    Starting an assignment on PD meds for my pharmacology class today! SO perfect!😍

  • @silviamontisci6399
    @silviamontisci6399 Жыл бұрын

    Italian medical student here! I'm glad I found you on YT, you're such a life-saver. Thank you for sharing your passion for these subjects, you're amazing man! (and your staff too, of course)

  • @faiza.m9974
    @faiza.m9974 Жыл бұрын

    Amazing this video save me, I spend many days to read textbooks and watching my lectures and I feel so dumb but now this video is totally make sense to me and put everything I’ve read together, thank you so much 🎉

  • @khalilahd.
    @khalilahd. Жыл бұрын

    So helpful. Thank you! ❤

  • @yvonnevillalba7722
    @yvonnevillalba7722 Жыл бұрын

    You truly are the best teacher ever! Thank you for this video.

  • @Lotus-iz3ic
    @Lotus-iz3ic Жыл бұрын

    Actually I've been struggling with Parkinson's drugs and mechanisms as I used to hate pharmacology the first medical year in college but this video definitely make it way too easier , I am really feeling grateful, thank you a lot ❤❤❤❤ you are the greatest 💪🏻

  • @madisonwatt329
    @madisonwatt3298 ай бұрын

    Your videos are amazing! Clears up so much information left out by professors! Thank you for everything you do.

  • @AnnMulvihill-lt9qz
    @AnnMulvihill-lt9qz10 ай бұрын

    You are Excellent. Great teacher. Thanks from retired RNBSN with Parkin sons. Still with thrist for knowledge to understand. Thanks.

  • @chinnyogbonna6506
    @chinnyogbonna6506 Жыл бұрын

    I love your passion and teaching, always amazed. Thank you very much.

  • @steveh1460
    @steveh1460 Жыл бұрын

    Love your passion for teaching! Thank you!

  • @kathikloeckner6118
    @kathikloeckner6118 Жыл бұрын

    I love your memory and your passion! ROCK STAR!

  • @niharikasaraf3506
    @niharikasaraf3506 Жыл бұрын

    I never bothered learning WHY we used COMT and MAO B inhibitors before this video, damn thank you!!

  • @leticiadermith9832
    @leticiadermith9832Ай бұрын

    You have a gift and I am so grateful for your existence on this earth and time.

  • @direxsama258
    @direxsama258 Жыл бұрын

    didnt watch this yet but without doubtes i know it will be a BANGER Thank you Dr

  • @s_l_m__
    @s_l_m__ Жыл бұрын

    Extraordinarily well made video. Thank you, Zach

  • @irereomio1797
    @irereomio17973 ай бұрын

    Love love your videos. Thank you

  • @sadiajafar5792
    @sadiajafar5792 Жыл бұрын

    I love the way you you teach I think your are the bestest teacher in this whole world 🌍

  • @ayanafrancis6294
    @ayanafrancis6294 Жыл бұрын

    You are a saviour .Thank you zach🔥

  • @ella-meow1116
    @ella-meow1116 Жыл бұрын

    please please continue making pharmacology videos ,as pharmacy student i find these so helpful thank you for your effort

  • @robinkaczanowski7970
    @robinkaczanowski797014 күн бұрын

    Love this❤❤❤❤Need more! Excellent Teacher.

  • @mariapereiramd7173
    @mariapereiramd7173 Жыл бұрын

    Thank you for this video!

  • @jis2937
    @jis2937 Жыл бұрын

    I’m grateful for your existence, you do matter & we appreciate u

  • @kda-2672
    @kda-26722 ай бұрын

    Thank you so much ninja nerd❤ you're a life saver

  • @mohamedkhyrat7372
    @mohamedkhyrat73726 ай бұрын

    Thank you so much for everything❤

  • @tanveerabdullah3297
    @tanveerabdullah3297 Жыл бұрын

    Kindly make videos on antidepressents and anxiolytics ...plz

  • @biybimaryamjoldasbaeva506
    @biybimaryamjoldasbaeva5064 ай бұрын

    Thanks a lot for the perfect lecture!

  • @wombat2379
    @wombat2379 Жыл бұрын

    great job!! Thank YOu!!

  • @mariakara4848
    @mariakara48488 ай бұрын

    the best teacher ever🌹

  • @fallenangel8785
    @fallenangel8785 Жыл бұрын

    you are a great human being

  • @mmdohhmod7622
    @mmdohhmod7622 Жыл бұрын

    You are awesome teacher, Man... Thanks for everything

  • @emacroitor1053
    @emacroitor1053 Жыл бұрын

    thank you for your help! I am grateful! 😇

  • @faisalqasmi9543
    @faisalqasmi9543 Жыл бұрын

    Be healthy sir 🙏 we really need you

  • @francescacovre7526
    @francescacovre7526 Жыл бұрын

    You are my saver for any exam preparation

  • @katarinatysse6086
    @katarinatysse608610 ай бұрын

    Thank you so much!!

  • @mmsah30
    @mmsah30 Жыл бұрын

    i love u man, u made it easy on me to understand the topics

  • @stephanieslay2976
    @stephanieslay2976Ай бұрын

    I can't thank you enough for this video 🙏 You're just awesome ❤

  • @oscarpaz6162
    @oscarpaz61622 ай бұрын

    thank u so much for this video zach 🥰

  • @jesuschaudhary5458
    @jesuschaudhary5458Ай бұрын

    Really amazing ❤❤!!

  • @monkearmy2216
    @monkearmy2216 Жыл бұрын

    I really like these videos, hope you get more recognition

  • @hubb4manu
    @hubb4manu Жыл бұрын

    Thank you so much.

  • @goosey1055
    @goosey10555 ай бұрын

    Excellent video.

  • @ricardor2166
    @ricardor216611 ай бұрын

    Great quality

  • @maalusn934
    @maalusn93410 ай бұрын

    Thank you so much❤

  • @sangsenglay9989
    @sangsenglay9989 Жыл бұрын

    thank you so much sir, may god bless u

  • @asmakhalid8873
    @asmakhalid88736 күн бұрын

    Thank you so much💕

  • @vetnet100
    @vetnet100 Жыл бұрын

    Nice video. Helpful and informative

  • @universeusa
    @universeusa Жыл бұрын

    You are one of a kind 👏👍

  • @chipochuumpu6602
    @chipochuumpu66029 ай бұрын

    Thank you!

  • @armelagjini
    @armelagjini Жыл бұрын

    you are the best! god bless you

  • @SH-eh6wx
    @SH-eh6wx4 ай бұрын

    God bless you in the ways you do not even imagine!

  • @kirandeepkaur6265
    @kirandeepkaur62652 ай бұрын

    Great teaching process👍🏻👍🏻👍🏻👍🏻

  • @NishitaKinger-hr4ec
    @NishitaKinger-hr4ec5 ай бұрын

    Great Work!

  • @dindaire
    @dindaire Жыл бұрын

    Omg thank you!! I take my PANCE in a few weeks and your videos are so good

  • @Gandalf-DZ
    @Gandalf-DZ Жыл бұрын

    Gotta love this dude

  • @banub3111
    @banub3111 Жыл бұрын

    Thank you ❤

  • @ahmedfathi3217
    @ahmedfathi3217 Жыл бұрын

    I love your videos. Definitely one of the best out there. Also, nice glasses 🤓

  • @malikihamski4265
    @malikihamski4265 Жыл бұрын

    Sir I appreciate your work Thank you so much A love from TANZANIA.......!

  • @hilinatakele5021
    @hilinatakele50214 ай бұрын

    Thank you so much

  • @nidallkl8559
    @nidallkl8559 Жыл бұрын

    keep doing this thank youu helps a looot

  • @norasaf7838
    @norasaf7838 Жыл бұрын

    The best Ph of medicine

  • @eurobeatsexplorer
    @eurobeatsexplorer Жыл бұрын

    Thank you guys!!!

  • @buombothmut
    @buombothmut6 ай бұрын

    A great scientist ever❤

  • @johntom2362
    @johntom23627 ай бұрын

    Thank you sir

  • @mrsamandabernier
    @mrsamandabernier Жыл бұрын

    Amazing 👏

  • @iulianaandra9699
    @iulianaandra9699 Жыл бұрын

    Thank you!❤

  • @PranamyaPednekar
    @PranamyaPednekar2 ай бұрын

    thank you so much

  • @user-hq2xw3dp7f
    @user-hq2xw3dp7f Жыл бұрын

    Thank you so much ❤❤❤❤

  • @jamiefootball2409
    @jamiefootball2409 Жыл бұрын

    cutest tutor out there xx

  • @azielmalili6516
    @azielmalili6516 Жыл бұрын

    You are a hero

  • @mohsward4708
    @mohsward4708 Жыл бұрын

    just superb

  • @owaisahmed7653
    @owaisahmed7653 Жыл бұрын

    outstanding all the time best teacher❤

  • @ellionorader3219
    @ellionorader3219 Жыл бұрын

    Thank uuuuu best teacher ever I used to follow You when the channel has some 70k so soproud that you ve reached the M You deserve mooooore

  • @zozoabdulkadir9642
    @zozoabdulkadir96427 ай бұрын

    You are amazing ❤

  • @yosun_job
    @yosun_job2 ай бұрын

    Thanks doc

  • @amine6005
    @amine6005 Жыл бұрын

    You are the best of all the time in saving med students life we are craving for more pharmacology

  • @zainabmaan5330
    @zainabmaan5330 Жыл бұрын

    You are amazing and vibrating

  • @user-sb7rs4tp2l
    @user-sb7rs4tp2l7 ай бұрын

    we need more pharmacology videos

  • @dailydoseofmedicinee
    @dailydoseofmedicinee Жыл бұрын

    Thanks

  • @zainabfarooq5263
    @zainabfarooq5263 Жыл бұрын

    I comment for you before I watch the lesson because I’m sure you are great

  • @deegallarupananda6927
    @deegallarupananda6927 Жыл бұрын

    Very useful

  • @drravikumar8122
    @drravikumar8122 Жыл бұрын

    amazing

  • @user-zx4mb3xv4p
    @user-zx4mb3xv4p9 ай бұрын

    thanks a lot for the way of informations 😘😘😘😘😘😘

  • @virginiabruno624
    @virginiabruno624 Жыл бұрын

    You are intelligent you go deep into it

  • @timwillebrand2001
    @timwillebrand200113 күн бұрын

    amazing video

  • @ashutoshsahoo1013
    @ashutoshsahoo10138 ай бұрын

    Finally All concept clear 😌Salute to your Passion and Strength. Love from Odisha.

  • @ranlove47
    @ranlove47 Жыл бұрын

    As always another great video. Wife recently diagnosed with Parkinson’s. Been doin a deep dive into high does of B1 (thiamine) for treatment. After adding it to the treatment made a huge improvement over the meds (Rytary $$$$$). Would love to see a deep dive into why/how this mechanism might work. Most doctors don’t know or haven’t heard of this treatment. Obviously no money to be made on a vitamin. Thanks again for you dedication.

  • @steveh1460

    @steveh1460

    Жыл бұрын

    That would be a great topic to cover!

  • @solomebihon2218
    @solomebihon22188 ай бұрын

    you are great God bless you the best teacher ever am medical student in east Africa Ethiopia

  • @ampala-oc3zt
    @ampala-oc3zt Жыл бұрын

    Perfect

  • @ladydeebigandcute2681
    @ladydeebigandcute26812 ай бұрын

    Let this man open his university ❤

  • @alishka0109
    @alishka0109 Жыл бұрын

    love you zachy

  • @Abdullah_DS
    @Abdullah_DSАй бұрын

    You know Zach that your vids are kind of entertainment!

  • @rmurthy5011
    @rmurthy5011 Жыл бұрын

    Very informative. Learnt a lot even as a geriatrics doctor. Perhaps include apomorphine in the drugs? Confess I love your explanation so much I don't want to go back to the books for that!

  • @user-ik8hw2jg8s
    @user-ik8hw2jg8s8 ай бұрын

    U R Great❤

  • @bharatmdrad7243
    @bharatmdrad724310 ай бұрын

    Thanks Ninjaners

  • @sadiajafar5792
    @sadiajafar5792 Жыл бұрын

    Amazing 🤩

  • @moloreanm1657
    @moloreanm1657 Жыл бұрын

    Nice vid! Now one about Huntington’s 😊

  • @jessicasmith6873
    @jessicasmith6873 Жыл бұрын

    I remember voting for pharmacology videos many months ago. I don't want to complain but I relied heavily on you to passing anatomy and now that I'm in pharmacology I'm gonna need you to hurry up 😜 . We did Parkinson medications last week 😞

  • @joelletinnock7227
    @joelletinnock7227 Жыл бұрын

    Awesome